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Dr. Azadeh Hekmat | Biochemical- Biophysics | Best Researcher Award

Professor at Science and Research Institute, Iran

Azadeh Hekmat is an accomplished Assistant Professor at Islamic Azad University, Tehran, specializing in biophysics with a focus on apoptosis, biomaterials, drug delivery, and nanotechnology. She earned her Ph.D. from the University of Tehran, where she investigated the effects of nanoparticles and doxorubicin on DNA and cancer cell apoptosis. Her postdoctoral work further explored biophysics applications. With a distinguished academic record, including top rankings in her M.Sc. and Ph.D. programs, she has published extensively in peer-reviewed journals and authored significant books on biophysics and spectroscopy. Hekmat’s expertise spans various laboratory techniques such as spectroscopy, cell culture, and molecular biology. She has received numerous awards, including Best Graduate Student and Best Teacher. Her professional memberships include the Biophysical Society and the Iranian Association for Plant Cell and Tissue Culture. Hekmat is recognized for her contributions to both fundamental and applied biophysics research.

Profile

Education

Azadeh Hekmat earned her Ph.D. in Biophysics from the Institute of Biochemistry and Biophysics, University of Tehran, Iran, between 2008 and 2013. Her doctoral dissertation, titled “The Synergistic Effects of Silver and Titanium Dioxide Nanoparticles and Doxorubicin on DNA Structure and Induction of Apoptosis in Breast Cancer Cell Lines: T47D and MCF7,” was awarded an excellent grade. She achieved the highest GPA in her cohort with a perfect 4.0/4.0. Prior to her Ph.D., Hekmat completed her M.Sc. in Biophysics at the same institute from 2005 to 2008, where her thesis focused on “The Effects of Temperature and pH on the Function and Structure of Choline Oxidase,” and she also graduated at the top of her class with a GPA of 3.8/4.0. Her foundational education includes a B.Sc. in Biology from Alzahra University, Tehran, completed in 2005.

Professional Experience

Azadeh Hekmat has built a distinguished career in biophysics and related fields, currently serving as an Assistant Professor at Islamic Azad University’s Science and Research Branch in Tehran since 2014. Prior to this role, she completed a postdoctoral fellowship in Biophysics at the University of Tehran from 2013 to 2014. Her academic journey began with a Ph.D. in Biophysics from the Institute of Biochemistry and Biophysics at the University of Tehran, where she specialized in the effects of nanoparticles on DNA and cancer cell apoptosis. Hekmat’s research and teaching experience is complemented by her role as the executive secretary for the 1st conference of Nano from synthesis to industry in 2016 and her leadership as Head of the Committee on Education and Research for the Iranian Association for Plant Cell and Tissue Culture from 2017 to 2024. Her expertise spans apoptosis, nanotechnology, and drug delivery systems.

Research Interest

Azadeh Hekmat’s research interests span a range of topics at the intersection of biophysics, nanotechnology, and molecular biology. Her work primarily focuses on understanding the mechanisms of apoptosis and the effects of bioelectromagnetics on cellular processes. She explores drug delivery systems, particularly the interactions between drugs and biomacromolecules, aiming to improve chemotherapy outcomes. Hekmat’s research also delves into the biological effects of microgravity, multidrug resistance, and nanotechnology. Her expertise extends to molecular dynamic simulations and stem cell bioengineering. Additionally, she investigates the structural and functional impacts of nanoparticles, such as silver and titanium dioxide, on DNA and cell lines. Through her studies, she seeks to advance the development of innovative therapeutic strategies and enhance our understanding of the molecular dynamics underlying cellular and biochemical processes.

Research Skills

Azadeh Hekmat possesses a robust set of research skills that underscore her expertise in biophysics and biochemistry. Her proficiency spans a wide array of techniques including spectroscopic methods such as UV-Visible, Fluorescence, FT-IR, and Circular Dichroism (CD) spectroscopy, as well as Dynamic Light Scattering (DLS). She is adept at Differential Scanning Calorimetry (DSC) and Isothermal Titration Calorimetry (ITC), crucial for studying molecular interactions and thermal properties. Hekmat’s experience in cell culture techniques includes Flow Cytometry, Fluorescence Microscopy, Electron Microscopy, Optical Microscopy, and MTT Assays, which are essential for evaluating cellular responses and drug effects. Her skills also extend to molecular biology methods like PCR and ELISA. This diverse expertise supports her research into apoptosis, drug delivery, nanotechnology, and microgravity biological effects, highlighting her capability to address complex biological and chemical phenomena.

Award and Recognition

Azadeh Hekmat has earned significant recognition throughout her career, reflecting her outstanding contributions to the field of biophysics. She was ranked 1st among her Ph.D. graduates and also received the Best Graduate Student Award from the University of Tehran in 2009. In 2010, she was honored with the Best Teacher Award at Islamic Azad University. Her academic achievements are highlighted by her top-ranked performance in both her M.Sc. and Ph.D. programs, where she excelled in coursework and research. Additionally, her contributions to the scientific community are evidenced by her influential research publications and her role as an executive secretary for significant conferences. These accolades underscore her dedication to advancing biophysics and her impact on both academic and professional circles.

Conclusion

Azadeh Hekmat is a highly deserving candidate for the Research for Best Researcher Award due to her exemplary academic achievements, innovative research, extensive publication record, and recognized contributions to her field. Addressing the areas for improvement could enhance her already impressive profile, potentially leading to even greater advancements in biophysics and related disciplines.

Publication Top Notes

  • Title: A Review on Interaction of Nanomaterials of Group-XIV (G14) Elements of the Periodic Table with Proteins and DNA: Applications in Biotechnology and Pharmacy
    • Authors: Hekmat, A., Haertlé, T., Leblanc, R.M., Khan, R.H., Saboury, A.A.
    • Year: 2024
    • Journal: BioNanoScience
    • Volume: 14
    • Issue: 2
    • Pages: 1978–2003
  • Title: Alteration in the Callogenesis, Tropane Alkaloid Formation, and Gene Expression in Hyoscyamus niger under Clinorotation
    • Authors: Pourhabibian, S., Iranbakhsh, A., Ebadi, M., Hassanpour, H., Hekmat, A.
    • Year: 2024
    • Journal: Protoplasma
    • Volume: 261
    • Issue: 2
    • Pages: 293–302
    • Citations: 2
  • Title: Synthesis of Carbon Quantum Dots from Trigonella foenum-graecum L Seeds and Their Biodistribution in Mice as an Inorganic Isotope Label
    • Authors: Rezaei, M., Hekmat, A., Chamani, J., Sadri, K., Darroudi, M.
    • Year: 2024
    • Journal: Inorganic Chemistry Communications
    • Volume: 160
    • Article Number: 111937
    • Citations: 4
  • Title: Synthesis and Characterization of Zinc Oxide-Chitosan Nanocomposite for Targeted Drug Delivery to the Colon
    • Authors: Ghalee-taki, G.N., Rastegari, A.A., Hekmat, A., Rezaee, M.
    • Year: 2024
    • Journal: BioNanoScience
  • Title: Synergistic Antibacterial Effect of the Pistachio Green Hull Extract-Loaded Porphysome Decorated with 4-Nitroimidazole Against Bacteria
    • Authors: Mahafel, N., Vaezi, Z., Barzegar, M., Hekmat, A., Naderi-Manesh, H.
    • Year: 2024
    • Journal: Journal of Liposome Research
    • Volume: 34
    • Issue: 3
    • Pages: 475–488
  • Title: Grafting of Sinapic Acid onto Glucosamine Nanoparticle as a Potential Therapeutic Drug with Enhanced Anti-Inflammatory Activities in Osteoarthritis Treatment
    • Authors: Tajik, E., Vaezi, Z., Tabarsa, M., Hekmat, A., Naderi-Manesh, H.
    • Year: 2023
    • Journal: International Journal of Biological Macromolecules
    • Volume: 253
    • Article Number: 127454
    • Citations: 3
  • Title: Chromone-Embedded Peptidomimetics and Furopyrimidines as Highly Potent SARS-CoV-2 Infection Inhibitors: Docking and MD Simulation Study
    • Authors: Shakibay Senobari, Z., Masoumian Hosseini, M., Teimouri, M.B., Samarghandian, S., Hekmat, A.
    • Year: 2023
    • Journal: BMC Research Notes
    • Volume: 16
    • Issue: 1
    • Article Number: 224
    • Citations: 6
  • Title: Simulated Microgravity Improved Secondary Metabolism in Physalis alkekengi via Influencing Gene Expression and DNA Methylation in a Light Quality-Dependent Manner
    • Authors: Alani, F., Iranbakhsh, A., Ebadi, M., Hassanpour, H., Hekmat, A.
    • Year: 2023
    • Journal: Acta Physiologiae Plantarum
    • Volume: 45
    • Issue: 11
    • Article Number: 129
  • Title: Superoxide Dismutases Inhibitors
    • Authors: Hekmat, A., Saboury, A.A., Saso, L.
    • Year: 2023
    • Book: Metalloenzymes: From Bench to Bedside
    • Pages: 523–531
  • Title: Antiproliferative Effects of Palm Oil in the Presence of Photobiomodulation Against K562 Cancer Cells
    • Authors: Hekmat, A., Bahar, K.F., Hajebrahimi, Z.
    • Year: 2023
    • Journal: Journal of Oil Palm Research
    • Volume: 35
    • Issue: 3
    • Pages: 426–436

 

Azadeh Hekmat | Biochemical- Biophysics | Best Researcher Award

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