Dr. Veronika Boušková (née Brynychová) is a distinguished Czech researcher in the field of molecular biology and pharmacogenomics, with a particular focus on breast cancer biology and genetic variability. Her career combines academic research, laboratory-based investigation, and mentoring of young scientists. With a Ph.D. from the Third Faculty of Medicine at Charles University and over a decade of experience at premier research institutions like the Biomedical Center of the Faculty of Medicine in Pilsen and the National Institute of Public Health in Prague, she has established herself as a leading expert in transcriptomic analysis, caspase signaling, and the clinical implications of genetic variants in cancer prognosis and treatment. Dr. Boušková has authored or co-authored numerous articles published in high-impact journals and holds an impressive h-index of 13. Her research is notable for its integrative approach, combining molecular, cellular, and genetic data to better understand cancer progression and therapy resistance. She is also actively involved in academic education and mentoring, guiding the next generation of scientists. Her ability to conduct interdisciplinary research and her contributions to clinical and translational oncology make her a strong candidate for recognition through research awards.
Professional Profile
Education
Dr. Boušková has pursued a rigorous and interdisciplinary educational path rooted in biological sciences. She earned her Bachelor’s degree in Biology from the Faculty of Science at Charles University in 2008, followed by a Master’s degree in Biology, which she completed in 2010 through a collaborative program involving the Department of Anthropology and Human Genetics and the Institute of Archaeology at the Academy of Sciences. Her education culminated in a Ph.D. in Molecular and Cell Biology, Genetics, and Virology from the Third Faculty of Medicine, Charles University, which she pursued from 2010 to 2018. Her doctoral studies provided her with a comprehensive understanding of molecular and cellular mechanisms involved in human diseases, with a particular emphasis on cancer genetics and apoptosis. This strong educational foundation, grounded in both human genetics and molecular medicine, has enabled her to bridge basic scientific research with clinical applications. Additionally, Dr. Boušková’s involvement in interdisciplinary and international study programs reflects her commitment to continuous academic and professional growth, and has enriched her scientific perspective with cultural and methodological diversity.
Professional Experience
Dr. Boušková’s professional journey reflects her long-standing commitment to biomedical research and her evolving expertise in oncology-related molecular genetics. Since 2013, she has served as a Junior Researcher at the Biomedical Center, Faculty of Medicine in Pilsen, Charles University, where she works in the Laboratory of Pharmacogenomics. Simultaneously, she has maintained a research position at the National Institute of Public Health in Prague since 2010. Her work across both institutions focuses on investigating genetic variability, apoptosis-related genes, and microRNA expression in cancer patients, especially those with breast carcinoma. Between August 2019 and January 2022, she was on maternity leave, after which she resumed her scientific endeavors. Dr. Boušková has also been actively involved in teaching since 2015, conducting practical courses in biochemical laboratory techniques at the Faculty of Science, Charles University. She has mentored and consulted graduate students, contributing to their academic development and research projects. Her dual roles in research and education reflect a well-rounded professional profile combining laboratory excellence, mentorship, and scientific publication. Her sustained engagement in public health-oriented molecular research illustrates her commitment to improving healthcare outcomes through advanced biomedical science.
Research Interests
Dr. Veronika Boušková’s research interests center on the molecular and genetic mechanisms underlying cancer development and progression, with a particular emphasis on breast carcinoma. Her work delves into the regulation of apoptosis, the role of caspases and their isoforms, transcriptomic alterations, and microRNA expression profiles in tumor cells. She is especially interested in the pharmacogenomic implications of genetic variability, including single nucleotide polymorphisms and gene expression regulation that influence cancer prognosis and therapy response. Her integrative research also covers transcript and protein expression of genes involved in cell cycle control, epithelial-mesenchymal transition, and multidrug resistance. Additionally, Dr. Boušková has explored the impact of epigenetic modifications and miRNA-mediated gene regulation in breast cancer subtypes. Her interdisciplinary approach, combining molecular biology, genetics, pharmacology, and bioinformatics, contributes to identifying potential therapeutic targets and predictive biomarkers. She is committed to translational research, bridging laboratory findings with clinical practice to enhance personalized medicine strategies in oncology. Her recent publications reflect ongoing investigations into breast cancer microenvironment signaling, resistance mechanisms, and molecular diagnostics, demonstrating her ability to stay at the forefront of contemporary cancer research.
Research Skills
Dr. Boušková possesses a broad and advanced skill set in molecular biology and cancer genomics, honed over years of hands-on laboratory experience. Her research skills include gene expression analysis using RT-qPCR, microarray profiling, RNA sequencing, and high-resolution melting analysis. She is proficient in DNA/RNA extraction, reverse transcription, genotyping, and bioinformatics tools for analyzing transcriptomic and genomic datasets. Dr. Boušková is also skilled in cell culture techniques, protein expression studies, and functional assays relevant to apoptosis and cell signaling pathways. Her expertise extends to microRNA analysis and the use of pathway prediction software for understanding gene regulation networks. Moreover, she is well-versed in data interpretation, manuscript preparation, and collaborative research processes, contributing meaningfully to multidisciplinary teams. Her methodological rigor is evident from her contributions to over 25 peer-reviewed publications, many in high-impact journals. Additionally, she has experience in research project planning, laboratory management, and supervising student projects. Her continuous engagement with modern experimental technologies and analytical software ensures her research remains current and impactful. Her technical proficiency, analytical mindset, and collaborative approach make her a valuable contributor to complex research initiatives.
Awards and Honors
Dr. Boušková’s career includes several academic and research achievements, reflecting her dedication to high-quality scientific work. Notably, she was the recipient of a research grant from the Charles University Grant Agency (GAUK) from 2013 to 2015 for her project on the significance of apoptotic caspases and their splice variants in breast carcinoma. The project was successfully evaluated with all objectives fulfilled, highlighting her ability to manage and complete competitive research funding initiatives. Furthermore, she was awarded an internship opportunity in May 2014 at the National Research Institute of Chinese Medicine, under Dr. Yune-Fang Ueng’s laboratory, indicating her proactive pursuit of international research exposure. While there are no listings of specific awards such as national medals or society fellowships, her consistent record of high-impact publications, a strong citation index, and an h-index of 13 represent substantial academic honors in themselves. Her mentoring of graduate students and teaching contributions also reflect recognition within academic circles. Dr. Boušková’s recognition comes primarily through peer-reviewed scientific contributions and successful grant acquisitions, both of which underscore her qualifications for further accolades like the Best Researcher Award.
Conclusion
Dr. Veronika Boušková exemplifies the qualities of a top-tier biomedical researcher with a career marked by academic excellence, impactful research, and active mentorship. Her scientific focus on breast cancer genomics, microRNA regulation, and pharmacogenomics addresses some of the most pressing challenges in oncology today. With a strong publication record, an h-index of 13, and sustained research activity at reputable institutions, she has demonstrated not only productivity but also relevance and innovation in her field. Her interdisciplinary education and global research exposure further enhance her ability to navigate complex scientific questions. While expanding her international collaborations and taking on larger leadership roles in research consortia could elevate her profile further, her current contributions already reflect a researcher of significant merit and potential. Her dual commitment to research and education positions her as an influential figure within both academic and clinical research landscapes. In light of her qualifications, Dr. Boušková is highly deserving of recognition through awards such as the Best Researcher Award, which would not only honor her achievements but also support her future research endeavors aimed at improving cancer diagnosis and treatment.
Publications Top Notes
- Integrative analysis of mRNA and miRNA expression profiles and somatic variants in oxysterol signaling in early-stage luminal breast cancer
Authors: Petr Holý, Veronika Brynychová, Karolína Šeborová, Vojtěch Haničinec, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Pavel Souček, et al.
Journal: Molecular Oncology
Year: 2023
Citations: 3
- Single Nucleotide Variants in KIF14 Gene May Have Prognostic Value in Breast Cancer
Authors: Ivona Krus, Veronika Brynychová, Viktor Hlaváč, Radka Václavíková, Maria Kováčová, Renata Koževnikovová, Kateřina Kopečková, Jannis Tornikidis, David Vrána, Jiří Gatěk, Pavel Souček
Journal: Molecular Diagnosis and Therapy
Year: 2022
Citations: 2