Dr. Ghasem Solgi is a seasoned medical immunologist with extensive experience in both academic and clinical research settings. Born in 1976 in Iran, he has dedicated over two decades to advancing the field of immunology, particularly in transplantation and immunogenetics. As the Head of the Immunogenetics Lab at Hamadan University of Medical Sciences, Dr. Solgi has played a pivotal role in shaping research in HLA-related immunology and autoimmune diseases. His research primarily investigates the role of HLA genes in disease susceptibility, treatment response, and transplant outcomes, contributing valuable insights to clinical immunology. Dr. Solgi’s leadership experience, including his tenure as Deputy for Research Affairs and Head of the Immunology Department, reflects his commitment to both scientific inquiry and academic governance. He has mentored numerous graduate and postgraduate students, actively participates in peer review for high-impact journals, and maintains membership in respected scientific societies. His multidisciplinary approach, which bridges immunogenetics, autoimmune diseases, and clinical transplant immunology, underscores the translational impact of his work. With an impressive history of scientific supervision and collaboration, Dr. Solgi continues to contribute to the global immunology community through both innovative research and the nurturing of future scholars.

Professional Profile

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Education

Dr. Ghasem Solgi holds a strong academic foundation in medical immunology, shaped by rigorous training at renowned institutions. He earned his Ph.D. in Medical Immunology from Tehran University of Medical Sciences in 2009. His doctoral thesis focused on the effects of donor bone marrow cell infusion on microchimerism and allograft outcomes in kidney transplant patients, followed by a comprehensive five-year follow-up study—highlighting his early dedication to transplantation immunology. Prior to his doctoral studies, Dr. Solgi completed his M.Sc. in Medical Immunology at Isfahan University of Medical Sciences in 2002. His master’s thesis compared serological and DNA-based methods for HLA typing in kidney allograft recipients, laying the groundwork for his long-standing focus on HLA research. Further enriching his expertise, he undertook a practical course and thesis completion in Transplantation Immunology at IKT in Ulm, Germany, during 2008–2009. This international experience not only refined his technical skills but also exposed him to diverse scientific environments. Dr. Solgi’s educational trajectory demonstrates a consistent commitment to excellence in immunology, emphasizing both theoretical knowledge and hands-on laboratory experience. His academic preparation has been instrumental in shaping his career as a researcher, educator, and clinical immunology expert.

Professional Experience

Dr. Ghasem Solgi has accumulated a wealth of professional experience in academia and research since earning his doctoral degree. He currently serves as the Head of the Immunogenetics Lab in the Immunology Department at Hamadan University of Medical Sciences, a role he has held since 2020. From 2016 to 2020, he was the Deputy for Research Affairs of the Medical School, where he contributed to strategic planning and research development. Previously, between 2015 and 2019, he served as the Head of the Immunology Department at the same institution, reflecting his leadership capabilities and influence on departmental growth. Earlier in his career, Dr. Solgi worked as an Assistant Professor in the Immunology Department at Hamadan University (2012–2015) and Ahvaz Jundishapur University of Medical Sciences (2009–2012). These academic roles have allowed him to balance research, teaching, and mentorship, while advancing the university’s immunology programs. His career path demonstrates a steady progression of leadership in both scientific and administrative capacities. Through his sustained involvement in immunogenetics and autoimmune research, Dr. Solgi has cultivated a distinguished profile, earning respect from colleagues, students, and collaborators alike.

Research Interests

Dr. Ghasem Solgi’s research interests lie primarily in the field of immunogenetics and transplantation immunology, with a particular focus on the Human Leukocyte Antigen (HLA) system and its relationship to disease pathogenesis and therapeutic outcomes. His studies aim to understand how genetic and immunological factors influence immune responses in organ transplantation and autoimmune disorders. Specifically, he investigates the distribution of HLA alleles and haplotypes in diseases such as type 1 diabetes (T1D), multiple sclerosis (MS), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and their correlation with susceptibility, disease severity, and treatment response. Dr. Solgi has also examined the role of HLA in COVID-19, exploring genetic predisposition to disease severity. His transplantation research includes microchimerism analysis, anti-HLA antibody detection, and long-term survival of kidney transplant patients. These interdisciplinary topics combine clinical relevance with molecular insights, aiming to improve diagnosis, prognosis, and personalized treatment strategies. His dedication to integrating immunogenetic data with clinical outcomes has placed his research at the intersection of translational medicine and precision immunology. This comprehensive scope not only addresses pressing healthcare challenges but also contributes to evolving strategies in immunotherapy and transplant compatibility assessment.

Research Skills

Dr. Ghasem Solgi possesses a robust set of research skills that span molecular biology, immunogenetics, and clinical immunology. He has extensive expertise in HLA typing using both serological and DNA-based methods, which he applied early in his career and further developed through practical training in Germany. His technical proficiency includes flow cytometry, ELISA, PCR-based genotyping, and microchimerism analysis—essential tools for studying immune responses in transplant recipients and autoimmune patients. Dr. Solgi is skilled in study design, biostatistical analysis, and survival analysis, which are critical in assessing long-term patient outcomes in kidney transplantation. He is also experienced in conducting family-based genetic studies to evaluate allelic distribution in disease populations. His ability to integrate laboratory findings with clinical parameters demonstrates a high level of translational research competency. In addition, Dr. Solgi’s editorial contributions to numerous international journals reflect his critical appraisal skills and deep understanding of current scientific methodologies. His mentoring record further showcases his ability to transfer knowledge and guide complex research projects, making him not only a proficient investigator but also a collaborative academic leader in immunology and genetic research.

Awards and Honors

While specific awards are not explicitly listed in the available documentation, Dr. Ghasem Solgi’s professional trajectory and academic appointments reflect significant recognition and respect within the scientific community. His leadership roles—such as Head of the Immunogenetics Lab, Head of the Immunology Department, and Deputy for Research Affairs—demonstrate institutional trust and acknowledgment of his scientific contributions. Additionally, his long-standing memberships in prominent organizations such as the Iranian Society of Immunology and Allergy (since 2006) and the European Federation for Immunogenetics (since 2010) further signify professional standing. Dr. Solgi’s participation as a manuscript reviewer for more than a dozen respected journals, including Scientific Reports, Journal of Clinical Medicine, Human Immunology, and Diagnostics, underscores his expertise and influence in shaping contemporary immunological research. These editorial responsibilities are a form of professional recognition typically granted to well-established researchers. His record of supervising graduate and postgraduate students also reflects academic confidence in his mentorship and leadership. While formal awards could be added to enhance visibility, Dr. Solgi’s contributions, impact, and peer acknowledgment position him as a highly respected figure in his field.

Conclusion

Dr. Ghasem Solgi is a highly accomplished immunologist whose work bridges fundamental research and clinical application, particularly in the areas of transplantation immunology and immunogenetics. With an educational background grounded in top-tier Iranian institutions and complemented by international training, he has consistently demonstrated academic rigor and scientific curiosity. His professional roles across two leading Iranian universities, combined with his leadership of research labs and departments, reveal a strong commitment to advancing medical science and nurturing future experts. Dr. Solgi’s research has yielded valuable insights into the HLA system’s role in autoimmune diseases and transplant outcomes, contributing to the development of more effective diagnostic and therapeutic strategies. He possesses strong technical and analytical research skills, and his involvement in numerous peer-reviewed journals speaks to his academic credibility. Although additional international awards or collaborations would further elevate his profile, the depth and impact of his work firmly establish him as a deserving nominee for the Best Researcher Award. Dr. Solgi’s enduring contributions to immunology, combined with his leadership and mentorship, make him a vital asset to both the academic community and the broader field of clinical research.

Publications Top Notes

1. Chemical Contamination in the Extracted DNA Affects the Results of HLA Typing by the PCR-SSOP Method

• Authors: A. Shirizadeh, M. Ebrahimpur, S. Soltani, G. Solgi

• Journal: Molecular Biology Reports

• Year: 2025

• Citations: 2

2. A Potential Link Between HLA-DRB1/DQB1 Alleles and Response to Treatment in Rheumatoid Arthritis Patients

• Authors: A. Tahamoli-Roudsari, A. Rasouli-Saravani, Z. Basiri, M. Hajilooei, G. Solgi

• Journal: International Journal of Immunogenetics

• Year: 2025

3. Potential Contribution of Gut Microbiota in the Development of Autoantibodies in T1D Children Carrying HLA-DRB1/DQB1 Risk Alleles: An Experimental and In Silico Analysis

• Authors: A. Shirizadeh, Z. Razavi, V. Saeedi, J. Faradmal, G. Solgi

• Journal: Immunogenetics

• Year: 2024

• Citations: 1

4. MicroRNA -21 Expression as an Auxiliary Diagnostic Biomarker of Acute Brucellosis

• Authors: M. Rezaeepoor, F. Keramat, S. Jourghasemi, M. Hajilooei, G. Solgi

• Journal: Molecular Biology Reports

• Year: 2024

5. Peripheral Blood Mononuclear Cells Show Markers of Mitochondrial Dysfunction in Rheumatoid Arthritis

• Authors: A. Abbasifard, G. Solgi, I. Khodadadi, H. Tayebinia, A. Fazaeli

• Journal: Cell Biochemistry and Function

• Year: 2024

• Citations: 1

6. Determination of HLA Class II Risk Alleles and Prediction of Self/Non-Self-Epitopes Contributing Hashimoto’s Thyroiditis in a Group of Iranian Patients

• Authors: A. Shirizadeh, S. Borzouei, Z. Razavi, J. Faradmal, G. Solgi

• Journal: Immunogenetics

• Year: 2024

7. Family-Based Association of HLA-DRB1 and DQB1 Alleles and Haplotypes in a Group of Iranian Type 1 Diabetes Children

• Authors: A. Shirizadeh, Z. Razavi, V. Saeedi, G.E. Morahan, G. Solgi

• Journal: HLA

• Year: 2024

• Citations: 3

8. Epigenetic Regulation of FOXP3 Gene Expression in Relation to Impaired Function of Regulatory T Cells in Systemic Lupus Erythematosus

• Authors: P. Fakour, A. Shirizadeh, A. Tahamoli-Roudsari, G. Solgi

• Journal: Not specified

• Citations: 1