Associate Researcher from Fudan University, China
Dr. Feixiang Yuan is an Associate Researcher at the Institute for Translational Brain Research, Fudan University, affiliated with Zhongshan Hospital. His research focuses on the central regulatory mechanisms of metabolic homeostasis, particularly the interplay between nutrient sensing, neuroendocrine signaling, and metabolic diseases. Dr. Yuan has made significant contributions to understanding how amino acid sensing in the brain influences systemic metabolism, with implications for conditions such as obesity, diabetes, and depression. His work has been published in high-impact journals, including Nature Communications, Proceedings of the National Academy of Sciences, and Diabetes. Through his research, Dr. Yuan aims to elucidate the neural circuits and molecular pathways that govern energy balance and metabolic health.
Professional Profile
Education
Dr. Yuan earned his Bachelor of Engineering in Food Science and Engineering from Ocean University of China in 2014. He then pursued doctoral studies at the University of Chinese Academy of Sciences, obtaining a Ph.D. in Physiology in 2019. His doctoral research was conducted at the Shanghai Institute of Biological Sciences, where he investigated the molecular mechanisms underlying metabolic regulation. This academic foundation provided him with a multidisciplinary perspective, integrating principles from food science, physiology, and molecular biology. Dr. Yuan’s educational background has equipped him with the skills necessary to explore complex biological systems and contribute to advancements in metabolic research.
Professional Experience
Following his Ph.D., Dr. Yuan completed a postdoctoral fellowship at the Institute of Nutrition and Health, Chinese Academy of Sciences, from 2019 to 2022. During this period, he focused on the central nervous system’s role in metabolic regulation, particularly how nutrient signals influence energy homeostasis. In 2022, he joined Fudan University as an Associate Researcher at the Institute for Translational Brain Research. In this role, Dr. Yuan leads research projects investigating the neural mechanisms of metabolic control, collaborating with interdisciplinary teams to translate basic research findings into potential therapeutic strategies for metabolic disorders.
Research Interests
Dr. Yuan’s research interests center on the central regulation of metabolic homeostasis. He investigates how the brain senses and responds to nutrient signals, particularly amino acids, and how these processes affect systemic metabolism. His work explores the neural circuits and molecular pathways involved in energy balance, glucose and lipid metabolism, and the development of metabolic diseases. By understanding the brain’s role in metabolic regulation, Dr. Yuan aims to identify novel targets for the treatment of conditions such as obesity, type 2 diabetes, and metabolic syndrome. His interdisciplinary approach combines neuroscience, physiology, and molecular biology to unravel the complex interactions between the central nervous system and peripheral metabolic processes.
Research Skills
Dr. Yuan possesses a robust set of research skills that enable him to conduct comprehensive studies on metabolic regulation. He is proficient in various molecular biology techniques, including gene expression analysis, protein assays, and genetic manipulation. His expertise extends to neuroanatomical methods, such as brain region-specific manipulations and neuronal activity mapping, allowing him to dissect neural circuits involved in metabolic control. Dr. Yuan is also skilled in metabolic phenotyping, including assessments of glucose tolerance, insulin sensitivity, and energy expenditure in animal models. His ability to integrate these methodologies facilitates a holistic understanding of the mechanisms governing energy homeostasis.
Awards and Honors
Dr. Yuan’s contributions to metabolic research have been recognized through various awards and honors. He has secured funding from the National Natural Science Foundation of China (NSFC) for multiple projects, serving as both principal investigator and co-investigator. His research excellence has been acknowledged by his peers, as evidenced by his publications in prestigious scientific journals. These accolades reflect Dr. Yuan’s commitment to advancing our understanding of metabolic regulation and his potential to make significant impacts in the field.
Conclusion
Dr. Feixiang Yuan is a dedicated researcher whose work bridges the gap between neuroscience and metabolism. His investigations into the central mechanisms of metabolic regulation have provided valuable insights into how the brain influences systemic energy balance. Through his interdisciplinary approach, Dr. Yuan has advanced our understanding of the neural control of metabolism, paving the way for novel therapeutic strategies for metabolic diseases. His continued research promises to contribute significantly to the field, making him a strong candidate for recognition as a leading researcher in metabolic science.
Publications Top Notes
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Title: Hypothalamic SLC7A14 accounts for aging-reduced lipolysis in white adipose tissue of male mice
Authors: Jiang, Xiaoxue; Liu, Kan; Luo, Peixiang; Ni, Shihong; Guo, Feifan
Journal: Nature Communications
Year: 2024
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Title: Inhibition of c-Jun in AgRP neurons increases stress-induced anxiety and colitis susceptibility
Authors: Jiao, Fuxin; Hu, Xiaoming; Yin, Hanrui; Liu, Zhanju; Guo, Feifan
Journal: Communications Biology
Year: 2023
Citations: 1