Prof. İlhan Yaylım is a distinguished academic specializing in molecular medicine and biochemistry, with extensive expertise in cancer biology and molecular genetics. He serves as a Professor at Istanbul University’s Aziz Sancar Institute of Experimental Medicine, where he contributes to groundbreaking research in fundamental medical sciences. With over two decades of academic and research experience, Prof. Yaylım has developed a significant body of work exploring the molecular mechanisms underlying various diseases, particularly cancer. He is a dedicated educator, imparting knowledge on cancer biology and molecular genetics through advanced postgraduate and doctoral courses. His extensive publication record, collaborations, and mentorship of graduate students underscore his commitment to advancing scientific inquiry and fostering the next generation of researchers.
Professional Profile
Education
Prof. Yaylım earned his undergraduate degree in Medical Biological Sciences from Istanbul University’s Cerrahpaşa Faculty of Medicine in 1991. He completed his postgraduate studies in Immunology at the Istanbul University Health Sciences Institute in 1995, focusing on purifying immunoglobulins using High-Performance Liquid Chromatography. He obtained his doctorate in Molecular Medicine in 2000 from the same institute, with a dissertation on the kinetic characterization of the CKI enzyme in normal and cancerous lung tissues and its relationship with Myc oncogene polymorphism. His comprehensive academic background has equipped him with a strong foundation in molecular medicine and translational research.
Professional Experience
Prof. Yaylım began his academic career as an Associate Professor at the Aziz Sancar Institute of Experimental Medicine, specializing in molecular medicine, a position he held from 2003 to 2010. Since 2010, he has been serving as a full Professor at the same institution. In addition to teaching and research, he has taken on administrative roles, contributing to the strategic growth of the institute. Prof. Yaylım has designed and delivered numerous postgraduate and doctoral courses, including those focused on cancer biology, molecular genetics, and clinical applications. His career reflects a deep commitment to academic excellence, innovation, and interdisciplinary collaboration.
Research Interests
Prof. Yaylım’s research interests lie at the intersection of medicine, biochemistry, and molecular genetics. He focuses on cancer biology, investigating gene polymorphisms, molecular pathways, and biomarkers associated with various cancers, including lung, breast, and colorectal cancers. His work extends to exploring the cellular and molecular mechanisms of diseases, aiming to identify novel therapeutic targets and diagnostic markers. Prof. Yaylım also has a keen interest in immunogenetics and translational research, aiming to bridge the gap between laboratory findings and clinical applications.
Research Skills
Prof. Yaylım possesses a diverse range of research skills, including advanced molecular biology techniques, such as gene polymorphism analysis, immunoglobulin purification, and enzyme kinetic characterization. He is proficient in utilizing High-Performance Liquid Chromatography (HPLC), molecular genetics tools, and clinical applications of molecular medicine. His expertise in supervising experimental research and mentoring graduate students demonstrates his ability to lead complex projects effectively. Additionally, his collaborative work with students on cancer biomarkers and gene variants reflects his strength in translational research.
Awards and Honors
Prof. Yaylım has received recognition for his contributions to molecular medicine and biochemistry through numerous academic and research accolades. His leadership in guiding groundbreaking studies and mentoring graduate students has solidified his reputation as a thought leader in the field. While specific awards are not listed, his appointment to esteemed positions, such as Professor at Istanbul University’s Aziz Sancar Institute, and his inclusion in international research platforms like ORCID and Publons, highlight his esteemed professional standing and contributions to advancing medical research.
Conclusion
Prof. İlhan Yaylım is a highly qualified researcher and academic with substantial contributions to cancer biology, molecular medicine, and biochemistry. His dedication to mentoring, teaching, and pioneering health sciences research positions him as a strong contender for the Excellence in Research Award. Addressing areas like international collaborations and global publication presence could enhance his candidature further.
Publication Top Notes
- Resveratrol-Loaded Silver Nanoparticles as an Effective Strategy for Targeted Breast Cancer Therapy”
- Authors: Topçu, E., Hepokur, C., Afşin Kariper, İ., Emre Öksüz, K., Yaylim, İ.
- Journal: ChemistrySelect
- Year: 2024
- “IDO1-mediated catabolism of tryptophan in gastric tumors: Its potential role in the axis of histopathology, differentiation and metastasis”
- Authors: Horozoglu, C., Hakan, M.T., Sonmez, D., Akyuz, F., Yaylim, I.
- Journal: Pathology, Research and Practice
- Year: 2024
- “Genetic Investigation of the Trail Mechanism in Diabetic and Non-diabetic Obese Patients”
- Authors: Aksoyer Sezgin, S.B., Durak, S., Celik, F., Yaylim, I., Zeybek, U.
- Journal: Biochemical Genetics
- Year: 2024
- “TRAIL C1595T Variant Critically Alters the Level of sTRAIL in Terms of Histopathological Parameters in Colorectal Cancer”
- Authors: Horozoglu, C., Yildiz, A., Sonmez, D., Arikan, S., Yaylim, I.
- Journal: Indian Journal of Clinical Biochemistry
- Year: 2024
- “Regulation of Nrf2/Keap1 signaling pathway in cancer drug resistance by galectin-1: cellular and molecular implications”
- Authors: Yaylim, İ., Aru, M., Farooqi, A.A., Arese, M., Saso, L.
- Journal: Cancer Drug Resistance
- Year: 2024
- Citations: 2
- “The analysis of Survivin promoter (−31G/C) gene variation in oral squamous cell carcinoma risk and prognosis”
- Authors: Cacına, C., Akgün, A., Kayhan, K.B., Yaylım, İ., Çakmakoğlu, B.
- Journal: Journal of Stomatology, Oral and Maxillofacial Surgery
- Year: 2023
- Citations: 3
- “Investigation of miR221 and miR222 as Biomarkers in Non-small Cell Lung Cancer”
- Authors: Oltulu, Y.M., Coskunpinar, E., Yildiz, P., Karimova, A., Yaylim, I.
- Journal: In Vivo
- Year: 2023
- Citations: 1
- “Plasma Levels of Kynurenine, Soluble OX40 and Mir-138-5p Are Associated With Tumor-infiltrating Lymphocytes in Colorectal Cancer: An Exploratory Study”
- Authors: Zor, D.S., Hakan, M.T., Özgür, E., Gezer, U., Yaylim, I.
- Journal: Anticancer Research
- Year: 2023
- Citations: 6
- “The influence of CASP8 D302H gene variant in colorectal cancer risk and prognosis”
- Authors: Cacina, C., Sürmen, S.T., Arıkan, S., Pençe, S., Yaylım, İ.
- Journal: Turkish Journal of Biochemistry
- Year: 2023
- “lncRNA NORAD, soluble ICAM1 and their correlations may be related to the regulation of the tumor immune microenvironment in laryngeal squamous cell carcinoma (LSCC)”
- Authors: Horozoglu, C., Bal, G., Kabadayı, B., Verim, A., Yaylım, İ.
- Journal: Pathology Research and Practice
- Year: 2023