Ms. Mei-Shan Li | Chemistry | Best Researcher Award
Guangxi Normal University | China
Ms. Mei-Shan Li is a dedicated Assistant Researcher at the College of Chemistry and Pharmacy, Guangxi Normal University, China. Her research primarily focuses on organic chemistry, natural product chemistry, and medicinal chemistry, with a particular emphasis on the discovery, structural elucidation, and pharmacological evaluation of bioactive compounds derived from traditional medicinal plants. She has contributed significantly to the exploration of alkaloids, terpenoids, and lignans, elucidating their structural diversity and biological potential in combating cancer, viral infections, and inflammatory diseases. With 18 scientific publications, 121 citations, and an h-index of 7, Ms. Li has established herself as a promising early-career researcher in natural product-based drug discovery. Her works have been published in reputable journals such as Phytomedicine, Fitoterapia, Bioorganic & Medicinal Chemistry, and Chemistry & Biodiversity, where she has often served as a co-first or co-corresponding author, underscoring her leadership and technical expertise. Her studies have provided critical insights into TRPV1 inhibitors, novel anticancer agents, and autophagy-related molecular mechanisms, bridging the gap between traditional herbal medicine and modern pharmacology. Beyond academic publications, Ms. Li has co-invented several national patents in China, covering innovative alkaloid derivatives, sesquiterpenoids, and bioactive extraction methods, which showcase her translational approach from bench research to potential industrial applications. She has participated in multiple National Natural Science Foundation of China (NSFC) and regional research projects, focusing on the pharmacological basis of natural compounds and their therapeutic mechanisms in disease models. Through close collaboration with multidisciplinary teams, Ms. Li’s research contributes to drug discovery, public health improvement, and the scientific validation of traditional Chinese medicines. Her work not only enhances the understanding of medicinal plant chemistry but also promotes the sustainable utilization of natural resources for developing novel therapeutic agents. Ms. Mei-Shan Li continues to advance the frontiers of natural product chemistry with a vision to integrate innovation, sustainability, and societal benefit in her scientific pursuits.
Profile: Scopus
Featured Publications
Fan, C.-W., Tang, J., Jiang, J.-C., Zhou, M.-M., Li, M.-S., & Wang, H.-S. (2022). Pentagalloylglucose suppresses the growth and migration of human nasopharyngeal cancer cells via the GSK3β/β-catenin pathway in vitro and in vivo. Phytomedicine, 102, 154192.
Luo, L., Luo, J.-Z., Fan, C.-W., Song, X.-X., Wang, C.-Y., Tang, D.-M., Sun, W.-T., Fan, C.-W., Li, M.-S., & Wang, H.-S. (2024). Alkaloids from Corydalis saxicola and their antiproliferative activity against cancer cells. Fitoterapia, 173, 105791.
Luo, J.-Z., Li, M.-S., Song, X.-X., Fang, Y.-L., Mo, H.-N., Jiang, J.-C., Zhao, H.-Y., & Wang, H.-S. (2022). New alkaloids and their in vitro antitumor activity of Corydalis balansae. Fitoterapia, 162, 105289.
Qin, F., Li, M.-S., Li, J.-J., Wang, Y., Wang, K., Zhou, J.-Y., Liang, D., & Wang, H.-S. (2022). Four new sesquiterpenoids from Zanthoxylum nitidum. Chemistry & Biodiversity, 19(7), e202200176.
Fan, C.-W., Li, M.-S., Song, X.-X., Luo, L., Jiang, J.-C., Luo, J.-Z., & Wang, H.-S. (2023). Discovery of novel 2-oximino-2-indolylacetamide derivatives as potent anticancer agents capable of inducing cell autophagy and ferroptosis. Bioorganic & Medicinal Chemistry, 80, 117176.