Mr. Jan Hendrik Muller | Oncology and Pathology | Best Researcher Award
University Clinic Hamburg Eppendorf | Germany
Mr. Jan Hendrik Müller is an accomplished researcher in molecular life sciences with a specialization in cancer proteomics and translational medicine. Currently pursuing his Ph.D. at the Institute of Pathology, University Medical Center Hamburg-Eppendorf, he has established himself as a promising scientist with expertise in cutting-edge proteomic technologies such as LC-MS/MS and mass spectrometry. His academic career reflects a strong foundation in molecular biology, proteomics, and life science research, supported by rigorous training at leading German institutions including the University of Hamburg and Leibniz University Hannover. Jan’s research focuses on understanding cancer biology at the proteomic level, with the aim of identifying novel biomarkers and therapeutic targets. Alongside his academic journey, he has contributed as a research assistant in internationally recognized groups, gaining practical experience in experimental oncology, T-cell research, and collaborative scientific projects. His involvement in both laboratory research and medical volunteer work highlights his dedication to bridging science and societal benefit. Beyond technical expertise, Jan brings leadership, adaptability, and teamwork to his professional profile, making him a well-rounded candidate for recognition. His ability to integrate scientific curiosity with practical applications positions him as a researcher with significant potential to impact both academia and medical science in the future.
Professional Profile
Education
Mr. Jan Hendrik Müller has pursued a progressive and rigorous academic journey in the field of life sciences, developing expertise in molecular biology, proteomics, and translational medicine. He began his higher education at Leibniz University Hannover, where he earned his Bachelor of Science (B.Sc.) in Life Science. During his undergraduate years, Jan developed proficiency in molecular biology techniques including PCR, protein isolation, and confocal microscopy. His bachelor’s thesis, titled “The effects of dextran sodium sulfate on the barrier function of epithelial cells,” allowed him to gain experience in cell culture and epithelial biology. Following this, Jan pursued his Master of Science (M.Sc.) in Molecular Life Science at the University of Hamburg, completing his degree with excellent academic standing. His master’s studies were research-oriented, involving advanced training in proteomics under the guidance of Prof. Dr. Hartmut Schlüter. His projects included mass spectrometry analysis of prostate cancer tissue, contributing to translational cancer research. Building upon this foundation, Jan is currently enrolled in a Doctor of Philosophy (Ph.D.) program at the University Medical Center Hamburg-Eppendorf, focusing on cancer proteomics and drug response profiling. His educational background demonstrates consistent excellence, hands-on laboratory expertise, and a strong commitment to advancing biomedical research.
Professional Experience
Mr. Jan Hendrik Müller’s professional experience demonstrates a balanced combination of academic research, laboratory training, and clinical exposure. Early in his career, he trained as a paramedic and served in hospital settings, gaining valuable insights into patient care and surgical assistance, particularly in orthopedic surgeries. These experiences nurtured his sense of responsibility and motivated his transition from clinical service to biomedical research. During his academic career, he worked as a Research Assistant in the laboratory of Prof. Dr. Hartmut Schlüter at the University Medical Center Hamburg-Eppendorf. There, he specialized in proteomic analysis of prostate cancer tissue using LC-MS/MS, gaining expertise in mass spectrometry, sample preparation, and proteomic pathway analysis. He also contributed to collaborative projects on T-cell immunotherapy, including viral transduction and functional assays for CAR-T-cell research. In addition, Jan has managed laboratory responsibilities such as cryobank administration and patient sample handling, demonstrating both technical and organizational skills. His professional development is also marked by active teamwork in multidisciplinary projects and community service in hospital environments. These diverse experiences highlight his ability to integrate clinical relevance with scientific discovery, making him a well-rounded researcher equipped for impactful contributions to cancer biology and translational medicine.
Research Interests
Mr. Jan Hendrik Müller’s research interests lie at the intersection of molecular biology, proteomics, and translational oncology. His primary focus is the proteomic profiling of cancer tissues, particularly prostate cancer, using advanced techniques such as liquid chromatography coupled with mass spectrometry (LC-MS/MS). Through this approach, he seeks to unravel the molecular mechanisms underlying cancer progression and drug responses, with the goal of identifying novel therapeutic targets and biomarkers for early diagnosis. In addition to cancer proteomics, Jan is also interested in immunotherapy research, having gained experience in CAR-T-cell biology, viral transduction methods, and T-cell functional assays. His broader research goals include integrating proteomic data with systems biology to provide holistic insights into cellular pathways affected by novel drug treatments. Beyond oncology, Jan shows interest in the applications of molecular life sciences in personalized medicine, aiming to develop strategies that bridge fundamental research with clinical application. His interdisciplinary approach reflects his commitment to collaborative science, combining expertise in molecular biology, analytical chemistry, and clinical medicine. Ultimately, his research interests highlight a forward-looking vision to contribute meaningfully to cancer research, drug development, and precision medicine.
Research Skills
Over the course of his academic and professional journey, Mr. Jan Hendrik Müller has developed a broad and advanced skill set in experimental life sciences and proteomics. His expertise includes molecular biology techniques such as PCR, protein production, blotting, and electrophoresis, alongside advanced cell culture methods, including the maintenance of various cell lines and epithelial barrier function analysis. He is proficient in high-level proteomic methodologies, particularly LC-MS/MS and mass spectrometry-based proteome analysis, enabling him to study complex biological samples with precision. In the field of immunology, he has acquired skills in isolation, expansion, and viral transduction of T-cells, as well as functional CAR-T-cell assays. Jan also has experience in fluorescence-activated cell sorting (FACS), confocal microscopy, and proteomic pathway analysis, demonstrating technical versatility. Beyond laboratory skills, he is proficient in bioinformatics tools such as ImageJ, Matlab, and LaTeX for data visualization and documentation. His certifications include Good Manufacturing Practices (GMP), further enhancing his competency in clinical-grade research. In addition, Jan has proven skills in teamwork, problem-solving, and communication, strengthened by his volunteer work in medical and community settings. Together, his research skills position him as a highly capable scientist ready to contribute to complex biomedical projects.
Awards and Honors
While still in the early stages of his academic career, Mr. Jan Hendrik Müller has already received recognition for his academic and professional excellence. During his Master of Science program at the University of Hamburg, he achieved excellent grades, including a distinction in several advanced courses. His bachelor’s and master’s theses received commendation for their originality and scientific rigor, particularly in the field of proteomics and epithelial biology. Jan has also been awarded a certificate in Good Manufacturing Practices (GMP), reflecting his adherence to the highest standards of laboratory and clinical research practices. In addition to formal recognition, his contribution to research projects under internationally respected mentors such as Prof. Dr. Hartmut Schlüter has allowed him to build a reputation as a promising scientist in proteomics research. His community service in hospital environments and volunteer platforms further demonstrate his commitment to societal well-being. While he has yet to receive large-scale international honors, his strong research foundation, combined with his growing publication record and academic contributions, suggests a career trajectory that will lead to greater recognition in the global scientific community in the near future.
Publication TOp Notes
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High-level STING expression in tumour and inflammatory cells is linked to microsatellite instability and favourable tumour parameters in a cohort of over 1,900 colorectal cancer patients — 2025
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A Tc1- and Th1-T-lymphocyte-rich tumor microenvironment is a hallmark of MSI colorectal cancer — 2025
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Prognostic Impact and Spatial Interplay of Immune Cells in Urothelial Cancer — 2024
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Loss of TROP2 and epithelial cell adhesion molecule expression is linked to grade progression in pTa but unrelated to disease outcome in pT2-4 urothelial bladder carcinomas — 2024
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Automated Prognosis Marker Assessment in Breast Cancers Using BLEACH&STAIN Multiplexed Immunohistochemistry — 2023
Conclusion
In conclusion, Mr. Jan Hendrik Müller exemplifies the qualities of a dedicated and innovative young researcher in the field of molecular life sciences and cancer proteomics. His academic excellence, demonstrated through his bachelor’s, master’s, and ongoing Ph.D. studies, reflects his consistent pursuit of scientific knowledge and translational medicine. His professional experiences, ranging from hospital assistance to advanced cancer proteomic research, reveal a well-rounded individual capable of integrating clinical insights with laboratory discoveries. With expertise in proteomics, immunotherapy, and molecular biology, Jan has built a diverse skill set that positions him as a valuable contributor to biomedical science. His community involvement, volunteer medical service, and collaborative research engagements highlight his leadership qualities and social responsibility. While there is room for further recognition through expanded publications and global collaborations, his trajectory demonstrates great promise. Jan is not only contributing to cancer research but is also laying the foundation for impactful work in personalized medicine and future healthcare innovation. These achievements, combined with his dedication, make him a deserving candidate for recognition and a strong contender for future leadership in biomedical research.