Ronit Satchi-Fainaro | Pharmacology | Outstanding Scientist Award

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Prof Dr. Ronit Satchi-Fainaro | Pharmacology | Outstanding Scientist Award

 Cancer Biology Research Center at Tel Aviv University, Israel

Ronit Satchi-Fainaro is a prominent figure in cancer research, currently serving as a Full Professor in the Department of Physiology and Pharmacology at Tel Aviv University and Director of the Cancer Biology Research Center. With a Ph.D. in polymer chemistry and extensive postdoctoral training at renowned institutions, her research focuses on cancer biology, tumor dormancy, and the development of targeted nanomedicines. Satchi-Fainaro has pioneered multi-modality polymer therapeutics that combine anti-angiogenic agents with chemotherapeutics, significantly advancing the field of cancer treatment. Her impressive publication record includes groundbreaking articles in Nature Medicine and Cancer Cell, and she has filed multiple patents for her innovative findings. Additionally, she has received numerous accolades for her contributions to science, including the Humboldt Foundation Bessel Research Prize. Satchi-Fainaro’s leadership in interdisciplinary research and commitment to translating scientific discoveries into clinical applications make her a leading voice in modern cancer therapeutics.

Professional Profile

Education

Ronit Satchi-Fainaro has an impressive educational background that laid the foundation for her distinguished career in pharmacology and cancer research. She earned her Bachelor of Pharmacy (B.Pharm.) degree in Pharmacology from The Hebrew University, Faculty of Medicine, School of Pharmacy, in June 1995. Following her undergraduate studies, she completed an internship in Industrial Pharmacy at Perio Products Ltd. in Jerusalem in March 1996. Satchi-Fainaro then pursued her Ph.D. at the University of London, specializing in polymer chemistry, biochemistry, and cancer nanomedicine. Her doctoral research, titled “PDEPT: Polymer Directed Enzyme Prodrug Therapy,” was completed in November 1999 under the supervision of Prof. Ruth Duncan. Subsequently, she expanded her expertise through postdoctoral fellowships at Tel Aviv University and Harvard Medical School, focusing on tumor biology, molecular biology, and protein delivery, further solidifying her status as a leader in the field of cancer research and nanomedicine.

 

Professional Experience

Ronit Satchi-Fainaro is a distinguished Full Professor in the Department of Physiology and Pharmacology at Tel Aviv University and serves as the Director of the Cancer Biology Research Center. With over 15 years of leadership at the university, she has spearheaded a multidisciplinary research group focused on innovative cancer therapies. Satchi-Fainaro’s expertise encompasses polymer chemistry, biochemistry, and nanomedicine, leading to the development of targeted polymer therapeutics and nano-vaccines. She has collaborated with prominent institutions, including Harvard Medical School, where she contributed to significant advances in tumor biology and angiogenesis. Her entrepreneurial spirit is evident through her co-founding of biotech companies, such as ImmuNovation, Ltd., and her active role on various scientific advisory boards. Satchi-Fainaro has garnered numerous accolades, including the Humboldt Foundation Bessel Research Prize, reflecting her substantial impact in cancer research and drug delivery systems. Her work continues to push the boundaries of personalized medicine and cancer therapeutics

Research Interests

Ronit Satchi-Fainaro’s research interests lie at the intersection of cancer biology, pharmacology, and nanomedicine. She focuses on understanding the mechanisms underlying cancer dormancy and the tumor-host interactions that facilitate metastasis. Her innovative work involves developing targeted nanomedicines that integrate anti-stromal agents with chemotherapeutics to enhance treatment efficacy while reducing toxicity. Satchi-Fainaro’s laboratory employs advanced techniques such as molecular imaging, 3D bioprinted cancer models, and personalized theranostics to investigate tumor biology and angiogenesis. She aims to identify molecular signatures that predict tumor behavior and survivorship, driving the rational design of novel therapeutic approaches. Additionally, her interdisciplinary approach combines elements of biology, chemistry, engineering, and material sciences, facilitating the development of highly selective drug delivery systems. Through her pioneering research, Satchi-Fainaro aspires to contribute to more effective cancer therapies and improve patient outcomes in the fight against cancer.

Ronit Satchi-Fainaro has received numerous prestigious awards and honors throughout her distinguished career, reflecting her significant contributions to cancer research and nanomedicine. Notable accolades include the British Council Chevening Award, the Nagai Foundation Graduate Student Award, and the Fulbright Scholarship. She was recognized as a “Person of the Year” in Medicine by Forbes Israel and included in various influential lists, such as the “50 Most Influential Women” and “40 Under 40” by prominent Israeli journals. In addition, she has received the ERC Advanced Grant, the 3D Printing Industry Award for Medical Application of the Year, and the Bessel Research Prize from the Humboldt Foundation. Her work has garnered multiple research prizes for exceptional publications at Tel Aviv University and recognition as a Fellow of the American Institute of Medical and Biological Engineers (AIMBE). These accolades highlight her impactful research and leadership in advancing innovative cancer therapies.

 

Conclusion

Ronit Satchi-Fainaro is a distinguished leader in cancer research, whose innovative work in nanomedicine has significantly advanced the understanding and treatment of cancer. With a robust academic background and over 15 years at Tel Aviv University, she has successfully led multidisciplinary research initiatives that tackle complex questions in tumor biology and drug delivery. Her pioneering development of multi-modality targeted nanomedicines has not only garnered numerous patents but also positioned her at the forefront of translational research. Satchi-Fainaro’s impressive publication record in high-impact journals, coupled with her numerous accolades—including the Humboldt Foundation Bessel Research Prize—underscores her contributions to science. As the Director of the Cancer Biology Research Center, she exemplifies a commitment to fostering collaboration and mentorship in the scientific community. Overall, her accomplishments and dedication to improving cancer therapies make her a highly deserving candidate for the Research for Outstanding Scientist Award.

 

Publication top noted
  • Title: interFLOW: maximum flow framework for the identification of factors mediating the signaling convergence of multiple receptors
    Authors: Sheinin, R., Salomon, K., Yeini, E., Sharan, R., Madi, A.
    Year: 2024
    Citations: 0
  • Title: Polyester nanoparticles delivering chemotherapeutics: Learning from the past and looking to the future to enhance their clinical impact in tumor therapy
    Authors: Longobardi, G., Moore, T.L., Conte, C., Satchi-Fainaro, R., Quaglia, F.
    Year: 2024
    Citations: 0
  • Title: Multifunctional Nanovaccine Sensitizes Breast Cancer to Immune Checkpoint Therapy
    Authors: Peres, C., Matos, A.I., Carreira, B., Satchi-Fainaro, R., Florindo, H.F.
    Year: 2024
    Citations: 2
  • Title: Combining TIGIT Blockade with MDSC Inhibition Hinders Breast Cancer Bone Metastasis by Activating Antitumor Immunity
    Authors: Monteran, L., Ershaid, N., Scharff, Y., Zhang, X.H.-F., Erez, N.
    Year: 2024
    Citations: 3
  • Title: The role of CCL2/CCR2 axis in cancer and inflammation: The next frontier in nanomedicine
    Authors: Pozzi, S., Satchi-Fainaro, R.
    Year: 2024
    Citations: 3
  • Title: Potent antitumor activity of anti-HER2 antibody-topoisomerase I inhibitor conjugate based on self-immolative dendritic dimeric-linker
    Authors: Liubomirski, Y., Tiram, G., Scomparin, A., Shabat, D., Satchi-Fainaro, R.
    Year: 2024
    Citations: 3
  • Title: Intranasal Multiepitope PD-L1-siRNA-Based Nanovaccine: The Next-Gen COVID-19 Immunotherapy
    Authors: Acúrcio, R.C., Kleiner, R., Vaskovich-Koubi, D., Florindo, H.F., Satchi-Fainaro, R.
    Year: 2024
    Citations: 0
  • Title: Polyoxazoline-Based Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and Anti-PD-1 Immunotherapy against Solid Tumors
    Authors: Matos, A.I., Peres, C., Carreira, B., Satchi-Fainaro, R., Florindo, H.F.
    Year: 2023
    Citations: 6
  • Title: Deoxyhypusine hydroxylase: A novel therapeutic target differentially expressed in short-term vs long-term survivors of glioblastoma
    Authors: Ofek, P., Yeini, E., Arad, G., Geiger, T., Satchi-Fainaro, R.
    Year: 2023
    Citations: 4
  • Title: Development of Chitosan Particles Loaded with siRNA for Cystatin C to Control Intracellular Drug-Resistant Mycobacterium tuberculosis
    Authors: Pires, D., Mandal, M., Matos, A.I., Florindo, H.F., Anes, E.
    Year: 2023
    Citations: 6

Bashige Chiribagula Valentin | Pharmaceutical Science | Best Researcher Award

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Prof. Bashige Chiribagula Valentin | Pharmaceutical Science | Best Researcher Award

Professor of UNILU, Congo.

Dr. Bashige Chiribagula Valentin is a prominent academic and researcher specializing in ethnopharmacology, medicinal chemistry, and quality control. Currently a professor at the University of Lubumbashi, he has held roles including department head, research specialist in pharmacognosy, and educator in pharmacology. His research focuses on the ethnobotanical, phytochemical, and pharmacological properties of medicinal plants, with significant contributions to the development of traditional medicine-based therapies, such as antimalarial and antimicrobial agents. Dr. Chiribagula has led various projects aimed at enhancing the quality and efficacy of herbal remedies and has published extensively in reputed journals. His work includes studies on plant-based treatments for malaria, diabetes, and wound healing, reflecting his commitment to integrating traditional knowledge with modern scientific approaches. His leadership in the academic and scientific community, coupled with his impactful research, underscores his candidacy for the Best Researcher Award.

Profile
Education

Dr. Bashige Chiribagula Valentin’s educational background is extensive and well-rounded. He earned his Doctorate in Pharmaceutical Sciences from the University of Lubumbashi (UNILU) and the Université de Mons (UMONS) in 2021, specializing in Pharmacognosy with a focus on ethnopharmacology. Prior to this, he obtained a Diplôme d’Études Approfondies in Pharmacognosy from UNILU in 2016. His foundational education includes a Diplôme de Pharmacie d’Industrie et Analyse de Médicaments from UNILU, completed in 2012, and a Diplôme d’Études Générales en Sciences Pharmaceutiques from the University of Kinshasa (UNIKIN) in 2006. His academic journey demonstrates a strong commitment to advancing knowledge in pharmaceutical sciences, particularly in the areas of pharmacognosy and ethnopharmacology.

Professional Experience

Dr. Bashige Chiribagula Valentin has an extensive and diverse professional background in the field of pharmacognosy and ethnopharmacology. He has served as a Professor at the University of Lubumbashi since 2022, where he also holds positions as President of juries and Secretary of the Department of Pharmacology. His career at the university began as an Assistant in 2013, progressing to a Chief of Works and Specialist in Pharmacognosy. In addition to his academic roles, Dr. Chiribagula has been actively involved in the pharmaceutical industry as a Quality Control Manager at PROMED Lubumbashi. His research focuses on ethnopharmacology, medicinal chemistry, and quality control of medicinal plants, contributing significantly to the development of traditional medicine projects. Dr. Chiribagula’s career also includes roles in secondary education and civil society, showcasing his dedication to both education and community service.

Research Interest

Dr. Bashige Chiribagula Valentin’s research focuses on the ethnopharmacological and medicinal properties of plants, particularly in the context of traditional medicine. His work spans the study of plant-based remedies for various diseases, including malaria and diabetes, with a strong emphasis on the pharmacognosy of medicinal plants. Dr. Chiribagula’s research integrates ethnobotanical surveys, phytochemical analysis, and pharmacological testing to explore and validate the therapeutic potential of natural substances. His projects include the development of medicinal plants for wound healing, anti-malarial, anti-ulcer, and antibacterial applications. Additionally, he investigates the nutritional and medicinal benefits of indigenous fungi, fruits, and vegetables. His research aims to bridge traditional knowledge with modern scientific validation, contributing to the development of effective, natural therapeutic agents and enhancing the quality of life in the Democratic Republic of Congo.

Research Skills

Dr. Bashige Chiribagula Valentin demonstrates a robust set of research skills essential for advancing his field of study. His expertise spans ethnopharmacology, medicinal chemistry, and quality control, with a strong emphasis on the pharmacognostic and phytochemical evaluation of medicinal plants. Dr. Chiribagula excels in employing various analytical techniques, including chromatography (TLC, Flash, HPLC), spectral analysis (MS), and microbiological assays (antimicrobial testing, antioxidant assays). His proficiency in using statistical software such as SPSS and GraphPad supports his rigorous data analysis. Additionally, he has a solid background in experimental design and execution, demonstrated by his work on traditional medicine and natural product research. His ability to integrate traditional knowledge with scientific methodologies underscores his contributions to the development of novel therapeutic agents and quality control measures in pharmaceuticals. Dr. Chiribagula’s comprehensive approach and methodological skills are integral to his research successes.

Awards and Recognition

Dr. Bashige Chiribagula Valentin has garnered significant recognition for his contributions to pharmacognosy and ethnopharmacology. He was honored as the “Major de Promotion” in 2012 and achieved notable accolades in 2019, securing first place at the MT180 regional AUF competition and second place at the national MT180 competition. His scholarly excellence is highlighted by his award-winning research on ethnobotanical studies and medicinal plants, which has been recognized in several prestigious journals. Dr. Chiribagula’s impactful work in the development of medicinal plant-based treatments, including those for malaria and wound healing, has further solidified his reputation in the scientific community. These awards underscore his dedication to advancing knowledge in pharmaceutical sciences and his commitment to improving public health through innovative research.

Conclusion

Bashige Chiribagula Valentin is a strong candidate for the Research for Best Researcher Award due to his substantial contributions to ethnopharmacology, his significant publications, and his active role in academia and the pharmaceutical industry. His expertise in traditional medicine and his impactful research on medicinal plants, coupled with his notable awards and professional experience, underline his qualifications for the award.

Publications Top Notes

  • Ethnomedical Knowledge of Plants Used in Nonconventional Medicine for Wound Healing in Lubumbashi, Haut‐Katanga Province, DR Congo
    • Authors: Bashige Chiribagula Valentin
    • Year: 2024
  • Ethnomedicinal Knowledge of Plants Used in Nonconventional Medicine in the Management of Diabetes Mellitus in Kinshasa (Democratic Republic of the Congo)
    • Authors: Bashige Chiribagula Valentin
    • Year: 2023
  • Ethnobotanical study of plants used by traditional healers in Lubumbashi (Democratic Republic of Congo) in the management of typhoid fever
    • Authors: Bashige Chiribagula Valentin
    • Year: 2022
  • Activité antioxydante de 53 plantes réputées antimalariques en République Démocratique du Congo
    • Authors: Bashige Chiribagula Valentin
    • Year: 2021
  • In vitro antioxidant activity and in vivo aphrodisiac activity in male Cavia porcellus of Albizia adianthifolia (Schum.) W. Wight and Pericopsis angolensis (Baker) Meeuwen
    • Authors: Bashige Chiribagula Valentin
    • Year: 2021
  • Knowledge, attitudes and practices among the population, towards COVID-19 in the Lubumbashi city (DR Congo): An online cross-sectional survey
    • Authors: Bashige Chiribagula Valentin
    • Year: 2021
  • Mineral elements analysis and total flavonoids content in the fresh leaves from two varieties of Hibiscus sabdariffa L. consumed as vegetable in Lubumbashi (DR Congo)
    • Authors: Bashige Chiribagula Valentin
    • Year: 2021
  • Antimicrobial, antioxidant activities and toxicity on Cavia porcellus of Dialium angolense Welw. Ex Oliv, a traditional medicinal plant from Bagira in Eastern of DR Congo
    • Authors: Bashige Chiribagula Valentin
    • Year: 2020
  • Ethnobotanical study of medicinal plants used in the treatment of sexual dysfunctions in traditional medicine in Kampemba-Lubumbashi, DR Congo
    • Authors: Bashige Chiribagula Valentin
    • Year: 2020
  • Antiplasmodial, antioxidant and toxicological study of leaves extracts of Dalbergia katangensis Lecheneaud (Fabaceae) from Eastern DR Congo
    • Authors: Bashige Chiribagula Valentin
    • Year: 2020