Valentina Giai | Ematologia | Women Researcher Award

Dr. Valentina Giai | Ematologia | Women Researcher Award

Città della Salute e della Scienza, Torino, Italy

Dr. Valentina Giai is a distinguished hematologist and researcher with over two decades of experience in academic medicine and clinical hematology. She completed her MD and hematology training at the University of Torino, Italy, where she later earned her PhD in Experimental Medicine. Her postdoctoral work includes significant contributions at the Karolinska Institutet in Sweden, focusing on regenerative medicine and hematopoietic stem cells. Dr. Giai has held key clinical positions across major Italian hospitals, currently serving at Città della Salute e della Scienza in Torino. Her research spans chronic myeloid leukemia, myelodysplastic syndromes, and acute myeloid leukemia, contributing to pivotal clinical trials and real-world studies. A prolific author, she has co-authored numerous high-impact publications and participated in international collaborations. Her career reflects a seamless blend of patient care, clinical innovation, and research excellence, with a commitment to improving hematologic therapies and outcomes.

Professional Profile

Scopus

Orcid

🎓 Education 

Dr. Giai’s academic foundation began at the Liceo Scientifico Marie Curie in Pinerolo (1994–1999), followed by medical studies at the University of Torino, Italy, where she graduated with top honors (110/110) in 2005. She completed a residency in Hematology (2006–2010) and earned a license as a hematology specialist in 2010. Her academic pursuits continued with a PhD in Experimental Medicine and Therapy at the University of Torino (2011–2014), supported by a grant from the Fondazione Bossolasco. Parallelly, she expanded her research capabilities through a PhD program at Karolinska Institutet, Sweden, in the Laboratory of Hematology and Regenerative Medicine. These academic experiences have equipped Dr. Giai with a robust understanding of both clinical and experimental hematology, allowing her to bridge the gap between basic science and patient-centered care. Her training reflects an international approach to hematologic research with strong foundations in molecular biology, clinical trials, and translational medicine.

💼 Professional Experience 

Dr. Valentina Giai began her clinical journey with an internship in internal medicine and hematology at the University of Torino in 2005. From 2006 to 2010, she completed her residency and fellowship in hematology at the same institution, becoming a board-certified hematologist in 2010. Her international exposure includes guest research at Karolinska Institutet in Sweden (2010–2012), where she engaged in cutting-edge hematologic research. Between 2012 and 2015, she served at the Molinette Hospital in Torino. From 2015 to 2016, she worked as a hematology consultant in Asti, followed by a tenure as attending physician in Alessandria (2015–2019). Since 2019, she has been a leading hematologist at Città della Salute e della Scienza, Torino. Across these roles, she has led clinical research, mentored junior clinicians, and collaborated on major clinical trials. Her trajectory reflects deep integration of clinical care, patient outcomes, and translational research.

🏆 Awards and Honors

Dr. Giai has been recognized for her academic and clinical excellence throughout her career. She was awarded a prestigious research grant by the Fondazione Bossolasco to pursue her PhD studies, affirming the scientific value and societal relevance of her research. Her collaborative role in the international hematology community, particularly through the Karolinska Institutet, underscores her global reputation. Many of the clinical trials she contributed to—such as QUAZAR AML-001 and studies on luspatercept and CC-486—are landmark publications in hematology and featured in journals like NEJM, JCO, and Blood. Her involvement in nationwide research networks like GIMEMA and FISiM showcases peer recognition and trust in her scientific judgment. Additionally, her contributions during the COVID-19 pandemic in the hematology context were instrumental in shaping clinical guidance in Italy. Dr. Giai’s achievements demonstrate her dedication to evidence-based medicine and advancing hematologic care.

🔬 Research Interests 

Dr. Giai’s research interests center on hematologic malignancies and disorders, particularly acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), and chronic myeloid leukemia (CML). She is deeply involved in evaluating new therapeutic strategies, including targeted agents like FLT3 inhibitors and hypomethylating agents. Her work also explores the molecular biology of hematopoiesis, leukemia stem cells, and drug resistance mechanisms. She has contributed to clinical trials assessing novel compounds such as crovalimab, luspatercept, CC-486, and gilteritinib, integrating clinical outcomes with translational biomarkers. Additionally, she has explored patient-reported outcomes and quality-of-life monitoring in CML, emphasizing the humanistic dimension of care. Dr. Giai is also active in immunological studies related to SARS-CoV-2 impacts on hematologic patients. Her interdisciplinary approach aims to improve long-term outcomes by tailoring treatment strategies based on disease biology, patient fitness, and real-world efficacy data.

🧪 Research Skills

Dr. Giai brings a versatile skill set spanning clinical trials, translational research, molecular diagnostics, and biostatistics. She is adept in designing and executing multicenter clinical trials, evidenced by her involvement in pivotal Phase II and III studies. Her lab-based experience includes work with hematopoietic stem cells, oxidative stress assays, and cellular characterization using flow cytometry and molecular markers. She has collaborated on biomarker identification, particularly in MDS and AML, and has validated prognostic scoring systems and response criteria. In addition to her technical prowess, she has contributed to data management, protocol writing, and regulatory submissions for ethical approval. Her international collaboration with Karolinska Institutet reflects her ability to conduct integrative research across institutions. Moreover, her skills extend to epidemiological surveys, quality-of-life studies, and SCORE models for cardiovascular risk in hematologic settings. She combines scientific rigor with a strong patient-centered research ethos.

Conclusion

Dr. Valentina Giai is a prominent clinical researcher and hematologist whose contributions span from translational benchwork to advanced clinical trials. With a strong academic foundation and consistent clinical involvement, she continues to shape the future of hematologic therapies. Her research legacy is deeply embedded in precision medicine, collaborative networks, and patient-focused innovation.

📚 Publication Top Notes

  1. Scheinberg P, … Giai V, 2024 – Crovalimab vs eculizumab in PNH (Am J Hematol)

  2. Urbino I, … Giai V, 2024 – Sorafenib for FLT3-ITD AML (Leuk Res)

  3. Mulas O, … Giai V, 2024 – SCORE2 cardiovascular risk in CML (Ann Hematol)

  4. Efficace F, … Giai V, 2024 – Symptom monitoring in CML (Cancer)

  5. Lanino L, … Giai V, 2023 – Luspatercept real-world study in MDS (Am J Hematol)

  6. Oliva EN, … Giai V, 2023 – Eltrombopag in low-risk MDS: Phase II trial (JCO)

  7. Apolito V, … Giai V, 2023 – AML mortality prediction with SIE/SIES/GITMO (Br J Haematol)

  8. Pacelli P, … Giai V, 2023 – CD26+ LSCs post-TKI discontinuation (Front Pharmacol)

  9. Garcia-Manero G, … Giai V, 2021 – CC-486 in lower-risk MDS (JCO)

  10. Wei AH, … Giai V, 2020 – Oral azacitidine for AML in remission (NEJM)

  11. Mossuto S, … Giai V, 2020 – COVID-19 in MDS: Italian experience (HemaSphere)

  12. Fenaux P, … Giai V, 2020 – Luspatercept for MDS (NEJM)

  13. Giannotta JA, … Giai V, 2022 – COVID-19 vaccination in PNH (Am J Hematol)

  14. Calabretto G, … Giai V, 2022 – Hypocellular MDS: immunologic profile (Leukemia)

  15. Giai V, … 2022 – Oxidative stress in MDS progenitors (J Biotechnol Biomed)

  16. Arrigo G, … Giai V, 2022 – Gilteritinib for breast relapse of AML (Acta Haematol)

  17. Giai V, … 2021 – Philadelphia-negative MPN overview (Medicina)

  18. Benevolo G, … Giai V, 2021 – Update on Polycythemia Vera treatments (Ther Clin Risk Manag)

  19. Frairia C, … Giai V, 2023 – SCORE and SOFA in AML (Eur J Haematol)

  20. Urbino I, … Giai V, 2023 – Levofloxacin prophylaxis in AML (Mediterr J Hematol Infect Dis)

  21. Aydin S, … Giai V, 2023 – AML fitness evaluation using HCT-CI, G8 (Cancers)

  22. Martella F, … Giai V, 2022 – Thrombosis risk in AML & MDS (Ann Hematol)

  23. Giai V, … 2016 – Imatinib discontinuation in CML (Br J Haematol)

  24. Ferrero D, … Giai V, 2009 – EPO + vitamin D in MDS anemia (Br J Haematol)

  25. Lobetti-Bodoni C, … Giai V, 2012 – Telomere loss in CML (Mech Ageing Dev)

  26. Ferrero D, … Giai V, 2014 – Maintenance chemotherapy in AML/MDS (Ann Hematol)

  27. Scharenberg C, … Giai V, 2017 – Mutations predicting del(5q) progression in MDS (Haematologica)

  28. Nikpour M, … Giai V, 2013 – ABCB7 in sideroblastic anemia (Leukemia)

Osman Amir | Hematology | Best Researcher Award

Mr. Osman Amir | Hematology | Best Researcher Award

Karary University, Sudan

Osman Amir Osman Mohammed is a Sudanese medical laboratory scientist with extensive experience in haematology, clinical diagnostics, public health research, and humanitarian medical services. Born in Khartoum, Sudan in 1990, he has consistently demonstrated a strong commitment to medical research, laboratory practices, and community health initiatives. His career spans over a decade of hands-on laboratory work, participation in national and international health surveys, and a growing body of scientific publications. Osman’s research focuses on haematological parameters, infectious diseases, epidemiology, and the impact of chronic illnesses such as diabetes and COVID-19 on patient outcomes. He is also an active peer reviewer for several reputable journals, contributing to the advancement and quality assurance of medical research. Throughout his career, Osman has collaborated with organizations such as the World Health Organization (WHO) and the Sudanese Federal Ministry of Health, indicating his role in important national health initiatives. His dedication to both clinical practice and academic research makes him a well-rounded professional in his field. Currently pursuing his PhD in Medical Laboratory Science with a specialization in Haematology, Osman continues to develop his expertise and contribute valuable insights to the scientific and medical communities.

Professional Profile

Education

Osman Amir Osman Mohammed has pursued a progressive academic path centered on medical laboratory science and haematology. He earned his Bachelor of Science degree in Medical Laboratory Science from the University of Medical Sciences and Technology, Khartoum, Sudan, between 2007 and 2011, graduating with an Excellent distinction. This foundational degree provided him with a broad knowledge base covering chemical pathology, haematology, histopathology, immunology, microbiology, molecular biology, and laboratory safety management. To enhance his qualifications, he completed a high diploma qualifying year at the Institute of Endemic Diseases at the University of Khartoum from 2012 to 2013, gaining advanced exposure to immunology, epidemiology, and molecular biology. His pursuit of specialized knowledge continued with a Master’s degree in Medical Laboratory Science, majoring in Haematology, from Al-Neelain University, completed between 2015 and 2017. Osman’s academic journey reflects a commitment to continuous learning, culminating in his current PhD studies in Medical Laboratory Science with a focus on haematology at Karary University, which he commenced in 2022. His educational background demonstrates depth, diversity, and specialization in both clinical and research aspects of medical science.

Professional Experience

Osman Amir Osman Mohammed has developed an impressive professional portfolio that spans clinical laboratory practice, public health research, and humanitarian outreach. His career began in 2010 as a coordinator for medical convoys and health day events at the University of Medical Sciences and Technology and later with the Northern Son’s Organization in Kassala State. He subsequently worked as a Laboratory Technologist at the Central Police Hospital in Kassala from 2011 to 2014. Osman’s experience expanded to national surveys, including the National Tuberculosis Survey and the EmONC Assessment Program, where he contributed as a laboratory technologist, data collector, data analyst, and report writer under the Federal Ministry of Health in collaboration with the World Health Organization. From 2015 to 2022, he served as a Lab Technologist at Path Lab Center in Khartoum and currently works at Saqadi West Rural Hospital in River Nile State. In addition, since 2017, Osman has provided independent medical data curation and analysis services, demonstrating his proficiency in research methodologies and statistical evaluation. His extensive hands-on experience in laboratory diagnostics and public health programs underscores his ability to bridge clinical practice with research excellence.

Research Interest

Osman Amir Osman Mohammed’s research interests are rooted in haematology and extend to infectious diseases, chronic disease management, and public health epidemiology. He is particularly focused on studying haematological indicators such as platelet-lymphocyte ratios and their clinical implications in post-transplant and COVID-19 patients. Osman is also interested in the prognosis of infectious diseases and has explored the impact of thrombocytopenia in COVID-19 pneumonia, as well as neurological manifestations among infected patients. His work encompasses investigations into diabetes management, insulin therapy knowledge among diabetic patients, and the detection of Helicobacter pylori using histochemical and immunohistochemical methods. Osman’s research spans hospital-based studies, multi-center retrospective analyses, and community health evaluations. He is driven by the desire to improve clinical outcomes through early diagnosis, accurate laboratory analysis, and data-driven decision-making. His research integrates both patient-centered and laboratory-focused approaches to address pressing health issues in Sudan and beyond. Osman’s ongoing PhD studies further align with his aim to contribute novel findings to the field of haematology while enhancing healthcare strategies for chronic and infectious diseases.

Research Skills

Osman Amir Osman Mohammed possesses a diverse set of research skills that support both clinical and epidemiological studies. His core competencies include proficiency in Microsoft Office applications, essential for data management and report writing, and specialized use of statistical software such as SPSS for medical research analysis. He is also skilled in using CS Pro v. 7.0 for census and survey statistics, demonstrating his capability to handle complex datasets efficiently. Osman’s laboratory expertise includes haematology diagnostics, histopathological evaluations, and quality control practices essential for reliable medical analysis. His field experience has enabled him to develop advanced skills in medical data curation, collection, and analysis, making him adept at handling multi-center studies and national surveys. Additionally, Osman’s peer review contributions to respected journals showcase his ability to critically evaluate scientific work and uphold research integrity. His collaborative engagements with national and international health programs further reflect his ability to apply research methodologies in real-world healthcare settings. His technical proficiency, combined with analytical thinking and scientific writing abilities, make him a well-rounded researcher with a comprehensive skill set.

Awards and Honors

While specific awards and honors have not been detailed in Osman Amir Osman Mohammed’s professional record, his consistent involvement in national health initiatives and collaborations with global health organizations like the World Health Organization reflect the recognition of his expertise and reliability in the medical research community. Osman’s extensive list of peer-reviewed publications demonstrates his growing reputation as a credible and impactful researcher. His selection as a peer reviewer for reputable journals such as Health Science Reports, Acta Biomedica, EC Microbiology, and the World Journal of Gastroenterology further serves as an implicit acknowledgment of his scientific competence. His contributions to COVID-19-related research and large-scale national surveys underline his significant role in critical health studies within Sudan. Participation in high-impact projects, such as the National Tuberculosis Survey and the EmONC Assessment, positions him as a respected figure among public health researchers. Although formal individual awards are not highlighted, Osman’s professional achievements, publications, and reviewer engagements signify the academic and clinical community’s recognition of his contributions to advancing medical knowledge and improving healthcare outcomes.

Conclusion

Osman Amir Osman Mohammed stands out as a dedicated, skilled, and impactful medical researcher with substantial experience in both laboratory and field-based healthcare projects. His academic achievements, practical expertise, and notable research contributions in haematology and infectious disease management demonstrate his commitment to scientific advancement and community health. Osman’s ability to integrate clinical practice with research analytics equips him with the tools to contribute effectively to modern healthcare challenges. His publications in peer-reviewed journals, collaborations with international organizations, and active participation as a scientific reviewer showcase his influence and potential in the global research community. While there is room for growth in terms of international exposure and leadership in large-scale research initiatives, Osman has laid a strong foundation for a distinguished career. His ongoing pursuit of a PhD signals a forward-thinking approach to medical research and innovation. Overall, Osman’s combination of academic diligence, hands-on experience, humanitarian engagement, and research acumen make him a valuable contender for prestigious research recognitions such as the Best Researcher Award.

Publications Top Notes

1. Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in Wad Madani Teaching Hospital, 2024: A Cross‐Sectional Study

  • Journal: Health Science Reports

  • Year: 2025

  • Authors: Eltype Elsiddig, Alaaeldeen Alhassan, Osman Amir, Moawia Elbalal

2. The Five-Years Overall Survival and Recurrence Free Survival of Neoadjuvant Systemic Therapy in Breast Cancer Sudanese Patients: A Retrospective Comparative Study [Version 1; Peer Review: 1 Approved]

  • Journal: F1000Research

  • Year: 2025

  • Authors: Tamador Elhadi Osman, Ayda Hussein Omer Mustafa, Rayan Ali Abdalla, Osman Amir, Hamid Ali Abd Alrahman, Abd Alrahman Hamid Ali, et al.

3. Assessment of the Knowledge on Insulin Therapy Among Adult Diabetics Patients in Jabir Abuleiz Center, Khartoum, Sudan

  • Journal: Journal of Family Medicine and Primary Care

  • Year: 2022

  • Authors: Osman Amir

4. The Characteristics and Outcomes of COVID‐19 Among Diabetic Patients in Wad‐Medani Isolation Center From September to December 2020: A Cross‐Sectional Study

  • Journal: Health Science Reports

  • Year: 2022

  • Authors: Maali Mustafa, Alaaeldeen Attaallah, Osman Amir, Moawia Elbalal, Abdallah Abd AL‐Kareem Gibriel

5. Detection of Helicobacter pylori (H. pylori) by Histochemical Stains in Gastric Biopsy Comparing to Immunohistochemistry

  • Journal: World Journal of Advanced Research and Reviews

  • Year: 2022

  • Authors: Osman Amir

6. Platelet-Lymphocyte Ratio (PLR) in Post Renal Transplant Patients, Khartoum State, 2021

  • Journal: American Journal of Research Communication

  • Year: 2021

  • Authors: Osman Amir

7. The Prognostic Value of Thrombocytopenia in COVID-19 Pneumonia, Gezira Isolation Centers, Sudan

  • Journal: International Journal of Research and Reports in Hematology

  • Year: 2021

  • Authors: Osman Amir

8. The Neurological Manifestation in COVID-19 Patients in Gezira COVID-19 Isolation Centre

  • Journal: International Neuropsychiatric Disease Journal

  • Year: 2021

  • Authors: Osman Amir