Tag: young medicine award

Shaobing Hua | Medicine and Dentistry | Best Innovation Award

Published on by Shen Awards

Prof. Dr. Shaobing Hua | Medicine and Dentistry | Best Innovation Award

Hangzhou Dalton Biosciences Ltd | China

Prof. Dr. Shaobing Hua is a distinguished biomedical scientist and innovator whose career spans more than three decades of impactful contributions to molecular biology, therapeutic antibody discovery, and advanced diagnostic technologies. Trained as a molecular biologist with postdoctoral experience at leading U.S. research institutions, he has played a pivotal role in translating fundamental discoveries into clinically deployable solutions. His early work advanced the understanding of signal transduction, proteasome regulation, and gene expression in protozoan parasites, laying the foundation for subsequent research in therapeutic antibody platforms, which led to multiple U.S. and international patents for novel humanized antibodies and high-throughput screening methods. Prof. Hua is widely recognized for developing next-generation hybrid capture technologies and innovative HPV testing platforms that have transformed cervical cancer screening, particularly in resource-limited settings. Under his scientific leadership, DALTON BioSciences has introduced a suite of diagnostic products for cervical cancer, endometrial carcinoma, pre-eclampsia, and vaginitis, contributing to the health of nearly 30 million women. His portfolio includes over 30 peer-reviewed publications in journals such as Journal of Biological Chemistry, Clinical Cancer Research, Protein Science, and Oncogene, and several dozens of patents granted in the United States, China, and the PCT system. His work has been cited widely by researchers across molecular diagnostics, oncology, and immunotechnology. Throughout his career, Prof. Hua has collaborated extensively with major clinical institutions, including leading hospitals affiliated with Zhejiang University, Peking University, the Chinese Academy of Medical Sciences, and several provincial oncology centers. He has served in key roles in national research programs, including China’s 863 Program, national key research plans, and major public health initiatives focused on cervical cancer elimination. His contributions have significantly advanced women’s health diagnostics, strengthened public health infrastructures, and accelerated the global adoption of innovative molecular screening technologies. Prof. Hua’s research, leadership, and translational impact continue to shape the future of precision diagnostics and global health innovation.

Profile: ORCID

Featured Publications

Liu, S., Han, B., Jin, D. Q., Li, L. W., Ge, T. T., Shou, Y. J., Ye, J. M., Zhang, L., & Hua, S. B. (2025). Design and development of a target amplification-free microfluidic platform for multiplex nucleic acids detection: A new generation of hybrid capture immunoassay. Journal of Medical Virology.

Ding, L., Lin, Y. H., Azam, M., Sheridan, J., Wei, S., Gupta, G., Singh, R. K., Pauling, M. H., Chu, A., Tran, A., Yu, N., Hu, J., Wang, W., Long, H., Xiang, D., Zhu, L., & Hua, S. B. (2010). Generation of high-affinity fully human anti-human interleukin-8 antibodies from its cDNA by two-hybrid screening and affinity maturation in yeast. Protein Science, 19, 1957–1966.

Vaday, G. G., Hua, S. B., Peehl, D. M., Pauling, M. H., Lin, Y. H., Zhu, L., Lawrence, D. M., Foda, H. D., & Zucker, S. (2004). CXCR4 and CXCL12 (SDF-1) in prostate cancer: Inhibitory effects of human single-chain Fv antibodies. Clinical Cancer Research, 10, 5630–5639.

Xia, C., Ma, W., Wang, F., Hua, S. B., & Liu, M. (2001). Identification of a prostate-specific G-protein coupled receptor in prostate cancer. Oncogene, 20, 5903–5907.

Xia, C., Bao, Z., Tabassam, F., Ma, W., Qiu, M., Hua, S. B., & Liu, M. (2000). GCIP, a novel human Grap2 and Cyclin D interacting protein, regulates E2F-mediated transcriptional activity. Journal of Biological Chemistry, 275, 20942–20948.

Ricardo Osorio | Medicine and Dentistry | Best Researcher Award

Published on by Shen Awards

Dr. Ricardo Osorio | Medicine and Dentistry | Best Researcher Award

NYU Grossman School of Medicine, United States

Dr. Ricardo Osorio is a distinguished neuropsychiatrist and researcher specializing in the intersection of sleep, aging, and neurodegenerative disorders, particularly Alzheimer’s disease. He earned his M.D. from Universidad Autónoma de Madrid (Spain) in 2001, followed by multiple master’s degrees in Psychotherapy, Neuroscience, and Neuropsychology from Universidad Comillas and Universidad Complutense, Madrid, with a focus on executive function and cognitive aging. His clinical training includes residencies in psychiatry at 12 de Octubre Hospital, Madrid, internships in neurology at McGill University, Montreal, and neuropsychiatry at the Institute of Neurology, London, as well as postdoctoral neuroscience training at NYU Langone Health. Dr. Osorio’s professional career encompasses roles as attending psychiatrist in several Spanish hospitals, research scientist at Alzheimer’s Project Research Unit (CIEN Foundation) in Madrid, and progressive academic appointments at NYU School of Medicine and the Healthy Brain Aging and Sleep Center, where he is now a tenured associate professor. His research interests focus on sleep disorders as risk factors for neurodegeneration, slow-wave sleep and sleep spindle physiology, memory consolidation, and advanced neuroimaging techniques including PET imaging of glucose metabolism, amyloid, and tau in normal aging, cognitive decline, and Alzheimer’s disease. He possesses expertise in clinical psychiatry, cognitive assessment, neuroimaging analysis, sleep research methodologies, and interdisciplinary translational research. Dr. Osorio has received numerous awards and honors, including international fellowships, the Spanish National Psychiatry Residents Research Award, the Anne Elizabeth Suratt Young Investigator Award, and departmental mentorship recognitions. He has authored 130 publications, accumulated 9,893 citations, and holds an h-index of 44, reflecting his impactful contributions to science and clinical practice. Dr. Osorio’s work bridges neuroscience and clinical application, advancing understanding of cognitive aging, informing early detection strategies for Alzheimer’s disease, and contributing to the development of interventions that benefit patients and society at large, marking him as a leading figure in neuropsychiatric research and aging studies.

Profiles: Scopus | ORCID

Featured Publications

  1. Bernard, M. A., Boutajangout, A., Debure, L., Ahmed, W., Briggs, A. Q., Boza-Calvo, C., Vedvyas, A., Marsh, K., Bubu, O. M., Osorio, R. S., et al. (2024, July 10). The relationship between anxiety and levels of Alzheimer’s disease plasma biomarkers. Preprint.

  2. Iosifescu, D. V., Song, X., Gersten, M. B., Adib, A., Cho, Y., Collins, K. M., Yates, K. F., Hurtado-Puerto, A. M., McEachern, K. M., Osorio, R. S., et al. (2023, July 13). Protocol report on the transcranial photobiomodulation for Alzheimer’s disease (TRAP-AD) study. Healthcare, 11(14), 2017.

  3. Parasoglou, P., Osorio, R. S., Khegai, O., Kovbasyuk, Z., Miller, M., Ho, A., Dehkharghani, S., Wisniewski, T., Convit, A., Mosconi, L., et al. (2022, December). Phosphorus metabolism in the brain of cognitively normal midlife individuals at risk for Alzheimer’s disease. Neuroimage: Reports, 2, 100121.

  4. Lal, C., Ayappa, I., Ayas, N., Beaudin, A. E., Hoyos, C., Kushida, C. A., Kaminska, M., Mullins, A., Naismith, S. L., Osorio, R. S., et al. (2022, August). The link between obstructive sleep apnea and neurocognitive impairment: An official American Thoracic Society workshop report. Annals of the American Thoracic Society, 19(8), 1250–1267.

  5. Teipel, S., Bruno, D., Plaska, C. R., Heslegrave, A., Ramos-Cejudo, J., Osorio, R. S., Zetterberg, H., Blennow, K., & Pomara, N. (2021, October). Association of CSF sTREM2, a marker of microglia activation, with cholinergic basal forebrain volume in major depressive disorder. Journal of Affective Disorders, 295, 1017–1025.

Dr. Ricardo Osorio’s work advances the understanding of sleep and neurodegenerative disorders, particularly Alzheimer’s disease, by identifying early risk factors and therapeutic targets. His research bridges neuroscience and clinical practice, improving strategies for diagnosis, prevention, and intervention, thereby benefiting patients, healthcare systems, and society globally.

Seo-Eun Choi | Medicine and Dentistry | Best Researcher Award

Published on by Shen Awards

Dr. Seo-Eun Choi | Medicine and Dentistry | Best Researcher Award

University of Washington, United States

Dr. Seo-Eun Choi is a distinguished Senior Research Scientist at the University of Washington, specializing in statistical applications in biomedical research, particularly Alzheimer’s disease and cognitive studies. She holds a Ph.D. in Statistics from Florida State University, an M.S. in Statistics from the University of Michigan – Ann Arbor, and a B.S. in Statistics with a minor in Computer Science from Ewha Womans University, South Korea. Over her career, Dr. Choi has developed deep expertise in Bayesian modeling, model selection, categorical and multivariate data analysis, spatio-temporal modeling, psychometrics, and neuroimaging data analysis. She has led and contributed to numerous international and interdisciplinary research projects, producing a strong publication record of 96 documents with 728 citations and an h-index of 12, highlighting her influence in both statistical methodology and clinical applications. Her research skills include advanced statistical computing, data visualization, and application of complex statistical models to large-scale neuroimaging and clinical datasets. Dr. Choi is an active member of the Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) and the American Statistical Association (ASA), reflecting her engagement with the broader scientific community and commitment to advancing collaborative research initiatives. Her contributions have been recognized through multiple awards and honors for excellence in statistical research, interdisciplinary collaboration, and mentorship, demonstrating her leadership and impact on the field. Looking forward, Dr. Choi’s work has significant potential to advance high-impact publications in Q1 journals, expand global collaborations, and provide mentorship to emerging researchers, thereby influencing both methodological innovation and practical applications in neurodegenerative disease research. Her combination of expertise, experience, and dedication makes her an exemplary candidate for recognition, reflecting outstanding contributions to science, research leadership, and societal impact in the field of biostatistics and neuroscience.

Profile: Google Scholar

Featured Publications

  1. Jutten, R. J., Grandoit, E., Foldi, N. S., Sikkes, S. A. M., Jones, R. N., Choi, S. E., … et al. (2020). Lower practice effects as a marker of cognitive performance and dementia risk: A literature review. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 12(1), 1–12.

  2. Mukherjee, S., Mez, J., Trittschuh, E. H., Saykin, A. J., Gibbons, L. E., Fardo, D. W., … et al. (2020). Genetic data and cognitively defined late-onset Alzheimer’s disease subgroups. Molecular Psychiatry, 25(11), 2942–2951.

  3. Choi, S. E., Mukherjee, S., Gibbons, L. E., Sanders, R. E., Jones, R. N., Tommet, D., … et al. (2020). Development and validation of language and visuospatial composite scores in ADNI. Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 6(1), e12024.

  4. Eissman, J. M., Dumitrescu, L., Mahoney, E. R., Smith, A. N., Mukherjee, S., Lee, M. L., … et al. (2022). Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease. Brain, 145(7), 2541–2554.

  5. Mukherjee, S., Choi, S. E., Lee, M. L., Scollard, P., Trittschuh, E. H., Mez, J., … et al. (2020). Cognitive domain harmonization and co-calibration in studies of older adults. Neuropsychology, 37(4), 409–423.