Fatemeh Safari | Cancer Therapy | Women Researcher Award

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Assist Prof Dr. Fatemeh Safari | Cancer Therapy | Women Researcher Award

Associate Professor at University of Guilan, Iran

Dr. Fatemeh Safari is an accomplished academic and researcher currently serving as an Associate Professor at the University of Guilan, Iran. She holds a Ph.D. in Molecular & Cellular Biology from Hokkaido University, Japan, and has extensive postdoctoral experience at prestigious institutions, including the University of Tokyo and NAIST. Dr. Safari has made significant contributions to the field of microbiology and cancer research, with numerous publications in reputable journals and books. Her work explores the molecular mechanisms underlying cancer progression and treatment, focusing on the therapeutic potential of stem cell secretomes and natural compounds like green tea extracts. Awarded multiple fellowships, including the JSPS Fellowship and Monbukagakusho Scholarship, she has established herself as a leading researcher. Dr. Safari’s expertise is complemented by her commitment to mentoring students and her active involvement in academic collaborations. Her research continues to impact the scientific community, enhancing our understanding of cancer biology and potential therapies.

Profile

Education

Assistant Professor Dr. Fatemeh Safari holds a Ph.D. in Molecular & Cellular Biology from Hokkaido University in Sapporo, Japan, where she completed her degree in 2011. Prior to her doctoral studies, she earned a Master’s degree in Microbiology from the University of Tehran in 2005, further solidifying her foundational knowledge in the biological sciences. Dr. Safari began her academic journey with a Bachelor’s degree in Biology, obtained from the University of Shahid Beheshti in Tehran, Iran, in 1999. Her diverse educational background encompasses a strong focus on molecular and cellular mechanisms, equipping her with the expertise necessary for her research in cancer biology and regenerative medicine. Dr. Safari’s academic achievements reflect her commitment to advancing scientific knowledge and contributing to the fields of microbiology and molecular biology.

Professional Experience

Prof. Dr. Fatemeh Safari has extensive experience in academia and research. Currently, she serves as an Associate Professor at the University of Guilan, Iran, since September 2022, where she has made significant contributions to the field of Molecular and Cellular Biology. Prior to this role, she was an Assistant Professor at the same institution from September 2016 to 2022. Dr. Safari gained valuable research experience as a Postdoctoral Fellow at prestigious institutions in Japan, including NAIST from 2014 to 2015 and The University of Tokyo from 2012 to 2014. Earlier in her career, she worked as a Research Assistant at the University of Tehran from 2005 to 2007. Throughout her career, Dr. Safari has focused on innovative research in microbiology and cancer biology, publishing extensively in reputable journals and contributing to various collaborative research projects. Her academic journey reflects her dedication to advancing scientific knowledge and mentoring future generations of researchers.

Research Interest

Professor Dr. Fatemeh Safari’s research interests lie at the intersection of molecular and cellular biology, with a particular focus on cancer biology, stem cell therapy, and drug development. Her work delves into understanding the molecular mechanisms underlying cancer progression and the potential therapeutic effects of mesenchymal stem cell (MSC) secretomes on various cancer types, including breast and colon cancers. Dr. Safari’s research also explores the modulation of cellular signaling pathways by natural and synthetic compounds, aiming to develop innovative anti-cancer agents. Her investigations into molecular docking, drug synthesis, and the bioactivity of green tea extracts highlight her commitment to finding novel therapeutic approaches. Additionally, she is involved in the development of advanced methodologies, such as spheroid formation and co-culture systems, to study tumor microenvironments. Dr. Safari’s research is highly interdisciplinary, contributing to the fields of oncology, pharmacology, and biotechnology.

Research Skills

Prof. Dr. Fatemeh Safari possesses a diverse array of research skills that significantly contribute to her expertise in molecular and cellular biology. Her extensive experience in microbiology and cancer research equips her with a robust foundation in experimental design and methodology. Proficient in advanced techniques such as molecular docking, cell culture, and the development of in vitro cancer models, she adeptly investigates cellular signaling pathways and the effects of various compounds on cancer cell behavior. Dr. Safari’s analytical skills are demonstrated through her numerous publications, showcasing her ability to synthesize complex data and draw meaningful conclusions. Additionally, her familiarity with both traditional and innovative approaches in microbiology allows her to explore interdisciplinary research opportunities. As a result, she is not only a proficient researcher but also a valuable mentor to emerging scientists, fostering a collaborative and innovative research environment in her laboratory.

Award and Recognition

Prof. Dr. Fatemeh Safari is a distinguished academic in the field of Molecular & Cellular Biology, recognized for her significant contributions to cancer research. She holds a Ph.D. from Hokkaido University and has garnered prestigious fellowships, including the Monbukagakusho Scholarship and the Japan Society for the Promotion of Science Fellowship. As an Associate Professor at the University of Guilan, she has published over 30 research articles in reputable journals and co-authored several book chapters, focusing on the molecular mechanisms of cancer and the therapeutic potential of stem cell secretomes. Her innovative research has earned her recognition within the academic community, and she actively participates in international conferences, sharing her findings and insights. Prof. Dr. Safari’s dedication to advancing scientific knowledge, coupled with her mentorship of emerging researchers, underscores her impactful role in the scientific community, making her a deserving candidate for the Best Researcher Award.

Conclusion

Professor Dr. Fatemeh Safari is a distinguished academic and researcher in the field of Molecular & Cellular Biology, with significant contributions to cancer research and regenerative medicine. Her extensive educational background, including a Ph.D. from Hokkaido University, complements her impressive publication record, featuring numerous articles in reputable journals. As an Associate Professor at the University of Guilan, she has demonstrated leadership in academia while mentoring students and collaborating on innovative research projects. Dr. Safari’s research focuses on the therapeutic potential of human adipose-derived mesenchymal stem cells (hAMSCs) in cancer treatment, highlighting her commitment to advancing scientific knowledge. Her recognition through prestigious fellowships, such as the JSPS Fellowship, underscores her international standing in the scientific community. With her blend of expertise, experience, and a dedication to research excellence, Professor Dr. Fatemeh Safari is a strong candidate for the Best Researcher Award, embodying the qualities of a leading scholar in her field.

Publication Top Notes
  1. Exploring the dichotomy of the mesenchymal stem cell secretome: Implications for tumor modulation via cell-signaling pathways
    • Authors: Rasouli, M., Alavi, M., D’Angelo, A., Roudi, R., Safari, F.
    • Year: 2024
    • Journal: International Immunopharmacology
    • Volume/Page: 143, 113265
    • Citations: 0
  2. Synthesis, molecular docking study, MD simulation, ADMET, and drug likeness of new thiazolo[3,2-a]pyridine-6,8-dicarbonitrile derivatives as potential anti-diabetic agents
    • Authors: Aghahosseini, F., Bayat, M., Sadeghian, Z., Gheidari, D., Safari, F.
    • Year: 2024
    • Journal: PLoS ONE
    • Volume/Issue/Page: 19(9), e0306973
    • Citations: 0
  3. TCAA-promoted novel approach synthesis and in vitro anti-cancer activity evaluation of spiro[indolo[2,1-b]quinazoline-6,4′-pyrano[2,3-c]pyrazole]-5′-carboxamides
    • Authors: Sadeghian, Z., Bayat, M., Eskandari, M., Safari, F.
    • Year: 2024
    • Journal: Results in Chemistry
    • Volume/Page: 9, 101636
    • Citations: 1
  4. The suppression of cell motility through the reduction of FAK activity and expression of cell adhesion proteins by hAMSCs secretome in MDA-MB-231 breast cancer cells
    • Authors: Safari, F., Bararpour, S., Omidi Chomachaei, F.
    • Year: 2024
    • Journal: Investigational New Drugs
    • Volume/Issue/Page: 42(3), pp. 272–280
    • Citations: 1
  5. Regulation of Cellular-Signaling Pathways by Mammalian Proteins Containing Bacterial EPIYA or EPIYA-Like Motifs Predicted to be Phosphorylated
    • Authors: Rasouli, M., Safari, F., Sobhani, N., Alavi, M., Roudi, R.
    • Year: 2024
    • Journal: DNA and Cell Biology
    • Volume/Issue/Page: 43(2), pp. 74–84
    • Citations: 1
  6. IRTKS Elevation in Patients with Colon Cancer and the Curative Influences of Hamsc Secretome on Polarity and Invasion of HT-29 Colon Cancer Cells
    • Authors: Khodabandeh, A., Safari, F., Ebadi Zavieh, S., Mirzanejad, L.
    • Year: 2024
    • Journal: Regenerative Engineering and Translational Medicine
    • Citations: 0
  7. Harnessing Nanotechnology for Idarubicin Delivery in Cancer Therapy: Current Approaches and Future Perspectives
    • Authors: Safari, F., Jalalian, Y., Abdouss, H., Fathi-Karkan, S., Pandey, S.
    • Year: 2024
    • Journal: BioNanoScience
    • Citations: 2
  8. Synthesis, Molecular Docking, and Biological Evaluation of Pyridin-3-yl-Pyrimidin-2-yl-Triazole Derivatives as Anti-cancer Agents
    • Authors: Firoozpour, L., Moghimi, S., Fallah Barzegar, M.H., Safari, F., Foroumadi, A.
    • Year: 2024
    • Journal: Polycyclic Aromatic Compounds
    • Volume/Issue/Page: 44(3), pp. 2062–2076
    • Citations: 1
  9. Synthesis and Biological Evaluation of 12-Aryl-11-hydroxy-5,6-dihydropyrrolo[2″,1″:3′,4′]pyrazino[1′,2′:1,5]pyrrolo[2,3-d]pyridazine-8(9H)-one Derivatives as Potential Cytotoxic Agents
    • Authors: Barghi Lish, A., Foroumadi, A., Kolvari, E., Safari, F.
    • Year: 2023
    • Journal: ACS Omega
    • Volume/Issue/Page: 8(45), pp. 42212–42224
    • Citations: 1
  10. Evaluation of SgK269 expression in colon cancer patients and the effects of hAMSCs secretome on tumor invasion through SgK269/c-Src/p-P130Cas/p-Paxillin/p-ERK1/2 signaling pathway in HT-29 colon cancer cells
    • Authors: Safari, F., Ansari Dogaheh, F., Dadashi, H.
    • Year: 2023
    • Journal: 3 Biotech
    • Volume/Issue/Page: 13(11), 346
    • Citations: 1