Xin Wang | Pharmaceutical Science | Best Researcher Award

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Assoc Prof Dr. Xin Wang | Pharmaceutical Science | Best Researcher Award

Assoc. Professor and PhD supervisor of Shanghai Jiao Tong University, China.

Xin Wang is a Tenure-Track Associate Professor at Shanghai Jiao Tong University, specializing in pharmaceutical and biomedical analysis. He earned his Ph.D. in Analytical Chemistry from Peking University and completed postdoctoral work at MIT and UC Berkeley. His research focuses on mass spectrometry, metabolomics, and proteomics, with key projects including drug metabolism analysis, human neurogenesis studies, and advanced sample preparation techniques. Wang’s contributions have garnered several awards, such as the Shanghai Pujiang Talent Plan Award and recognition at MIT. His expertise in analytical techniques and innovative methods has significantly impacted both academic research and industry practices.

Professional Profiles:

Education

Xin Wang completed his B.Sc. in Chemistry at Wuhan University, China, in 2010. He pursued his Ph.D. in Analytical Chemistry at Peking University, graduating in 2015. Following his doctoral studies, Dr. Wang undertook postdoctoral research at the Massachusetts Institute of Technology (MIT) from 2015 to 2018. Since 2020, he has been serving as a Tenure-Track Associate Professor at the School of Pharmaceutical Sciences, Shanghai Jiao Tong University, China.

Professional Experience

Xin Wang’s professional experience includes a significant role as a Tenure-Track Associate Professor at the School of Pharmaceutical Sciences, Shanghai Jiao Tong University, where he has been since 2020. Before this, he was a Senior Postdoctoral Associate at MIT’s Department of Biological Engineering from 2018 to 2019, and a Postdoctoral Associate in the same department from 2015 to 2018. His earlier academic journey includes a Ph.D. in Analytical Chemistry from Peking University, where he also worked as a Visiting Graduate Student at UC Berkeley.

Research Interest

Xin Wang’s research interests are at the forefront of pharmaceutical and biomedical analysis, emphasizing the use of advanced analytical techniques. His work primarily focuses on mass spectrometry and its applications in drug metabolism and toxicity testing, aiming to replace traditional trials with in vitro human systems. He is also deeply engaged in metabolomics and proteomics, using these techniques to unravel metabolic features in human neurogenesis and other physiological processes. Wang has developed innovative methods in solid-phase microextraction to enhance the sensitivity and accuracy of analyzing low-molecular-mass compounds. His research integrates these areas to advance understanding in drug testing, biomarker discovery, and the mechanistic insights into human health and disease. This multidisciplinary approach not only pushes the boundaries of analytical chemistry but also contributes to more effective and efficient drug development and disease treatment strategies.

Award and Honors

Xin Wang has received several prestigious awards and honors throughout his career. In 2023, he was recognized as an Outstanding Individual with Exceptional Contributions in Education by the School of Pharmacy at Shanghai Jiao Tong University. He also won the Second Prize in the Young Professor Teaching Skills Competition at Shanghai Jiao Tong University in 2022. Wang’s accolades include the Shanghai Overseas High-Level Talent Program Award and the Shanghai Pujiang Talent Plan Award, both in 2020. In 2016, he earned First Place in the MIT Center for Environmental Health Sciences Session. Additionally, he was awarded the First Prize in the Science and Technology Award from the China Association for Instrumental Analysis in 2015. Earlier achievements include the Aoqing Tang Scholarship (2015), the Brilliance Scholarship (2014), and multiple awards for his graduate research and innovation.

Research Skills

Xin Wang possesses advanced research skills in several key areas of analytical and biomedical science. His expertise includes pharmaceutical and biomedical analysis, utilizing techniques such as mass spectrometry, metabolomics, and proteomics to study complex biological systems. He is proficient in solid-phase microextraction and has developed innovative methods for capturing and quantifying low-molecular-mass compounds. Wang’s work with time-dependent metabolomics and LC-MS-based quantitation reflects his ability to apply cutting-edge analytical techniques to understand human neurogenesis and drug metabolism. His research in automated sample preparation and ambient mass spectrometry demonstrates his skills in developing novel methodologies for high-sensitivity detection and analysis. Wang’s contributions to bioanalytical strategies and experimental design have been recognized and published in top scientific journals, showcasing his ability to push the boundaries of current research methodologies.

Publications

  1. “Mass spectrometry‐based metabolomics for the investigation of antibiotic–bacterial interactions”
    • Authors: Xin Wang
    • Year: 2024
  2. “A new approach towards highly sensitive detection of endogenous N-acetylaspartic acid, N-acetylglutamic acid, and N-acetylaspartylglutamic acid in brain tissues based on strong anion exchange monolith microextraction coupled with UHPLC-MS/MS”
    • Authors: Xin Wang
    • Year: 2024
  3. “Mass spectrometry-based quantitation combined with time-dependent metabolomics to discover metabolic features in human neurogenesis using neural constructs generated from neural progenitor cells”
    • Authors: Xin Wang
    • Year: 2023
  4. “Mass spectrometry analysis of S-nitrosylation of proteins and its role in cancer, cardiovascular and neurodegenerative diseases”
    • Authors: Xin Wang
    • Year: 2022
  5. “Low Doses of Arsenic in a Mouse Model of Human Exposure and in Neuronal Culture Lead to S-Nitrosylation of Synaptic Proteins and Apoptosis via Nitric Oxide”
    • Authors: Xin Wang
    • Year: 2020
  6. “Analysis of an Integrated Human Multiorgan Microphysiological System for Combined Tolcapone Metabolism and Brain Metabolomics”
    • Authors: Xin Wang
    • Year: 2019
  7. “Automated Online Solid-Phase Derivatization for Sensitive Quantification of Endogenous S-Nitrosoglutathione and Rapid Capture of Other Low-Molecular-Mass S-Nitrosothiols”
    • Authors: Xin Wang
    • Year: 2018
  8. “Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function”
    • Authors: Xin Wang
    • Year: 2018
  9. “Fast analysis of glycosides based on HKUST-1-coated monolith solid-phase microextraction and direct analysis in real-time mass spectrometry”
    • Authors: Xin Wang
    • Year: 2017
  10. “Polymer‐based monolithic column with incorporated chiral metal–organic framework for enantioseparation of methyl phenyl sulfoxide using nano‐liquid chromatography”
    • Authors: Xin Wang
    • Year: 2016