Prof. Ashish Kumar Tewari | Medicinal Chemistry | Best Research Award

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Prof. Ashish Kumar Tewari | Medicinal Chemistry | Best Research Award

Professor at Medicinal Chemistry, Department of Chemistry Institute of Science Banaras Hindu University Varanasi 221005 INDIA

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🏆 The awards and recognitions, including the First Place in the Poster Award at the University of Stavanger, underscore the impact of your research and the high regard it holds in the academic community.

Professional Profiles:

Education:

Prof. Ashish Kumar Tewari holds a Ph.D. in Synthetic Organic Chemistry from Lucknow University, Lucknow, India, awarded in 2000. He completed his M.Sc. in Organic Chemistry from Kanpur University, with studies at F. G. College Raebareli, in 1993. His undergraduate degree, a B.Sc. in Chemistry and Physics, was obtained from Lucknow University (BSNV Degree College) in 1991.

Research Work:

Prof. Ashish Kumar Tewari is currently an Associate Professor in the Department of Chemistry at Banaras Hindu University, Varanasi, India. His research focuses on Molecular Recognition and Medicinal Chemistry. His work involves synthesizing bioactive molecules, flexible molecules with aromatic backbones, and foldamers to study aromatic interactions. Since approximately 20% of amino acids are aromatic, understanding aromatic interactions is crucial in drug-receptor interactions. His research group is actively involved in synthesizing pyrazole, imidazole, pyridine, and pyridazine systems, yielding interesting results such as solid-state eclipsed and staggered stacked conformations. Their work is reflected in their publications, with ongoing research yet to be published.

Post Doctoral Research Work:

During his postdoctoral research, Prof. Ashish Kumar Tewari worked at the Central Drug Research Institute (CDRI) in Lucknow, UP, India, as a CSIR Research Associate. His project focused on “Stereochemical control in aliphatic compounds by aromatic residues,” involving the synthesis of Pyrazolo[3,4-d]pyrimidine. This compound is isomeric to purine found in biological systems and serves as a model to study intra- and inter-molecular interactions important in drug-receptor interactions. He also worked as a Research Associate at the Indian Institute of Technology (IIT) in Mumbai, India, in the Department of Chemistry. His research there involved synthesizing monomers like triacytelene to prepare polydiacytelenes with aromatic backbones such as quinoline. This process included Suzuki coupling reaction followed by hydrolysis, leading to solid-state polymerization initiated thermally, photochemically, or by γ-irradiation. Recent interest in polydiacytelenes (PDAs) lies in their large and fast non-linear optical response, making them promising for applications in ultrafast optical signal processing.

Teaching Professional Work:

Prof. Ashish Kumar Tewari has held various positions in academia and the pharmaceutical industry. Since June 14, 2019, he has been serving as a Professor in the Department of Chemistry at Banaras Hindu University (BHU) in Varanasi, a Central University in India. Prior to this role, from June 14, 2016, to June 13, 2019, he was an Associate Professor in the same department, with a pay scale of Rs. 37400-67000/- plus AGP Rs. 9000. Before that, from June 14, 2004, to June 13, 2016, he served as an Assistant Professor (Senior Grade) at BHU, with a pay scale of Rs. 15600-39100/- plus AGP Rs. 7000. In these academic positions, his responsibilities included teaching undergraduate (UG) and postgraduate (PG) classes, as well as conducting research. Prior to his academic career, from September 3, 2003, to June 11, 2004, he worked as a Research Scientist at Lupin Research Park, a pharmaceutical industry research center, where he was involved in research activities.

Publications:

  1. Relationship between structure and inhibition behaviour of quinolinium salts for mild steel corrosion: Experimental and theoretical approach
    • Authors: MMS Punita Mourya, Praveen Singh, A.K. Tewari, R.B. Rastogi
    • Journal: Corrosion Science
    • Volume: 95
    • Pages: 71-87
    • Year: 2015
    • Citations: 195
  2. Synthesis and anti-inflammatory activities of N4, N5-disubstituted-3-methyl-1H-pyrazolo [3, 4-c] pyridazines
    • Authors: AK Tewari, A Mishra
    • Journal: Bioorganic & medicinal chemistry
    • Volume: 9
    • Issue: 3
    • Pages: 715-718
    • Year: 2001
    • Citations: 188
  3. Emerging trends in molecular recognition: utility of weak aromatic interactions
    • Authors: AK Tewari, R Dubey
    • Journal: Bioorganic & Medicinal Chemistry
    • Volume: 16
    • Issue: 1
    • Pages: 126-143
    • Year: 2008
    • Citations: 139
  4. Synthesis and antiviral activities of N-substituted-2-substituted-benzimidazole derivatives
    • Authors: AK Tewari, A Mishra
    • Source: CSIR
    • Year: 2006
    • Citations: 132
  5. Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents
    • Authors: AK Tewari, VP Singh, P Yadav, G Gupta, A Singh, RK Goel, P Shinde, …
    • Journal: Bioorganic chemistry
    • Volume: 56
    • Pages: 8-15
    • Year: 2014
    • Citations: 94
  6. Design, synthesis, docking and anti-inflammatory evaluation of novel series of benzofuran based prodrugs
    • Authors: P Yadav, P Singh, AK Tewari
    • Journal: Bioorganic & medicinal chemistry letters
    • Volume: 24
    • Issue: 10
    • Pages: 2251-2255
    • Year: 2014
    • Citations: 82
  7. Novel anti-inflammatory agents based on pyrazole based dimeric compounds; design, synthesis, docking and in vivo activity
    • Authors: AK Tewari, P Srivastava, VP Singh, A Singh, RK Goel, CG Mohan
    • Journal: Chemical and Pharmaceutical Bulletin
    • Volume: 58
    • Issue: 5
    • Pages: 634-638
    • Year: 2010
    • Citations: 71
  8. Quantum chemical calculation studies for interactions of antiwear lubricant additives with metal surfaces
    • Authors: V Jaiswal, RB Rastogi, JL Maurya, P Singh, AK Tewari
    • Journal: RSC Advances
    • Volume: 4
    • Issue: 26
    • Pages: 13438-13445
    • Year: 2014
    • Citations: 35
  9. Docking, synthesis and evaluation of antioxidant activity of 2, 4, 5-triaryl imidazole
    • Authors: P Singh, R Kumar, S Tiwari, RS Khanna, AK Tewari, HD Khanna
    • Journal: Clin. Med. Biochem. Open Access
    • Volume: 1
    • Pages: 105
    • Year: 2015
    • Citations: 34
  10. Cascade synthesis of 2-pyridones using acrylamides and ketones
    • Authors: SK Rai, S Khanam, RS Khanna, AK Tewari
    • Journal: RSC Advances
    • Volume: 4
    • Issue: 83
    • Pages: 44141-44145
    • Year: 2014
    • Citations: 30