Alexander Degtyarev | Dynamics Simulation | Excellence in Research

Prof Dr. Alexander Degtyarev | Dynamics Simulation | Excellence in Research

Professor of Saint Petersburg State University, Switzerland.

Alexander Degtyarev is a distinguished Professor at St. Petersburg State University, where he leads the Department of Computer Modeling and Multiprocessor Systems. With a background in hydro-aerodynamics from the Leningrad Shipbuilding Institute, he has made significant contributions to high-performance computing in marine sciences. His research portfolio includes five Russian Foundation for Basic Research grants, multiple EU projects, and over 90 journal publications. Degtyarev is recognized for pioneering work in designing the first vector and Beowulf clusters in Eastern Europe, earning prestigious accolades such as the Bangemann Prize and the “Professor of the Year” award in 2018. He has collaborated with leading global institutions and companies, including Bosh, Siemens, and Huawei, enhancing the practical impact of his research. His innovative contributions are further reflected in his authorship of books and patents, cementing his reputation as a leader in computational fluid dynamics and naval architecture.

Profile
Education

Alexander Degtyarev’s educational journey is rooted in a strong foundation in engineering and computational sciences. He graduated from the Leningrad Shipbuilding Institute in 1985, where he earned a degree in hydro-aerodynamics, equipping him with a deep understanding of fluid dynamics and naval architecture. His passion for advanced computational methods led him to pursue further studies, culminating in a Ph.D. in 1991, where he focused on developing innovative computational models for fluid dynamics. Driven by a desire to push the boundaries of scientific computing, he continued his academic pursuits and achieved a doctoral dissertation in 2005. This advanced research solidified his expertise in high-performance computing systems, particularly in the marine sciences domain. Degtyarev’s educational background, combining engineering principles with computational prowess, has been instrumental in shaping his distinguished career as a leading scientist in computational fluid dynamics and marine engineering.

Professional Experience

Alexander Degtyarev is a seasoned academic and researcher with a distinguished career at St. Petersburg State University, where he currently serves as a Professor and Head of the Department of Computer Modeling and Multiprocessor Systems. He holds a degree in hydro-aerodynamics from the Leningrad Shipbuilding Institute, obtained in 1985, and earned his Ph.D. in 1991, followed by a doctoral dissertation in 2005. Throughout his career, Degtyarev has played a pivotal role in advancing high-performance computing, particularly in the context of marine science and engineering. His leadership has driven the development and implementation of pioneering computational systems, including the world’s first vector cluster and Europe’s first Power and Beowulf clusters. In addition to his academic pursuits, Degtyarev has led numerous consultancy projects with industry giants such as Bosch, Siemens, and Samsung, reflecting his expertise in bridging the gap between theoretical research and practical applications.

Research Interest

Alexander Degtyarev’s research interests lie at the intersection of high-performance computing, computational fluid dynamics, and naval architecture, with a focus on advancing marine science and technology. As a pioneer in the development of multiprocessor systems and vector clusters, he has contributed significantly to the simulation and modeling capabilities essential for marine engineering. His work involves the creation of onboard decision support systems that enhance the operational efficiency and safety of marine vessels. Degtyarev has led and collaborated on numerous international research projects, exploring the application of big data analytics and advanced computing techniques to solve complex problems in fluid dynamics and ship design. His contributions extend to the development of marine virtual testbeds, which leverage high-performance computing infrastructures to simulate real-world maritime scenarios, ultimately improving the design and functionality of marine systems. His research continues to push the boundaries of computational capabilities in the marine sector.

Research Skills

Alexander Degtyarev possesses a robust set of research skills honed through decades of experience in high-performance computing and computational fluid dynamics, with a focus on marine science applications. He is adept at designing and implementing complex computational models, as demonstrated by his pioneering work on the world’s first vector cluster and the Beowulf cluster in Eastern Europe. His expertise extends to the development of onboard decision support systems and marine virtual testbeds, which require sophisticated data analysis and simulation capabilities. Degtyarev’s proficiency in securing and managing large-scale research grants highlights his ability to lead collaborative projects and drive innovation in his field. Additionally, his strong publication record, with over 90 journal articles and multiple patents, underscores his skill in conducting rigorous research and contributing valuable insights to the scientific community. His experience in consultancy with industry giants further reflects his ability to translate research into practical, impactful solutions.

Awards and Recognition

Alexander Degtyarev has garnered significant recognition for his pioneering work in high-performance computing and its applications in marine science. A key member of the team that developed the world’s first vector cluster, the first Power cluster in Europe, and the first Beowulf cluster in Eastern Europe, Degtyarev’s contributions have been instrumental in advancing computational technologies. His work earned the prestigious Bangemann Prize in Information Technology, highlighting the global impact of his research. In 2018, he was honored with the national award “Professor of the Year,” underscoring his leadership in academia and research. His innovations extend to the development of marine virtual testbeds, which have set new benchmarks in computational fluid dynamics and naval architecture. Degtyarev’s patents and publications further demonstrate his commitment to advancing scientific knowledge, making him a highly respected figure in the fields of computational science and marine engineering.

Conclusion

Alexander Degtyarev is a well-qualified candidate for the Research for Best Researcher Award, given his extensive experience, innovative contributions to high-performance computing in marine science, and significant research output. However, to further bolster his candidacy, improving his citation impact and engaging more with the global scientific community through professional memberships and editorial roles could be beneficial. His pioneering work and recognized expertise make him a strong contender for this award.

Publications Top Notes

  1. First-Principles Algorithms for Ship Motion Simulation Based on ARMA and Trochoidal Wave Models
    • Authors: Degtyarev, A., Khramushin, V.
    • Year: 2024
  2. Mathematics as an Engine for Computational Sciences
    • Authors: Bogdanov, A., Degtyarev, A., Mareev, V.
    • Year: 2024
  3. SPD On-Line Filter: Workload Management System and Pilot Agent
    • Authors: Greben, N., Romanychev, L., Oleynik, D., Degtyarev, A.
    • Year: 2024
  4. Methods for Complex Simulators Development for Complex Technical Objects Control
    • Authors: Degtyarev, A., Pylnev, Y., Dolgov, V., Smirnov, V., Tregubov, V.
    • Year: 2024
  5. Real-Time Simulation, Decomposition of Mathematical Models, and Algorithms of Interactive Control and Visualization
    • Authors: Degtyarev, A., Khramushin, V.
    • Year: 2024
  6. Virtual Testbed: Computational Component of Wind Waves – Ship Interaction
    • Authors: Degtyarev, A., Khramushin, V.
    • Year: 2022
  7. A Multilayer Approach to the Security of Blockchain Networks of the Future
    • Authors: Bogdanov, A., Degtyarev, A., Shchegoleva, N., Kiyamov, J., Dik, A.
    • Year: 2022
    • Citations: 2
  8. Solving the Problems of Byzantine Generals Using Blockchain Technology
    • Authors: Bogdanov, A., Degtyarev, A., Shchegoleva, N., Dik, A., Faradzhov, A.
    • Year: 2021
  9. Risk Model of Application of Lifting Methods
    • Authors: Bogdanov, A., Degtyarev, A., Shchegoleva, N., Dik, A., Faradzhov, A.
    • Year: 2021
    • Citations: 2
  10. Increasing the Accuracy of the Diagnosis of Mental Disorders Based on Heterogeneous Distributed Data
    • Authors: Bogdanov, A., Degtyarev, A., Zalutskaya, N., Belavin, S., Khokhryakova, A.
    • Year: 2021

 

Sana Kouba | Intracellular Signalling | Best Researcher Award

Dr. Sana Kouba | Intracellular Signalling | Best Researcher Award

Postdoctoral Researcher of University of Geneva, Switzerland.

Dr. Sana-Salomé Kouba is a postdoctoral researcher at the University of Geneva, specializing in intracellular signaling and cancer research. Her diverse experience includes roles at Penn State College of Medicine and the University of Picardie, where she investigated topics such as the S-acylation of STIM1 splice variants and the role of Orai and TRP channels in cancer progression. Dr. Kouba holds a Ph.D. from the University of Tours, and her research has earned her several awards, including poster accolades at international conferences and travel grants. She is proficient in advanced techniques like calcium imaging, molecular biology, and cell biology, and has made significant contributions to science education through her teaching and creation of instructional materials. Her strong technical skills, combined with her dedication to research and outreach, position her as a notable figure in her field.

Profile
Education

Dr. Sana-Salomé Kouba’s educational journey began with a Bachelor’s degree in Biochemistry from the Holy Spirit University of Kaslik, Lebanon, in 2013. She then pursued a Master’s degree in Pharmacology, Physiopathology, and Neurobiology at the University of Nice Sophia Antipolis, France, graduating in 2015. Building on her foundation, Dr. Kouba completed her doctoral studies at the University of Tours, France, from 2016 to 2020. Her PhD research, conducted within the INSERM U1069 Nutrition Croissance et Cancer (N2C) unit, was supervised by Dr. Marie Potier-Cartereau and Prof. Mohamed Trebak. Her academic background reflects a strong emphasis on biochemistry, pharmacology, and cancer research, equipping her with a robust skill set and deep expertise in her field.

Professional Experience

Dr. Sana-Salomé Kouba is a distinguished researcher currently serving as a Postdoctoral Researcher at the University of Geneva, Switzerland, focusing on intracellular signaling and cancer research under the guidance of Prof. Nicolas Demaurex. Her prior experience includes roles as a Teaching and Research Assistant at the University of Picardie in France, where she investigated cellular and molecular mechanisms in cancer. She also worked as a Research Visiting Scholar at Penn State College of Medicine, studying mitochondrial calcium uniporters in ovarian cancer. Dr. Kouba has held various research positions, including internships at the Institute of Molecular and Cellular Pharmacology and the Laboratory of Molecular Physiomedicine in France, contributing to projects on potassium channels and sodium/proton exchangers. Her broad experience spans molecular biology, biochemistry, and cell biology, reflecting her expertise in advanced scientific techniques and research.

Research Interest

Dr. Sana-Salomé Kouba’s research interests are centered on intracellular signaling and its implications in disease, particularly cancer. She investigates the S-acylation of STIM1 splice variants and its role in skeletal muscle function and cancer, focusing on the modulation of CRAC channels. Her work explores the role of Orai and TRP channels in cancer growth and progression, as well as the mitochondrial calcium uniporter’s influence on ovarian cancer cell migration. Dr. Kouba’s research also delves into the biochemical and pharmacological characterization of ion channels and transporters, including potassium channels and sodium/proton exchangers. Her expertise spans advanced techniques such as calcium imaging, molecular biology, and cell biology, aiming to unravel the molecular mechanisms underlying cancer and other diseases. Her research contributes to a deeper understanding of cellular processes and the development of potential therapeutic targets.

Research Skills

Dr. Sana-Salomé Kouba exhibits a diverse and comprehensive skill set in research that underscores her expertise and versatility. She is proficient in advanced techniques such as calcium imaging, molecular biology (including DNA/RNA extraction, cloning, PCR, and qPCR), and biochemistry methods like immunoprecipitation and cell surface biotinylation. Her expertise extends to cell biology techniques, including cell culture, confocal and TIRF microscopy, immunofluorescence, and proximity ligation assays. Dr. Kouba is also skilled in flow cytometry and has extensive experience with software tools such as Microsoft Office Suite, ImageJ, GraphPad, FlowJo, and Zotero. Her ability to produce and edit educational content, including instructional videos and visual games, highlights her commitment to science communication and education. These skills, combined with her research experience across multiple prestigious institutions, demonstrate her capability to contribute significantly to her field.

Awards and Recognition

Dr. Sana Kouba has garnered notable recognition in her scientific career, reflecting her significant contributions to research and education. In 2023, she received the Poster Award at both the FASEB Calcium and Cell Function Conference in Dublin, Ireland, and the Life Science Switzerland (LS2) Annual Meeting in Lausanne, Switzerland, highlighting her impactful research presentations. Her previous accolades include travel grants for academic conferences, such as the European Calcium Society Meeting in Hamburg, Germany, and the Academic Travel Scholar Program in the United States. These awards and grants underscore Dr. Kouba’s active engagement with the scientific community and her commitment to advancing her field through high-quality research and presentations. Her achievements not only recognize her individual contributions but also emphasize her role in disseminating crucial scientific knowledge and fostering professional development in her areas of expertise.

Conclusion

Sana-Salomé Kouba is a strong candidate for the Research for Best Researcher Award due to her impressive range of research experience, significant contributions to cancer research, teaching accomplishments, and skills in advanced scientific techniques. Her awards and travel grants reflect her active participation and recognition in the scientific community.

Publications Top Notes

  1. S-Acylation of Ca2+ Transport Proteins: Molecular Basis and Functional Consequences
    • Authors: R Néré, S Kouba, A Carreras-Sureda, N Demaurex
    • Year: 2024
    • Citations: 3
  2. S-Acylation of Ca2+ Transport Proteins in Cancer
    • Authors: S Kouba, N Demaurex
    • Year: 2024
  3. Pivotal Role of the ORAI3-STIM2 Complex in the Control of Mitotic Death and Prostate Cancer Cell Cycle Progression
    • Authors: S Kouba, P Buscaglia, M Guéguinou, O Mignen, M Potier-Cartereau
    • Year: 2023
    • Citations: 3
  4. Acid Adaptation Promotes TRPC1 Plasma Membrane Localization Leading to Pancreatic Ductal Adenocarcinoma Cell Proliferation and Migration through Ca2+ Entry and Interaction with PI3K/CaM
    • Authors: J Schnipper, S Kouba, F Hague, H Pedersen, S-F Ouadid-Ahidouch
    • Year: 2022
    • Citations: 3
  5. Crosstalk Between Ca2+ Signaling and Cancer Stemness: The Link to Cisplatin Resistance
    • Authors: S Kouba, F Hague, A Ahidouch, H Ouadid-Ahidouch
    • Year: 2022
    • Citations: 6
  6. The TRPC1 Channel Forms a PI3K/CaM Complex and Regulates Pancreatic Ductal Adenocarcinoma Cell Proliferation in a Ca2+-Independent Manner
    • Authors: J Schnipper, S Kouba, F Hague, H Pedersen, S-F Ouadid-Ahidouch
    • Year: 2022
    • Citations: 3
  7. Data Pertaining to Aberrant Intracellular Calcium Handling During Androgen Deprivation Therapy in Prostate Cancer
    • Authors: D O’Reilly, T Downing, S Kouba, C Vandier, P Buchanan
    • Year: 2022
  8. CaV1.3 Enhanced Store Operated Calcium Promotes Resistance to Androgen Deprivation in Prostate Cancer
    • Authors: D O’Reilly, T Downing, S Kouba, C Vandier, P Buchanan
    • Year: 2022
    • Citations: 9
  9. Orai3 Calcium Channel Regulates Breast Cancer Cell Migration Through Calcium-Dependent and -Independent Mechanisms
    • Authors: M Chamlali, S Kouba, L Rodat-Despoix, A Schwab, H Ouadid-Ahidouch
    • Year: 2021
    • Citations: 14
  10. Synthetic Alkyl-Ether-Lipid Promotes TRPV2 Channel Trafficking Through PI3K/Akt-Girdin Axis in Cancer Cells and Increases Mammary Tumour Volume
    • Authors: M Guéguinou, R Felix, S Marionneau-Lambot, C Vandier, M Potier-Cartereau
    • Year: 2021
    • Citations: 6