Xue-Qiang Wang | Chemistry | Best Researcher Award

Prof. Dr. Xue-Qiang Wang | Chemistry | Best Researcher Award

Associate Director at Hangzhou Insitutte of Medicine, CAS, China

Prof. Dr. Xue-Qiang Wang is a distinguished researcher and group leader at the Hangzhou Institute of Medical Sciences, Chinese Academy of Sciences (CAS). His expertise lies in developing innovative molecular tools and therapies for precision medicine, particularly in cancer treatment and bioimaging. With a strong academic foundation from leading institutions in China, Spain, and the United States, he has established himself as a leader in chemical and biomedical research. His work focuses on multi-specific aptamer construction, targeted radionuclide drugs, and chemiluminescence probe design. Over the years, he has authored more than 30 high-impact journal publications and received numerous prestigious awards, highlighting his contributions to science and technology. His research has significant implications for precision medicine, offering novel solutions for disease detection and treatment.

Professional Profile

Education

Prof. Dr. Xue-Qiang Wang earned his master’s degree from the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, in 2012. He then pursued his Ph.D. at the Institute of Chemical Research of Catalonia, Spain, completing it in 2015. Following his doctoral studies, he engaged in postdoctoral research at the Massachusetts Institute of Technology (MIT) in the United States from 2016 to 2017. His educational background reflects extensive interdisciplinary training, combining organic chemistry, biomedical sciences, and advanced analytical techniques. This diverse academic experience has enabled him to contribute to cutting-edge research in chemical biology and medical science.

Professional Experience

Dr. Wang’s professional journey began with his postdoctoral research at MIT, where he worked on advanced molecular technologies. In 2017, he joined the College of Chemistry and Chemical Engineering at Hunan University, where he contributed significantly to the Laboratory of Molecular Science and Biomedicine. His tenure at Hunan University allowed him to develop key research projects and mentor young scholars. In 2023, he transitioned to the Hangzhou Institute of Medical Sciences, CAS, where he currently leads a research group dedicated to developing novel biomedical applications. His leadership in this field has positioned him as an influential scientist, driving innovation in targeted therapies and diagnostic tools.

Research Interests

Dr. Wang’s research interests focus on the intersection of chemistry, molecular biology, and medicine. His work primarily revolves around multi-specific aptamer construction for precision cancer therapy, which involves designing nucleic acid-based molecules for targeted drug delivery. Another key area of his research is the development of targeted radionuclide drugs, which use radioactive compounds for cancer treatment. Additionally, he specializes in chemiluminescence probe design, enabling precise bioimaging techniques for disease detection and monitoring. These research interests contribute to advancing molecular medicine, providing new therapeutic and diagnostic solutions.

Research Skills

Dr. Wang possesses extensive expertise in molecular design, synthetic chemistry, and biomedical applications. His skills include nucleic acid aptamer development, radiopharmaceutical synthesis, and chemiluminescence probe engineering. He is proficient in advanced analytical techniques such as high-performance liquid chromatography (HPLC), mass spectrometry, and fluorescence imaging. His experience in interdisciplinary collaboration allows him to integrate chemistry, biology, and medical sciences to develop innovative solutions. He also has strong leadership and mentorship skills, guiding research teams and fostering academic excellence. His ability to translate laboratory findings into practical applications makes him a key figure in precision medicine research.

Awards and Honors

Dr. Wang’s contributions to science have earned him several prestigious awards and recognitions. In 2019, he was selected for the Huxiang Young Talents Program, which acknowledges promising researchers. In 2021, he was honored with the Hunan Province Furong Scholars Award Program – Distinguished Professor, recognizing his academic excellence. He received the 2022 Hunan Province Outstanding Youth Project grant, supporting his innovative research. Additionally, he was awarded the 2022 Thieme Chemistry Journals Award for his significant contributions to chemistry. In 2023, he was recognized as a Ministry of Education Young Yangtze Scholar, further solidifying his status as a leading researcher in China.

Conclusion

Prof. Dr. Xue-Qiang Wang is an accomplished scholar with a remarkable academic and professional trajectory. His contributions to molecular science and biomedical research have led to significant advancements in targeted cancer therapy and bioimaging. Through his leadership roles, impactful research publications, and numerous accolades, he has demonstrated excellence in his field. His interdisciplinary expertise in chemistry and medical sciences positions him as a key innovator, driving progress in precision medicine. As he continues to expand his research and collaborations, his work is set to have a lasting impact on healthcare and molecular diagnostics.

Publication Top Notes

  1. Title: “Development of Polymeric Aptamer Probes for In Vivo Continuous Precision Cancer Targeting”

    • Authors: Silin Huang, Yu-Ting He, Xiao-Jing Zhang, Xue-Qiang Wang, Qiang Guo
    • Year: 2025
    • Source: Materials Chemistry Frontiers
    • DOI: 10.1039/D4QM00731J
  2. Title: “Bisboronic Ester-Enabled Redox-Targeted Cancer Therapy: A Cascade ROS Consumption Approach for Efficient Elimination of Cancer Cells”

    • Authors: Silin Huang, Yue Cui, Boqiang Wang, Fang-Jie Liu, Jia-Yi Liu, Wen Shao, Xue-Qiang Wang, Qiang Guo
    • Year: 2025
    • Source: Journal of Medicinal Chemistry
    • DOI: 10.1021/acs.jmedchem.5c00038
  3. Title: “A Bicyclic Dioxetane Chemiluminescence Nanoprobe for Peroxynitrite Imaging In Vivo”

    • Authors: Min Shi, Yun Zhang, Jia-Xing Chen, Yanyuan Wu, Zongping Wang, Peng-Fei Shi, Xudong Jin, Xue-Qiang Wang
    • Year: 2024
    • Source: Analytical Chemistry
    • DOI: 10.1021/acs.analchem.4c04510
  4. Title: “An Aptamer Glue Enables Hyperefficient Targeted Membrane Protein Degradation”

    • Authors: Guo-Rong Zhang, Chi Zhang, Ting Fu, Weihong Tan, Xue-Qiang Wang
    • Year: 2024
    • Source: JACS Au
    • DOI: 10.1021/jacsau.4c00260
  5. Title: “Polyfluoroalkyl Tag Decoration Enables Significantly Enhanced Tumor Penetration Ability of a PTK7 Targeting Aptamer”

    • Authors: Yingying Li, Chi Zhang, Ting Fu, Xue-Qiang Wang, Weihong Tan
    • Year: 2024
    • Source: Bioconjugate Chemistry
    • DOI: 10.1021/acs.bioconjchem.4c00131
  6. Title: “Ni-Catalyzed Csp2 and Csp3 Coupling for Divergent Bisboronic Ester Synthesis”

    • Authors: Yue Cui, Shi-Tang Xu, Cheng-Yu Long, Shen-Huan Li, Jie Shen, Ting Fu, Xin-Hua Xu, Xue-Qiang Wang
    • Year: 2024
    • Source: Organic Letters
    • DOI: 10.1021/acs.orglett.4c00904
  7. Title: “Cobalt-Catalyzed Selective Hydroboration of 1,3-Enynes with HBpin toward 1,3-Dienylboronate Esters”

    • Authors: Yining Jia, Liu Yang, Xueqiang Wang, Wen Yang, Wanxiang Zhao
    • Year: 2024
    • Source: Organic Letters
    • DOI: 10.1021/acs.orglett.4c00899
  8. Title: “High Contrast Bioimaging of Tumor and Inflammation with a Bicyclic Dioxetane Chemiluminescent Probe”

    • Authors: Qian Shang, Shen-Huan Li, Yu-Ting He, Yun Zhang, Ting Fu, Shi-Song Han, Wenshan Huang, Xue-Qiang Wang, Jie-Hua Xu
    • Year: 2024
    • Source: Analytical Chemistry
    • DOI: 10.1021/acs.analchem.3c05062
  9. Title: “Correction to ‘Ni-Catalyzed Protecting Group Free Diphenic Acid Analog Synthesis'”

    • Authors: Bo-Wei Zhao, Liu Yang, Cheng-Yu Long, Han-Lu Li, Yu-Ting He, Xue-Qiang Wang
    • Year: 2023
    • Source: Organic Letters
    • DOI: 10.1021/acs.orglett.3c02514
  10. Title: “Emission Wavelength-Tunable Bicyclic Dioxetane Chemiluminescent Probes for Precise In Vitro and In Vivo Imaging”

    • Authors: Shen-Huan Li, Guo-Rong Zhang, Yu-Ting He, Liu Yang, Han-Lu Li, Cheng-Yu Long, Yue Cui, Xue-Qiang Wang
    • Year: 2023
    • Source: Analytical Chemistry
    • DOI: 10.1021/acs.analchem.3c02126

 

Shishu Yang | Chemistry | Best Researcher Award

Dr. Shishu Yang | Chemistry | Best Researcher Award

Secretary at Henan Normal University, China

Shishu Yang is a dedicated researcher in the field of nanomaterials, with a particular focus on nanoscale metal-organic frameworks (MOFs) and covalent organic frameworks (COFs). He obtained his Ph.D. from Nanjing Normal University in 2021 under the supervision of Prof. Zhi-Yuan Gu. Since then, he has been serving as a lecturer at Henan Normal University in the School of Chemistry and Chemical Engineering. His research primarily revolves around pore engineering in nanoscale materials and their applications in sample preparation, particularly in biomolecular enrichment and analysis. With several high-impact journal publications, his work contributes significantly to advancements in analytical chemistry and nanotechnology. His research findings offer promising applications in proteomics, diagnostics, and chemical sensing. He has also contributed to peer review activities for international journals, reflecting his engagement with the scientific community. Despite being an early-career researcher, his contributions to the field are noteworthy. His work has the potential to bridge fundamental materials science with real-world biomedical applications, making him a strong candidate for recognition in the scientific community. Expanding his research through collaborations, leadership roles, and funding acquisition could further enhance his academic and professional standing.

Professional Profile

Education

Shishu Yang completed his Ph.D. in Chemistry at Nanjing Normal University in 2021 under the guidance of Prof. Zhi-Yuan Gu. His doctoral research was centered on the development of nanoscale metal-organic frameworks (MOFs) with tailored pore structures for applications in sample preparation. His studies involved advanced material synthesis, characterization, and application of porous materials in biomolecular analysis. During his doctoral program, he gained expertise in designing highly selective materials for peptide and glycopeptide enrichment, an essential aspect of proteomics research. His academic training provided him with a strong foundation in nanomaterials, surface chemistry, and analytical techniques. His research work was published in reputed journals, showcasing his ability to conduct independent and high-quality research. Prior to his Ph.D., he likely completed his undergraduate and master’s education in chemistry or a related discipline, though specific details are not provided. His academic background has enabled him to develop strong problem-solving skills and an innovative approach to scientific research. His training at Nanjing Normal University, a well-regarded institution, has prepared him for a career in academia and research, focusing on the development of functional materials for chemical and biomedical applications.

Professional Experience

Since July 2021, Shishu Yang has been serving as a lecturer at Henan Normal University in the School of Chemistry and Chemical Engineering. In this role, he is involved in teaching, research, and mentoring students. His work primarily revolves around material synthesis, with a focus on nanoscale metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) for applications in analytical chemistry. His experience includes conducting independent research, publishing in high-impact journals, and collaborating with peers in the field. In addition to his teaching and research responsibilities, he has contributed to the scientific community as a peer reviewer for journals such as International Journal of Biological Macromolecules and Small Methods. His expertise in nanomaterials and biomolecular enrichment techniques positions him as a valuable member of the academic community. Although still in the early stages of his career, he has demonstrated significant research potential. To further establish himself as a leading researcher, expanding his professional experience through collaborative projects, securing research funding, and participating in international conferences would be beneficial. His role at Henan Normal University provides a strong platform for his academic and research pursuits.

Research Interest

Shishu Yang’s research interests lie in the development and application of nanoscale porous materials, particularly metal-organic frameworks (MOFs) and covalent organic frameworks (COFs). His primary focus is on pore engineering to enhance the efficiency of these materials in sample preparation, including the selective enrichment of biomolecules such as peptides and glycopeptides. His work is highly relevant to analytical chemistry, proteomics, and biomedical diagnostics. He is also interested in the use of two-dimensional nanomaterials for chemical sensing, exploring their potential for applications in molecular recognition and disease biomarker detection. His studies aim to design highly efficient materials with tailored functionalities for real-world applications in biochemical analysis. The development of novel materials with high specificity and selectivity in molecular recognition is a key aspect of his research. His work bridges fundamental material science with applied chemistry, offering solutions for high-precision biomolecular analysis. Future research directions could involve expanding his expertise into hybrid nanomaterials, integrating MOFs and COFs with other functional materials for enhanced analytical performance. His research has the potential to impact various fields, including pharmaceuticals, environmental monitoring, and biomedical diagnostics.

Research Skills

Shishu Yang possesses a diverse set of research skills that align with his expertise in nanomaterials and analytical chemistry. He has extensive experience in the synthesis and characterization of metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), particularly in optimizing their pore structures for targeted applications. His analytical skills include proficiency in chromatography, mass spectrometry, and spectroscopy techniques, which are essential for studying biomolecular interactions. He is skilled in developing novel materials for selective peptide and glycopeptide enrichment, an area crucial for proteomics and disease biomarker discovery. His ability to design and evaluate functional nanomaterials demonstrates his strong problem-solving skills and innovative thinking. Additionally, he has experience in data analysis, scientific writing, and peer review, contributing to his ability to publish in high-impact journals. His research expertise extends to two-dimensional nanomaterials for chemical sensing, showcasing his interdisciplinary approach. Moving forward, gaining hands-on experience in computational modeling and machine learning applications in material design could enhance his research capabilities. His technical proficiency, combined with his analytical and experimental skills, makes him a valuable researcher in the field of nanomaterials and analytical chemistry.

Awards and Honors

There is no specific mention of awards and honors in the available information on Shishu Yang. However, his publication record in high-impact journals suggests recognition within the academic and research community. His contributions to analytical chemistry and nanomaterials research indicate a strong potential for future accolades. As an early-career researcher, he may have received internal university grants, research fellowships, or conference presentation awards, though such details are not specified. To further establish his academic standing, applying for research grants, young investigator awards, and international fellowships would be beneficial. Additionally, securing patents or technology transfer initiatives could enhance his recognition in applied research. Being actively involved in scientific societies and conference organizations could also lead to awards for research excellence. While he may not have received formal awards yet, his research achievements indicate a promising career trajectory that could lead to future honors.

Conclusion

Shishu Yang is an emerging researcher with strong expertise in nanomaterials, particularly metal-organic frameworks (MOFs) and covalent organic frameworks (COFs). His work in biomolecular enrichment and chemical sensing contributes significantly to analytical chemistry and biomedical applications. His academic and research journey from Nanjing Normal University to Henan Normal University reflects his dedication to scientific progress. With multiple high-impact publications, he has demonstrated the ability to conduct innovative research. While he has a solid foundation, expanding his research impact through collaborations, funding acquisition, and leadership roles would strengthen his profile. His engagement in peer review activities highlights his commitment to the scientific community. Though specific awards and honors are not mentioned, his research excellence positions him as a strong candidate for future recognition. Moving forward, increasing his international collaborations and applying for prestigious research awards could further enhance his career. Overall, his contributions to the field make him a valuable researcher with significant potential for academic and professional growth.

Publication Top Notes

  1. Hydrophilic Sulfonate Covalent Organic Frameworks for Serum Glycopeptide Profiling

    • Authors: Shishu Yang, Yuheng Jiang, Shijie Jiang, Lihong Liu, Si Liu, Hua Zhang, Zhiyuan Gu
    • Year: 2025
  2. Triazine-structured covalent organic framework nanosheets with inherent hydrophilicity for the highly efficient and selective enrichment of glycosylated peptides

    • Authors: Shi-Shu Yang, Yu-Heng Jiang, Xuan Zhang, Li-Hong Liu, Si Liu, Hua Zhang
    • Year: 2024
  3. Three-Dimensional MAX-Ti3AlC2 Nanomaterials for Dual-Selective and Highly Efficient Enrichment of Phosphorylated and Glycosylated Peptides

    • Authors: Shi-Shu Yang, Chen Wang, Yu-Fei Jiang, Hua Zhang
    • Year: 2023
  4. Two-dimensional materials as solid-state nanopores for chemical sensing

    • Authors: Zhan Wang, Tian-Yi Lv, Zi-Bo Shi, Shi-Shu Yang, Zhi-Yuan Gu
    • Year: 2021
  5. Highly efficient enrichment of N-glycopeptides by two-dimensional Hf-based metal–organic framework nanosheets

    • Authors: Shi-Shu Yang, Chen Wang, Jing Xiao, Xizhong Yu, Wenbin Shang, David Da Yong Chen, Zhi-Yuan Gu
    • Year: 2020
  6. Enrichment of Phosphorylated Peptides with Metal–Organic Framework Nanosheets for Serum Profiling of Diabetes and Phosphoproteomics Analysis

    • Authors: Shi-Shu Yang, Yu-Jie Chang, Hao Zhang, Xizhong Yu, Wenbin Shang, Gui-Quan Chen, David Chen, Zhi-Yuan Gu
    • Year: 2018
  7. An Exfoliated 2D Egyptian Blue Nanosheet for Highly Selective Enrichment of Multi-phosphorylated Peptides in Mass Spectrometric Analysis

    • Authors: Shi-Shu Yang, Hai-Xia Yu, Zi-Zhen Wang, Hai-Long Liu, Hao Zhang, Xizhong Yu, Wenbin Shang, Gui-Quan Chen, Zhi-Yuan Gu
    • Year: 2018