Matias avila | Medicine and Dentistry | Best Researcher Award
PROFESSOR, SENIOR RESEARCHER, DEPARTMENT CO-DIRECTOR at CIMA. UNIVERSITY OF NAVARRA , Spain.
Matias A. Avila is a distinguished Spanish biochemist and pharmacologist renowned for his groundbreaking research on liver diseases and carcinogenesis. He holds the position of Professor and Department Co-Director at the University of Navarra, where he has made significant contributions to understanding insulin signaling and oncogenic pathways. With an impressive H-index of 63 and over 11,245 citations across 203 publications, his work continues to influence the scientific community. Avila’s leadership extends beyond research, as he actively mentors young scientists and collaborates with industry leaders to translate academic findings into clinical applications. His commitment to scientific excellence is evident through numerous funded research projects and his roles in various scientific committees. Matias Avila’s career reflects a dedication to advancing biomedical research and improving health outcomes, positioning him as a leading figure in his field.
Education📝
Matias A. Avila completed his Pharm. D. degree at Universidad Complutense in Madrid, Spain, in July 1988, specializing in Pharmacological Sciences. He furthered his academic journey by earning a Ph.D. in Biochemistry from the same institution in July 1992. His doctoral research focused on insulin signaling mechanisms and gene regulation, conducted at the Institute for Biomedical Research (IIB) of the National Research Council (CSIC). This foundational education equipped him with a strong understanding of biochemistry and pharmacology, paving the way for his future research endeavors. Avila’s educational background reflects a rigorous academic training that underpins his extensive contributions to liver disease and cancer research. His commitment to education continues through mentoring roles, where he shares his expertise with students and emerging researchers, fostering the next generation of scientists in the field.
Experience👨🏫
Matias A. Avila possesses extensive academic and research experience, primarily at the University of Navarra, where he has served in various capacities since 1998. He started as an Assistant Professor and progressed to Associate Professor and ultimately Full Professor in the Department of Medicine. His leadership roles include Co-Director of the Solid Tumors Program and Director of the Hepatology Program at CIMA-University of Navarra. Avila’s postdoctoral training at Georgetown University enriched his understanding of oncogenic pathways, which he later applied to his research on liver disease. His experience also encompasses collaborations with industry leaders, enhancing translational research efforts. Additionally, his involvement in scientific committees and advisory boards showcases his commitment to advancing research in metabolic and digestive diseases. This rich experience enables him to contribute effectively to academic discussions and shape research initiatives at both national and international levels.
Research Interest🔬
Matias A. Avila’s research interests are centered on liver diseases and cancer, with a particular focus on understanding the mechanisms of insulin signaling and the pathways involved in carcinogenesis. His groundbreaking studies have significantly advanced knowledge in liver regeneration, the role of bile acids in cancer, and epigenetic mechanisms in hepatobiliary tumors. He has been involved in high-impact research projects, including developing peptidomimetics for non-alcoholic steatohepatitis and precision medicine for cholangiocarcinoma. Avila’s work emphasizes translational research, aiming to convert scientific discoveries into practical applications for improving patient outcomes. His collaboration with industry giants like Moderna Therapeutics reflects his commitment to integrating academic research with innovative therapies. By focusing on areas with significant clinical relevance, Avila aims to enhance early diagnostic tools and treatment strategies for hepatobiliary malignancies, thus contributing to better health solutions and improved quality of life for patients.
Awards and Honors🏆
Throughout his career, Matias A. Avila has received numerous accolades recognizing his contributions to biochemistry and pharmacology. Notably, he earned an extraordinary prize for his Ph.D. dissertation, highlighting his early promise in research. His high H-index of 63 and over 11,245 citations reflect his significant impact on the scientific community, with many of his publications recognized in top-tier journals. Avila’s leadership roles, such as Coordinator of the “Metabolic and Digestive Diseases” area and his positions on various scientific committees, further underscore his standing in the field. His involvement in prestigious research projects, funded by notable organizations, showcases the value of his work. These awards and honors not only recognize Avila’s individual achievements but also emphasize his commitment to advancing research in liver diseases and cancer, making him a highly respected figure in the scientific community.
Skills🛠️
Matias A. Avila possesses a diverse skill set that underpins his successful career in biochemistry and pharmacology. His expertise in insulin signaling, gene regulation, and carcinogenesis is complemented by his strong analytical and problem-solving abilities, allowing him to navigate complex scientific challenges effectively. Avila’s proficiency in experimental design and data analysis has led to numerous high-impact publications and successful research projects. His leadership and mentorship skills enable him to guide young scientists and foster collaborative research environments. Additionally, Avila’s experience in industry collaborations enhances his ability to translate academic findings into practical applications, particularly in developing innovative therapies. His strong communication skills facilitate effective engagement with various stakeholders, from students to industry partners and scientific committees. Overall, these skills contribute significantly to his reputation as a leading researcher and mentor in his field.
Conclusion 🔍
In conclusion, Matias A. Avila stands out as an exemplary candidate for the Best Researcher Award due to his extensive academic background, impactful research contributions, and commitment to mentorship. His innovative work in liver disease and cancer has advanced scientific understanding and translated into practical applications, benefiting patients and the broader community. Avila’s leadership roles and collaborations with industry reflect his dedication to fostering a collaborative research environment and bridging the gap between academia and clinical practice. His impressive publication record, high citation metrics, and recognition through various awards underscore his significant influence in the field of biochemistry and pharmacology. As a mentor and leader, Avila continues to inspire and shape the next generation of scientists, solidifying his legacy in the scientific community. His combination of research excellence, leadership, and commitment to mentorship make him a deserving candidate for this prestigious recognition.
Title: Exploring current and emerging therapies for porphyrias
Authors: Jericó, D., Córdoba, K.M., Urigo, F., Ávila, M.A., Fontanellas, A.
Year: 2024
Citation: Liver International, 2024, 44(9), pp. 2174–2190.
Title: Caspases compromise SLU7 and UPF1 stability and NMD activity during hepatocarcinogenesis
Authors: Rojo, C., Gárate-Rascón, M., Recalde, M., Arechederra, M., Berasain, C.
Year: 2024
Citation: JHEP Reports, 2024, 6(8), 101118.
Title: Strategies to enhance the response of liver cancer to pharmacological treatments
Authors: Marin, J.J.G., Macias, R.I.R., Asensio, M., Efferth, T., Briz, O.
Year: 2024
Citation: American Journal of Physiology – Cell Physiology, 2024, 327(1), pp. C11–C33.
Title: Refinement of paramagnetic bead-based digestion protocol for automatic sample preparation using an artificial neural network
Authors: Ciordia, S., Santos, F.M., Dias, J.M.L., Ávila, M.A., Corrales, F.
Year: 2024
Citation: Talanta, 2024, 274, 125988.
Title: Application of Graph Models to the Identification of Transcriptomic Oncometabolic Pathways in Human Hepatocellular Carcinoma
Authors: Barace, S., Santamaría, E., Infante, S., Ávila, M.A., Argemi, J.
Year: 2024
Citation: Biomolecules, 2024, 14(6), 653.
Title: Considering nutritional status to improve outcomes of patients treated by atezolizumab–bevacizumab for advanced hepatocellular carcinoma
Authors: Allaire, M., Ávila, M.A.
Year: 2024
Citation: Liver International, 2024, 44(6), pp. 1276–1277.
Title: New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: A human and experimental study
Authors: Uriarte, I., Santamaria, E., López-Pascual, A., Herrero, I., Ávila, M.A.
Year: 2024
Citation: Biochimica et Biophysica Acta – Molecular Basis of Disease, 2024, 1870(5), 167166.
Title: SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
Authors: Lachiondo-Ortega, S., Rejano-Gordillo, C.M., Simon, J., Rodríguez, M.S., Martínez-Chantar, M.L.
Year: 2024
Citation: Cell Reports, 2024, 43(3), 113924.
Title: Comprehensive in silico CpG methylation analysis in hepatocellular carcinoma identifies tissue- and tumor-type specific marks disconnected from gene expression
Authors: Bilbao, I., Recalde, M., Daian, F., Berasain, C., Arechederra, M.
Year: 2024
Citation: Journal of Physiology and Biochemistry, 2024.
Title: Identification of PRMT5 as a therapeutic target in cholangiocarcinoma
Authors: Elurbide, J., Colyn, L., Latasa, M.U., Fernández-Barrena, M.G., Ávila, M.A.
Year: 2024
Citation: Gut, 2024, gutjnl-2024-332998.