Muhammad Farhat Ullah | Genetics and Molecular Biology | Best Researcher Award

Assist. Prof. Dr. Muhammad Farhat Ullah | Genetics and Molecular Biology | Best Researcher Award

University of Sialkot | Pakistan

Assist. Prof. Dr. Muhammad Farhat Ullah is a highly accomplished researcher and academic specializing in bioinformatics, molecular biology, forensic genomics, and population genetics. With over eight years of teaching and research experience, he has developed a reputation as an innovative scientist and dedicated mentor. He earned his Ph.D. in Bioinformatics from Quaid-i-Azam University Islamabad, where his research focused on genetic variability, population genomics, and computational biology. Currently serving as an Assistant Professor at the University of Sialkot (USKT), he combines advanced computational techniques with experimental biology to solve pressing biological and forensic problems. Dr. Ullah has made significant contributions to scientific literature with more than twenty peer-reviewed publications in prestigious journals indexed in Scopus and Web of Science. His works span diverse areas, including Y-STR mutation analysis, nanotechnology applications in biomedical sciences, population structure studies, and computational approaches to drug discovery. International collaborations with research groups in Italy, China, and the UAE highlight his global research presence. In addition to his scientific contributions, Dr. Ullah plays an active role in departmental leadership as Secretary of multiple academic committees and serves as a mentor for graduate and undergraduate students, promoting research excellence and innovation.

Professional Profile

Education

Assist. Prof. Dr. Muhammad Farhat Ullah academic journey reflects a consistent pursuit of excellence and interdisciplinary expertise. He began his higher education with a Bachelor of Science degree in Biotechnology from Gomal University, Dera Ismail Khan, Pakistan. During his undergraduate studies, he developed a strong foundation in molecular biology, genetics, and laboratory research techniques. He then pursued his Master of Science in Biotechnology at the International Islamic University Islamabad, where his thesis work focused on rationalization of pharmacotherapy in infectious diseases, giving him exposure to molecular diagnostics and applied biotechnology. Building upon this, he advanced to doctoral studies at Quaid-i-Azam University Islamabad, one of Pakistan’s leading research institutions. He completed his Ph.D. in Bioinformatics, with a dissertation centered on population genetics, mutational analysis of rapidly mutating Y-STRs, and computational biology approaches to genomic studies. His doctoral research combined statistical modeling, bioinformatics tools, and molecular analysis to address population-level genetic variations with forensic and biomedical implications. Throughout his academic career, Dr. Ullah has consistently demonstrated interdisciplinary expertise, blending wet-lab techniques with computational genomics. His educational achievements reflect a strong progression from biotechnology fundamentals to advanced computational bioinformatics, positioning him as a well-rounded scholar in life sciences.

Professional Experience

Assist. Prof. Dr. Muhammad Farhat Ullah currently serves as an Assistant Professor in the Department of Biological Sciences at the University of Sialkot, Pakistan. In this role, he teaches undergraduate and graduate courses in bioinformatics, molecular biology, and biotechnology, while supervising multiple MS and BS research theses. His teaching portfolio includes advanced bioinformatics, industrial biotechnology, biosafety, recombinant DNA technology, synthetic biology, and computational biology. Prior to his current role, Dr. Ullah worked as a Research Assistant and committee member at Quaid-i-Azam University Islamabad, where he gained hands-on experience with DNA extraction, PCR, gel electrophoresis, protein modeling, and next-generation sequencing analysis. He has also collaborated with international institutions on population genetics projects, including the Sapienza University of Rome in Italy, research centers in China, and police forensic units in Dubai. Beyond teaching and research, he holds leadership roles as Secretary of the Board of Studies, Curriculum Review Committee, and Industrial Advisory Board at USKT. His professional journey demonstrates a balance of academic instruction, research innovation, and administrative leadership. Through active mentorship, he is contributing to the development of the next generation of scientists while continuing to expand his global research collaborations.

Research Interests

Assist. Prof. Dr. Muhammad Farhat Ullah’s research interests are broad yet interconnected, reflecting his interdisciplinary training in biotechnology and bioinformatics. His primary focus lies in forensic genomics, where he investigates rapidly mutating Y-STRs and their applications in population genetics and forensic casework. He has contributed to understanding genetic diversity in Pakistani populations and collaborated with international groups to study Kohistani and Gilgiti populations, enhancing knowledge of South Asian genetic history. In addition, he explores bioinformatics-driven approaches for drug discovery and development, employing computational tools to model proteins, analyze mutations, and identify molecular targets. His work also extends to nanotechnology, where he evaluates nanoparticles and nanocomposites for biomedical and environmental applications, such as photocatalysis and drug delivery. Dr. Ullah has also been actively engaged in pandemic-related research, including the use of CRISPR/Cas9 technology in COVID-19 treatment strategies. He is equally passionate about population genomics, mitochondrial genomics, and exome sequencing, integrating advanced statistical methods with molecular data. His multidisciplinary research interests demonstrate his commitment to applying computational biology in solving real-world problems in healthcare, forensic science, and environmental sustainability. This fusion of molecular experimentation and computational analysis positions him at the cutting edge of modern life sciences research.

Research Skills

Assist. Prof. Dr. Muhammad Farhat Ullah possesses a diverse skill set that integrates both laboratory-based molecular biology techniques and advanced computational bioinformatics tools. His experimental expertise includes DNA extraction, PCR amplification, gel electrophoresis, polyacrylamide gel electrophoresis, Sanger sequencing, and capillary electrophoresis using Applied Biosystems Genetic Analyzers (310 and 3100). He is skilled in STR biomarker analysis, including Y-STRs and rapidly mutating STRs, which are widely applied in forensic genetics and population studies. On the computational side, he has extensive experience with whole exome sequencing analysis, protein modeling, primer designing, and in-silico mutational analysis. He is proficient in statistical data analysis using MATLAB (R2022b) and multiple bioinformatics software platforms for gene scanning, genotyping, and protein structure evaluations. His technical expertise further extends to nanotechnology characterization techniques, computational drug discovery, and modeling of genetic variations. In addition, Dr. Ullah has strong skills in teaching and mentoring, supervising student projects involving computational genomics, SNP analysis, and phylogenetic studies. His ability to bridge wet-lab and dry-lab skills makes him a versatile scientist, capable of handling diverse research projects. By combining hands-on experimental knowledge with computational proficiency, Dr. Ullah contributes to advancing molecular biology, forensic science, and biomedical applications.

Awards and Honors

Assist. Prof. Dr. Muhammad Farhat Ullah has received recognition for his academic achievements, research contributions, and leadership roles. During his Ph.D., he was awarded the prestigious IRSIP fellowship by the Higher Education Commission (HEC) of Pakistan, which enabled him to undertake an international research internship at the Sapienza University of Rome, Italy. This fellowship provided him with exposure to cutting-edge genetic research methodologies and allowed him to collaborate with world-renowned population geneticists. At the University of Sialkot, he has been entrusted with significant academic leadership responsibilities, including serving as Secretary of the Board of Studies, Curriculum Review Committee, and Industrial Advisory Board within the Department of Biological Sciences. His professional achievements also include active participation in international collaborations with institutions in China, Dubai, and Italy, contributing to projects on population genetics, forensic applications of Y-STRs, and mitochondrial genomics. In addition to formal recognition, he has built a strong publication record in high-impact journals, which reflects his growing influence in the scientific community. These achievements, coupled with his dedication to student mentorship and research advancement, demonstrate his standing as an emerging leader in bioinformatics and molecular genetics at both national and international levels.

Publication Top Notes

  • Population and mutational assessment of novel repeats in 13RM Y-STRs in unrelated males born in Gilgit, Pakistan — 2022

  • Novel heterozygous frameshift mutation in distal-less homeobox 5 underlies isolated split hand/foot malformation type 1 — 2016

  • Evaluation of rapidly mutating Y-STRs in Pakistani population — 2019

  • A review of COVID-19: Treatment strategies and CRISPR/Cas9 gene editing technology approaches to the coronavirus disease — 2021

  • Biosynthesis of silver nanoparticles from novel Bischofia javanica plant loaded chitosan hydrogel: as antimicrobial and wound healing agent — 2022

  • Structural Evaluation and Conformational Dynamics of ZNF141T474I Mutation Provoking Postaxial Polydactyly Type A — 2022

  • RM-plex kit to analyze 130 father-son pairs from Gilgit Baltistan region of Pakistan at 13 RM Y-STR loci, producing unique mutation data and merging it with previously reported mutation data.

Conclusion

In conclusion, Assist. Prof. Dr. Muhammad Farhat Ullah exemplifies the qualities of an outstanding researcher, academic leader, and mentor. His educational foundation in biotechnology and bioinformatics, coupled with his extensive research in forensic genomics, computational biology, and nanotechnology, positions him as a versatile and impactful scholar. With more than twenty international publications, several collaborative projects, and active involvement in student supervision, he has significantly contributed to advancing knowledge in population genetics, forensic casework, and biomedical applications. His IRSIP fellowship experience in Italy and collaborations with global institutions reflect his ability to integrate international expertise into local research contexts, thereby strengthening Pakistan’s presence in the global scientific arena. Dr. Ullah’s technical proficiency, innovative research approaches, and dedication to teaching make him a role model for aspiring scientists. Moving forward, his commitment to expanding Q1 publications, engaging in editorial responsibilities, and pursuing broader global collaborations will further enhance his academic footprint. With proven leadership at his institution and a growing international reputation, Dr. Ullah has the potential to become a leading figure in bioinformatics and molecular sciences. His contributions to science and education make him a deserving candidate for recognition at the international level.

Paul Cullen | Genetics | Best Researcher Award

Dr. Paul Cullen | Genetics | Best Researcher Award

Doctorate at University at Buffalo, United States

Dr. Paul Cullen is a Professor in the Department of Biological Sciences at the University at Buffalo, specializing in molecular genetics and cell biology. He completed his postdoctoral training at the Institute of Molecular Biology at the University of Oregon, where he worked on MAP kinase (MAPK) signaling pathways, funded by grants from the American Heart Association and the National Institutes of Health (NIH). Dr. Cullen earned his Ph.D. in Molecular Genetics from Washington University in Saint Louis, where his research focused on bacterial nitrogen control proteins. He holds a Bachelor of Science in Biological Sciences from the University of Illinois at Urbana-Champaign, graduating Magna Cum Laude with Distinction. Dr. Cullen’s research interests revolve around understanding the regulation of cellular differentiation and signaling pathways, particularly in yeast. He has received numerous accolades, including the UB Exceptional Scholar’s Award and the Distinguished Postdoc Mentor Award. His work is supported by multiple NIH grants, and he has contributed significantly to the scientific community through publications and mentorship.

Education

Dr. Paul Cullen holds an impressive educational background in the field of biological sciences and molecular genetics. He earned his Bachelor of Science degree in Biological Sciences from the University of Illinois, Urbana-Champaign, graduating Magna Cum Laude with Distinction in 1990. His undergraduate thesis, titled “Effect of Ecdysone on In Vitro Pupal Wing Development in Lepidoptera,” was conducted under the supervision of Dr. Judith Willis and Dr. Johnathan Widom. Following this, Dr. Cullen pursued his Doctor of Philosophy (Ph.D.) in Molecular Genetics at Washington University, Saint Louis, completing his degree in 1997. His Ph.D. research, titled “Bacterial Nitrogen Control Proteins,” was guided by Dr. Robert G. Kranz. Additionally, from 1998 to 2004, Dr. Cullen completed postdoctoral training at the Institute of Molecular Biology at the University of Oregon, under the mentorship of Dr. George F. Sprague, Jr. His postdoctoral work was supported by prestigious grants from the American Heart Association and the National Institutes of Health (NIH), further solidifying his expertise in molecular biology.

Professional Experience

Dr. Paul Cullen has held a series of prestigious academic and research positions throughout his career. He is currently a Professor in the Department of Biological Sciences at the University at Buffalo, where he has been a faculty member since 2004. Prior to his promotion to Professor in 2017, Dr. Cullen served as an Associate Professor from 2010 to 2017 and as an Assistant Professor from 2004 to 2010. He has also held a joint appointment as Clinical Research Assistant Professor in the Department of Microbiology and Immunology since 2005. Earlier in his career, Dr. Cullen was a Senior Research Fellow at the Institute of Molecular Biology at the University of Oregon from 2000 to 2004. He has also contributed to scientific review panels, including serving as an NIH Review Panelist for Eukaryotic Pathogens in 2024. In addition to his research, Dr. Cullen has been deeply involved in academic administration, serving as the Director of Graduate Affairs for the Department of Biological Sciences from 2019 to 2024 and as a member of the Graduate School Executive Committee from 2023 to 2024.

Research Interest

Dr. Paul Cullen’s research interests focus on understanding the molecular mechanisms that regulate cellular differentiation, particularly through MAP kinase (MAPK) signaling pathways. His work explores how these pathways control cellular responses to environmental cues, with a special emphasis on the filamentous growth of Saccharomyces cerevisiae (yeast). Dr. Cullen investigates the role of cell polarity proteins in modulating MAPK signaling and how regulatory proteins influence these pathways. His research also extends to studying signal transduction in various biological systems, aiming to uncover broader implications for cellular behavior and development in eukaryotic organisms. Through his work, Dr. Cullen seeks to advance knowledge of genetic and molecular processes that underpin complex biological responses, contributing to the fields of molecular genetics, cell biology, and microbiology.

Research Skills

Dr. Paul Cullen possesses extensive research skills in molecular genetics and cell biology, particularly in the regulation of MAP kinase (MAPK) signaling pathways. His expertise includes advanced molecular techniques such as gene manipulation, protein-protein interaction studies, and genetic screening in model organisms like Saccharomyces cerevisiae. Dr. Cullen is skilled in using molecular and genetic tools to investigate cellular differentiation, signal transduction, and environmental response mechanisms. He has a strong background in high-throughput screening, microscopy, and quantitative data analysis. His research also involves cutting-edge technologies in genetic sequencing, bioinformatics, and structural biology, contributing to his deep understanding of cellular signaling networks and their implications for health and disease.

Award and Recognition

Dr. Paul Cullen has received numerous accolades for his exemplary contributions to research and education. In 2023, he was honored with the UB Exceptional Scholar’s Award for Sustained Achievement and the UB Graduate School Distinguished Postdoc Mentor Award, recognizing his significant impact in mentorship. Additionally, he received the Milton Plesur Excellence in Teaching Award in 2008 for his dedication to student learning. His active membership in professional organizations such as the American Society of Cell Biology and the American Society of Microbiology further highlights his commitment to advancing the field of molecular biology.

Conclusion

Dr. Paul Cullen’s remarkable achievements in molecular biology, sustained research contributions, and commitment to mentoring make him a distinguished figure in his field. His combination of academic excellence, leadership, and impactful research positions him as an exemplary candidate for the “Research for Best Researcher Award.”

Publication Top Notes

  • “Glucose depletion causes haploid invasive growth in yeast”
    • Journal: Proceedings of the National Academy of Sciences
    • Cited by: 444
    • Year: 2000
    • Volume: 97, Issue 25
    • Pages: 13619-13624
  • “The regulation of filamentous growth in yeast”
    • Journal: Genetics
    • Cited by: 348
    • Year: 2012
    • Volume: 190, Issue 1
    • Pages: 23-49
  • “A signaling mucin at the head of the Cdc42-and MAPK-dependent filamentous growth pathway in yeast”
    • Journal: Genes & Development
    • Cited by: 268
    • Year: 2004
    • Volume: 18, Issue 14
    • Pages: 1695-1708
  • “GTPase-activating proteins for Cdc42”
    • Journal: Eukaryotic Cell
    • Cited by: 170
    • Year: 2002
    • Volume: 1, Issue 3
    • Pages: 469-480
  • “Defects in Protein Glycosylation Cause SHO1-Dependent Activation of a STE12 Signaling Pathway in Yeast”
    • Journal: Genetics
    • Cited by: 147
    • Year: 2000
    • Volume: 155, Issue 3
    • Pages: 1005-1018
  • “Cleavage of the signaling mucin Msb2 by the aspartyl protease Yps1 is required for MAPK activation in yeast”
    • Journal: The Journal of Cell Biology
    • Cited by: 144
    • Year: 2008
    • Volume: 181, Issue 7
    • Pages: 1073-1081
  • “Secreted aspartic protease cleavage of Candida albicans Msb2 activates Cek1 MAPK signaling affecting biofilm formation and oropharyngeal candidiasis”
    • Journal: PLoS One
    • Cited by: 112
    • Year: 2012
    • Volume: 7, Issue 11
    • Pages: e46020
  • “Candida albicans biofilm development is governed by cooperative attachment and adhesion maintenance proteins”
    • Journal: NPJ Biofilms and Microbiomes
    • Cited by: 111
    • Year: 2019
    • Volume: 5, Issue 1
    • Pages: 21