Dr. Alaa Alsalloum, Novosibirsk State University, Russia.
Dr. Alaa Alsalloum is a dedicated researcher in the fields of immunology and microbiology, known for her contributions to understanding immune responses and microbial interactions. With a strong commitment to excellence in research, she focuses on innovative approaches to tackle infectious diseases and enhance immunological health. Alaa’s work is characterized by a collaborative spirit and a passion for advancing scientific knowledge, making her a valuable asset in the pursuit of breakthroughs in health and disease management.
Profile:
Education
Alaa Alsalloum’s educational journey began at the National Center for Distinguished in Syria, where she completed high school from October 2011 to June 2014. She then earned her Bachelor of Science in Pharmacy from the University of Damascus, focusing on Biomedical Sciences, with a thesis titled “Phage Nanobody Immuno-PCR for Ultra-sensitive Detection of Growth Hormone (GH).” Following this, Alaa participated in a general education program at Kazan (Volga Region) Federal University to master professional educational programs in Russian from October 2018 to June 2019. She continued her studies at Kazan Federal University, where she completed her master’s degree in the Institute of Medicine and Biology, focusing on the earlier immune markers of multiple sclerosis in an animal model for her thesis. Currently, Alaa is pursuing her PhD at Novosibirsk State University, specializing in molecular immunology, with her research centered on the phenotypic and functional characteristics of T-lymphocytes with genetically modified antigen-recognizing receptors specific to solid tumor antigens.
Interests
Alaa Alsalloum is committed to community service, having volunteered with the Association for Persons with Special Needs (APSN) in Deir Atiyah, Syria, from July 2014 to September 2015. During her time there, she contributed to supporting individuals with special needs, helping to enhance their quality of life and promote inclusivity. This experience reflects her dedication to making a positive impact in the lives of others and highlights her passion for service beyond her academic pursuits.
Skills
Alaa Alsalloum possesses a robust set of technical skills acquired through her research in immunology and molecular biology during her Bachelor’s and Master’s theses. She is proficient in DNA and RNA extraction, PCR, electrophoresis, bacterial transformation, ELISA tests, immunochemistry, NanoString technology, and cell culture techniques. Additionally, she has experience with PBMC isolation, viral transduction of T-lymphocytes, dendritic cell differentiation protocols, tetramer assays, cell sorting protocols, flow cytometry, and intracellular flow cytometry staining. Alaa also has foundational knowledge in RT-PCR, cell analysis, Seahorse technology, 3D cell culture, and single-cell sequencing.On the interpersonal side, she has developed strong presentation and communication skills through participation in various seminars focused on communication and leadership. Alaa is adept at collaborating within a team while also demonstrating the ability to work independently, making her a well-rounded candidate in both research and professional settings.
Publication Top Notes
Alsalloum, A. (2024). NY‐ESO‐1 antigen: A promising frontier in cancer immunotherapy. Clinical and Translational Medicine. DOI: 10.1002/ctm2.70020. ISSN: 2001-1326.
Alsalloum, A. (2023). TCR-Engineered Lymphocytes Targeting NY-ESO-1: In Vitro Assessment of Cytotoxicity against Tumors. Biomedicines, 11(10), Article 2805. DOI: 10.3390/biomedicines11102805.
Alsalloum, A. (2023). Exploring TCR-like CAR-Engineered Lymphocyte Cytotoxicity against MAGE-A4. International Journal of Molecular Sciences, 24(20), Article 15134. DOI: 10.3390/ijms242015134.
Alsalloum, A. (2023). Immunoregulatory properties of erythroid nucleated cells induced from CD34+ progenitors from bone marrow. PLOS ONE, 18(6), Article e0287793. DOI: 10.1371/journal.pone.0287793. ISSN: 1932-6203.
Alsalloum, A. (2023). The Melanoma-Associated Antigen Family A (MAGE-A): A Promising Target for Cancer Immunotherapy? Cancers, 15(6), Article 1779. DOI: 10.3390/cancers15061779.
Alsalloum, A. (2022). Phenotypic and functional features of in vitro generated TCR-T cells specific for the tumor-associated antigen NY-ESO-1. Immunologiya, 43(5), 536-547. DOI: 10.33029/0206-4952-2022-43-5-536-547.
Alsalloum, A. (2022). Study of MAGE-A4 specific TCR-like CAR-T lymphocytes in vitro. Immunologiya, 43(4), 401-411. DOI: 10.33029/0206-4952-2022-43-4-401-411.