Michael Welsh | Genetics and Molecular Biology | Best Researcher Award

Published on by Shen Awards

Prof. Michael Welsh |Genetics and Molecular Biology | Best Researcher Award

Uppsala University, Sweden

Professor J. Michael Welsh is an internationally recognized biomedical scientist renowned for his pioneering research in the field of medical cell biology, particularly focusing on cystic fibrosis, epithelial ion transport, and pulmonary disease mechanisms. As a leading figure in translational medicine, Professor Welsh has made groundbreaking discoveries that have reshaped the global understanding of cystic fibrosis pathophysiology, contributing directly to the development of therapeutic strategies that have improved patient outcomes worldwide. His research has centered on the molecular and cellular basis of epithelial ion channel dysfunction, elucidating the mechanisms by which CFTR gene mutations cause abnormal chloride transport and disrupted mucociliary clearance in the airways. Throughout his distinguished career, Professor Welsh has authored over 610 peer-reviewed publications, accumulating more than 62,725 citations and achieving an h-index exceeding 130, underscoring his far-reaching influence in the biomedical community. His scholarly excellence and innovation have earned him election to the U.S. National Academy of Sciences and the National Academy of Medicine, reflecting his standing as one of the foremost authorities in molecular physiology and genetics. In addition to his scientific achievements, Professor Welsh has demonstrated exemplary leadership as the founder of the University of Iowa Cystic Fibrosis Research Center, fostering cross-disciplinary collaborations with clinicians, geneticists, and pharmaceutical scientists to accelerate the translation of basic research into clinical applications. Professor Welsh’s research has profoundly influenced not only molecular medicine but also public health, by shaping therapeutic approaches that extend life expectancy and quality of life for individuals affected by genetic and respiratory diseases. His mentorship of emerging scientists and his commitment to collaborative, patient-centered innovation exemplify his enduring contribution to science and society. Through his visionary work, Professor Welsh continues to bridge the gap between molecular discovery and clinical transformation, embodying the essence of global scientific excellence and impact.

Profiles: Scopus | ORCID

Featured Publications

  1. Celis, N., Miller, D. P., Tarara, T. E., Weers, J. G., Thornell, I. M., Welsh, M. J., & Burke, M. D. (2025). Molecular prosthetics and CFTR modulators additively increase secretory HCO3− flux in cystic fibrosis airway epithelia. bioRxiv.

  2. Welsh, M. J. (2025, September 11). Rewriting the chapter on cystic fibrosis. JAMA.

  3. Welsh, M. J. (2025, August 10). A dose-finding study shows terazosin enhanced energy metabolism in neurologically healthy adults. Journal of Parkinson’s Diseases.

  4. Thornell, I. M., Lei, L., McCray, P. B. Jr., & Welsh, M. J. (2025). Do pulmonary ionocytes absorb chloride or secrete chloride? American Journal of Physiology-Cell Physiology.

  5. Karp, P., Welsh, M., Kim, B. R., Keen, H., Rauckhorst, A. J., Taylor, E. B., Chimenti, M. S., & Rehman, T. (2025, January 24). The oxygen level in air directs airway epithelial cell differentiation by controlling mitochondrial citrate export. Science Advances.

Professor Michael Welsh’s work has revolutionized the understanding and treatment of cystic fibrosis by uncovering the molecular mechanisms of CFTR dysfunction, leading to life-changing therapies for patients worldwide. His groundbreaking research bridges molecular biology and clinical medicine, driving global innovation in genetic disease treatment and advancing precision healthcare.

Prof. Tian-yun Wang | Genetics and Molecular Biology | Scientific Excellence Achievement Award

Published on by Shen Awards

Prof. Tian-yun Wang | Genetics and Molecular Biology | Scientific Excellence Achievement Award

Henan Medical University, China

Prof. Tianyun Wang is a renowned Professor in the Department of Biochemistry and Molecular Biology at Xinxiang Medical University, China, recognized for his pioneering contributions to molecular genetics and recombinant protein engineering. He holds a Ph.D. in Genetics from Zhengzhou University (2005), a Master’s degree in Biochemical Engineering from Shanghai University (2001), and a Bachelor’s degree in Biological Education from Qufu Normal University (1993). With over two decades of academic and research excellence, Prof. Wang has served as Professor and Deputy Director at Xinxiang Medical University since 2012, following earlier roles as Associate Professor and Lecturer. His professional expertise lies in cellular bioengineering, molecular genetics, and protein expression, particularly in advancing recombinant protein production in Chinese Hamster Ovary (CHO) cells—a cornerstone in modern biopharmaceutical development. Prof. Wang’s research interests include genetic regulation, molecular cloning, and the biotechnological enhancement of therapeutic protein yield and quality. His technical proficiency encompasses advanced cell culture systems, gene editing, molecular modeling, and bioinformatics analysis, reflecting a strong command of both experimental and computational tools. With 170 publications, 2,513 citations, and an h-index of 24, his scholarly output underscores his global influence and sustained scientific innovation. His honors include the Scientific Innovation Talent Award (2015), Outstanding Teacher Award (2012), and multiple provincial science and technology prizes, reflecting his excellence in both research and education. Prof. Wang has successfully led numerous nationally funded research projects, contributing significantly to China’s biotechnological advancement. His academic leadership, research acumen, and mentorship have shaped many young scientists in molecular life sciences. In conclusion, Prof. Tianyun Wang stands as a distinguished scholar whose visionary research and commitment to innovation continue to bridge molecular biology and industrial biotechnology, driving forward advancements in recombinant protein production and contributing meaningfully to global biomedical science.

Profiles: Scopus | ORCID

Featured Publications

  1. Han, Z., Han, X., Cheng, W., Geng, S., Li, W., Wang, T., & Wang, X. (2025). Application of transposon expression system in recombinant protein expression and gene therapy. Biochimie.

  2. Geng, S., Zou, Y., Bai, Z., Zhang, M., Wang, C., & Wang, T. (2025). Serum‐free medium for recombinant protein expression in insect cells. Biotechnology and Applied Biochemistry.

  3. Yuan, J., Geng, S., & Wang, T. (2025). Research progress fusion tags for recombinant protein production. Biotechnology and Applied Biochemistry.

  4. Wang, C., Guo, X., Wang, W., Li, J. X., & Wang, T. (2025). From cell clones to recombinant protein product heterogeneity in Chinese hamster ovary cell systems. International Journal of Molecular Sciences, 26(3), 1324.

  5. Fu, Y., Han, Z., Cheng, W., Niu, S., Wang, T., & Wang, X. (2024). Improvement strategies for transient gene expression in mammalian cells. Applied Microbiology and Biotechnology.

Prof. Tianyun Wang’s work significantly advances global biopharmaceutical innovation through cutting-edge research in recombinant protein engineering and molecular genetics. His contributions enhance the efficiency of therapeutic protein production, bridging scientific discovery with industrial biotechnology to improve healthcare and promote sustainable biomedical development worldwide.