Lan Hong | Biochemistry | Best Researcher Award

Prof. Lan Hong | Biochemistry | Best Researcher Award

Professor at Yanbian University, China

Dr. Lan Hong, a Professor in the Department of Physiology and Pathophysiology at Yanbian University’s College of Medicine, has dedicated her career to advancing knowledge in cardiovascular physiology, with a specialized focus on cardiac protection mechanisms and stem cell therapy. With over 18 years of experience, Dr. Hong’s research addresses critical challenges in cardiovascular health, particularly in understanding and treating ischemia-reperfusion injuries and myocardial infarction. She has made substantial contributions to the field through high-impact publications, collaborative research initiatives, and conference presentations. As a recognized figure in her field, she has also served as a visiting scholar at Texas A&M University-Commerce, where she expanded her work on regenerative medicine, specifically focusing on cardiac-induced RNA and pluripotent stem cells. Dr. Hong’s research is well-cited, with an H-index of 10 and a citation count of over 300, reflecting her influence in cardiac physiology research. Her extensive involvement in academic conferences, journal reviews, and mentoring has bolstered her reputation as a leader in cardiovascular research. She is also recognized through multiple awards and invitations to present her research, which underscores her commitment to advancing the understanding and treatment of cardiovascular diseases.

Professional Profile

Education

Dr. Lan Hong’s educational journey is anchored in her commitment to understanding the intricacies of cardiovascular physiology. She earned her PhD in Physiology from Yanbian University in 2012, where she also completed her MSc in the same field in 2009. Prior to her postgraduate studies, she graduated with a degree in Clinical Medicine from Yanbian University in 2006, which laid the foundation for her subsequent research in cardiac health. Her academic path reflects a deep specialization in cardiac physiology, particularly in exploring protective mechanisms for the heart and developing innovative treatments for cardiovascular diseases. Throughout her education, Dr. Hong cultivated a robust theoretical and practical understanding of physiology, providing a strong foundation for her later research on myocardial infarction and stem cell therapy. Her scholarly background, coupled with hands-on experience in clinical medicine, has greatly enriched her approach to research, enabling her to bridge the gap between theoretical knowledge and clinical application in her ongoing studies.

Professional Experience

Dr. Lan Hong has built a distinguished career as a cardiovascular researcher, currently serving as a Professor at the College of Medicine at Yanbian University, where she has worked since 2013. She initially joined the university’s Department of Physiology and Pathophysiology as an Assistant Professor, where her research began to focus on ischemia-reperfusion injury and cardiac fibrosis mechanisms. Her career includes international experience as a visiting scholar and postdoctoral researcher at Texas A&M University-Commerce from 2017 to 2018. During her tenure there, she collaborated on groundbreaking work using cardiac-inducing RNA and stem cell technology for post-infarction heart repair. Dr. Hong’s role as an educator and mentor is integral to her professional experience, as she has supervised graduate students, organized research conferences, and contributed as a reviewer for respected journals. Her professional trajectory reflects a consistent dedication to advancing cardiovascular health and supporting academic development in her field, cementing her reputation as a respected academic and researcher in cardiovascular physiology.

Research Interests

Dr. Lan Hong’s research interests center on cardiovascular physiology, with a particular emphasis on mechanisms of cardiac protection and regeneration. Her work seeks to address key challenges in treating myocardial infarction and mitigating ischemia-reperfusion injury. One of her primary research interests is exploring molecular pathways such as the Sirt1/Nrf2/ATF3/4 axis and the role of ferroptosis in cardiac injury. Additionally, Dr. Hong is committed to advancing stem cell therapy, specifically investigating the regenerative potential of induced pluripotent stem cells in cardiac repair. Her studies also delve into the role of long non-coding RNAs (lncRNAs) in modulating cellular responses to injury and in promoting cardiomyocyte regeneration. By targeting these cellular pathways, Dr. Hong aims to develop novel therapeutic approaches that offer improved outcomes for patients with cardiovascular conditions. Her research interests reflect a balanced approach that combines molecular biology, regenerative medicine, and clinical application, making significant strides in cardiovascular health advancements.

Research Skills

Dr. Lan Hong’s research skills are rooted in a robust knowledge of cardiovascular physiology, paired with technical expertise in cellular and molecular biology techniques. She is proficient in various lab methodologies essential to cardiac physiology research, including in vitro and in vivo models for studying ischemia-reperfusion injury and myocardial infarction. Dr. Hong’s work with stem cells, particularly induced pluripotent stem cells, requires advanced skills in cellular reprogramming and RNA-mediated gene expression techniques. Her proficiency extends to molecular techniques such as Western blotting, immunohistochemistry, and real-time PCR, which she utilizes to investigate gene expression patterns and protein signaling in cardiac tissues. Her ability to perform complex experimental procedures, analyze data critically, and interpret results within the context of cardiovascular health has made her research impactful and well-regarded. Dr. Hong’s research skills are complemented by her collaborative approach, which has facilitated cross-disciplinary studies and allowed her to mentor students effectively, contributing to the next generation of cardiovascular researchers.

Awards and Honors

Throughout her career, Dr. Lan Hong has received recognition for her contributions to cardiovascular research. Her work has earned her multiple awards, reflecting her expertise and influence in cardiac physiology. She has been invited to present her findings at national and international conferences, showcasing her research on ischemia-reperfusion injury and stem cell therapy. Her role as an invited speaker demonstrates the high regard in which her peers hold her work and highlights her contributions to advancing cardiovascular health. Additionally, Dr. Hong’s editorial and peer-review roles for respected journals underscore her commitment to maintaining rigorous standards in scientific research and her influence in the academic community. Her research achievements, high-impact publications, and the positive impact of her mentorship have solidified her standing as a leader in cardiovascular physiology. Her recognition through these awards and honors underscores her dedication to her field and highlights her impact on the scientific understanding of cardiac health and disease.

Conclusion

Lan Hong’s extensive research and contributions in cardiovascular physiology, along with her impactful publications, make her a strong candidate for the Best Researcher Award. Her international experience, academic achievements, and innovative work in cardiac protection mechanisms are commendable. Addressing minor gaps in industry collaboration and expanding her professional presence may further strengthen her profile for future recognitions. Overall, her dedication to advancing cardiovascular health and her achievements make her highly deserving of the award.

Publications Top Notes

  1. Synthesis and antibacterial evaluation of rhodanine-based 5-aryloxy pyrazoles against selected methicillin-resistant and quinolone-resistant Staphylococcus aureus (MRSA and QRSA)”
    Authors: MX Song, CJ Zheng, XQ Deng, LP Sun, Y Wu, L Hong, YJ Li, Y Liu, …
    Journal: European Journal of Medicinal Chemistry, 60, 376-385
    Year: 2013
    Citations: 57
  2. “MAPK and PI3K pathways regulate hypoxia-induced atrial natriuretic peptide secretion by controlling HIF-1 alpha expression in beating rabbit atria”
    Authors: Q Zhang, B Cui, H Li, P Li, L Hong, L Liu, D Ding, X Cui
    Journal: Biochemical and Biophysical Research Communications, 438 (3), 507-512
    Year: 2013
    Citations: 38
  3. “Atrial natriuretic peptide prevents the mitochondrial permeability transition pore opening by inactivating glycogen synthase kinase 3β via PKG and PI3K in cardiac H9c2 cells”
    Authors: L Hong, J Xi, Y Zhang, W Tian, J Xu, X Cui, Z Xu
    Journal: European Journal of Pharmacology, 695 (1-3), 13-19
    Year: 2012
    Citations: 37
  4. “Synthesis and biological evaluation of 5-aryloxypyrazole derivatives bearing a rhodanine-3-aromatic acid as potential antimicrobial agents”
    Authors: CJ Zheng, MX Song, LP Sun, Y Wu, L Hong, HR Piao
    Journal: Bioorganic & Medicinal Chemistry Letters, 22 (23), 7024-7028
    Year: 2012
    Citations: 35
  5. “Synthesis and positive inotropic activity of N-(4, 5-dihydro-[1, 2, 4] triazolo [4, 3-a] quinolin-7-yl)-2-(piperazin-1-yl) acetamide derivatives”
    Authors: CB Zhang, X Cui, L Hong, ZS Quan, HR Piao
    Journal: Bioorganic & Medicinal Chemistry Letters, 18 (16), 4606-4609
    Year: 2008
    Citations: 26
  6. “Adenosine A2 receptor activation ameliorates mitochondrial oxidative stress upon reperfusion through the posttranslational modification of NDUFV2 subunit of complex I in the heart”
    Authors: J Xu, X Bian, Y Liu, L Hong, T Teng, Y Sun, Z Xu
    Journal: Free Radical Biology and Medicine, 106, 208-218
    Year: 2017
    Citations: 22
  7. “Ethanol attenuates sensory stimulus-evoked responses in cerebellar granule cells via activation of GABAA receptors in vivo in mice”
    Authors: G Wu, H Liu, J Jin, L Hong, Y Lan, CP Chu, DL Qiu
    Journal: Neuroscience Letters, 561, 107-111
    Year: 2014
    Citations: 19
  8. “Ouabain stimulates atrial natriuretic peptide secretion via the endothelin-1/ETB receptor-mediated pathway in beating rabbit atria”
    Authors: L Liu, L Hong, L Yu, H Li, D Ding, S Jin, X Cui
    Journal: Life Sciences, 90 (19-20), 793-798
    Year: 2012
    Citations: 16
  9. “Cathepsins in the extracellular space: Focusing on non-lysosomal proteolytic functions with clinical implications”
    Authors: H Wang, A Inoue, Y Lei, H Wu, L Hong, XW Cheng
    Journal: Cellular Signalling, 103, 110531
    Year: 2023
    Citations: 13

 

Dr. Florence Back | Biochemistry | Best Researcher Award

Dr. Florence Back | Biochemistry | Best Researcher Award

Doctorate at University of Lille, France

Florence Back is a distinguished biomaterials scientist and researcher specializing in bioadhesive and smart wound-healing technologies. Based in Strasbourg, France, she has made significant strides in developing innovative materials for medical applications, including hydrogels and electronic patches for therapeutic uses. Florence’s work is underpinned by advanced training in in vivo procedures and applied chemistry, making her well-versed in both the laboratory synthesis of biomaterials and preclinical surgical applications. Her research has been published in reputable journals, highlighting her commitment to advancing the fields of bioengineering and regenerative medicine. Florence’s research integrates expertise across biology, chemistry, and physics, emphasizing both material functionality and patient-centered applications. She has been involved in collaborative research at prestigious institutions, including CNRS Lille and UC Louvain, and is actively expanding her interdisciplinary contributions to wound care, tissue repair, and bioengineering.

Professional Profile

Education

Florence holds a Ph.D. in Biomaterials from UNISTRA Strasbourg, completed in 2022, where she focused on the synthesis and development of bioadhesives based on gelatin and catechol. This work involved extensive research into the formulation, spectroscopic characterization, and rheological analysis of these bioadhesives. Her doctoral studies were preceded by two specialized master’s degrees, both from UNISTRA Strasbourg, in supramolecular and macromolecular chemistry, completed in 2020 and 2019, respectively. Florence’s master’s education covered advanced techniques in organic and polymer synthesis, including the creation of fluorescent molecules and polymers with unique biochemical properties. Her academic journey includes a series of certifications in in vivo procedures from CNRS Lille, where she developed critical surgical skills required for research involving animal models. Florence’s education has been integral in building her comprehensive understanding of biomaterials and in vivo applications, positioning her as a skilled researcher in medical and chemical sciences.

Professional Experience

Florence’s professional experience includes postdoctoral research and engineering roles focused on advancing biomaterial applications in medicine. Currently, she is a postdoctoral researcher at UC Louvain in Belgium, working on the AI-SWEEP-2 project, which involves the synthesis of electronic patches for smart bandages intended for human use. Prior to this, she served as a biomaterials engineer at CNRS Lille, where she contributed to the ANR Gskin project, focusing on synthesizing and characterizing hydrogels doped with extracellular vesicles for diabetic wound healing. From 2020 to 2022, during her Ph.D. at the Dental Faculty of Strasbourg, Florence specialized in the synthesis of bioadhesives based on gelatin and catechol, marking the beginning of her notable contributions to biomaterials science. These roles have allowed her to develop an integrated approach to material synthesis, characterization, and biological application, emphasizing her commitment to innovation in therapeutic and regenerative materials.

Research Interests

Florence’s research interests center on biomaterials, bioadhesives, and smart wound-healing technologies. Her primary focus is the development and synthesis of bioadhesive hydrogels, which hold promise in tissue repair and regenerative medicine. Additionally, her work extends to smart bandages, integrating electronic patches for wound monitoring and therapeutic delivery, aimed at improving patient outcomes in wound care. She is also interested in the extraction and application of extracellular vesicles in biomaterials, with specific attention to their role in promoting cellular viability and tissue regeneration. Florence’s research leverages a multidisciplinary approach, combining chemistry, biology, and materials science to create innovative solutions that bridge the gap between synthetic materials and biological functions. Her commitment to research that addresses clinical challenges underscores her dedication to advancing biomaterials for direct medical applications.

Research Skills

Florence’s research skills encompass a wide range of laboratory and analytical techniques, particularly in chemistry, biology, and materials science. She is proficient in organic and polymer synthesis, including gel formulation and the development of bioadhesive materials from gelatin, chitosan, and silk hydrogels. Her technical skills include chromatography, spectroscopy (NMR, IR, UV-Vis), and nanoparticle tracking analysis, which she applies in the characterization of synthesized materials. Florence is also skilled in in vivo procedures, certified for surgeries and techniques on various animal models, such as vascular catheterization, cerebral ischemia, and renal grafting. Additionally, her experience extends to cell culture, viability testing, and supervising research protocols. Florence’s ability to conduct comprehensive material characterization combined with her surgical training in vivo highlights her versatility and readiness to bridge laboratory research with applied medical sciences.

Awards and Honors

Florence has achieved various recognitions that reflect her dedication to research excellence in biomaterials. Her doctoral research at UNISTRA Strasbourg earned her acclaim for creating bioadhesive formulations with potential applications in tissue engineering and wound care. Her work has been published in notable journals, including Frontiers in Materials and Gels, indicating her research’s value to the academic and clinical communities. Florence’s role in collaborative projects, such as the ANR Gskin and AI-SWEEP-2, highlights her contributions to interdisciplinary research initiatives aimed at developing innovative therapeutic technologies. Additionally, her certifications in in vivo procedures from CNRS Lille are a testament to her commitment to ethical and skillful research practices. Florence’s career trajectory, marked by research achievements and collaborative contributions, positions her as a promising candidate for awards in scientific innovation and applied biomaterials.

Conclusion

Florence Back demonstrates strong candidacy for a “Best Researcher Award” due to her advanced technical skills in biomaterials, substantial in vivo training, and impactful research in bioadhesives and smart bandage technologies. By addressing minor language skills and pursuing independent research initiatives, she could amplify her contributions and influence in the field.

Publication Top Notes

  1. Optimization of the Elasticity and Adhesion of Catechol- or Dopamine-Loaded Gelatin Gels under Oxidative Conditions
    • Authors: F. Back, E. Mathieu, C. Betscha, Y. Arntz, V. Ball
    • Journal: Gels
    • Year: 2022
    • Volume & Issue: 8(4), Article 210
    • Citations: 7
    • Open Access: Yes
  2. Influence of the NaIO₄ Concentration on the Gelation and the Adhesive Strength of Pyrocatechol/Pyrogallol Containing Gelatin Hydrogels
    • Authors: F. Back, V. Ball, Y. Arntz
    • Journal: Frontiers in Materials
    • Year: 2021
    • Volume & Article: 8, Article 671451
    • Citations: 4
    • Open Access: Yes