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Dr. Tatiane Piedade de Souza | Transcriptomics | Young Scientist Award

Biologist at Federal University of Pará, Brazil

Tatiane Piedade de Souza is a dedicated molecular biologist based in Belém, Pará, Brazil, with a strong academic background, including a Ph.D. in Genetics and Molecular Biology from the Federal University of Pará. Her research focuses on pharmacogenetics and the epigenomics of neurodegenerative diseases, particularly her work on mitochondrial and inflammatory alterations in Parkinson’s disease. Currently employed at the Laboratory of Human and Medical Genetics, Tatiane conducts Next-Generation Sequencing (NGS) experiments and bioinformatics data analysis. With teaching experience at the high school and university levels, she effectively communicates complex biological concepts and mentors students in scientific projects. Her excellent work ethic, strong interpersonal communication skills, and emotional intelligence enhance her collaborative efforts in research. While her publication record could be expanded, Tatiane’s commitment to advancing scientific knowledge and her impactful research make her a promising candidate for the Research for Young Scientist Award.

Profile

Education

Tatiane Piedade de Souza has a robust educational background in the field of Biological Sciences. She graduated with a Bachelor’s degree in Biology from the Federal University of Pará in February 2018, where she conducted her undergraduate research on polymorphisms of CYP3A5 and GSTP1 genes related to pediatric Acute Lymphoblastic Leukemia susceptibility. She then pursued a Master’s degree in Genetics and Molecular Biology, completing it in February 2020. Her master’s research focused on the impact of polymorphisms in microRNA genes on the susceptibility to Acute Lymphoblastic Leukemia. Tatiane continued her academic journey, obtaining a Ph.D. in Genetics and Molecular Biology from the same institution in August 2024. Her doctoral research investigated gene co-expression networks that suggest mitochondrial and inflammatory alterations in Parkinson’s disease, reflecting her commitment to addressing critical health issues through advanced genetic research. This solid educational foundation has equipped her with essential skills and knowledge in molecular biology and genetics.

Professional Experience

Tatiane Piedade de Souza is a skilled molecular biologist currently employed at the Laboratory of Human and Medical Genetics (LGHM) at the Federal University of Pará, where she focuses on Next-Generation Sequencing (NGS) experiments, including DNA/RNA extraction, quality control, and library preparation. Her role involves conducting genomics and transcriptomics research, specifically examining gene co-expression networks related to neurodegenerative diseases such as Parkinson’s disease. Prior to this position, she worked as a biology teacher, developing and delivering engaging lesson plans for high school students, guiding them in scientific initiation projects, and preparing them for science fairs. Additionally, Tatiane has gained valuable experience in university teaching, preparing and executing lesson plans for undergraduate and graduate courses in biomedical science and genetics. Her background includes hands-on experience with animal models for pharmacogenetic studies, further enriching her expertise in molecular biology and genetics research.

Research Interest

Tatiane Piedade de Souza’s research interests primarily revolve around genetics and molecular biology, with a particular focus on pharmacogenetics and the epigenomics of neurodegenerative diseases. Her work aims to uncover the genetic and molecular mechanisms underlying conditions such as Parkinson’s disease, emphasizing the role of gene co-expression networks in mitochondrial and inflammatory alterations. By employing advanced techniques such as Next-Generation Sequencing (NGS) and bioinformatics data analysis, Tatiane seeks to identify genetic polymorphisms that may influence disease susceptibility and treatment responses. Additionally, she is passionate about bridging the gap between research and education, evidenced by her experience in teaching biology and mentoring students in scientific projects. Tatiane’s multidisciplinary approach combines laboratory research with educational outreach, reflecting her commitment to advancing knowledge in genetics while fostering the next generation of scientists. Through her work, she aims to contribute significantly to the understanding and treatment of complex genetic disorders.

Research Skills

Tatiane Piedade de Souza possesses a diverse range of research skills that enhance her contributions to molecular biology and genetics. With a strong foundation in Next-Generation Sequencing (NGS), she excels in DNA/RNA extraction, quality control, and library preparation, enabling her to conduct comprehensive genomic and transcriptomic analyses. Her expertise extends to bioinformatics, where she adeptly analyzes complex data sets, facilitating meaningful interpretations in her research on neurodegenerative diseases. Additionally, Tatiane’s background in pharmacogenetics equips her with the knowledge to investigate genetic factors influencing drug responses. Her hands-on experience with in vivo animal models further demonstrates her capability to conduct pharmacogenetic studies. Moreover, her strong writing skills enable her to effectively communicate her findings through project proposals and scientific articles. Overall, Tatiane’s research proficiency, combined with her collaborative spirit and teaching experience, positions her as a valuable asset in the scientific community.

Award and Recognition

Tatiane Piedade de Souza is an accomplished molecular biologist whose research has garnered attention in the fields of pharmacogenetics and neurodegenerative diseases. With a solid educational foundation, including a Ph.D. in Genetics and Molecular Biology from the Federal University of Pará, Tatiane has made significant contributions through her work on gene co-expression networks and their implications for Parkinson’s disease. She has been recognized for her exceptional skills in Next-Generation Sequencing and bioinformatics, facilitating advancements in understanding complex genetic interactions. Tatiane’s commitment to education is evident in her experience as a biology teacher, where she inspires students and fosters a passion for scientific inquiry. Her dedication to research and teaching has positioned her as a promising candidate for various awards and recognitions within the scientific community, reflecting her potential to make impactful contributions to molecular biology and genetics in the years to come.

Conclusion

Tatiane Piedade de Souza possesses a strong foundation in molecular biology and genetics, complemented by relevant research and teaching experience. Her work on neurodegenerative diseases and pharmacogenetics is particularly notable, showcasing her commitment to impactful research. While she has significant strengths, there are areas for growth, particularly in expanding her publication record and professional networking. Overall, she is a strong candidate for the Research for Young Scientist Award, with the potential for continued contributions to the scientific community.

Publication Top Notes

  1. Hypoglycaemic activity and molecular mechanisms of Caesalpinia ferrea Martius bark extract on streptozotocin-induced diabetes in Wistar rats
    • Authors: CFB Vasconcelos, HML Maranhão, TM Batista, EM Carneiro, F Ferreira
    • Year: 2011
    • Journal: Journal of Ethnopharmacology
    • Volume/Issue/Page: 137(3), 1533-1541
  2. Identification of NUDT15 gene variants in Amazonian Amerindians and admixed individuals from northern Brazil
    • Authors: JCG Rodrigues, TP Souza, LF Pastana, AM Ribeiro dos Santos
    • Year: 2020
    • Journal: PloS One
    • Volume/Issue/Page: 15(4), e0231651
  3. Pharmacogenomics and variations in the risk of toxicity during the consolidation/maintenance phases of the treatment of pediatric B-cell leukemia patients from an admixed population
    • Authors: DC de Carvalho, AV Wanderley, AMR Dos Santos, MR Fernandes
    • Year: 2018
    • Journal: Leukemia Research
    • Volume/Issue/Page: 74, 10-13
  4. Characterization of pharmacogenetic markers related to Acute Lymphoblastic Leukemia toxicity in Amazonian native Americans population
    • Authors: DC de Carvalho, AV Wanderley, AMR Dos Santos, FC Moreira
    • Year: 2020
    • Journal: Scientific Reports
    • Volume/Issue/Page: 10(1), 10292
  5. The Metabolization Profile of the CYP2D6 Gene in Amerindian Populations: A Review
    • Authors: LPC Leitão, TP Souza, JCG Rodrigues, MR Fernandes, S Santos
    • Year: 2020
    • Journal: Genes
    • Volume/Issue/Page: 11(3), 262
  6. Polymorphisms of xenobiotic-metabolizing and transporter genes, and the risk of gastric and colorectal cancer in an admixed population from the Brazilian Amazon
    • Authors: ANCL de Castro, MR Fernandes, DC de Carvalho, TP de Souza
    • Year: 2020
    • Journal: American Journal of Translational Research
    • Volume/Issue/Page: 12(10), 6626
  7. Influence of variants of the drosha, mir499a, and mir938 genes on susceptibility to acute lymphoblastic leukemia in an admixed population from the Brazilian Amazon
    • Authors: TP de Souza, DC de Carvalho, AV Wanderley, SM Fernandes
    • Year: 2020
    • Journal: American Journal of Translational Research
    • Volume/Issue/Page: 12(12), 8216
  8. Nuclear and mitochondrial genome, epigenome and gut microbiome: Emerging molecular biomarkers for Parkinson’s disease
    • Authors: G Fonseca Cabral, AP Schaan, GC Cavalcante, C Sena-dos-Santos
    • Year: 2021
    • Journal: International Journal of Molecular Sciences
    • Volume/Issue/Page: 22(18), 9839
  9. Association between the TPMT*3C (rs1142345) Polymorphism and the Risk of Death in the Treatment of Acute Lymphoblastic Leukemia in Children from the Brazilian Amazon
    • Authors: D Cardoso de Carvalho, L Pereira Colares Leitão, FAR Mello Junior
    • Year: 2020
    • Journal: Genes
    • Volume/Issue/Page: 11(10), 1132
  10. Association of genes ARID5B, CEBPE and folate pathway with acute lymphoblastic leukemia in a population from the Brazilian Amazon region
    • Authors: DC Carvalho, AV Wanderley, FARMJ Junior, AMR Dos Santos
    • Year: 2020
    • Journal: Leukemia Research Reports
    • Volume/Issue/Page: 13, 100188

 

 

 

 

Tatiane Piedade de Souza | Transcriptomics | Young Scientist Award

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