Prof. Itamar Willner | Medicinal Chemistry | Excellence in Research Award
Professor from The Hebrew University of Jerusalem, Israel
Professor Itamar Willner is a distinguished Israeli chemist renowned for his pioneering contributions to supramolecular chemistry, nanotechnology, and nanobiotechnology. Born in January 1947, he has been a faculty member at the Hebrew University of Jerusalem since 1981 and was appointed as a full professor in 1986. His research has significantly advanced the understanding and application of molecular self-assembly, DNA nanotechnology, and bio-hybrid systems. With over 890 scientific publications and more than 100,000 citations, Professor Willner is among the most cited chemists globally, reflecting the profound impact of his work on the scientific community. His innovative approaches have led to the development of DNA-based molecular machines, logic gates, and dynamic networks, bridging the gap between chemistry, biology, and materials science. Throughout his career, he has received numerous prestigious awards, including the Israel Prize in Chemistry, the Rothschild Prize, and the EMET Prize, acknowledging his exceptional contributions to science. Professor Willner’s leadership extends beyond research; he has played pivotal roles in various scientific committees and editorial boards, fostering international collaborations and mentoring the next generation of scientists. His work continues to influence diverse fields, from artificial photosynthesis to smart materials, underscoring his status as a leading figure in contemporary chemistry.
Professional Profile
Education
Professor Willner’s academic journey commenced with a B.Sc. in Chemistry and Physics from the Hebrew University of Jerusalem, completed with distinction. He further pursued an M.Sc. in Chemistry at the same institution, again graduating with distinction. In 1978, he earned his Ph.D. in Physical Organic Chemistry from the Hebrew University, presenting a thesis titled “Novel Series of Polycyclic Aromatic Ions: Aromaticity Structure Relationships,” which was approved summa cum laude. Following his doctoral studies, Professor Willner undertook postdoctoral research at the University of California, Berkeley, from 1978 to 1980, working under the mentorship of Professor Melvin Calvin. This period was instrumental in shaping his future research directions, particularly in the realms of photochemistry and molecular electronics. His comprehensive educational background laid a robust foundation for his subsequent groundbreaking work in chemistry, enabling him to integrate principles from various sub-disciplines and pioneer interdisciplinary research approaches. The rigorous training and diverse academic experiences he acquired during his formative years have been pivotal in his development as a leading scientist in the field.
Professional Experience
Professor Willner’s professional career is marked by a series of esteemed academic and research positions. After completing his postdoctoral fellowship at UC Berkeley, he served as a Staff Scientist and Adjunct Assistant Professor at the same institution from 1980 to 1981. In 1981, he returned to the Hebrew University of Jerusalem as a Senior Lecturer in the Institute of Chemistry. His academic progression continued with his promotion to Associate Professor in 1983 and subsequently to Full Professor in 1986, a position he holds to this day. Beyond his teaching and research responsibilities, Professor Willner has held several significant administrative roles, including Head of the Institute of Chemistry and Chairman of the Natural Sciences Division of the Israel Academy of Sciences and Humanities. He has also been an active member of numerous scientific advisory boards and editorial committees, contributing to the advancement of chemical sciences globally. His professional journey reflects a steadfast commitment to scientific excellence, education, and leadership within the academic community.
Research Interests
Professor Willner’s research interests are deeply rooted in the exploration of supramolecular chemistry, nanotechnology, and biomolecular systems. His work focuses on the design and synthesis of functional nanostructures, particularly those involving DNA nanotechnology, nanoenzymes, and stimuli-responsive materials. He has been instrumental in developing DNA-based molecular machines and logic gates, contributing to the field of molecular computing. His research extends to the construction of bio-nano hybrid systems, integrating biomacromolecules with inorganic nanoparticles to create novel catalytic and sensing platforms. Additionally, Professor Willner has investigated artificial photosynthesis, aiming to mimic natural energy conversion processes for sustainable applications. His interdisciplinary approach combines principles from chemistry, biology, and materials science, leading to innovations in drug delivery systems, biosensors, and smart materials. Through his extensive research, he continues to push the boundaries of molecular design and functional material development.
Research Skills
Professor Willner possesses a diverse set of research skills that have enabled him to make significant contributions to the field of chemistry. His expertise includes the synthesis and characterization of supramolecular assemblies, development of DNA-based nanostructures, and fabrication of bio-nano hybrid systems. He is proficient in employing various spectroscopic and electrochemical techniques to analyze the properties and behaviors of complex molecular systems. His skills extend to the design of molecular machines and logic devices, leveraging the unique properties of nucleic acids and proteins. Furthermore, Professor Willner is adept at integrating biological components with inorganic materials to create functional interfaces for sensing and catalytic applications. His ability to navigate and combine multiple scientific disciplines has been crucial in advancing research in nanobiotechnology and molecular electronics. These competencies have not only facilitated his own research endeavors but have also positioned him as a mentor and leader in the scientific community.
Awards and Honors
Throughout his illustrious career, Professor Willner has received numerous awards and honors recognizing his outstanding contributions to science. Notably, he was awarded the Israel Prize in Chemistry in 2002, one of the country’s highest honors. His accolades also include the Rothschild Prize in Chemistry (2008), the EMET Prize in Chemistry (2008), and the Max Planck Research Award for International Cooperation (1998). He has been elected as a Fellow of the American Association for the Advancement of Science (1996) and the Royal Society of Chemistry (2009). His membership in prestigious academies includes the Israel Academy of Sciences and Humanities (2002), the European Academy of Sciences and Arts (2004), and the German National Academy of Sciences Leopoldina (2009). These honors reflect his significant impact on the scientific community and his role in advancing chemical research on a global scale.
Conclusion
Professor Itamar Willner’s career embodies the pinnacle of scientific achievement and innovation. His extensive research in supramolecular chemistry, nanotechnology, and biomolecular systems has not only expanded the frontiers of chemical science but has also paved the way for practical applications in medicine, energy, and materials science. His interdisciplinary approach and ability to integrate complex systems have resulted in groundbreaking developments, such as DNA-based molecular machines and artificial photosynthetic systems. Beyond his research, Professor Willner’s commitment to education and mentorship has cultivated a new generation of scientists, further amplifying his impact. His numerous awards and memberships in esteemed scientific academies underscore the global recognition of his contributions. As a leading figure in contemporary chemistry, Professor Willner continues to inspire and drive innovation, solidifying his legacy as a pioneer and visionary in the scientific community.
Publications Top Notes
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Title: Integrated nanoparticle–biomolecule hybrid systems: synthesis, properties, and applications
Authors: E. Katz, I. Willner
Journal: Angewandte Chemie International Edition 43(45), 6042–6108
Citations: 3189
Year: 2004 -
Title: Nanoparticle arrays on surfaces for electronic, optical, and sensor applications
Authors: A.N. Shipway, E. Katz, I. Willner
Journal: ChemPhysChem 1(1), 18–52
Citations: 3175
Year: 2000 -
Title: Probing biomolecular interactions at conductive and semiconductive surfaces by impedance spectroscopy: routes to impedimetric immunosensors, DNA‐sensors, and enzyme biosensors
Authors: E. Katz, I. Willner
Journal: Electroanalysis
Citations: 1648
Year: 2003 -
Title: “Plugging into enzymes”: Nanowiring of redox enzymes by a gold nanoparticle
Authors: Y. Xiao, F. Patolsky, E. Katz, J.F. Hainfeld, I. Willner
Journal: Science 299(5614), 1877–1881
Citations: 1520
Year: 2003 -
Title: Diverse applications of nanomedicine
Authors: B. Pelaz, C. Alexiou, R.A. Alvarez-Puebla, F. Alves, A.M. Andrews, S. Ashraf, …
Journal: ACS Nano 11(3), 2313–2381
Citations: 1381
Year: 2017 -
Title: Integration of layered redox proteins and conductive supports for bioelectronic applications
Authors: I. Willner, E. Katz
Journal: Angewandte Chemie International Edition 39(7), 1180–1218
Citations: 1309
Year: 2000 -
Title: Biomolecule‐functionalized carbon nanotubes: applications in nanobioelectronics
Authors: E. Katz, I. Willner
Journal: ChemPhysChem 5(8), 1084–1104
Citations: 1089
Year: 2004 -
Title: Semiconductor quantum dots for bioanalysis
Authors: R. Gill, M. Zayats, I. Willner
Journal: Angewandte Chemie International Edition 47(40), 7602–7625
Citations: 1026
Year: 2008 -
Title: Electronic aptamer‐based sensors
Authors: I. Willner, M. Zayats
Journal: Angewandte Chemie International Edition 46(34), 6408–6418
Citations: 912
Year: 2007 -
Title: Electroanalytical and bioelectroanalytical systems based on metal and semiconductor nanoparticles
Authors: E. Katz, I. Willner, J. Wang
Journal: Electroanalysis
Citations: 912
Year: 2004