Dr. Ludivine Delon is an accomplished biomedical researcher with a strong interdisciplinary background in cellular and molecular biology, bioengineering, and microfluidic systems. Her expertise lies in developing advanced organ-on-chip models and gastruloid platforms that simulate human physiological processes for in vitro studies. Throughout her academic and research journey, Dr. Delon has demonstrated an exceptional ability to integrate engineering principles with biomedical applications. Her work has significantly contributed to the fields of nanomedicine, placental biology, and tissue engineering. She has collaborated with prestigious institutions across Australia, Europe, and South America and has been involved in innovative projects that combine organoid culture, microfluidic chip development, and particle transport studies. Dr. Delon’s professional journey is marked by her leadership in designing pioneering microfluidic models and her contributions to the scientific community through peer-reviewed publications, conference presentations, and reviewer roles for renowned journals. In addition to her research activities, she has been actively engaged in mentoring undergraduate and graduate students, highlighting her commitment to academic development. Dr. Delon’s strong publication record, international collaborations, and multidisciplinary approach make her a leading figure in her domain, with her work poised to further influence biomedical research and therapeutic innovations.

Professional Profile

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Education

Dr. Ludivine Delon’s educational journey is distinguished by a consistent pursuit of excellence in the fields of biomaterials engineering, human nutrition, and biomedical sciences. She earned her Ph.D. in Biomaterials Engineering and Nanomedicine from the University of South Australia in 2020, where her doctoral research focused on developing microfluidic intestine-on-a-chip models to study nanoparticle absorption and mucus interaction. Her Ph.D. work was funded by competitive international scholarships and industry-supported grants, showcasing her ability to secure prestigious funding. Prior to this, she obtained an Engineer Diploma in Food Science and a Master of Science in Human Nutrition from Oniris and Université de Nantes, France, where she conducted international research internships in Chile and France. She also completed a Bachelor of Science in Biology, Chemistry, Physics, Mathematics, and Geology at Lycée Henri IV in Paris, France. Additionally, Dr. Delon participated in international exchange programs in Brazil, further enriching her educational experience with a global perspective. Throughout her education, she gained specialized training in organoid culture and microfluidic device fabrication, which laid the foundation for her groundbreaking research in organ-on-a-chip systems. Dr. Delon’s academic path reflects her dedication to combining life sciences with engineering to solve complex biomedical challenges.

Professional Experience

Dr. Ludivine Delon’s professional experience spans across leading research institutions in Norway, Australia, France, and South America, where she has consistently demonstrated expertise in interdisciplinary biomedical research. She currently serves as a Senior Researcher at the University of Oslo’s Institute for Basic Medical Sciences, focusing on human gastruloid development and the design of trophoblast invasion-on-chip models. Prior to this, she worked as a Postdoctoral Research Fellow at the University of Oslo and Oslo University Hospital, where she contributed to groundbreaking projects on human gastruloid vascularisation and placenta-on-chip models. During her doctoral studies at the University of South Australia, she also served as a laboratory demonstrator, where she instructed pharmacy students in dosage form design and pharmaceutical techniques. Additionally, Dr. Delon worked as a teaching assistant in Chile, where she provided guidance in integrated medical case studies. Her professional background also includes valuable industry-related experiences in food science and agricultural product development in France and Ireland. Across all these roles, Dr. Delon has skillfully combined her research capabilities with teaching, laboratory supervision, and international collaboration. Her career reflects her adaptability, leadership in complex scientific projects, and ability to foster innovation across both academic and industrial environments.

Research Interest

Dr. Ludivine Delon’s research interests are centered on the development and application of organ-on-a-chip technologies, microfluidic devices, and human in vitro models to advance biomedical sciences and drug delivery research. Her primary focus lies in studying cellular behavior, tissue differentiation, and nanoparticle transport under physiologically relevant conditions. She is particularly interested in replicating complex human physiological environments, such as intestinal absorption, placental function, and embryonic development, using advanced microfluidic platforms. Dr. Delon is passionate about developing pumpless, recirculating organ-on-a-chip systems that offer more accurate, controllable, and cost-effective models for pharmacological and toxicological studies. Her interest extends to the use of human gastruloids to investigate early developmental processes and the effect of environmental contaminants on cellular interactions. Additionally, she is driven to explore how bioengineering innovations can improve preclinical testing and reduce the need for animal experimentation. Through her interdisciplinary work, Dr. Delon aims to bridge the gap between engineering, biology, and clinical applications by creating reliable models that can revolutionize drug testing, personalized medicine, and developmental biology. Her future research directions include expanding organ-on-chip systems for studying maternal-fetal interfaces and further enhancing the bio-relevance of in vitro platforms for translational research.

Research Skills

Dr. Ludivine Delon possesses a comprehensive and versatile set of research skills that span bioengineering, cellular and molecular biology, and microfluidics. She is highly proficient in microfluidic device fabrication techniques, including photolithography, soft lithography, laser cutting, and hot pressing, as well as in the computational fluid dynamics simulations essential for designing optimized flow conditions. Dr. Delon’s expertise extends to the development of 2D and 3D cellular models, where she is adept at cell culture, immunofluorescence, permeability assays, and complex tissue engineering using a variety of extracellular matrices. She has substantial experience in organoid and gastruloid culture, flow cytometry, lentiviral transfection, and high-resolution microscopy techniques such as confocal imaging and imaging flow cytometry. Additionally, she is skilled in histology, RNA sequencing sample preparation, and permeability studies using transepithelial electrical resistance (TEER) measurements. Dr. Delon’s capabilities also include animal handling for zebrafish and rodent studies, basic bioprinting protocols, and the development of pumpless microfluidic systems with fine fluid control. Her technical competencies are complemented by her strong command of statistical analysis software, image processing tools, and scientific writing platforms. This diverse and advanced skill set enables her to lead complex research projects with high precision and innovation.

Awards and Honors

Dr. Ludivine Delon has received multiple awards and honors that underscore her excellence and impact as a researcher. Her notable accolades include the prestigious International Research Tuition Scholarship awarded by the University of South Australia, which supported her doctoral studies. She also secured competitive travel and conference grants from UniSA, the Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology (CBNS), and Health Development Adelaide, enabling her to present her research at prominent international conferences. Dr. Delon was the People’s Choice winner in the Three-Minute Thesis (3MT) competition, reflecting her strong science communication skills. Her significant contributions to microfluidic device innovation were recognized with a provisional patent on a pumpless microfluidic organ-on-a-chip system, with licensing opportunities to Tekelek Australia. Additionally, she holds a U.S. patent application related to organ-on-chip technology. Dr. Delon’s academic excellence has been consistently acknowledged through scholarships from institutions in France and Brazil, including the Jules Verne and Brafagri exchange program awards. Her awards not only highlight her scientific creativity and technical proficiency but also demonstrate her ability to translate research into impactful applications. These achievements position her as a highly respected and accomplished researcher in her field.

Conclusion

In conclusion, Dr. Ludivine Delon is an outstanding biomedical researcher with a demonstrated record of excellence in organ-on-chip development, biomaterials engineering, and cellular modeling. Her career reflects a rare combination of technical expertise, scientific curiosity, and dedication to advancing preclinical research methods. Dr. Delon’s pioneering contributions to pumpless microfluidic systems, human gastruloid models, and placental studies have positioned her at the forefront of bioengineering innovation. Through her international collaborations, mentorship roles, and consistent publication of high-impact research, she has significantly enriched the scientific community. While her achievements are commendable, expanding her involvement in translational clinical research and leadership in large-scale international projects could further enhance her impact. Dr. Delon’s strong interdisciplinary background, passion for technological advancement, and proven ability to bridge engineering and biology make her an ideal candidate for prestigious research awards. With her forward-thinking approach and commitment to improving in vitro modeling systems, Dr. Delon is well-positioned to continue making transformative contributions to biomedical sciences and global health research in the years to come.

Publications Top Notes

1. A Systematic Investigation of the Effect of the Fluid Shear Stress on Caco-2 Cells Towards the Optimization of Epithelial Organ-on-Chip Models

• Authors: L.C. Delon, Z. Guo, A. Oszmiana, C.C. Chien, R. Gibson, C. Prestidge, et al.

• Journal: Biomaterials 225, 119521

• Year: 2019

• Citations: 156

2. Intestine-on-a-Chip Microfluidic Model for Efficient In Vitro Screening of Oral Chemotherapeutic Uptake

• Authors: K. Pocock, L. Delon, V. Bala, S. Rao, C. Priest, C. Prestidge, B. Thierry

• Journal: ACS Biomaterials Science & Engineering 3 (6), 951-959

• Year: 2017

• Citations: 106

3. Mechanisms of Uptake and Transport of Particulate Formulations in the Small Intestine

• Authors: L. Delon, R.J. Gibson, C.A. Prestidge, B. Thierry

• Journal: Journal of Controlled Release 343, 584-599

• Year: 2022

• Citations: 41

4. Unlocking the Potential of Organ‐on‐Chip Models Through Pumpless and Tubeless Microfluidics

• Authors: L.C. Delon, A. Nilghaz, E. Cheah, C. Prestidge, B. Thierry

• Journal: Advanced Healthcare Materials 9 (11), 1901784

• Year: 2020

• Citations: 38

5. Academic User View: Organ-on-a-Chip Technology

• Authors: M. Busek, A. Aizenshtadt, M. Amirola-Martinez, L. Delon, S. Krauss

• Journal: Biosensors 12 (2), 126

• Year: 2022

• Citations: 30

6. Uptake of Silica Particulate Drug Carriers in an Intestine-on-a-Chip: Towards a Better In Vitro Model of Nanoparticulate Carrier and Mucus Interactions

• Authors: K. Pocock, L.C. Delon, A. Khatri, C. Prestidge, R. Gibson, C. Barbe, B. Thierry

• Journal: Biomaterials Science 7 (6), 2410-2420

• Year: 2019

• Citations: 30

7. Pump-less, Recirculating Organ-on-a-Chip (rOoC) Platform

• Authors: M. Busek, A. Aizenshtadt, T. Koch, A. Frank, L. Delon, M.A. Martinez, et al.

• Journal: Lab on a Chip 23 (4), 591-608

• Year: 2023

• Citations: 26

8. Capturing and Quantifying Particle Transcytosis with Microphysiological Intestine‐on‐Chip Models

• Authors: L.C. Delon, M. Faria, Z. Jia, S. Johnston, R. Gibson, C.A. Prestidge, B. Thierry

• Journal: Small Methods 7 (1), 2200989

• Year: 2023

• Citations: 16

9. Hele Shaw Microfluidic Device: A New Tool for Systematic Investigation into the Effect of the Fluid Shear Stress for Organs-on-Chips

• Authors: L.C. Delon, Z. Guo, M.N. Kashani, C.T. Yang, C. Prestidge, B. Thierry

• Journal: MethodsX 7, 100980

• Year: 2020

• Citations: 16

10. Identifying Human and Murine M Cells In Vitro

• Authors: A. Klisuric, B. Thierry, L. Delon, C.A. Prestidge, R.J. Gibson

• Journal: Experimental Biology and Medicine 244 (7), 554-564

• Year: 2019

• Citations: 13