Rui Wen | Molecular Biology | Best Researcher Award

Assist. Prof. Dr. Rui Wen | Molecular Biology | Best Researcher Award

Assistant Professor Dr at Wenzhou Medical University, China

Rui Wen, an Assistant Professor at Wenzhou Medical University in China, has focused on advancing research in biomaterials, with a special interest in silk proteins for drug delivery systems. Since earning his PhD in Biomaterials from Donghua University in 2020, Rui has quickly established a reputable profile through his publications in high-impact journals and his role in editorial positions. His work encompasses essential biological processes like protein function, alternative splicing, and gene expression, with an emphasis on the use of silk-based materials for medical applications. Rui is actively involved in peer-reviewed publications, authoring eight first-author or corresponding-author articles in prominent journals over the past five years. Additionally, he has contributed to the scientific community by serving as an editorial board member and reviewer for multiple journals, illustrating his influence and expertise in the field of biomaterials.

Professional Profile

Education

Rui Wen completed his PhD in Biomaterials at Donghua University in 2020, where he focused on the biological functions of protein materials, especially silk-based biomaterials for drug delivery. His doctoral research established foundational insights into protein functionality and biomimetic applications, shaping his future focus on protein function and genetic analysis. Throughout his education, Rui developed a sophisticated understanding of biomaterials science, from molecular genetics to applications in medical technology. His PhD laid a robust academic and technical foundation, equipping him with the essential research methodologies and laboratory skills needed to contribute meaningfully to the biomaterials field. The strong academic training he received at Donghua University, combined with hands-on experience in research, has been instrumental in his transition to his current role as an Assistant Professor, where he continues to leverage his expertise in gene expression and protein function.

Professional Experience

Rui Wen’s professional journey as an Assistant Professor at Wenzhou Medical University began shortly after he completed his PhD. In this role, Rui has focused his research on developing silk-based biomaterials for medical applications, such as drug delivery. His work often involves collaborations with other experts in the biomaterials and genetic research fields, emphasizing protein functionality and biomimetic design. Rui’s academic contributions include publishing eight peer-reviewed papers as the first or corresponding author in recognized journals, including Acta Biomaterialia and the International Journal of Biological Macromolecules. These achievements highlight his commitment to advancing scientific knowledge in biomaterials. Additionally, Rui serves on editorial boards for journals like the World Journal of Biological Chemistry, further underscoring his dedication to scientific excellence and community engagement. His involvement in these roles signifies his professional growth and increasing impact within the scientific community.

Research Interests

Rui Wen’s research interests are centered on protein function, gene expression, and biomaterials, particularly focusing on the medical potential of silk-based proteins. He is intrigued by the genetic underpinnings of protein function and the application of alternative splicing in creating materials that mimic biological functions. His work has a dual focus: understanding protein behavior at a genetic level and leveraging this knowledge to develop innovative biomaterials for drug delivery. This focus on silk-based proteins, a biologically compatible and robust material, has led Rui to explore how protein sequences can be harnessed to design highly specialized biomaterials with practical medical applications. Rui’s research aims to integrate genetic insights with material science to produce versatile, biocompatible materials that can advance drug delivery and other medical therapies, contributing to new solutions in biotechnology and healthcare.

Research Skills

Rui Wen possesses extensive research skills in biomaterials science and protein analysis. His expertise includes characterizing protein functionality, analyzing gene sequences, and applying genetic engineering principles to create innovative materials. Rui has a strong background in protein biochemistry and molecular biology, which has enabled him to identify and engineer silk proteins for biomimetic applications. Additionally, he is skilled in alternative splicing and concerted evolution, both of which play a crucial role in his work with gene expression. Rui’s laboratory skills include various analytical techniques, such as protein characterization assays, molecular modeling, and genetic sequencing. His ability to publish consistently in peer-reviewed journals reflects his proficiency in scientific communication and data analysis. Furthermore, his role as a reviewer and editor highlights his critical assessment skills, making him a valuable contributor to the scientific community.

Awards and Honors

Rui Wen’s contributions to biomaterials science have been recognized through multiple awards and honors. He received funding from the China Postdoctoral Science Foundation, a competitive grant that supports emerging researchers in China. This funding enabled him to continue his exploration of silk-based proteins and their applications in drug delivery. His role on the editorial boards of respected journals like the World Journal of Biological Chemistry and Biomedical Engineering Communications is another notable achievement, reflecting the respect he has earned among his peers. In addition, his status as an invited reviewer for journals such as the International Journal of Biological Macromolecules demonstrates his expertise and the high regard of the scientific community. These honors underscore Rui’s dedication to advancing biomaterials science and highlight his influence in the fields of protein function and gene expression.

Conclusion

Rui Wen is a dedicated and promising researcher whose accomplishments in the specialized areas of protein function and biomaterials are commendable for someone early in their career. His expertise, consistent publication record, and increasing engagement with the scientific community through editorial and reviewing activities make him a competitive candidate for the Best Researcher Award. With further developments in his citation impact and expanded international collaborations, Rui Wen’s contributions are likely to gain even greater visibility and influence, establishing him as a key figure in biomaterials research.

Publications Top Notes

  1. Title: Physical Properties of the Second Type of Aciniform Spidroin (AcSp2) from Neoscona theisi Reveal a pH-Dependent Self-Assembly Repetitive Domain
    Authors: Yang, D., Wang, S., Wang, K., Zan, X., Wen, R.
    Journal: ACS Biomaterials Science and Engineering
    Year: 2023
    Volume(Issue): 9(12)
    Pages: 6670–6682
    Citations: 1
  2. Title: Complete Gene Sequence and Mechanical Property of the Fourth Type of Major Ampullate Silk Protein
    Authors: Wen, R., Wang, S., Wang, K., Zan, X., Meng, Q.
    Journal: Acta Biomaterialia
    Year: 2023
    Volume: 155
    Pages: 282–291
    Citations: 4
  3. Title: Characterization of Two Full-Length Tubuliform Silk Gene Sequences from Neoscona theisi Reveals Intragenic Concerted Evolution and Multiple Copies in Genome
    Authors: Wen, R., Wang, K., Zan, X.
    Journal: International Journal of Biological Macromolecules
    Year: 2022
    Volume: 223
    Pages: 1015–1023
    Citations: 3
  4. Title: Characterization of Two Full-Length Araneus ventricosus Major Ampullate Silk Protein Genes
    Authors: Wen, R., Yang, D., Wang, K., Zan, X.
    Journal: International Journal of Biological Macromolecules
    Year: 2022
    Volume: 213
    Pages: 297–304
  5. Title: The Novel Aciniform Silk Protein (AcSp2-v2) Reveals the Unique Repetitive Domain with High Acid and Thermal Stability and Self-Assembly Capability
    Authors: Wen, R., Wang, K., Yang, D., Zan, X., Meng, Q.
    Journal: International Journal of Biological Macromolecules
    Year: 2022
    Volume: 202
    Pages: 91–101
    Citations: 6
  6. Title: Customized Flagelliform Spidroins Form Spider Silk-Like Fibers at pH 8.0 with Outstanding Tensile Strength
    Authors: Li, X., Qi, X., Cai, Y.-M., Meng, Q., Chen, G.
    Journal: ACS Biomaterials Science and Engineering
    Year: 2022
    Volume(Issue): 8(1)
    Pages: 119–127
    Citations: 14
  7. Title: Characterization of the Second Type of Aciniform Spidroin (AcSp2) Provides New Insight into Design for Spidroin-Based Biomaterials
    Authors: Wen, R., Wang, K., Meng, Q.
    Journal: Acta Biomaterialia
    Year: 2020
    Volume: 115
    Pages: 210–219
    Citations: 16
  8. Title: Two Novel Tubuliform Silk Gene Sequences from Araneus ventricosus Provide Evidence for Multiple Loci in Genome
    Authors: Wen, R., Wang, K., Meng, Q.
    Journal: International Journal of Biological Macromolecules
    Year: 2020
    Volume: 160
    Pages: 806–813
    Citations: 10
  9. Title: Wet-Spinning Synthetic Fibers from Aggregate Glue: Aggregate Spidroin 1 (AgSp1)
    Authors: Li, X., Mi, J., Wen, R., Meng, Q., Lin, Y.
    Journal: ACS Applied Bio Materials
    Year: 2020
    Volume(Issue): 3(9)
    Pages: 5957–5965
    Citations: 10
  10. Title: Novel Highly Soluble Chimeric Recombinant Spidroins with High Yield
    Authors: Jia, Q., Wen, R., Meng, Q.
    Journal: International Journal of Molecular Sciences
    Year: 2020
    Volume(Issue): 21(18)
    Pages: 1–13, Article ID: 6905
    Citations: 11

Estefanía Saez Lancellotti | Molecular Biology | Women Researcher Award

Dr. Estefanía Saez Lancellotti | Molecular Biology | Women Researcher Award

Investigator Senior at IBIMA, Spain.

Estefanía Saez Lancellotti is a senior postdoctoral researcher at IBIMA, Spain, with a PhD in Cellular, Molecular, and Neurosciences from the University of Chile. Her research focuses on molecular biology, genetics, and lipid metabolism, with an emphasis on reproductive biology and male fertility. She has published 16 papers in the Web of Science Core Collection, 12 of which are in Q1 journals, and her work has received 411 citations, earning her an h-index of 9. Estefanía has led five research projects and actively participates in scientific committees and R&D activities. She has presented at 141 conferences, supervised four doctoral theses (two completed), and earned multiple awards and distinctions for her contributions. Her work on the impact of lipid diets on spermatogenesis and male infertility has been recognized internationally, positioning her as a leading researcher in her field.

Profile:

Education

Estefanía Saez Lancellotti holds a Licenciatura in Molecular Biology from the University of San Luis, Argentina, which she completed in 2001. She later pursued a PhD in Sciences with a specialization in Cellular, Molecular, and Neurosciences at the University of Chile, obtaining her degree in 2006. Estefanía continued her academic journey with postdoctoral research at the National Scientific and Technical Research Council (CONICET) and the Institute of Histology and Embryology of Mendoza (IHEM) in Argentina, where she completed two Postdoctoral Fellowships between 2009 and 2011. These postdoctoral studies significantly enhanced her expertise in molecular biology and genetics, laying the foundation for her future research in lipid metabolism and male fertility. Estefanía’s academic qualifications and extensive postdoctoral training have provided her with a solid foundation in her field, allowing her to contribute significantly to scientific research and advancements in reproductive biology.

Professional Experience

Estefanía Saez Lancellotti is a seasoned researcher with a robust background in molecular biology, cellular biology, and genetics. She is currently a Senior Postdoctoral Researcher at IBIMA (Biomedical Research Institute of Málaga), working at the Hospital Civil in Andalucía, Spain, since July 2023. Prior to this, she served as an Adjunct Researcher at the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) in Argentina from 2010 to 2023, where she contributed significantly to scientific advancements in reproductive biology. Over the course of her career, Estefanía has led five I+D projects, collaborated on numerous research initiatives, and participated in over 141 congress presentations. Her leadership extends to doctoral supervision, guiding two PhD students to completion, with two more currently under her mentorship. Estefanía’s work has garnered international recognition, contributing to impactful research on lipid metabolism and male fertility.

Research Interest

Estefanía Saez Lancellotti’s research interests lie at the intersection of molecular biology, reproductive health, and lipid metabolism, with a specific focus on how diet and metabolic factors influence male fertility. Her work explores the impact of lipid stress and hypercholesterolemia on the spermatogenesis process, utilizing advanced molecular and cellular techniques. She has contributed significantly to understanding the role of dietary interventions, particularly the effects of extra virgin olive oil, in reversing the negative impacts of high-fat diets on male reproductive health. Estefanía is also keenly involved in omic studies related to sperm cytoskeleton alterations and damage reversal strategies. Her research has important implications for infertility treatments and chronic disease management linked to dietary and metabolic disorders. Collaborating with international institutions, she leads innovative projects aimed at improving male reproductive health through targeted nutritional and molecular interventions.

Research Skills

Estefanía Saez Lancellotti demonstrates a robust set of research skills, particularly in molecular biology, cellular biology, and genetics. Her expertise spans designing and leading innovative research projects, with a focus on lipid metabolism, male infertility, and dietary interventions. She is adept in conducting complex -omic studies, utilizing advanced techniques in genomics and proteomics to explore the effects of lipid stress on sperm cytoskeleton and reproductive health. With a proven ability to secure competitive funding, Estefanía has led multiple high-impact I+D projects and published extensively in Q1 journals. Her strong collaboration skills are evidenced by her roles as Principal Investigator (IP) and co-leader of interdisciplinary teams. She also possesses excellent mentorship abilities, supervising both doctoral and undergraduate theses. Her work has garnered over 400 citations, demonstrating the global relevance and influence of her research in reproductive biology and molecular sciences.

Award and Recognition

Estefanía Saez Lancellotti has received significant recognition for her contributions to molecular biology and reproductive health research. She has been honored with five awards, mentions, and distinctions, underscoring her excellence in scientific innovation and academic leadership. Her work on the impact of lipid metabolism on male fertility, particularly in relation to dietary interventions, has been widely recognized. Estefanía’s research achievements include 12 publications in Q1 journals, reflecting the high impact and quality of her work. As the Principal Investigator (PI) of several prestigious I+D projects, she has demonstrated strong leadership in advancing scientific knowledge. Additionally, her role in organizing and participating in 141 conferences and her supervision of doctoral theses have further established her as a prominent figure in her field. Estefanía’s commitment to groundbreaking research has earned her a respected place within the international scientific community.

Conclusion

Estefanía Saez Lancellotti’s scientific output, leadership in research projects, and international collaborations make her a strong contender for the Best Researcher Award. Her focus on impactful research areas such as male fertility and lipid metabolism, combined with her involvement in high-level scientific activities, showcases her excellence in the field. However, increasing the citation impact, securing higher project funding, and further expanding her doctoral supervision could further elevate her candidacy for top research awards.

Publication Top Notes

  1. Extra-virgin olive oil ameliorates high-fat diet-induced seminal and testicular disorders by modulating the cholesterol pathway
    • Authors: Funes, A.K.; Avena, M.V.; Ibañez, J.; Fornés, M.W.; Saez Lancellotti, T.E.
    • Year: 2023
    • Journal: Andrology, 11(6), pp. 1203–1217
    • Citations: 3
  2. Impact of high-fat diet on the sterol regulatory element-binding protein 2 cholesterol pathway in the testicle
    • Authors: Funes, A.K.; Simón, L.; Colombo, R.; Fornes, M.W.; Saez Lancellotti, T.E.
    • Year: 2021
    • Journal: Molecular Human Reproduction, 27(5), gaab023
    • Citations: 6
  3. ODF1, sperm flagellar protein is expressed in kidney collecting ducts of rats
    • Authors: Cabrillana, M.E.; Bocanegra, V.; Monclus, M.A.; Oliva, R.; Fornés, M.W.
    • Year: 2019
    • Journal: Heliyon, 5(12), e02932
    • Citations: 3
  4. Olive oil addition to the high-fat diet reduces methylglyoxal (MG-H1) levels increased in hypercholesterolemic rabbits
    • Authors: Simon, L.; Lancellotti, T.E.S.; Cortese, L.; Barbieri, A.; Fornes, M.
    • Year: 2019
    • Journal: Mediterranean Journal of Nutrition and Metabolism, 12(1), pp. 13–21
    • Citations: 2
  5. Pigment epithelium-derived factor (PEDF) expression in the male tract of Wistar rats
    • Authors: Conte, M.I.; Cabrillana, M.E.; Saez Lancellotti, T.E.; Fornes, M.W.; Monclus, M.A.
    • Year: 2018
    • Journal: Biochemical and Biophysical Research Communications, 504(1), pp. 257–262
    • Citations: 4
  6. Manchette-acrosome disorders and testicular efficiency decline observed in hypercholesterolemic rabbits are recovered with olive oil enriched diet
    • Authors: Simón, L.; Funes, A.K.; Monclús, M.A.; Saez Lancellotti, T.E.; Fornés, M.W.
    • Year: 2018
    • Journal: PLoS ONE, 13(8), e0202748
    • Citations: 8
  7. Manchette-acrosome disorders during spermiogenesis and low efficiency of seminiferous tubules in hypercholesterolemic rabbit model
    • Authors: Simón, L.; Funes, A.K.; Yapur, M.A.; Lancellotti, T.E.S.; Fornés, M.W.
    • Year: 2017
    • Journal: PLoS ONE, 12(2), e0172994
    • Citations: 15
  8. Thiols of flagellar proteins are essential for progressive motility in human spermatozoa
    • Authors: Cabrillana, M.E.; Monclus, M.D.L.A.; Lancellotti, T.E.S.; Sanabria, E.A.; Fornés, M.W.
    • Year: 2017
    • Journal: Reproduction, Fertility and Development, 29(7), pp. 1435–1446
    • Citations: 11
  9. Semen Quality and Sperm Function Loss by Hypercholesterolemic Diet Was Recovered by Addition of Olive Oil to Diet in Rabbit
    • Authors: Saez Lancellotti, T.E.; Boarelli, P.V.; Romero, A.A.; Vicenti, A.E.; Fornés, M.W.
    • Year: 2013
    • Journal: PLoS ONE, 8(1), e52386
    • Citations: 46
  10. SPINK3 modulates mouse sperm physiology through the reduction of nitric oxide level independently of its trypsin inhibitory activity
    • Authors: Zalazar, L.; Saez Lancellotti, T.E.; Clementi, M.; Fornés, M.W.; Cesari, A.
    • Year: 2012
    • Journal: Reproduction, 143(3), pp. 281–295
    • Citations: 22