Ph.D. at Aichi Cancer Center Research Institute , Japan.
Dr. Tsukasa Nabekura is a prominent immunologist known for his groundbreaking research on natural killer (NK) cells. Since 2008, he has made significant contributions to understanding NK cell receptors and their roles in immune responses to viral infections, cancer, and tissue injury. His work has led to key insights into NK cell differentiation, function, and memory, as evidenced by his publications in high-impact journals like Immunity and Journal of Experimental Medicine. Dr. Nabekura’s research has global significance, with collaborations spanning institutions such as the University of California, San Francisco, and the University of Tsukuba, Japan. His achievements have been recognized with prestigious awards, including the Young Investigator Award from the Japanese Society of Immunology and the BEST FACULTY MEMBER award. Dr. Nabekura’s research continues to advance the field of immunology, with potential implications for therapeutic strategies in cancer and infectious diseases.
Dr. Tsukasa Nabekura’s educational background reflects a strong foundation in biological and medical sciences. He completed his Bachelor of Science in Biology in March 2003, followed by a Master of Arts in Medical Science in March 2005, both from the University of Tsukuba, Japan. Dr. Nabekura then pursued a Ph.D. in Medicine at the same institution, graduating in March 2008. His commitment to advancing his expertise continued with postdoctoral research at the University of Tsukuba, where he focused on Immunology and completed his postdoc in October 2011. Further enhancing his qualifications, he undertook an additional postdoctoral fellowship at the University of California, San Francisco, from October 2014. This extensive educational journey equipped Dr. Nabekura with a deep understanding of immunology and cell biology, setting the stage for his influential research on natural killer (NK) cells and their roles in immune responses.
Dr. Tsukasa Nabekura has built a distinguished career in immunology with a focus on natural killer (NK) cells. After completing his postdoctoral research in immunology at the University of California, San Francisco, he returned to Japan as an Assistant Professor in the Life Science Center of Tsukuba Advanced Research Alliance at the University of Tsukuba. His expertise led him to roles at the Life Science Center for Survival Dynamics and the Division of Immune Response at the Aichi Cancer Center Research Institute. Dr. Nabekura’s professional trajectory reflects a strong commitment to advancing immunological research and understanding NK cell biology. His career is marked by his significant contributions to the field through his research on NK cell function and memory, collaborative efforts with leading scientists, and the recognition he has received through various awards and honors.
Dr. Tsukasa Nabekura’s research interests center on the intricate roles of natural killer (NK) cells in immune responses. Since 2008, his work has delved into how NK receptors and associated molecules influence innate and adaptive immunity against viral infections, cancer, and acute tissue injury. His research has elucidated the pivotal role of DNAX accessory molecule-1 (DNAM-1) in NK cell memory differentiation and its impact on acute graft-versus-host disease. Dr. Nabekura has also investigated how activating receptors enhance NK cell functions and memory during infections. His recent studies focus on the regulatory functions of Themis2 in NK cell memory and antitumor activity. By exploring these aspects, Dr. Nabekura aims to advance our understanding of immune responses and contribute to the development of new therapeutic strategies for treating cancer and viral diseases.
Dr. Tsukasa Nabekura possesses a diverse range of advanced research skills that underscore his expertise in immunology. His proficiency in cellular and molecular immunology is evident from his extensive work on natural killer (NK) cells, including their receptors and associated molecules. He has demonstrated exceptional skills in experimental design and execution, particularly in studying NK cell function during viral infections and cancer. Dr. Nabekura’s expertise extends to cutting-edge techniques in cell biology, including flow cytometry, immunohistochemistry, and cytokine profiling. His ability to collaborate with leading researchers and institutions further highlights his strong skills in cross-disciplinary research and team-based science. Additionally, Dr. Nabekura’s experience in securing research fellowships and grants reflects his competence in research proposal development and project management. His comprehensive approach to studying immune responses and his successful publication record illustrate his high level of research acumen and dedication to advancing scientific knowledge.
Awards and Recognition
Dr. Nabekura has received numerous awards, including the Young Investigator Award from the Japanese Society of Immunology and the BEST FACULTY MEMBER award at the University of Tsukuba. These accolades reflect his outstanding contributions and recognition within the scientific community.
Conclusion
Dr. Tsukasa Nabekura’s exceptional research on NK cells and immune responses demonstrates his profound impact on the field of immunology. His contributions to understanding immune mechanisms, his collaborative efforts, and his recognition through various awards underscore his suitability for the Research for Best Researcher Award. His work continues to advance scientific knowledge and has the potential to influence therapeutic strategies for infectious diseases and cancer.
Publications Top Notes
- THEMIS2 Impairs Antitumor Activity of NK Cells by Suppressing Activating NK Receptor Signaling
- Authors: E.A. Deborah, T. Nabekura, K. Shibuya, A. Shibuya
- Year: 2024
- Themis2 regulates natural killer cell memory function and formation
- Authors: T. Nabekura, E.A. Deborah, S. Tahara, M. Muratani, A. Shibuya
- Year: 2023
- Citations: 4
- DNAM-1 Immunoreceptor Protects Mice from Concanavalin A-Induced Acute Liver Injury by Reducing Neutrophil Infiltration
- Authors: S. Matsuo, T. Nabekura, K. Matsuda, K. Shibuya, A. Shibuya
- Year: 2023
- Citations: 1
- Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches
- Authors: T. Asahi, S. Abe, G. Cui, H. Ohno, K. Ikuta
- Year: 2023
- Citations: 4
- The CD16 and CD32b Fc-gamma receptors regulate antibody-mediated responses in mouse natural killer cells
- Authors: O.A. Aguilar, M.D.R. Gonzalez-Hinojosa, J.S. Arakawa-Hoyt, T. Nabekura, L.L. Lanier
- Year: 2023
- Citations: 8
- Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming
- Authors: S. Aizawa, K. Nishimura, G.S. Mondejar, Y. Hayashi, K. Hisatake
- Year: 2022
- Citations: 3
- Erratum: Corrigendum to selective expression of a C-type lectin receptor, Clec12b, on skin mast cells
- Authors: A. Iijima, K. Kanemaru, Y. Wang, S. Tahara-Hanaoka, A. Shibuya
- Year: 2021
- Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells
- Authors: A. Iijima, K. Kanemaru, Y. Wang, S. Tahara-Hanaoka, A. Shibuya
- Year: 2021
- Type 1 innate lymphoid cells: Soldiers at the front line of immunity
- Authors: T. Nabekura, A. Shibuya
- Year: 2021
- Citations: 17
- ILC1: guardians of the oral mucosa against enemy viruses
- Authors: T. Nabekura, A. Shibuya
- Year: 2021
- Citations: 7