Xiumin Wang | Molecular Biology | Women Researcher Award

Prof. Dr. Xiumin Wang | Molecular Biology | Women Researcher Award

Researcher at Feed Research Institute, Chinese Academy of Agricultural Sciences, China

Dr. Wang Xiumin is a distinguished researcher currently serving at the Institute of Feed Research, Chinese Academy of Agricultural Sciences (CAAS). With a profound academic background and extensive research experience in the field of plant pathology and microbial resistance, Dr. Wang has become a leading figure in her field. Over her career, she has focused on microbial resistance, antibacterial peptides, and the development of therapeutic strategies to combat infectious diseases, especially those involving multi-drug resistant pathogens. Dr. Wang’s work has been instrumental in bridging the gap between fundamental microbiology and applied agricultural practices, contributing to the development of feed-related solutions and sustainable agricultural practices. Her research is widely recognized through numerous publications in prestigious scientific journals, where she has co-authored over 80 papers.

Professional Profile

Education:

Dr. Wang Xiumin obtained her Ph.D. in Plant Pathology from Northwest Agriculture & Forestry University in 2006, after completing her Master’s and Bachelor’s degrees at the same institution in 2003 and 2000, respectively. Her academic training equipped her with in-depth knowledge in plant protection and pathology, laying a strong foundation for her career in agricultural sciences and microbiology. Her academic journey enabled her to focus on plant diseases, microbiology, and biotechnology, advancing her research in combating bacterial resistance in agricultural systems.

Professional Experience:

Dr. Wang Xiumin has accumulated extensive professional experience across various prestigious institutions. From 2006 to 2009, she worked as a Postdoctoral Fellow at Beijing Forestry University, engaging in critical research in plant pathology. Between 2009 and 2013, she served as an Assistant Researcher at the Feed Research Institute of CAAS. Since 2013, she has held the position of Associate Researcher at the same institute. In 2019-2020, she visited the School of Chemistry and Molecular Biosciences at the University of Queensland, further enhancing her expertise in molecular biosciences and plant pathology. Throughout her career, Dr. Wang has continually advanced her research while mentoring emerging scientists in her field.

Research Interests:

Dr. Wang’s research interests lie at the intersection of microbial resistance, plant pathology, and feed-related research. Her work primarily focuses on antibacterial peptides, microbial resistance mechanisms, and the development of therapeutic proteins and peptides. She has also contributed to studies on food safety, including the detoxification of mycotoxins, and has explored the therapeutic potential of marine peptides for bacterial infections. Dr. Wang’s research in microbial resistance and peptide-based therapeutics is crucial for advancing sustainable agricultural and clinical practices, particularly in the context of combating drug-resistant pathogens in both animals and humans.

Research Skills:

Dr. Wang Xiumin is highly skilled in a variety of research techniques including molecular biology, microbiology, and biotechnology. She has experience in the design and application of antibacterial peptides, the isolation and characterization of bioactive compounds, and the assessment of microbial resistance mechanisms. Her expertise also extends to advanced techniques in molecular cloning, protein expression, and peptide synthesis. Additionally, Dr. Wang is adept at using in vitro and in vivo models to study the effects of therapeutic peptides and other compounds on microbial infections. Her diverse skill set has been pivotal in advancing her research projects and making significant contributions to agricultural and health sciences.

Awards and Honors:

Dr. Wang Xiumin has received several accolades for her outstanding contributions to the field of plant pathology and microbiology. She has been recognized for her innovative research in microbial resistance and peptide-based therapeutics, receiving awards from various scientific and agricultural bodies in China. Her significant publications in high-impact journals such as Science of the Total Environment, Journal of Medicinal Chemistry, and Food Chemistry have cemented her reputation as a leading researcher in her field. Additionally, her collaborative work with international research institutes has earned her several fellowships, including her research visit to the University of Queensland, further acknowledging her impact on global agricultural science and medical microbiology.

Conclusion

Dr. Wang Xiumin demonstrates a strong and well-rounded research profile, with impressive publications and a proven ability to address complex issues in plant pathology and antimicrobial resistance. His work is highly relevant and impactful in agricultural and biomedical fields. His contributions place him as a strong candidate for the Excellence in Research Award. Expanding his industry collaborations and mentoring roles would elevate his profile further, making him an even more influential figure in his field.

Publication Top Notes

  1. Application of Lactobacillus plantarum and Pediococcus lactis on Lipid Metabolism, Anti-Inflammatory, and Fecal Microbiota in Cats
    • Authors: Shukun Liang, Xinshu Gu, Jintao Sun, Xiumin Wang, Hui Tao, Zhenlong Wang, Yougang Zhong, Jinquan Wang, Bing Han
    • Year: 2024
    • DOI: 10.3390/microorganisms12122446
  2. Application of Network Pharmacology, Molecular Docking, and In Vitro Experimental Evaluation to Decipher the Anti-Inflammatory Mechanisms of Cirsium japonicum
    • Authors: Jiaxue Wang, Hui Tao, Zhenlong Wang, Wei An, Ya Zhao, Bing Han, Jinquan Wang, Xiuzhu Sun, Xiumin Wang
    • Year: 2024
    • DOI: 10.3390/app14219687
  3. Simultaneous Degradation of AFB1 and ZEN by CotA Laccase from Bacillus subtilis ZJ-2019-1 in the Mediator-Assisted or Immobilization System
    • Authors: Boquan Gao, Wei An, Jianwen Wu, Xiumin Wang, Bing Han, Hui Tao, Jie Liu, Zhenlong Wang, Jinquan Wang
    • Year: 2024
    • DOI: 10.3390/toxins16100445
  4. Allergies to Allergens from Cats and Dogs: A Review and Update on Sources, Pathogenesis, and Strategies
    • Authors: Wei An, Ting Li, Xinya Tian, Xiaoxin Fu, Chunxiao Li, Zhenlong Wang, Jinquan Wang, Xiumin Wang
    • Year: 2024
    • DOI: 10.3390/ijms251910520
  5. Bacillus subtilis Simultaneously Detoxified Aflatoxin B1 and Zearalenone
    • Authors: Jianwen Wu, Zhenlong Wang, Wei An, Boquan Gao, Chunxiao Li, Bing Han, Hui Tao, Jinquan Wang, Xiumin Wang, Huanrong Li
    • Year: 2024
    • DOI: 10.3390/app14041589
  6. The Effect of Lactobacillus plantarum on the Fecal Microbiota, Short Chain Fatty Acids, Odorous Substances, and Blood Biochemical Indices of Cats
    • Authors: Bing Han, Shukun Liang, Jintao Sun, Hui Tao, Zhenlong Wang, Baosheng Liu, Xiumin Wang, Jie Liu, Jinquan Wang
    • Year: 2024
    • DOI: 10.3390/microorganisms12010091
  7. Comparison Study of Two Fumonisin-Degrading Enzymes for Detoxification in Piglets
    • Authors: Zhenlong Wang, Zonghao Lv, Tibor Czabany, Veronika Nagl, Rudolf Krska, Xiumin Wang, Bing Han, Hui Tao, Jie Liu, Jinquan Wang
    • Year: 2023
    • DOI: 10.3390/toxins16010003
  8. The Effect of Duck Bile Acid Extract on the Fecal Microbiota, Short Chain Fatty Acids, Fat Digestibility and Blood Biochemical Indices in Cats
    • Authors: Bing Han, Peng Zhao, Shukun Liang, Zhenlong Wang, Hui Tao, Xiumin Wang, Jie Liu, Jinquan Wang
    • Year: 2023
    • DOI: 10.3390/app13179713
  9. A Screening Model of Antibacterial Agents Based on Escherichia coli Cell-Division Protein
    • Authors: Qiuyu Fan, Jianwen Wu, Bolin Xi, Chunxiao Li, Xiumin Wang, Huanrong Li
    • Year: 2023
    • DOI: 10.3390/app13074493
  10. Mini-Review: Antibiotic-Resistant Escherichia coli from Farm Animal-Associated Sources
    • Authors: ChunMing Xu, Lingqiang Kong, Yonghong Liao, Yuan Tian, Qi Wu, Haosi Liu, Xiumin Wang
    • Year: 2022
    • DOI: 10.3390/antibiotics11111535

 

Lian-Wang Guo | Genetics and Molecular Biology| Best Researcher Award

Dr. Lian-Wang Guo | Genetics and Molecular Biology| Best Researcher Award

Professor at University of Virginia, United States

Dr. Lian-Wang Guo is a Professor of Biomedical Sciences at the University of Virginia with over 20 years of experience in vascular biology and biochemistry. His research primarily focuses on the role of epigenetic modulators in vascular diseases, particularly neointima-associated restenosis. He has been continuously funded by the NIH since 2012 and has published 48 peer-reviewed papers in the past six years, while also filing six patent applications. Dr. Guo’s innovative work includes developing biomimetic nanoplatforms for targeted drug delivery, which are currently in advanced trials for treating vascular conditions. His research integrates basic science with clinical applications, notably through collaboration with Dr. Craig Kent. Dr. Guo is recognized for his significant contributions to vascular epigenetics and has created a rigorous and inclusive training environment for young researchers. His work holds promise for advancing therapeutic strategies and improving clinical outcomes for vascular diseases.

Professional Profile

Education

Dr. Lian-Wang Guo’s educational background is rooted in biology and advanced plant physiology, providing a strong foundation for his extensive research career. He earned his Bachelor of Science degree in Biology from Xinjiang University in China in 1989, followed by a Master of Science in Plant Physiology from the prestigious Chinese Academy of Sciences in 1992. He continued his studies there, earning a Ph.D. in Plant Physiology and Biochemistry in 1995. Driven by a passion for genetics and biochemistry, Dr. Guo completed a postdoctoral fellowship at The Hebrew University of Jerusalem in 1998, where he broadened his research expertise in molecular biology. His educational journey reflects a commitment to understanding complex biological processes, which he has successfully applied to his pioneering work in vascular biology and epigenetics. Dr. Guo’s solid academic training has been instrumental in his innovative research contributions and leadership in biomedical sciences.

Professional Experience

Dr. Lian-Wang Guo is a tenured Professor of Biomedical Sciences at the University of Virginia, specializing in vascular biology and epigenetics. With over 20 years of research experience, Dr. Guo has developed an expertise in chromatin modulators and their role in vascular diseases, particularly in neointima-associated restenosis. He has been continuously funded by the NIH since 2012, and his prolific contributions include 48 peer-reviewed publications and multiple patents, reflecting his leadership in vascular epigenetics research. His laboratory employs advanced molecular techniques such as ChIPseq, RNAseq, bioinformatics, and innovative nanoplatforms for targeted drug delivery. Dr. Guo has also successfully fostered clinical collaborations, including the development of therapeutic interventions currently undergoing large animal trials, with preparations for human studies. A dedicated mentor, he has cultivated a rigorous training environment for students and fellows, helping them transition into independent research careers. His research has garnered numerous awards and recognition from prominent scientific organizations.

Research Interests

Lian-Wang Guo’s research interests center around the intersection of vascular biology, epigenetics, and targeted drug delivery. As a professor of Biomedical Sciences, his work focuses on understanding the role of chromatin modulators, such as EZH2, DOT1L, and BRD4, in vascular diseases, particularly neointima-associated restenosis. By uncovering how these epigenetic regulators influence disease-specific gene expression, he aims to develop precise therapeutic strategies that mitigate pathological vascular remodeling while preserving normal cellular functions. Dr. Guo is also deeply involved in translational research, advancing the use of biomimetic nanoplatforms for targeted, localized drug delivery. His lab has developed innovative nanotechnologies to deliver therapeutic agents to disease sites, aiming to enhance efficacy and minimize side effects. A key element of his research is the integration of basic science discoveries with clinical applications, as evidenced by his collaborations on vascular disease treatments currently in advanced stages of preclinical testing.

Lian-Wang Guo, Professor of Biomedical Sciences at the University of Virginia, has earned numerous prestigious awards and honors throughout his distinguished career. In 1996, he received the Award of Excellent Sci/Tech Articles from the Chinese Society of Plant Physiology. He has also been recognized with the University of Wisconsin-Madison Eye Research Institute Rapid Response Initiative Award (2008), the Morgridge Institute for Research Award (2014), and the New Investigator Award from the State of Wisconsin Partnership Program (2014). At The Ohio State University, he earned the Accelerator Award for Translation (2017). His editorial contributions include serving as Lead Guest Editor for Genes and Associate Editor for Frontiers in Cardiovascular Medicine. In 2023, he was elected as a Fellow of the American Heart Association (FAHA), and his outstanding research earned him recognition at the 2023 Research Achievement event at the University of Virginia, marking him as a leading figure in vascular biology and biomedical research.

Dr. Lian-Wang Guo’s extensive research contributions, particularly in vascular biology and epigenetics, position him as a leading scholar in biomedical sciences. His innovative work on chromatin modulators, specifically targeting epigenetic players like BRD4, EZH2, and DOT1L, has brought new insights into the treatment of neointimal-associated vascular diseases. Additionally, his development of nano-based, targeted drug delivery systems has shown promising translational potential, bridging the gap between basic science and clinical applications. With over 20 years of experience, numerous high-impact publications, NIH funding, and significant patents, Dr. Guo’s work is both cutting-edge and impactful. His mentorship of the next generation of scientists, as well as his collaborations with leading clinicians, further enhance his academic profile. While his contributions are already significant, a continued focus on clinical translation could maximize the impact of his research. Overall, Dr. Guo exemplifies the qualities of an outstanding researcher deserving of recognition.

 

Publication top noted
  • Article: Transmembrane protein TMEM97 and epigenetic reader BAHCC1 constitute an axis that supports pro-inflammatory cytokine expression
    Authors: Li, J., Shen, H., Guo, L.-W.
    Year: 2024
    Citations: 0
  • Article: miR579-3p is an inhibitory modulator of neointimal hyperplasia and transcription factors c-MYB and KLF4
    Authors: Xie, X., Shirasu, T., Li, J., Guo, L.-W., Kent, K.C.
    Year: 2023
    Citations: 3
  • Article: Neointima abating and endothelium preserving — An adventitia-localized nanoformulation to inhibit the epigenetic writer DOT1L
    Authors: Shirasu, T., Yodsanit, N., Li, J., Gong, S., Guo, L.-W.
    Year: 2023
    Citations: 1
  • Article: Targeted PERK inhibition with biomimetic nanoclusters confers preventative and interventional benefits to elastase-induced abdominal aortic aneurysms
    Authors: Yodsanit, N., Shirasu, T., Huang, Y., Gong, S., Wang, B.
    Year: 2023
    Citations: 2
  • Article: Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation
    Authors: Zhang, M., Li, J., Wang, Q., Miller, C.L., Guo, L.-W.
    Year: 2023
    Citations: 3
  • Article: Sphingoid Bases Regulate the Sigma-1 Receptor—Sphingosine and N,N’-Dimethylsphingosine Are Endogenous Agonists
    Authors: Li, J., Satyshur, K.A., Guo, L.-W., Ruoho, A.E.
    Year: 2023
    Citations: 3
  • Article: Retinal Photoreceptor Protection in an AMD-Related Mouse Model by Selective Sigma-1 or Sigma-2 Receptor Modulation
    Authors: Mavlyutov, T.A., Li, J., Liu, X., Pattnaik, B., Guo, L.-W.
    Year: 2022
    Citations: 4
  • Erratum: Correction: miR548ai antagonism attenuates exosome-induced endothelial cell dysfunction (Cell Death Discovery, (2021), 7, 1, (318), 10.1038/s41420-021-00720-9)
    Authors: Xie, X., Guo, L.-W., Kent, C.K.
    Year: 2022
    Citations: 0
  • Article: Differential Responses to Sigma-1 or Sigma-2 Receptor Ablation in Adiposity, Fat Oxidation, and Sexual Dimorphism
    Authors: Li, J., Félix-Soriano, E., Wright, K.R., Stanford, K.I., Guo, L.-W.
    Year: 2022
    Citations: 5
  • Article: SREBP1 regulates Lgals3 activation in response to cholesterol loading
    Authors: Li, J., Shen, H., Owens, G.K., Guo, L.-W.
    Year: 2022
    Citations: 9