Guoguo Jin | Medicine and Dentistry | Best Researcher Award

Assoc. Prof. Dr. Guoguo Jin | Medicine and Dentistry | Best Researcher Award

Deputy Director from Key Laboratory of Chronic Disease Health Management of Henan Province, China

Dr. Guoguo Jin is an accomplished biomedical researcher specializing in the chemical prevention of tumors. With a strong foundation in pathology and bioengineering, she has steadily developed a research career that bridges cancer biology and cardiovascular complications arising from oncological treatments. Her work delves into the molecular mechanisms underlying tumorigenesis, cardiotoxicity from chemotherapeutic agents, and the identification of therapeutic targets for various cancers, particularly esophageal, gastric, and colon carcinomas. Dr. Jin currently serves as the Deputy Director of both the Key Laboratory of Chronic Disease Health Management and the Department of Scientific Research and Discipline Construction at Fuwai Central China Cardiovascular Hospital. She has led several national and provincial-level research projects and has published extensively in top-tier journals. Her research contributions are complemented by multiple patents aimed at mitigating drug-induced cardiotoxicity. Recognized for her leadership and scientific acumen, she has received accolades such as the Young and Middle-aged Academic Leader title from the Health Commission of Henan Province. Overall, Dr. Jin’s work represents a compelling blend of scientific rigor, clinical relevance, and translational potential. Her continued efforts are likely to yield significant advancements in cancer therapy and patient care.

Professional Profile

Education

Dr. Guoguo Jin began her academic journey in bioengineering, earning her Master’s degree from the School of Bioengineering at Zhengzhou University in July 2011. This foundational training equipped her with critical insights into biomedical sciences and experimental techniques. She then pursued her doctoral studies in pathology and pathophysiology at the Basic Medical College of Zhengzhou University, receiving her Ph.D. in July 2017. During her doctoral program, she was selected for an international joint training opportunity and spent two years (2015–2017) at the prestigious Hormel Institute, University of Minnesota. There, she conducted in-depth research into the signal transduction pathways related to tumorigenesis and its prevention. Her time abroad not only enriched her technical competencies but also exposed her to cutting-edge methodologies in cancer biology. This combination of local and international academic training has laid a solid foundation for her ongoing research into tumor mechanisms and therapeutic strategies. Dr. Jin’s educational background reflects a trajectory of consistent academic excellence and scientific curiosity, establishing her as a capable and knowledgeable researcher in the fields of oncology and pathology.

Professional Experience

Dr. Guoguo Jin currently holds dual leadership roles at Fuwai Central China Cardiovascular Hospital, where she serves as Deputy Director of both the Key Laboratory of Chronic Disease Health Management of Henan Province and the Department of Scientific Research and Discipline Construction. Her professional responsibilities primarily involve overseeing tumor-related research and institutional academic development. Earlier in her career, she gained international experience at the Hormel Institute, University of Minnesota, where she focused on cancer signal transduction pathways. This exposure to high-impact research environments significantly influenced her approach to scientific inquiry. Throughout her career, Dr. Jin has successfully led multiple research projects funded at both national and provincial levels. These projects explore the molecular mechanisms of drug-induced cardiotoxicity, tumor progression, and the discovery of small-molecule inhibitors. Her clinical and translational research activities are closely integrated with her hospital’s goals, enhancing the relevance and impact of her findings. With a strong blend of laboratory management, project leadership, and interdepartmental coordination, Dr. Jin’s professional journey reflects her growth from a bench scientist to an influential figure in medical research administration. Her dual roles in scientific research and academic governance enable her to contribute meaningfully to both science and institutional progress.

Research Interest

Dr. Guoguo Jin’s primary research interest lies in the chemical prevention of tumors, with a focus on uncovering the molecular mechanisms that drive carcinogenesis and treatment-related complications. She is particularly interested in the pathways that regulate tumor initiation and progression in gastrointestinal cancers such as esophageal, gastric, and colon cancer. A significant portion of her work also explores the cardiotoxic effects of chemotherapeutic agents like osimertinib and doxorubicin, aiming to develop strategies to mitigate these adverse outcomes. Her recent studies have investigated the roles of signaling molecules such as WNK1, hnRNPU, AHCY-LDHA, and ZIP8 in cancer development and progression. Dr. Jin is also deeply involved in the identification and evaluation of small-molecule inhibitors and natural compounds like α-mangostin and curcumin for their anti-tumor efficacy. Her research bridges basic science and clinical application, positioning her work at the forefront of translational oncology. Through the development of targeted therapies and predictive biomarkers, she aims to improve both treatment outcomes and quality of life for cancer patients. This integrated focus on cancer biology and cardiotoxicity underlines her commitment to advancing personalized medicine in oncology.

Research Skills

Dr. Guoguo Jin possesses a wide array of research skills, especially in molecular and cellular biology techniques relevant to oncology. She is proficient in signal transduction analysis, gene expression profiling, histone modification studies, and functional validation of oncogenes and tumor suppressors. Her expertise extends to the use of in vitro and in vivo cancer models to study the efficacy and mechanisms of chemopreventive agents. She has demonstrated a high level of competence in utilizing molecular techniques such as Western blotting, qRT-PCR, immunohistochemistry, and chromatin immunoprecipitation assays. Her postdoctoral training at the Hormel Institute allowed her to master advanced techniques for dissecting signaling pathways in cancer. In addition to experimental skills, Dr. Jin has a solid foundation in project design, grant writing, and data analysis. She is also skilled in translating laboratory findings into potential therapeutic applications, as demonstrated by her patents. Moreover, her ability to manage multidisciplinary teams and coordinate with clinical departments enhances the practical relevance of her research. These competencies enable her to effectively lead complex biomedical projects from conceptualization to execution and dissemination.

Awards and Honors

Dr. Guoguo Jin has received multiple awards and honors that underscore her impact and promise in the field of medical research. In February 2024, she was selected as a Young and Middle-aged Academic Leader in Health and Wellness by the Health Commission of Henan Province, a recognition of her leadership in translational cancer research. Later that year, she was awarded a position in the National-Level Talent Cultivation Project for First-Class Discipline in Clinical Medicine at Zhengzhou University. Dr. Jin has also secured several competitive research grants, including the National Natural Science Foundation Youth Project, the Science and Technology Tackling Project by the Department of Science and Technology of Henan Province, and the Outstanding Young Talent Training Program for Health and Technology Innovation. Her innovative research on cancer prevention and cardiotoxicity has led to two patents, further highlighting her commitment to developing clinically relevant solutions. These accolades reflect not only her scientific excellence but also her dedication to advancing health outcomes through rigorous and applied research. The consistent support from national and provincial agencies illustrates her status as a leading figure in her domain.

Conclusion

Dr. Guoguo Jin exemplifies the qualities of a leading researcher with her focused expertise in chemical tumor prevention and translational oncology. Her well-rounded background—from robust academic training to leadership in high-impact research—positions her as a valuable contributor to both the scientific community and clinical practice. Her studies on molecular mechanisms of cancer progression and cardiotoxicity have not only expanded academic understanding but have also offered practical pathways for improving patient outcomes. Through national and provincial grants, influential publications, and patented innovations, she continues to push the boundaries of cancer therapy and prevention. While her research is already making a meaningful impact, future expansion into international collaborations and clinical trials could further elevate her contributions. Overall, Dr. Jin’s career is marked by scientific rigor, visionary leadership, and a commitment to translating research into real-world solutions. She is a highly deserving candidate for recognition through honors such as the Best Researcher Award and is likely to make even greater strides in cancer research in the years to come.

Publications Top Notes

  1. Title: STIP1 drives metabolic reprogramming in esophageal squamous cell carcinoma via AHCY-LDHA axis
    Authors: Jin G, Song Y, Yan M, Fang S, Shao Y, Zhao K, Liu M, Guo Q, Jia X, Zhang C, Wang Z, Liu K, Li X, Zhao S, Guo Z, Dong Z
    Year: 2025

  2. Title: hnRNPU-mediated pathogenic alternative splicing drives gastric cancer progression
    Authors: Jin G, Song Y, Fang S, Yan M, Yang Z, Shao Y, Zhao K, Liu M, Wang Z, Guo Z, Dong Z
    Year: 2025

  3. Title: ZIP8 modulates ferroptosis to drive esophageal carcinoma progression
    Authors: Yang Z, Zhao K, Li X, Yanzhang R, Zhang H, Yu Y, Yan M, Fang S, Li T, Li H, Chu X, Han S, Zhang Z, Teng J, Jin G, Guo Z
    Year: 2025

  4. Title: Discovery of a novel dual-target inhibitor against RSK1 and MSK2 to suppress growth of human colon cancer
    Authors: Jin G, Yan M, Liu K, Yao K, Chen H, Zhang C, Yi Y, Reddy K, Gorja DR, Laster KV, Guo Z, Dong Z
    Year: 2020

  5. Title: Ginger extract inhibits c-MET activation and suppresses osteosarcoma in vitro and in vivo
    Authors: Yanzhang R, Yan M, Yang Z, Zhang H, Yu Y, Li X, Shen R, Chu X, Han S, Zhang Z, Teng J, Li H, Li T, Jin G, Guo Z
    Year: 2025

  6. Title: PDK1-mediated phosphorylation of USP5 modulates NF-κB signalling to enhance osteosarcoma growth
    Authors: Yang Z, Yu Z, Teng J, Yanzhang R, Yu Y, Zhang H, Jin G, Wang F
    Year: 2025

  7. Title: Precision therapy for cancer prevention by targeting carcinogenesis
    Authors: Jin G, Liu K, Guo Z, Dong Z*
    Year: 2024

  8. Title: Decrypting the Molecular Mechanistic Pathways Delineating the Chemotherapeutic Potential of Ruthenium-Phloretin Complex in Colon Carcinoma Correlated with the Oxidative Status and Increased Apoptotic Events
    Authors: Jin G, Zhao Z, Chakraborty T, et al.
    Year: 2020

  9. Title: Aurora B kinase as a novel molecular target for inhibition the growth of osteosarcoma
    Authors: Zhao Z, Jin G, Yao K, Liu K, Liu F, Chen H, Wang K, Gorja DR, Reddy K, Bode A.M., Guo Z, Dong Z
    Year: 2019

  10. Title: Resveratrol suppresses colon cancer growth by targeting the AKT/STAT3 signaling pathway
    Authors: Li D, Wang G, Jin G, Yao K, Zhao Z, Bie L, Guo Y, Li N, Deng W, Chen X, Chen B, Liu Y, Luo S, Guo Z
    Year: 2019

Kumiko Tajima | Medicine and Dentistry | Women Researcher Award

Dr. Kumiko Tajima | Medicine and Dentistry | Women Researcher Award

Manager from Gunma Central Hospital, Japan

Kumiko Tajima is a highly qualified medical professional with extensive experience in internal medicine and diabetes care. She graduated from Gunma University School of Medicine in 1992 and completed graduate studies at Gunma University Graduate School in 1999. With over two decades of clinical practice, she has served at several prominent medical institutions in Japan, including Gunma University School of Medicine, National Takasaki Hospital, and Gunma Prefectural Cardiovascular Center. Since 2014, she has been practicing at Gunma Central Hospital. Kumiko is recognized as a certified physician by the Japanese Society of Internal Medicine and specializes in general internal medicine and diabetes management. Her career is marked by a strong commitment to patient care, education, and specialized training, including roles as an instructor for medical training programs. She also serves vulnerable populations as a designated physician for disabilities and intractable diseases. While her clinical expertise is well documented, her research involvement is not explicitly detailed in the information available, suggesting a potential focus on clinical practice and medical education over research output. Nevertheless, her professional credentials and dedication to healthcare highlight her as a respected figure in the medical community.

Professional Profile

Education

Kumiko Tajima completed her formal education at Gunma University, one of Japan’s reputable institutions. She graduated from the Gunma University School of Medicine in 1992, where she acquired the foundational knowledge and clinical skills required to pursue a medical career. Following her medical degree, she advanced her expertise by completing graduate studies at Gunma University Graduate School in 1999. This postgraduate education likely included clinical research or advanced medical training, equipping her with enhanced knowledge in medical sciences. Her educational background provided a strong base for her subsequent clinical work and certifications in various medical specialties. Being an alumna of the same university for both undergraduate and graduate studies suggests continuity and depth in her academic preparation. Her education set the stage for her later roles in internal medicine, diabetes specialization, and her involvement in training programs. The rigorous training at Gunma University, known for its emphasis on both research and clinical practice, has likely influenced her professional trajectory, balancing patient care with medical education.

Professional Experience

Kumiko Tajima has accumulated significant clinical experience working in multiple prestigious medical institutions across Japan. Early in her career, she worked at Gunma University School of Medicine, which provided her with exposure to academic medicine and clinical research environments. She also served at National Takasaki Hospital, Tatebayashi Kosei Hospital, and Gunma Prefectural Cardiovascular Center, gaining diverse experience in patient care across various specialties and healthcare settings. Since 2014, she has been a key medical professional at Gunma Central Hospital, where she continues to provide specialized care in internal medicine and diabetes management. Throughout her career, she has been recognized for her expertise by multiple Japanese medical societies, reflected in her qualifications as a certified physician and specialist. She holds important roles such as a training instructor for diabetes care and general medical training, indicating her leadership in mentoring younger physicians. Additionally, her designation as a physician under the Welfare Act for the Physically Disabled and for intractable diseases highlights her involvement in public health and complex patient populations. Her extensive clinical roles demonstrate a strong foundation in both patient care and medical education.

Research Interests

While explicit details about Kumiko Tajima’s research interests are not provided in the information available, it is reasonable to infer that her research focus aligns closely with her clinical specialties—internal medicine and diabetes. Given her certifications and instructor roles within the Japan Diabetes Society, she likely engages with research related to diabetes management, treatment outcomes, and possibly public health aspects of chronic diseases. Her designation as a physician responsible for intractable diseases suggests potential interest in complex, difficult-to-treat conditions that may require innovative clinical approaches or translational research. Moreover, her role in general medical training indicates a probable interest in medical education research or clinical practice improvement. Without specific publications or ongoing research projects mentioned, her primary contributions may be in applying clinical knowledge to patient care and educating the next generation of physicians. If involved in research, it may focus on improving clinical protocols, diabetes education, or interdisciplinary care for chronic disease patients. Confirmation of such interests would strengthen her profile as a clinician-researcher.

Research Skills

Kumiko Tajima’s documented expertise suggests strong clinical skills particularly in internal medicine, diabetes care, and training future medical professionals. As a certified specialist and instructor in diabetes, she likely possesses advanced skills in managing complex cases, interpreting clinical data, and applying evidence-based medicine. Her role as an industrial physician and designated physician for the disabled reflects proficiency in occupational health and specialized patient management. Although there is no explicit mention of laboratory or bench research skills, her graduate education and clinical roles imply familiarity with clinical research methodologies, patient data analysis, and possibly clinical trial participation. Her instructional roles also suggest capabilities in curriculum development, clinical supervision, and medical education, which are important research-adjacent skills. If involved in research activities, these skills would be foundational for clinical studies, epidemiological research, or healthcare quality improvement projects. To enhance her research profile, further skills in scientific writing, grant applications, and collaboration in research networks would be beneficial.

Awards and Honors

The provided information does not list any specific awards or honors received by Kumiko Tajima. However, her qualifications as a certified physician by reputable Japanese medical societies, and her appointment as a specially appointed instructor for general medical training, indicate professional recognition within the medical community. These certifications and instructor roles can be seen as professional honors reflecting her expertise and dedication to clinical excellence and education. Additionally, her designation as a physician for intractable diseases and disabilities suggests recognition of her specialized skills and trust placed in her by public health authorities. While no formal awards are cited, her career achievements and appointments demonstrate a high level of respect and acknowledgment from her peers and regulatory bodies. Should she have received awards related to clinical innovation, research contributions, or teaching excellence, including these would enhance her profile for awards specifically focused on research.

Conclusion

Kumiko Tajima is an experienced and highly qualified medical professional with strong credentials in internal medicine and diabetes care. Her clinical expertise, long-standing service in multiple hospitals, and roles in medical training and specialized care demonstrate her dedication to both patient health and medical education. While she holds numerous certifications and leadership roles within professional medical societies, her profile lacks explicit information on research outputs, publications, or scientific contributions. For a Women Researcher Award focused on research excellence, evidence of active research involvement or scholarly achievements would be necessary to strengthen her candidacy. Nevertheless, her commitment to specialized clinical care, training, and vulnerable patient populations underscores her valuable role in the healthcare system. If supplemented by further details on her research activities, Kumiko Tajima could be a strong candidate. Currently, her profile is more aligned with clinical leadership and education, rather than research-centric recognition.

Publications Top Notes

  1. A case of SHORT syndrome with a novel genetic mutation diagnosed 19 years after the onset of diabetes

    • Authors: Kumiko Tajima, Yushi Hirota, Tomofumi Takayoshi, Wataru Ogawa

    • Year: 2025

  2. Medical Mystery: Abnormal Abdominal Radiograph — The Answer

    • Authors: Masahiko Kurabayashi, Kumiko Tajima

    • Year: 2007

  3. Medical Mystery — Abnormal Abdominal Radiograph

    • Authors: Kumiko Tajima, Masahiko Kurabayashi

    • Year: 2006