Xiuling Wang | Molecular Biology | Best Researcher Award

Dr. Xiuling Wang | Molecular Biology | Best Researcher Award

Department of Medical Laboratory from The Central Hospital of Wuhan, China

Xiuling Wang is a dedicated biomedical researcher and senior clinical laboratory professional currently serving as a Chief Technician at the Department of Laboratory Medicine, Wuhan Central Hospital, affiliated with Huazhong University of Science and Technology. With a doctoral degree in Pathogenic Biology from Wuhan University, she has consistently contributed to the field of immunology, particularly focusing on macrophage biology, neuroinflammation, and retroviral protein functions. Her publication record demonstrates a strong commitment to scientific advancement, with multiple articles featured in high-impact journals such as Metabolism, Immunology & Cell Biology, Archives of Virology, and Brain, Behavior and Immunity. While she has not held postdoctoral roles or national-level research grants, her independent research has made a significant impact in her specialized domain. She combines practical laboratory skills with theoretical insights to investigate inflammatory pathways and immune responses relevant to infectious and neurological diseases. Her work has implications in understanding immune regulation, epigenetics, and cellular signaling. With a balanced combination of laboratory practice and academic research, Xiuling Wang exemplifies the integration of clinical application with biomedical discovery. Her potential for future contributions remains high, especially if supported by expanded research funding and collaborative networks at national and international levels.

Professional Profile

Education

Xiuling Wang’s academic journey reflects a strong foundation in life sciences and biomedical research. She earned her Ph.D. in Pathogenic Biology from Wuhan University between September 2011 and December 2017. During her doctoral studies, she focused on understanding host-pathogen interactions and molecular mechanisms of immune regulation, which later shaped the core of her research interests. Her Ph.D. work laid the groundwork for exploring the functional roles of histone modification and endogenous retroviral proteins in inflammatory responses. Before pursuing her doctoral degree, she completed a Bachelor of Science in Biological Sciences at Shenyang Agricultural University from September 2007 to July 2011. This undergraduate program provided her with fundamental training in cellular biology, genetics, and microbiology. Her academic progression from a broad-based biological science education to a specialized doctoral study in pathogenic biology demonstrates a clear trajectory toward expertise in immunology and infectious disease research. Although she has not undertaken formal postdoctoral research, her doctoral education, combined with her clinical laboratory responsibilities, has enabled her to independently carry out impactful research. Her academic background continues to influence her scientific inquiry into macrophage activation, inflammatory signaling, and the epigenetic regulation of immune cells.

Professional Experience

Xiuling Wang has built her professional career primarily within Wuhan Central Hospital, affiliated with Huazhong University of Science and Technology, where she currently holds the role of Chief Technician in the Department of Laboratory Medicine. Since February 2020, she has been leading technical operations and contributing to both diagnostic and research activities in the clinical laboratory. Prior to this position, from December 2017 to January 2020, she served as a Technician in the same department. During these years, she has developed and refined her expertise in molecular diagnostics, cellular analysis, and immunological assays. Her clinical role complements her academic background, allowing her to bridge laboratory research with patient-centered diagnostics. Her work environment has enabled her to explore inflammatory responses, macrophage polarization, and immune regulation through both clinical samples and experimental models. Despite the lack of formal postdoctoral appointments or international placements, her responsibilities have encompassed advanced lab techniques, experiment design, and publication-driven research. She has proven her ability to produce high-quality scientific output independently, which speaks to her technical proficiency and analytical capability. Her career development within a university-affiliated hospital also highlights her commitment to integrating scientific inquiry into healthcare improvements.

Research Interests

Xiuling Wang’s research interests lie at the intersection of immunology, molecular biology, and virology, with a strong emphasis on inflammatory mechanisms and immune regulation. Her primary focus has been on the functional roles of endogenous retroviral proteins, histone modification enzymes, and transcription factors in mediating immune cell responses. She is particularly interested in how epigenetic regulators such as G9a and PCAF modulate macrophage polarization during lipid exposure and inflammation. Her investigations into proteins like Syncytin-1 and HERV-W env in glial cells further demonstrate her focus on neuroinflammation and innate immunity. These studies have direct implications for understanding the pathogenesis of neurodegenerative and autoimmune diseases. Additionally, her research seeks to elucidate the signaling cascades involving toll-like receptors (TLRs), MyD88, KLF2/4, and cytokine production in the central nervous system and peripheral immune tissues. Xiuling Wang is also interested in the translational application of these findings for diagnostics and therapeutic strategies. Her interdisciplinary interests span across disease biology, epigenetics, and immunopathology. By integrating experimental findings with clinical relevance, she aims to uncover novel mechanisms of immune dysfunction and offer potential biomarkers or targets for inflammatory diseases and neurological disorders.

Research Skills

Xiuling Wang possesses a wide array of research skills that make her proficient in conducting independent biomedical research. She has significant expertise in immunological techniques, including cytokine profiling, flow cytometry, and cell culture assays, which are critical for studying macrophage activity and inflammatory responses. Her experience also includes molecular biology techniques such as quantitative PCR, Western blotting, and RNA interference, allowing her to explore gene expression and protein regulation. She has used advanced imaging and immunohistochemistry tools in her analysis of glial cell activation. In addition, she is skilled in epigenetic assays that examine histone modifications and transcription factor interactions, essential to her investigations into G9a and PCAF functions. Xiuling has a strong foundation in virology, particularly involving endogenous retroviruses, which she integrates into neuroimmunology research. Her clinical role further equips her with real-world experience in sample handling, clinical diagnostics, and quality control procedures, bridging basic science with applied medicine. These capabilities have enabled her to produce high-quality research publications without extensive postdoctoral or institutional funding. Her technical self-sufficiency, combined with rigorous scientific thinking, positions her as a valuable contributor to the field of immunological research and molecular diagnostics.

Awards and Honors

As of now, Xiuling Wang has not received any formal academic awards, honors, or fellowships, nor has she been recognized through funded research grants such as those from the National Natural Science Foundation of China. Despite this, her scientific merit is evident through her publications in high-impact, peer-reviewed journals. Her work has been published in prestigious journals like Metabolism, Immunology & Cell Biology, Archives of Virology, and Brain, Behavior and Immunity, all of which require rigorous peer review and serve as a testament to her scholarly contributions. While institutional or national recognition remains an area for growth, her research output demonstrates academic independence, persistence, and relevance. She has navigated the competitive research landscape through individual effort and clinical integration, achieving visibility through her findings rather than through awards. This indicates that her contributions have been more organically driven by scientific inquiry than by external accolades. As her career continues, participating in professional societies, applying for national research funding, and engaging in collaborative projects could open opportunities for formal recognition. These steps would complement her existing academic foundation and further solidify her status in the biomedical research community.

Conclusion

Xiuling Wang exemplifies the qualities of a committed and capable biomedical researcher, blending clinical practice with rigorous academic investigation. With a doctoral degree in pathogenic biology and years of hands-on laboratory experience, she has carved a niche in understanding immune regulation and inflammatory pathways. Her work—particularly on macrophage polarization, endogenous retroviral proteins, and histone-modifying enzymes—has added valuable insight to the fields of immunology and neurobiology. While she has not yet led nationally funded projects or received major awards, her consistent publication record reflects both scientific competence and independence. She operates effectively in a clinical-academic environment, translating laboratory findings into contextually relevant insights. Her strengths lie in research depth, technical proficiency, and topic relevance. Future career development would benefit from expanded participation in funding applications, interdisciplinary collaborations, and recognition through academic awards or society memberships. Nonetheless, based on her publication impact and research quality, she stands as a strong candidate for the Best Researcher Award. Her potential for further contributions remains high, making her a valuable asset in the scientific exploration of immune mechanisms and inflammation-related diseases.

Publications Top Notes

  • Title: P300/CBP-associated factor (PCAF) attenuated M1 macrophage inflammatory responses possibly through KLF2 and KLF4

  • Journal: Immunology and Cell Biology

  • Year: 2021

  • Citations: 25

Veronika Bouskova | Molecular Biology | Best Researcher Award

Dr. Veronika Bouskova | Molecular Biology | Best Researcher Award

Young scientist from Biomedical Centre in Pilsen, Czech Republic.

Dr. Veronika Boušková (née Brynychová) is a distinguished Czech researcher in the field of molecular biology and pharmacogenomics, with a particular focus on breast cancer biology and genetic variability. Her career combines academic research, laboratory-based investigation, and mentoring of young scientists. With a Ph.D. from the Third Faculty of Medicine at Charles University and over a decade of experience at premier research institutions like the Biomedical Center of the Faculty of Medicine in Pilsen and the National Institute of Public Health in Prague, she has established herself as a leading expert in transcriptomic analysis, caspase signaling, and the clinical implications of genetic variants in cancer prognosis and treatment. Dr. Boušková has authored or co-authored numerous articles published in high-impact journals and holds an impressive h-index of 13. Her research is notable for its integrative approach, combining molecular, cellular, and genetic data to better understand cancer progression and therapy resistance. She is also actively involved in academic education and mentoring, guiding the next generation of scientists. Her ability to conduct interdisciplinary research and her contributions to clinical and translational oncology make her a strong candidate for recognition through research awards.

Professional Profile

Education

Dr. Boušková has pursued a rigorous and interdisciplinary educational path rooted in biological sciences. She earned her Bachelor’s degree in Biology from the Faculty of Science at Charles University in 2008, followed by a Master’s degree in Biology, which she completed in 2010 through a collaborative program involving the Department of Anthropology and Human Genetics and the Institute of Archaeology at the Academy of Sciences. Her education culminated in a Ph.D. in Molecular and Cell Biology, Genetics, and Virology from the Third Faculty of Medicine, Charles University, which she pursued from 2010 to 2018. Her doctoral studies provided her with a comprehensive understanding of molecular and cellular mechanisms involved in human diseases, with a particular emphasis on cancer genetics and apoptosis. This strong educational foundation, grounded in both human genetics and molecular medicine, has enabled her to bridge basic scientific research with clinical applications. Additionally, Dr. Boušková’s involvement in interdisciplinary and international study programs reflects her commitment to continuous academic and professional growth, and has enriched her scientific perspective with cultural and methodological diversity.

Professional Experience

Dr. Boušková’s professional journey reflects her long-standing commitment to biomedical research and her evolving expertise in oncology-related molecular genetics. Since 2013, she has served as a Junior Researcher at the Biomedical Center, Faculty of Medicine in Pilsen, Charles University, where she works in the Laboratory of Pharmacogenomics. Simultaneously, she has maintained a research position at the National Institute of Public Health in Prague since 2010. Her work across both institutions focuses on investigating genetic variability, apoptosis-related genes, and microRNA expression in cancer patients, especially those with breast carcinoma. Between August 2019 and January 2022, she was on maternity leave, after which she resumed her scientific endeavors. Dr. Boušková has also been actively involved in teaching since 2015, conducting practical courses in biochemical laboratory techniques at the Faculty of Science, Charles University. She has mentored and consulted graduate students, contributing to their academic development and research projects. Her dual roles in research and education reflect a well-rounded professional profile combining laboratory excellence, mentorship, and scientific publication. Her sustained engagement in public health-oriented molecular research illustrates her commitment to improving healthcare outcomes through advanced biomedical science.

Research Interests

Dr. Veronika Boušková’s research interests center on the molecular and genetic mechanisms underlying cancer development and progression, with a particular emphasis on breast carcinoma. Her work delves into the regulation of apoptosis, the role of caspases and their isoforms, transcriptomic alterations, and microRNA expression profiles in tumor cells. She is especially interested in the pharmacogenomic implications of genetic variability, including single nucleotide polymorphisms and gene expression regulation that influence cancer prognosis and therapy response. Her integrative research also covers transcript and protein expression of genes involved in cell cycle control, epithelial-mesenchymal transition, and multidrug resistance. Additionally, Dr. Boušková has explored the impact of epigenetic modifications and miRNA-mediated gene regulation in breast cancer subtypes. Her interdisciplinary approach, combining molecular biology, genetics, pharmacology, and bioinformatics, contributes to identifying potential therapeutic targets and predictive biomarkers. She is committed to translational research, bridging laboratory findings with clinical practice to enhance personalized medicine strategies in oncology. Her recent publications reflect ongoing investigations into breast cancer microenvironment signaling, resistance mechanisms, and molecular diagnostics, demonstrating her ability to stay at the forefront of contemporary cancer research.

Research Skills

Dr. Boušková possesses a broad and advanced skill set in molecular biology and cancer genomics, honed over years of hands-on laboratory experience. Her research skills include gene expression analysis using RT-qPCR, microarray profiling, RNA sequencing, and high-resolution melting analysis. She is proficient in DNA/RNA extraction, reverse transcription, genotyping, and bioinformatics tools for analyzing transcriptomic and genomic datasets. Dr. Boušková is also skilled in cell culture techniques, protein expression studies, and functional assays relevant to apoptosis and cell signaling pathways. Her expertise extends to microRNA analysis and the use of pathway prediction software for understanding gene regulation networks. Moreover, she is well-versed in data interpretation, manuscript preparation, and collaborative research processes, contributing meaningfully to multidisciplinary teams. Her methodological rigor is evident from her contributions to over 25 peer-reviewed publications, many in high-impact journals. Additionally, she has experience in research project planning, laboratory management, and supervising student projects. Her continuous engagement with modern experimental technologies and analytical software ensures her research remains current and impactful. Her technical proficiency, analytical mindset, and collaborative approach make her a valuable contributor to complex research initiatives.

Awards and Honors

Dr. Boušková’s career includes several academic and research achievements, reflecting her dedication to high-quality scientific work. Notably, she was the recipient of a research grant from the Charles University Grant Agency (GAUK) from 2013 to 2015 for her project on the significance of apoptotic caspases and their splice variants in breast carcinoma. The project was successfully evaluated with all objectives fulfilled, highlighting her ability to manage and complete competitive research funding initiatives. Furthermore, she was awarded an internship opportunity in May 2014 at the National Research Institute of Chinese Medicine, under Dr. Yune-Fang Ueng’s laboratory, indicating her proactive pursuit of international research exposure. While there are no listings of specific awards such as national medals or society fellowships, her consistent record of high-impact publications, a strong citation index, and an h-index of 13 represent substantial academic honors in themselves. Her mentoring of graduate students and teaching contributions also reflect recognition within academic circles. Dr. Boušková’s recognition comes primarily through peer-reviewed scientific contributions and successful grant acquisitions, both of which underscore her qualifications for further accolades like the Best Researcher Award.

Conclusion

Dr. Veronika Boušková exemplifies the qualities of a top-tier biomedical researcher with a career marked by academic excellence, impactful research, and active mentorship. Her scientific focus on breast cancer genomics, microRNA regulation, and pharmacogenomics addresses some of the most pressing challenges in oncology today. With a strong publication record, an h-index of 13, and sustained research activity at reputable institutions, she has demonstrated not only productivity but also relevance and innovation in her field. Her interdisciplinary education and global research exposure further enhance her ability to navigate complex scientific questions. While expanding her international collaborations and taking on larger leadership roles in research consortia could elevate her profile further, her current contributions already reflect a researcher of significant merit and potential. Her dual commitment to research and education positions her as an influential figure within both academic and clinical research landscapes. In light of her qualifications, Dr. Boušková is highly deserving of recognition through awards such as the Best Researcher Award, which would not only honor her achievements but also support her future research endeavors aimed at improving cancer diagnosis and treatment.

Publications Top Notes

  1. Integrative analysis of mRNA and miRNA expression profiles and somatic variants in oxysterol signaling in early-stage luminal breast cancer
    Authors: Petr Holý, Veronika Brynychová, Karolína Šeborová, Vojtěch Haničinec, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Pavel Souček, et al.
    Journal: Molecular Oncology
    Year: 2023
    Citations: 3
  2. Single Nucleotide Variants in KIF14 Gene May Have Prognostic Value in Breast Cancer
    Authors: Ivona Krus, Veronika Brynychová, Viktor Hlaváč, Radka Václavíková, Maria Kováčová, Renata Koževnikovová, Kateřina Kopečková, Jannis Tornikidis, David Vrána, Jiří Gatěk, Pavel Souček
    Journal: Molecular Diagnosis and Therapy
    Year: 2022
    Citations: 2