Researcher/Professor from INQUISUR-CONICET/UNS, Argentina
Dr. Luciano Alejandro Benedini is an accomplished Argentine researcher specializing in pharmaceutical nanotechnology, biomaterials, and drug delivery systems. Serving as an Adjunct Researcher at INQUISUR-CONICET and Assistant Professor at the Universidad Nacional del Sur (UNS) since 2001, he has significantly contributed to the field of pharmaceutical sciences. Dr. Benedini’s work focuses on the development of nanostructured systems for drug delivery, bone tissue engineering, and the study of colloidal properties of pharmaceutical compounds. His extensive publication record includes over 20 peer-reviewed journal articles and multiple book chapters, reflecting his active engagement in cutting-edge research. Additionally, he has been recognized with several prestigious awards, such as the “INNOVAR 2023” distinction and the Aaron and Fanny Fidelef de Nijamkim’s Award for Best PhD in Chemistry. His dedication to research excellence and innovation makes him a strong candidate for the Best Researcher Award.
Professional Profile
Education
Dr. Benedini’s academic journey began with a degree in Pharmacy from the Universidad Nacional del Sur (UNS), completed between 1997 and 2003. He further pursued his passion for research by obtaining a Ph.D. in Chemistry from the same institution, with his doctoral studies spanning from 2008 to 2012. His thesis, titled “Interaction between a biocompatible surfactant with pharmacological interest structures,” delved into the interactions of biocompatible surfactants with pharmacologically relevant structures, laying the groundwork for his future research endeavors in drug delivery systems and nanotechnology. This robust educational foundation has equipped him with the necessary skills and knowledge to excel in the interdisciplinary field of pharmaceutical sciences.
Professional Experience
Dr. Benedini has amassed over two decades of professional experience in both academic and research settings. Since 2001, he has served as an Assistant Professor in the Department of Biology, Biochemistry, and Pharmacy at UNS, where he has been instrumental in teaching and mentoring students. Concurrently, he holds the position of Adjunct Researcher at INQUISUR-CONICET, a role he has fulfilled since 2015. His professional journey also includes valuable international exposure through postdoctoral fellowships at the University of Santiago de Compostela in Spain and Bielefeld University in Germany. These experiences have enriched his research perspective and facilitated collaborations with leading scientists in his field. Additionally, Dr. Benedini has contributed to the public health sector by practicing as a pharmacist from 2003 to 2008, further demonstrating his commitment to applying scientific knowledge for societal benefit.
Research Interests
Dr. Benedini’s research interests are centered around the development of innovative drug delivery systems, with a particular focus on nanotechnology and biomaterials. He explores the design and characterization of nanostructured carriers, such as liposomes and hydroxyapatite-based composites, for targeted and controlled drug release. His work aims to enhance the efficacy and safety of therapeutic agents, especially in the context of bone tissue engineering and regenerative medicine. Additionally, he investigates the physicochemical properties of pharmaceutical compounds and their interactions with biological membranes, contributing to a deeper understanding of drug behavior at the molecular level. Dr. Benedini’s interdisciplinary approach bridges chemistry, biology, and materials science, positioning him at the forefront of pharmaceutical research.
Research Skills
Dr. Benedini possesses a comprehensive skill set that encompasses various aspects of pharmaceutical research. His expertise includes the synthesis and characterization of nanomaterials, formulation of drug delivery systems, and evaluation of their biological performance. He is proficient in techniques such as spectroscopy, electron microscopy, and rheological analysis, which are essential for assessing the structural and functional properties of biomaterials. Furthermore, his experience in conducting in vitro and in vivo studies enables him to translate laboratory findings into potential clinical applications. Dr. Benedini’s collaborative work with international research groups and his role as a reviewer for esteemed scientific journals underscore his analytical acumen and commitment to maintaining high research standards.
Awards and Honors
Dr. Benedini’s contributions to science have been recognized through numerous awards and honors. Notably, he received the “INNOVAR 2023” distinction from the Ministry of Science and Innovation in the Applied Research category for his project on NanoA. His doctoral research earned him the Aaron and Fanny Fidelef de Nijamkim’s Award for Best PhD in Chemistry in 2012. He has been granted several prestigious fellowships, including postdoctoral positions funded by Fundación Carolina and CONICET, facilitating his research endeavors in Spain and Germany. Additionally, his commitment to societal impact is evident from the First Prize awarded at the 2nd Ibero-American Virtual Congress on Environmental Health in 2024 for his work on raising awareness about drug pollution among school-aged children. These accolades reflect Dr. Benedini’s dedication to advancing scientific knowledge and addressing real-world challenges.
Conclusion
Dr. Luciano Benedini exemplifies the qualities of an outstanding researcher through his extensive academic background, innovative research contributions, and commitment to societal impact. His interdisciplinary approach, combining chemistry, biology, and materials science, has led to significant advancements in drug delivery systems and biomaterials. The recognition he has received from both national and international institutions attests to the relevance and quality of his work. Dr. Benedini’s dedication to mentoring, collaboration, and addressing pressing health issues positions him as a leading figure in pharmaceutical research. His achievements make him a deserving candidate for the Best Researcher Award, reflecting his unwavering commitment to scientific excellence and innovation.
Publications Top Notes
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Antibacterial alginate/nano-hydroxyapatite composites for bone tissue engineering: Assessment of their bioactivity, biocompatibility, and antibacterial activity
L. Benedini, J. Laiuppa, G. Santillán, M. Baldini, P. Messina
Materials Science and Engineering: C, 115, 111101 (2020) — 82 citations
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Adsorption/desorption study of antibiotic and anti-inflammatory drugs onto bioactive hydroxyapatite nano-rods
L. Benedini, D. Placente, J. Ruso, P. Messina
Materials Science and Engineering: C, 99, 180–190 (2019) — 56 citations
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The ascorbyl palmitate-water system: Phase diagram and state of water
L. Benedini, E.P. Schulz, P.V. Messina, S.D. Palma, D.A. Allemandi, P.C. Schulz
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 375 (1–3) (2011) — 50 citations
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Multi-drug delivery system based on lipid membrane mimetic coated nano-hydroxyapatite formulations
D. Placente, L.A. Benedini, M. Baldini, J.A. Laiuppa, G.E. Santillán, …
International Journal of Pharmaceutics, 548 (1), 559–570 (2018) — 42 citations
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Biomimetic fiber mesh scaffolds based on gelatin and hydroxyapatite nano-rods: Designing intrinsic skills to attain bone reparation abilities
J. Sartuqui, A.N. Gravina, R. Rial, L.A. Benedini, L.H. Yahia, J.M. Ruso, …
Colloids and Surfaces B: Biointerfaces, 145, 382–391 (2016) — 39 citations
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Self-assembly of 33-mer gliadin peptide oligomers
M.G. Herrera, L.A. Benedini, C. Lonez, P.L. Schilardi, T. Hellweg, …
Soft Matter, 11 (44), 8648–8660 (2015) — 36 citations
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Colloidal properties of amiodarone in water at low concentration
L. Benedini, P.V. Messina, R.H. Manzo, D.A. Allemandi, S.D. Palma, E.P. Schulz, …
Journal of Colloid and Interface Science, 342 (2), 407–414 (2010) — 35 citations
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Ascorbyl palmitate interaction with phospholipid monolayers: electrostatic and rheological preponderancy
M. Mottola, N. Wilke, L. Benedini, R.G. Oliveira, M.L. Fanani
Biochimica et Biophysica Acta (BBA) – Biomembranes, 1828 (11), 2496–2505 (2013) — 33 citations
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Biopolymers for medical applications
J.M. Ruso, P.V. Messina
CRC Press (2017) — 31 citations
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Surface phase behavior and domain topography of ascorbyl palmitate monolayers
L. Benedini, M.L. Fanani, B. Maggio, N. Wilke, P. Messina, S. Palma, P. Schulz
Langmuir, 27 (17), 10914–10919 (2011) — 31 citations
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Assessment of synergistic interactions on self-assembled sodium alginate/nano-hydroxyapatite composites: to the conception of new bone tissue dressings
L. Benedini, D. Placente, O. Pieroni, P. Messina
Colloid and Polymer Science, 295, 2109–2121 (2017) — 19 citations
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Study of the influence of ascorbyl palmitate and amiodarone in the stability of unilamellar liposomes
L. Benedini, S. Antollini, M.L. Fanani, S. Palma, P. Messina, P. Schulz
Molecular Membrane Biology, 31 (2–3), 85–94 (2014) — 19 citations
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Development of a nonionic azobenzene amphiphile for remote photocontrol of a model biomembrane
L.A. Benedini, M.A. Sequeira, M.L. Fanani, B. Maggio, V.I. Dodero
The Journal of Physical Chemistry B, 120 (17), 4053–4063 (2016) — 14 citations
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Understanding Recognition and Self-assembly in Biology using the Chemist’s Toolbox. Insight into Medicinal Chemistry
Z.B. Quirolo, L.A. Benedini, M.A. Sequeira, M.G. Herrera, T.V. Veuthey, …
Current Topics in Medicinal Chemistry, 14 (6), 730–739 (2014) — 11 citations
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Phase behavior of ascorbyl palmitate coagels loaded with oligonucleotides as a new carrier for vaccine adjuvants
G.V. Ullio Gamboa, L.A. Benedini, P.C. Schulz, D.A. Allemandi
Journal of Surfactants and Detergents, 19, 747–757 (2016) — 10 citations