Dr. Binbin Ma | Agricultural and Biological Sciences | Best Researcher Award
HHMI/Johns Hopkins University, United States.
Binbin Ma is a distinguished researcher specializing in epigenetic inheritance and stem cell biology. Currently a postdoctoral researcher at Howard Hughes Medical Institute/Johns Hopkins University, his work focuses on the molecular mechanisms underlying histone inheritance and cell fate determination. With a Ph.D. from Shanghai Jiao Tong University and extensive postdoctoral experience at Johns Hopkins University, Ma has made significant contributions to understanding epigenetic regulation. His research has led to high-impact publications in journals like Cell and Nature Communications, and he has been recognized with awards such as the Joseph Li Travel Award. Ma’s work is instrumental in advancing knowledge in cell biology and has potential applications in regenerative medicine. His global research experience, collaborative efforts, and numerous accolades highlight his role as a leading researcher in his field.
Education🎓
Binbin Ma’s educational journey reflects a robust foundation in stem cell biology and epigenetics. He completed his Ph.D. in Germline Stem Cell Biology at the Bio-X Institute of Shanghai Jiao Tong University in China (2013-2019), where he focused on the isolation, culture, and transplantation of germline stem cells, as well as single-cell RNA sequencing analysis. Prior to this, he earned an M.S. in Clinical Veterinary Medicine with a specialization in Embryo Engineering from North-West A&F University, China (2010-2013), where he gained expertise in mouse embryo manipulation and micromanipulation. Additionally, Binbin Ma broadened his research perspective as a Visiting Student in Stem Cells and Epigenetics at Johns Hopkins University (2015-2017), contributing to his deep understanding of differential histone inheritance patterns. His postdoctoral training at Johns Hopkins University and Howard Hughes Medical Institute further advanced his expertise in epigenetic inheritance in mammalian stem cells.
Binbin Ma has built an impressive professional career in the field of stem cell biology and epigenetics. Currently a Postdoctoral Fellow at the Howard Hughes Medical Institute/Johns Hopkins University, Ma investigates epigenetic inheritance in mammalian stem cells, a critical area of research for understanding cell fate determination. Previously, he held a similar position at Johns Hopkins University’s Department of Biology, where he continued his work on epigenetic inheritance under the guidance of Drs. Xin Chen and Haiqing Zhao. Ma earned his Ph.D. from Shanghai Jiao Tong University, focusing on germline stem cell biology. His professional journey includes a visiting student role at Johns Hopkins, where he explored differential histone inheritance patterns. Ma’s early career involved advanced training in clinical veterinary medicine and embryo engineering at North-West A & F University. His diverse and multidisciplinary experience highlights his expertise and dedication to advancing scientific knowledge.
Environmental Health
While Binbin Ma’s research is primarily focused on epigenetics and stem cell biology, it holds potential indirect implications for environmental health. His investigations into histone inheritance and cell fate determination can provide insights into how environmental factors may influence genetic and epigenetic mechanisms. Understanding these interactions is crucial, as environmental exposures can affect cellular processes and contribute to various health outcomes. By elucidating the fundamental principles of cellular regulation and inheritance, Ma’s work could inform studies on how environmental pollutants and stressors impact biological systems. Although his research does not directly target environmental health, the underlying mechanisms explored in his studies have broader applications that could enhance our understanding of how environmental factors influence gene expression and contribute to health and disease.
Research Interests 🔬
Binbin Ma’s research interests are centered around epigenetic inheritance and stem cell biology, with a particular focus on understanding how histone modifications influence cell fate and development. His work delves into the molecular mechanisms underlying asymmetric histone inheritance, which is crucial for maintaining cellular identity and function across generations. Ma investigates these processes using various model organisms, including mice and human stem cells, to elucidate how epigenetic regulation impacts stem cell behavior and differentiation. His research aims to uncover the dynamic interactions between genetic and epigenetic factors in controlling cellular processes, which has implications for regenerative medicine and developmental biology. Through his studies, Ma seeks to bridge fundamental biological concepts with potential therapeutic applications, contributing to advancements in understanding cell biology and developing novel strategies for disease treatment.
Binbin Ma has earned several prestigious awards and honors throughout his academic career, reflecting his exceptional contributions to research in epigenetics and stem cell biology. Notably, he received the Joseph Li Travel Award at the SCBA 18th International Symposium in Boston in 2022, and the Best Poster Award at the SCBA meeting DC-Baltimore Chapter in 2021. His excellence as a graduate student was recognized with the Excellent Graduate award from Shanghai Jiao Tong University in 2019. Earlier achievements include the Scholarship of Hong Kong Moral Association in 2014 and multiple scholarships during his undergraduate studies at North-West A & F University and South-western University for Nationalities. These honors highlight his significant impact in the field and his commitment to advancing scientific knowledge.
Binbin Ma possesses advanced research skills that underscore his expertise in epigenetics and stem cell biology. His proficiency in designing and conducting complex experiments is demonstrated through his work on asymmetric histone inheritance and dynamic epigenetic regulation. Ma is adept at employing cutting-edge techniques, including single-cell RNA sequencing, to unravel intricate biological processes. His skills in data analysis are evident from his extensive list of high-impact publications, which reflect his ability to interpret and present complex research findings. Furthermore, Ma’s experience with diverse research models and his collaborative approach highlight his versatility and capability in integrating interdisciplinary methods. His commitment to rigorous scientific inquiry and innovation is reinforced by his successful execution of projects funded by prestigious institutions like NIH and Howard Hughes Medical Institute. Overall, Binbin Ma’s research skills are characterized by technical proficiency, analytical expertise, and a collaborative spirit, making him a leading figure in his field.
Conclusion
Binbin Ma’s extensive research experience, significant contributions to the field of epigenetics and stem cell biology, and his collaborative approach make him a strong candidate for the Research for Best Researcher Award. His work not only advances scientific knowledge but also holds potential for broader applications in medicine and biology. His achievements and recognition further underscore his suitability for this prestigious award.
- Protocol for Establishing Mouse Embryonic Stem Cells to Study Histone Inheritance Pattern at Single-Cell Resolution
- Authors: Binbin Ma
- Year: 2020
- Differential Histone Distribution Patterns in Induced Asymmetrically Dividing Mouse Embryonic Stem Cells
- Authors: Binbin Ma
- Year: 2020
- Progress on the Clinical Applications of Stem Cells for Thin Endometrium
- Authors: Binbin Ma
- Year: 2020
- Extended culture of day 3 embryos improves live birth rate in in vitro fertilization-embryo transfer
- Authors: Binbin Ma
- Year: 2019
- Molecular characteristics of early-stage female germ cells revealed by RNA sequencing of low-input cells and analysis of genome-wide DNA methylation
- Authors: Binbin Ma
- Year: 2018
- Progress on the Clinical Applications of Stem Cells for Premature Ovarian Failure
- Authors: Binbin Ma
- Year: 2018
- Improvement of pregnancy outcome by extending embryo culture in IVF-ET during clinical application
- Authors: Binbin Ma
- Year: 2018
- Dosage compensation in the process of inactivation/reactivation during both germ cell development and early embryogenesis in mouse
- Authors: Binbin Ma
- Year: 2017
- Enhancer of polycomb maintains germline activity and genome integrity in Drosophila testis
- Authors: Binbin Ma
- Year: 2017