James Carter | Molecular Biology | Best Researcher Award

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Dr. James Carter | Molecular Biology | Best Researcher Award

Assistant Professor at Georgia Southern University, United States

Dr. James R. Carter is an accomplished scientist and educator with a robust academic and professional background in biochemistry and molecular biology. Currently serving as an Assistant Professor in the Department of Chemistry & Biochemistry at Georgia Southern University, Dr. Carter has made significant contributions to the fields of viral pathogenesis, antiviral development, and nanoparticle-based drug delivery systems. His career has spanned academia and industry, where he has spearheaded groundbreaking research and innovation. Dr. Carter has successfully mentored numerous graduate and undergraduate students, contributing to their academic and professional growth. His dedication to teaching, research, and service underscores his commitment to advancing scientific knowledge and fostering the next generation of scientists.

Professional Profile

Education

Dr. Carter earned his PhD in Molecular and Cellular Biochemistry from the University of Kentucky in 2007. His dissertation focused on the fusion proteins of Hendra virus, an emerging paramyxovirus, contributing valuable insights into viral protein functionality. Prior to this, he completed a Bachelor of Science in Biochemistry at Plattsburgh State University in 2000, where he developed foundational skills in biochemistry, microbiology, and genetics. This strong educational foundation has been instrumental in his ability to conduct and lead advanced research in biochemistry and virology.

Professional Experience

Dr. Carter’s professional journey includes diverse roles in academia and industry. Since 2019, he has served as an Assistant Professor at Georgia Southern University, leading research on flavivirus pathogenesis, antiviral development, and nanoparticle-based drug delivery systems. Previously, he worked as a Senior Scientist at ViroCure USA, where he explored oncolytic viruses for cancer therapeutics. At Indiana University School of Medicine and the University of Notre Dame, he contributed to groundbreaking research on mosquito-borne viruses and matrix protein functionality in filoviruses. His career reflects a commitment to impactful, interdisciplinary research.

Research Interests

Dr. Carter’s research interests lie at the intersection of viral pathogenesis, antiviral therapies, and advanced drug delivery systems. His work focuses on developing innovative approaches to detect, target, and treat mosquito-borne viruses and emerging pathogens. He is particularly interested in using nanoparticles to enhance drug delivery, offering targeted and efficient solutions for combating viral infections. His research combines molecular biology, biochemistry, and nanotechnology to address pressing public health challenges.

Research Skills

Dr. Carter possesses a wide array of research skills, including advanced molecular biology techniques, nanoparticle synthesis, and viral detection methodologies. He has demonstrated expertise in site-directed mutagenesis, protein folding analysis, and drug delivery system design. Additionally, his experience in grant writing, patent preparation, and regulatory compliance showcases his ability to translate scientific discoveries into practical applications. His skill set is further complemented by his ability to mentor and lead diverse research teams effectively.

Awards and Honors

Dr. Carter has received numerous accolades for his contributions to science and education. These include the ACS Sci-Mix Abstract Selection at the ACS National Meeting, travel awards from the American Society for Virology, and recognition for his teaching and mentoring excellence. His patented innovations in DNAzyme-nanoparticle conjugates further highlight his contributions to cutting-edge research. These achievements underscore his standing as a leader in his field.

Conclusion

Dr. James R. Carter’s extensive academic and professional achievements make him a distinguished candidate for the Best Researcher Award. His innovative research, commitment to education, and dedication to advancing science have had a lasting impact on his field and beyond. While there is room for further accomplishments, particularly in grant acquisition and publication impact, his current contributions firmly establish him as a leading figure in biochemistry and molecular biology.

Publication Top Notes

  1. Application of mPEG-PCL-mPEG Micelles for Anti-Zika Ribavirin Delivery
    • Authors: Blahove, M.R.; Saviskas, J.A.; Rodriguez, J.; Culmer, J.A.; Carter, J.R.
    • Year: 2024
  2. Flavivirus persistence in wildlife populations
    • Authors: Blahove, M.R.; Carter, J.R.
    • Year: 2021
    • Citations: 8
  3. Suppression of the arboviruses dengue and chikungunya using a dual-acting group-I intron coupled with conditional expression of the Bax C-terminal domain
    • Authors: Carter, J.R.; Taylor, S.; Fraser, T.S.; Dawson, J.L.; Fraser, M.J.
    • Year: 2015
    • Citations: 14
  4. Trans-splicing group I intron targeting hepatitis C virus IRES mediates cell death upon viral infection in Huh7.5 cells
    • Authors: Nawtaisong, P.; Fraser, M.E.; Carter, J.R.; Fraser, M.J.
    • Year: 2015
    • Citations: 6
  5. Effective suppression of Dengue virus using a novel group-I intron that induces apoptotic cell death upon infection through conditional expression of the Bax C-terminal domain
    • Authors: Carter, J.R.; Keith, J.H.; Fraser, T.S.; Higgs, S.; Fraser, M.J.
    • Year: 2014
    • Citations: 20
  6. Design and analysis of hammerhead ribozyme activity against an artificial gene target
    • Authors: Carter, J.R.; Nawtaisong, P.; Balaraman, V.; Fraser Jr., M.J.
    • Year: 2014
  7. A novel dengue virus detection method that couples DNAzyme and gold nanoparticle approaches
    • Authors: Carter, J.R.; Balaraman, V.; Kucharski, C.A.; Fraser, T.S.; Fraser, M.J.
    • Year: 2013
    • Citations: 33
  8. Targeting of highly conserved Dengue virus sequences with anti-Dengue virus trans-splicing group I introns
    • Authors: Carter, J.R.; Keith, J.H.; Barde, P.V.; Fraser, T.S.; Fraser Jr, M.J.
    • Year: 2010
    • Citations: 29
  9. Examining the relative activity of several dicistrovirus intergenic internal ribosome entry site elements in uninfected insect and mammalian cell lines
    • Authors: Carter, J.R.; Fraser, T.S.; Fraser Jr., M.J.
    • Year: 2008
    • Citations: 14

 

Pi-Wan Cheng | Molecular Biology | Best Researcher Award

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Prof. Dr. Pi-Wan Cheng | Molecular Biology | Best Researcher Award

Professor at University of Nebraska Medical Center, United States

Dr. Pi Wan Cheng is a distinguished biochemist and molecular biologist with over four decades of experience in research and academia. He currently holds a professorship at the University of Nebraska Medical Center (UNMC) and has contributed significantly to the field of glycobiology. Dr. Cheng has made pivotal advancements in understanding glycan biosynthesis and its role in health, diseases, and cancer. His work, which bridges basic and translational research, is supported by multiple research grants and patents. He has also been an active member of several professional organizations, underscoring his influence in the scientific community. Dr. Cheng’s research focuses on how glycosylation affects immune responses and cancer progression, with a special emphasis on the development of Siglec-7-based therapies for pancreatic cancer.

Professional Profile

Education:

Dr. Pi Wan Cheng obtained his Ph.D. in Biochemistry from Case Western Reserve University, Cleveland, Ohio, in 1975. Prior to that, he earned his M.S. in Biochemistry from National Taiwan University in 1968, following his B.S. in Agricultural Chemistry from the same institution in 1965. Throughout his educational journey, Dr. Cheng worked under the mentorship of prominent scientists such as Dr. Don M. Carlson and Dr. Kuo Huang Ling, which shaped his academic and professional growth in biochemistry and molecular biology.

Professional Experience:

Dr. Cheng’s career spans numerous prestigious academic institutions. He has held faculty positions at Case Western Reserve University, the University of North Carolina, and UNMC. At UNMC, he has been a professor in the Department of Biochemistry and Molecular Biology since 1995, where he was granted tenure in 1997. He also served as a research chemist at the Veterans Affairs Nebraska Western Iowa Health Care System from 2011 to 2017. His role at UNMC also includes courtesy appointments in the College of Pharmacy and the Eppley Institute for Cancer Research, where he has fostered collaborations and contributed to the institution’s research landscape.

Research Interest:

Dr. Cheng’s primary research interest lies in glycobiology, specifically the mechanisms of glycan biosynthesis and its impact on health and disease. His work focuses on understanding how glycans, particularly sialylated O-glycans, influence immune responses and contribute to the progression of diseases such as cancer. He investigates how specific glycans, induced by factors like interleukin-6 and alcohol, can protect cancer cells from immune surveillance and promote tumor growth. His innovative research is also exploring therapies targeting Siglec-7 for pancreatic cancer treatment, with potential applications in immunotherapy and cancer prevention.

Research Skills:

Dr. Cheng possesses a comprehensive skill set in biochemistry, molecular biology, and glycobiology. He is skilled in techniques related to protein biochemistry, glycan analysis, immunology, and cancer research. His expertise includes the development of molecular models to understand glycan interactions with immune cells, as well as employing various biochemical assays to assess glycan expression in disease states. Dr. Cheng’s proficiency extends to experimental design, grant writing, and leading interdisciplinary research teams. He has also contributed to the field through patents, underscoring his ability to translate fundamental discoveries into real-world applications.

Awards and Honors:

Throughout his career, Dr. Cheng has received numerous accolades for his groundbreaking research in glycobiology. His work has been supported by prestigious grants, including those from the Nebraska Department of Health and Human Services, where he has led multiple research projects related to cancer and immune function. He holds patents in biologically active molecule delivery, reflecting his innovative contributions to science. Dr. Cheng is a lifetime member of the Society for Glycobiology and the Society of Chinese Bioscientists in America, and he has been recognized for his service to the scientific community through various professional society memberships and community volunteer work.

Conclusion:

Dr. Pi Wan Cheng is a highly qualified candidate for the Best Researcher Award, with a distinguished career marked by significant research contributions in glycobiology, a track record of continuous funding, and active involvement in the scientific community. His innovative research, particularly in cancer immunology and glycosylation, holds great promise for medical advancements. While there is room for further interdisciplinary collaboration and publication visibility, his foundational work in glycobiology makes him a deserving nominee for this prestigious award.

Publication Top Notes

  1. Markers of malignant prostate cancer cells: Golgi localization of α-mannosidase 1A at GM130-GRASP65 site and appearance of high mannose N-glycans on cell surface
    • Authors: Cheng, P.-W., Davidson, S., Bhat, G.
    • Year: 2020
    • Citations: 12
  2. Inhibitory activity of salivary glycoproteins on phytohemagglutins (PHA): Possible molecules to enhance nutritional quality of red kidney beans
    • Authors: Chachadi, V.B., Nayanegali, T.R., Pujari, B.G., Inamdar, S.R., Cheng, P.-W.
    • Year: 2020
    • Citations: 3
  3. p66Shc protein through a redox mechanism enhances the progression of prostate cancer cells towards castration-resistance
    • Authors: Miller, D.R., Ingersoll, M.A., Chatterjee, A., Oberley-Deegan, R.E., Lin, M.-F.
    • Year: 2019
    • Citations: 18
  4. Shifted Golgi targeting of glycosyltransferases and α-mannosidase IA from giantin to GM130-GRASP65 results in formation of high mannose N-glycans in aggressive prostate cancer cells
    • Authors: Bhat, G., Hothpet, V.-R., Lin, M.-F., Cheng, P.-W.
    • Year: 2017
    • Citations: 18
  5. The role of Rab6a and phosphorylation of non-muscle myosin IIA tailpiece in alcohol-induced Golgi disorganization
    • Authors: Petrosyan, A., Casey, C.A., Cheng, P.-W.
    • Year: 2016
    • Citations: 22
  6. Downregulation of the small GTPase SAR1A: A key event underlying alcohol-induced Golgi fragmentation in hepatocytes
    • Authors: Petrosyan, A., Cheng, P.-W., Clemens, D.L., Casey, C.A.
    • Year: 2015
    • Citations: 20
  7. Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands
    • Authors: Chachadi, V.B., Bhat, G., Cheng, P.-W.
    • Year: 2015
    • Citations: 15
  8. Keratin 1 plays a critical role in Golgi localization of core 2 N-acetylglucosaminyltransferase M via interaction with its cytoplasmic tail
    • Authors: Petrosyan, A., Ali, M.F., Cheng, P.-W.
    • Year: 2015
    • Citations: 20
  9. Restoration of compact Golgi morphology in advanced prostate cancer enhances susceptibility to galectin-1-induced apoptosis by modifying mucin O-glycan synthesis
    • Authors: Petrosyan, A., Holzapfel, M.S., Muirhead, D.E., Cheng, P.-W.
    • Year: 2014
    • Citations: 64
  10. Golgi fragmentation induced by heat shock or inhibition of heat shock proteins is mediated by non-muscle myosin IIA via its interaction with glycosyltransferases
    • Authors: Petrosyan, A., Cheng, P.-W.
    • Year: 2014
    • Citations: 24

 

Xiumin Wang | Molecular Biology | Women Researcher Award

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Prof. Dr. Xiumin Wang | Molecular Biology | Women Researcher Award

Researcher at Feed Research Institute, Chinese Academy of Agricultural Sciences, China

Dr. Wang Xiumin is a distinguished researcher currently serving at the Institute of Feed Research, Chinese Academy of Agricultural Sciences (CAAS). With a profound academic background and extensive research experience in the field of plant pathology and microbial resistance, Dr. Wang has become a leading figure in her field. Over her career, she has focused on microbial resistance, antibacterial peptides, and the development of therapeutic strategies to combat infectious diseases, especially those involving multi-drug resistant pathogens. Dr. Wang’s work has been instrumental in bridging the gap between fundamental microbiology and applied agricultural practices, contributing to the development of feed-related solutions and sustainable agricultural practices. Her research is widely recognized through numerous publications in prestigious scientific journals, where she has co-authored over 80 papers.

Professional Profile

Education:

Dr. Wang Xiumin obtained her Ph.D. in Plant Pathology from Northwest Agriculture & Forestry University in 2006, after completing her Master’s and Bachelor’s degrees at the same institution in 2003 and 2000, respectively. Her academic training equipped her with in-depth knowledge in plant protection and pathology, laying a strong foundation for her career in agricultural sciences and microbiology. Her academic journey enabled her to focus on plant diseases, microbiology, and biotechnology, advancing her research in combating bacterial resistance in agricultural systems.

Professional Experience:

Dr. Wang Xiumin has accumulated extensive professional experience across various prestigious institutions. From 2006 to 2009, she worked as a Postdoctoral Fellow at Beijing Forestry University, engaging in critical research in plant pathology. Between 2009 and 2013, she served as an Assistant Researcher at the Feed Research Institute of CAAS. Since 2013, she has held the position of Associate Researcher at the same institute. In 2019-2020, she visited the School of Chemistry and Molecular Biosciences at the University of Queensland, further enhancing her expertise in molecular biosciences and plant pathology. Throughout her career, Dr. Wang has continually advanced her research while mentoring emerging scientists in her field.

Research Interests:

Dr. Wang’s research interests lie at the intersection of microbial resistance, plant pathology, and feed-related research. Her work primarily focuses on antibacterial peptides, microbial resistance mechanisms, and the development of therapeutic proteins and peptides. She has also contributed to studies on food safety, including the detoxification of mycotoxins, and has explored the therapeutic potential of marine peptides for bacterial infections. Dr. Wang’s research in microbial resistance and peptide-based therapeutics is crucial for advancing sustainable agricultural and clinical practices, particularly in the context of combating drug-resistant pathogens in both animals and humans.

Research Skills:

Dr. Wang Xiumin is highly skilled in a variety of research techniques including molecular biology, microbiology, and biotechnology. She has experience in the design and application of antibacterial peptides, the isolation and characterization of bioactive compounds, and the assessment of microbial resistance mechanisms. Her expertise also extends to advanced techniques in molecular cloning, protein expression, and peptide synthesis. Additionally, Dr. Wang is adept at using in vitro and in vivo models to study the effects of therapeutic peptides and other compounds on microbial infections. Her diverse skill set has been pivotal in advancing her research projects and making significant contributions to agricultural and health sciences.

Awards and Honors:

Dr. Wang Xiumin has received several accolades for her outstanding contributions to the field of plant pathology and microbiology. She has been recognized for her innovative research in microbial resistance and peptide-based therapeutics, receiving awards from various scientific and agricultural bodies in China. Her significant publications in high-impact journals such as Science of the Total Environment, Journal of Medicinal Chemistry, and Food Chemistry have cemented her reputation as a leading researcher in her field. Additionally, her collaborative work with international research institutes has earned her several fellowships, including her research visit to the University of Queensland, further acknowledging her impact on global agricultural science and medical microbiology.

Conclusion

Dr. Wang Xiumin demonstrates a strong and well-rounded research profile, with impressive publications and a proven ability to address complex issues in plant pathology and antimicrobial resistance. His work is highly relevant and impactful in agricultural and biomedical fields. His contributions place him as a strong candidate for the Excellence in Research Award. Expanding his industry collaborations and mentoring roles would elevate his profile further, making him an even more influential figure in his field.

Publication Top Notes

  1. Application of Lactobacillus plantarum and Pediococcus lactis on Lipid Metabolism, Anti-Inflammatory, and Fecal Microbiota in Cats
    • Authors: Shukun Liang, Xinshu Gu, Jintao Sun, Xiumin Wang, Hui Tao, Zhenlong Wang, Yougang Zhong, Jinquan Wang, Bing Han
    • Year: 2024
    • DOI: 10.3390/microorganisms12122446
  2. Application of Network Pharmacology, Molecular Docking, and In Vitro Experimental Evaluation to Decipher the Anti-Inflammatory Mechanisms of Cirsium japonicum
    • Authors: Jiaxue Wang, Hui Tao, Zhenlong Wang, Wei An, Ya Zhao, Bing Han, Jinquan Wang, Xiuzhu Sun, Xiumin Wang
    • Year: 2024
    • DOI: 10.3390/app14219687
  3. Simultaneous Degradation of AFB1 and ZEN by CotA Laccase from Bacillus subtilis ZJ-2019-1 in the Mediator-Assisted or Immobilization System
    • Authors: Boquan Gao, Wei An, Jianwen Wu, Xiumin Wang, Bing Han, Hui Tao, Jie Liu, Zhenlong Wang, Jinquan Wang
    • Year: 2024
    • DOI: 10.3390/toxins16100445
  4. Allergies to Allergens from Cats and Dogs: A Review and Update on Sources, Pathogenesis, and Strategies
    • Authors: Wei An, Ting Li, Xinya Tian, Xiaoxin Fu, Chunxiao Li, Zhenlong Wang, Jinquan Wang, Xiumin Wang
    • Year: 2024
    • DOI: 10.3390/ijms251910520
  5. Bacillus subtilis Simultaneously Detoxified Aflatoxin B1 and Zearalenone
    • Authors: Jianwen Wu, Zhenlong Wang, Wei An, Boquan Gao, Chunxiao Li, Bing Han, Hui Tao, Jinquan Wang, Xiumin Wang, Huanrong Li
    • Year: 2024
    • DOI: 10.3390/app14041589
  6. The Effect of Lactobacillus plantarum on the Fecal Microbiota, Short Chain Fatty Acids, Odorous Substances, and Blood Biochemical Indices of Cats
    • Authors: Bing Han, Shukun Liang, Jintao Sun, Hui Tao, Zhenlong Wang, Baosheng Liu, Xiumin Wang, Jie Liu, Jinquan Wang
    • Year: 2024
    • DOI: 10.3390/microorganisms12010091
  7. Comparison Study of Two Fumonisin-Degrading Enzymes for Detoxification in Piglets
    • Authors: Zhenlong Wang, Zonghao Lv, Tibor Czabany, Veronika Nagl, Rudolf Krska, Xiumin Wang, Bing Han, Hui Tao, Jie Liu, Jinquan Wang
    • Year: 2023
    • DOI: 10.3390/toxins16010003
  8. The Effect of Duck Bile Acid Extract on the Fecal Microbiota, Short Chain Fatty Acids, Fat Digestibility and Blood Biochemical Indices in Cats
    • Authors: Bing Han, Peng Zhao, Shukun Liang, Zhenlong Wang, Hui Tao, Xiumin Wang, Jie Liu, Jinquan Wang
    • Year: 2023
    • DOI: 10.3390/app13179713
  9. A Screening Model of Antibacterial Agents Based on Escherichia coli Cell-Division Protein
    • Authors: Qiuyu Fan, Jianwen Wu, Bolin Xi, Chunxiao Li, Xiumin Wang, Huanrong Li
    • Year: 2023
    • DOI: 10.3390/app13074493
  10. Mini-Review: Antibiotic-Resistant Escherichia coli from Farm Animal-Associated Sources
    • Authors: ChunMing Xu, Lingqiang Kong, Yonghong Liao, Yuan Tian, Qi Wu, Haosi Liu, Xiumin Wang
    • Year: 2022
    • DOI: 10.3390/antibiotics11111535

 

Sukhes Mukherjee | Molecular Biology | Outstanding Scientist Award

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Dr. Sukhes Mukherjee | Molecular Biology | Outstanding Scientist Award

Additional Professor at All India Institute Of Medical Sciences Bhopal, India

Dr. Sukhes Mukherjee is a distinguished academic and researcher in the field of biochemistry, with a focus on clinical biochemistry and molecular biology. He currently holds the position of Additional Professor at the All India Institute of Medical Sciences (AIIMS), Bhopal, India. Dr. Mukherjee has built an impressive career over the past 16 years, with substantial contributions to research and education. His work has been widely recognized, earning him numerous awards and honors. He is also known for his leadership in teaching and mentoring students, particularly at the postgraduate level. Dr. Mukherjee’s research focuses on advancing molecular techniques in biochemistry, with an emphasis on health diagnostics and disease management. He has authored over 80 peer-reviewed papers and frequently contributes to conferences and seminars both nationally and internationally.

Professional Profile

Education

Dr. Mukherjee’s educational journey is anchored in biochemistry and molecular biology. He completed his undergraduate and postgraduate education in India, earning a Master’s degree in Medical Biochemistry, followed by a Ph.D. in Biochemistry. His academic training has provided him with a strong foundation in both theoretical knowledge and hands-on laboratory skills. Dr. Mukherjee’s education is complemented by postdoctoral research experiences that have enriched his expertise in clinical biochemistry and molecular diagnostics. He has actively engaged in interdisciplinary training programs and research initiatives, which have shaped his current position as a thought leader in the field.

Professional Experience

Dr. Mukherjee’s professional experience spans more than 16 years, during which he has worked at various prestigious institutions, most notably at AIIMS, Bhopal. In his current role, he is responsible for overseeing clinical biochemistry research, teaching, and administration. Dr. Mukherjee has taught a wide range of courses, from basic biochemistry to advanced molecular biology, guiding both undergraduate and postgraduate students. Additionally, he has served on various academic and research committees, contributing to the development of new curricula and research protocols. His career also includes serving as a mentor to numerous graduate students and postdoctoral researchers, helping them advance their scientific careers.

Research Interests

Dr. Mukherjee’s primary research interests lie in the fields of clinical biochemistry, molecular biology, and health diagnostics. His work focuses on understanding the molecular mechanisms of disease, with particular attention to neurochemistry and biochemical pathways in neurological disorders. He is involved in exploring novel diagnostic biomarkers and therapies to improve patient care. Dr. Mukherjee’s research also covers the application of cutting-edge molecular biology techniques to better understand human health and disease at the cellular and biochemical levels. His interdisciplinary approach includes collaborations with clinicians and other researchers to bridge the gap between benchside research and clinical applications.

Research Skills

Dr. Mukherjee is highly skilled in a range of laboratory techniques and methodologies that are integral to biochemistry and molecular biology. These include protein chemistry, molecular cloning, enzyme assays, and biochemical profiling. He is proficient in various advanced diagnostic techniques, such as mass spectrometry and PCR-based methods, that are essential in clinical research. Dr. Mukherjee also has extensive experience in bioinformatics and data analysis, utilizing computational tools to interpret complex biological data. His research skills are complemented by his ability to manage large-scale research projects and collaborate effectively with multidisciplinary teams.

Awards and Honors

Dr. Mukherjee’s contributions to biochemistry and molecular biology have been recognized through numerous awards and honors. Notably, he received the Best Paper Award from the Association of Clinical Biochemists of India in 2008. He has been a recipient of various travel fellowships to attend and present at international conferences, including those in the US and South Korea. Dr. Mukherjee is a Fellow of the Linnean Society of London, reflecting his international stature in the scientific community. His work continues to attract recognition, both in India and globally, for its impact on advancing clinical biochemistry and molecular diagnostics.

Conclusion

Dr. Sukhes Mukherjee is undoubtedly a highly deserving candidate for the Best Researcher Award, with an impressive record of research contributions, academic excellence, and professional recognition. His extensive research, leadership, and dedication to advancing the field of clinical biochemistry set him apart as a pioneer in his field. With a bit more focus on interdisciplinary research and mentorship, Dr. Mukherjee could have an even more profound influence on both the scientific community and society at large. This nomination reflects his exemplary contributions and positions him as a role model for future researchers in the field.

Publication Top Notes

  1. Alcoholism and its effects on the central nervous system
    Authors: S Mukherjee
    Journal: Current Neurovascular Research 10 (3), 256-262
    Year: 2013
    Citations: 138
  2. Consequences of alcohol consumption on neurotransmitters-an overview
    Authors: S Mukherjee, SK Das, K Vaidyanathan, DM Vasudevan
    Journal: Current Neurovascular Research 5 (4), 266-272
    Year: 2008
    Citations: 86
  3. Evaluation of blood oxidative stress‐related parameters in alcoholic liver disease and non‐alcoholic fatty liver disease
    Authors: SK Das, V Balakrishnan, S Mukherjee, DM Vasudevan
    Journal: Scandinavian Journal of Clinical and Laboratory Investigation 68 (4), 323-334
    Year: 2008
    Citations: 81
  4. Oxidative stress is the primary event: effects of ethanol consumption in brain
    Authors: SK Das, KR Hiran, S Mukherjee, DM Vasudevan
    Journal: Indian Journal of Clinical Biochemistry 22, 99-104
    Year: 2007
    Citations: 77
  5. Comparison of haematological parameters in patients with non-alcoholic fatty liver disease and alcoholic liver
    Authors: SK Das, S Mukherjee, DM Vasudevan, V Balakrishnan
    Journal: Singapore Med J 52 (3), 175-181
    Year: 2011
    Citations: 73
  6. Medicinal properties of milk thistle with special reference to silymarin–an overview
    Authors: SK Das, S Mukherjee, DM Vasudevan
    Publisher: CSIR
    Year: 2008
    Citations: 70
  7. Evolving interplay between dietary polyphenols and gut microbiota—an emerging importance in healthcare
    Authors: SK Ray, S Mukherjee
    Journal: Frontiers in Nutrition 8, 634944
    Year: 2021
    Citations: 68
  8. Biochemical and immunological basis of silymarin effect, a milk thistle (Silybum marianum) against ethanol-induced oxidative damage
    Authors: SK Das, S Mukherjee
    Journal: Toxicology Mechanisms and Methods 22 (5), 409-413
    Year: 2012
    Citations: 63
  9. Protective effect of resveratrol and vitamin E against ethanol-induced oxidative damage in mice: biochemical and immunological basis
    Authors: SK Das, S Mukherjee, G Gupta, DN Rao, DM Vasudevan
    Publisher: CSIR
    Year: 2010
    Citations: 55
  10. Effects of chronic ethanol exposure on renal function tests and oxidative stress in kidney
    Authors: SK Das, S Varadhan, L Dhanya, S Mukherjee, DM Vasudevan
    Journal: Indian Journal of Clinical Biochemistry 23, 341-344
    Year: 2008
    Citations: 49

 

Lian-Wang Guo | Genetics and Molecular Biology| Best Researcher Award

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Dr. Lian-Wang Guo | Genetics and Molecular Biology| Best Researcher Award

Professor at University of Virginia, United States

Dr. Lian-Wang Guo is a Professor of Biomedical Sciences at the University of Virginia with over 20 years of experience in vascular biology and biochemistry. His research primarily focuses on the role of epigenetic modulators in vascular diseases, particularly neointima-associated restenosis. He has been continuously funded by the NIH since 2012 and has published 48 peer-reviewed papers in the past six years, while also filing six patent applications. Dr. Guo’s innovative work includes developing biomimetic nanoplatforms for targeted drug delivery, which are currently in advanced trials for treating vascular conditions. His research integrates basic science with clinical applications, notably through collaboration with Dr. Craig Kent. Dr. Guo is recognized for his significant contributions to vascular epigenetics and has created a rigorous and inclusive training environment for young researchers. His work holds promise for advancing therapeutic strategies and improving clinical outcomes for vascular diseases.

Professional Profile

Education

Dr. Lian-Wang Guo’s educational background is rooted in biology and advanced plant physiology, providing a strong foundation for his extensive research career. He earned his Bachelor of Science degree in Biology from Xinjiang University in China in 1989, followed by a Master of Science in Plant Physiology from the prestigious Chinese Academy of Sciences in 1992. He continued his studies there, earning a Ph.D. in Plant Physiology and Biochemistry in 1995. Driven by a passion for genetics and biochemistry, Dr. Guo completed a postdoctoral fellowship at The Hebrew University of Jerusalem in 1998, where he broadened his research expertise in molecular biology. His educational journey reflects a commitment to understanding complex biological processes, which he has successfully applied to his pioneering work in vascular biology and epigenetics. Dr. Guo’s solid academic training has been instrumental in his innovative research contributions and leadership in biomedical sciences.

Professional Experience

Dr. Lian-Wang Guo is a tenured Professor of Biomedical Sciences at the University of Virginia, specializing in vascular biology and epigenetics. With over 20 years of research experience, Dr. Guo has developed an expertise in chromatin modulators and their role in vascular diseases, particularly in neointima-associated restenosis. He has been continuously funded by the NIH since 2012, and his prolific contributions include 48 peer-reviewed publications and multiple patents, reflecting his leadership in vascular epigenetics research. His laboratory employs advanced molecular techniques such as ChIPseq, RNAseq, bioinformatics, and innovative nanoplatforms for targeted drug delivery. Dr. Guo has also successfully fostered clinical collaborations, including the development of therapeutic interventions currently undergoing large animal trials, with preparations for human studies. A dedicated mentor, he has cultivated a rigorous training environment for students and fellows, helping them transition into independent research careers. His research has garnered numerous awards and recognition from prominent scientific organizations.

Research Interests

Lian-Wang Guo’s research interests center around the intersection of vascular biology, epigenetics, and targeted drug delivery. As a professor of Biomedical Sciences, his work focuses on understanding the role of chromatin modulators, such as EZH2, DOT1L, and BRD4, in vascular diseases, particularly neointima-associated restenosis. By uncovering how these epigenetic regulators influence disease-specific gene expression, he aims to develop precise therapeutic strategies that mitigate pathological vascular remodeling while preserving normal cellular functions. Dr. Guo is also deeply involved in translational research, advancing the use of biomimetic nanoplatforms for targeted, localized drug delivery. His lab has developed innovative nanotechnologies to deliver therapeutic agents to disease sites, aiming to enhance efficacy and minimize side effects. A key element of his research is the integration of basic science discoveries with clinical applications, as evidenced by his collaborations on vascular disease treatments currently in advanced stages of preclinical testing.

Lian-Wang Guo, Professor of Biomedical Sciences at the University of Virginia, has earned numerous prestigious awards and honors throughout his distinguished career. In 1996, he received the Award of Excellent Sci/Tech Articles from the Chinese Society of Plant Physiology. He has also been recognized with the University of Wisconsin-Madison Eye Research Institute Rapid Response Initiative Award (2008), the Morgridge Institute for Research Award (2014), and the New Investigator Award from the State of Wisconsin Partnership Program (2014). At The Ohio State University, he earned the Accelerator Award for Translation (2017). His editorial contributions include serving as Lead Guest Editor for Genes and Associate Editor for Frontiers in Cardiovascular Medicine. In 2023, he was elected as a Fellow of the American Heart Association (FAHA), and his outstanding research earned him recognition at the 2023 Research Achievement event at the University of Virginia, marking him as a leading figure in vascular biology and biomedical research.

Dr. Lian-Wang Guo’s extensive research contributions, particularly in vascular biology and epigenetics, position him as a leading scholar in biomedical sciences. His innovative work on chromatin modulators, specifically targeting epigenetic players like BRD4, EZH2, and DOT1L, has brought new insights into the treatment of neointimal-associated vascular diseases. Additionally, his development of nano-based, targeted drug delivery systems has shown promising translational potential, bridging the gap between basic science and clinical applications. With over 20 years of experience, numerous high-impact publications, NIH funding, and significant patents, Dr. Guo’s work is both cutting-edge and impactful. His mentorship of the next generation of scientists, as well as his collaborations with leading clinicians, further enhance his academic profile. While his contributions are already significant, a continued focus on clinical translation could maximize the impact of his research. Overall, Dr. Guo exemplifies the qualities of an outstanding researcher deserving of recognition.

 

Publication top noted
  • Article: Transmembrane protein TMEM97 and epigenetic reader BAHCC1 constitute an axis that supports pro-inflammatory cytokine expression
    Authors: Li, J., Shen, H., Guo, L.-W.
    Year: 2024
    Citations: 0
  • Article: miR579-3p is an inhibitory modulator of neointimal hyperplasia and transcription factors c-MYB and KLF4
    Authors: Xie, X., Shirasu, T., Li, J., Guo, L.-W., Kent, K.C.
    Year: 2023
    Citations: 3
  • Article: Neointima abating and endothelium preserving — An adventitia-localized nanoformulation to inhibit the epigenetic writer DOT1L
    Authors: Shirasu, T., Yodsanit, N., Li, J., Gong, S., Guo, L.-W.
    Year: 2023
    Citations: 1
  • Article: Targeted PERK inhibition with biomimetic nanoclusters confers preventative and interventional benefits to elastase-induced abdominal aortic aneurysms
    Authors: Yodsanit, N., Shirasu, T., Huang, Y., Gong, S., Wang, B.
    Year: 2023
    Citations: 2
  • Article: Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation
    Authors: Zhang, M., Li, J., Wang, Q., Miller, C.L., Guo, L.-W.
    Year: 2023
    Citations: 3
  • Article: Sphingoid Bases Regulate the Sigma-1 Receptor—Sphingosine and N,N’-Dimethylsphingosine Are Endogenous Agonists
    Authors: Li, J., Satyshur, K.A., Guo, L.-W., Ruoho, A.E.
    Year: 2023
    Citations: 3
  • Article: Retinal Photoreceptor Protection in an AMD-Related Mouse Model by Selective Sigma-1 or Sigma-2 Receptor Modulation
    Authors: Mavlyutov, T.A., Li, J., Liu, X., Pattnaik, B., Guo, L.-W.
    Year: 2022
    Citations: 4
  • Erratum: Correction: miR548ai antagonism attenuates exosome-induced endothelial cell dysfunction (Cell Death Discovery, (2021), 7, 1, (318), 10.1038/s41420-021-00720-9)
    Authors: Xie, X., Guo, L.-W., Kent, C.K.
    Year: 2022
    Citations: 0
  • Article: Differential Responses to Sigma-1 or Sigma-2 Receptor Ablation in Adiposity, Fat Oxidation, and Sexual Dimorphism
    Authors: Li, J., Félix-Soriano, E., Wright, K.R., Stanford, K.I., Guo, L.-W.
    Year: 2022
    Citations: 5
  • Article: SREBP1 regulates Lgals3 activation in response to cholesterol loading
    Authors: Li, J., Shen, H., Owens, G.K., Guo, L.-W.
    Year: 2022
    Citations: 9