Prof. Xiao Yang | Materials Science | Best Researcher Award
Professor at Sichuan University, China
Professor Xiao Yang is a distinguished scholar in biomedical engineering, specializing in the development of biomaterials and implantable medical devices for the musculoskeletal system. Her research primarily focuses on calcium phosphate-based bioceramics and functionalized implants designed to repair diseased bone, particularly in conditions such as osteoporosis and osteosarcoma. As a core member of Professor Xingdong Zhang’s research group at the National Engineering Research Center for Biomaterials, Sichuan University, she has made significant contributions to understanding cellular interactions between host tissues and implants. Her work aims to enhance the integration and functionality of medical devices within the human body, thereby improving patient outcomes.
Professional Profile
Education
Professor Yang’s academic journey commenced with a Bachelor’s degree in Biotechnology from Wuhan University of Technology, completed between 2004 and 2008. She then pursued her doctoral studies at the National University of Singapore, earning a Ph.D. in Bioengineering in 2013. Her doctoral research laid a robust foundation in biomedical engineering, equipping her with the expertise necessary for her subsequent endeavors in biomaterials and medical device innovation. This comprehensive educational background has been instrumental in shaping her research trajectory and academic career.
Professional Experience
Following her Ph.D., Professor Yang embarked on a postdoctoral fellowship in the Department of Pharmacology at the Yong Loo Lin School of Medicine from 2013 to 2014. In 2014, she joined Sichuan University as an Associate Professor at the National Engineering Research Center for Biomaterials. Over the next decade, her dedication and contributions to the field were recognized with a promotion to full Professor in 2023. Throughout her tenure, she has been an integral part of Professor Xingdong Zhang’s research team, where she continues to advance the development of innovative biomaterials and implantable devices.
Research Interests
Professor Yang’s research interests are deeply rooted in the development of advanced biomaterials and implantable medical devices tailored for the musculoskeletal system. She has a particular focus on engineering calcium phosphate-based bioceramics and creating functionalized implants aimed at repairing bones affected by diseases such as osteoporosis and osteosarcoma. Additionally, her work explores the intricate cellular interactions between host tissues and implants, striving to improve biocompatibility and the overall success of implant integration. Her research endeavors are driven by a commitment to translating scientific discoveries into clinical applications that enhance patient care.
Research Skills
Throughout her career, Professor Yang has honed a diverse set of research skills that underpin her scientific contributions. She possesses expertise in biomechanics, with a focus on analyzing viscoelastic properties at both macro and micro levels, which is crucial for understanding the mechanical behavior of biomaterials. Her proficiency in medical imaging, particularly 3D reconstruction techniques, facilitates the precise design and assessment of implantable devices. Moreover, she has substantial experience in the fabrication of bioceramics and investigating their osteoinductive mechanisms, contributing to advancements in bone disease treatments and the development of more effective therapeutic strategies.
Awards and Honors
In recognition of her innovative research, Professor Yang has secured several significant grants as Principal Investigator over the past five years. In 2023, she was awarded funding from the National Key Research and Development Program of China. The previous year, she received a grant for developing PLA/nano-hydroxyapatite composite materials for craniofacial bone repair. In 2020, her work on bioceramics with anti-tumor and tissue regeneration functions was recognized with a key research and development program grant from Sichuan Province. These accolades underscore her leadership and pioneering contributions to the field of biomedical engineering.
Conclusion
Professor Xiao Yang’s extensive education, professional experience, and research expertise have established her as a leading figure in biomedical engineering. Her unwavering dedication to developing advanced biomaterials and implantable devices has significantly impacted treatments for musculoskeletal disorders. Through her innovative research and numerous contributions to the scientific community, Professor Yang continues to advance the field, setting new standards in biomedical engineering and improving patient outcomes worldwide.
Publication Top Notes
- “Antheraea pernyi silk nanofibrils with inherent RGD motifs accelerate diabetic wound healing: A novel drug-free strategy to promote hemostasis, regulate immunity and improve re-epithelization”
- Authors: Lian Duan, Ga Liu, Fuying Liao, Chunyu Xie, Subhas C. Kundu, Bo Xiao
- Year: 2025
- Journal: Biomaterials
- DOI: 10.1016/j.biomaterials.2025.123127
- “Antibacterial cationic porous organic polymer coatings via an adsorption-contact-photodynamic inactivation strategy for treatment of drug-resistant bacteria”
- Authors: Lingshuang Wang, Jiahao Shi, Shengfei Bao, Ga Liu, Chunyu Xie, Fuying Liao, Subhas C. Kundu, Rui L. Reis, Lian Duan, Bo Xiao, Xiao Yang
- Year: 2025
- Journal: Journal of Colloid and Interface Science
- DOI: 10.1016/j.jcis.2024.09.242
- “Piezoelectric Biomaterial with Advanced Design for Tissue Infection Repair”
- Authors: Siyuan Shang, Fuyuan Zheng, Wen Tan, Xingdong Zhang, Xiao Yang
- Year: 2025
- Journal: Advanced Science
- “Advancements in nanohydroxyapatite: synthesis, biomedical applications and composite developments”
- Authors: Rui Zhao, Xiang Meng, Zixian Pan, Xiao Yang, Xingdong Zhang
- Year: 2025
- Journal: Regenerative Biomaterials
- “3D-Printed custom-made hemipelvic endoprosthetic reconstruction following periacetabular tumor resection: utilizing a novel classification system”
- Authors: Xin Hu, Minxun Lu, Yitian Wang, Li Min, Chongqi Tu
- Year: 2024
- Journal: BMC Musculoskeletal Disorders
- “Biomechanical and clinical outcomes of 3D-printed versus modular hemipelvic prostheses for limb-salvage reconstruction following periacetabular tumor resection: a mid-term retrospective cohort study”
- Authors: Xin Hu, Yang Wen, Minxun Lu, Chongqi Tu, Li Min
- Year: 2024
- Journal: Journal of Orthopaedic Surgery and Research
- “Enhancing melanoma therapy by modulating the immunosuppressive microenvironment with an MMP-2 sensitive and nHA/GNE co-encapsulated hydrogel”
- Authors: Zhu Chen, Hongfeng Wu, Yifu Wang, Xiangdong Zhu, Xingdong Zhang
- Year: 2024
- Journal: Acta Biomaterialia
- “Advancing Osteoporotic Bone Regeneration Through Tailored Tea Polyphenols Functionalized Micro-/Nano-Hydroxyapatite Bioceramics”
- Authors: Rui Zhao, Hui Qian, Xiangdong Zhu, Zhenhua Chen, Xiao Yang
- Year: 2024
- Journal: Advanced Functional Materials
- “Harnessing the power of hydroxyapatite nanoparticles for gene therapy”
- Authors: Zhengyi Xing, Siyu Chen, Zhanhong Liu, Xiangdong Zhu, Xingdong Zhang
- Year: 2024
- Journal: Applied Materials Today
- “Auxetic Biomedical Metamaterials for Orthopedic Surgery Applications: A Comprehensive Review”
- Authors: Minghao Sun, Xin Hu, Leilei Tian, Xiao Yang, Li Min
- Year: 2024
- Journal: Orthopaedic Surgery