Professor at Yanbian University, China
Dr. Lan Hong, a Professor in the Department of Physiology and Pathophysiology at Yanbian University’s College of Medicine, has dedicated her career to advancing knowledge in cardiovascular physiology, with a specialized focus on cardiac protection mechanisms and stem cell therapy. With over 18 years of experience, Dr. Hong’s research addresses critical challenges in cardiovascular health, particularly in understanding and treating ischemia-reperfusion injuries and myocardial infarction. She has made substantial contributions to the field through high-impact publications, collaborative research initiatives, and conference presentations. As a recognized figure in her field, she has also served as a visiting scholar at Texas A&M University-Commerce, where she expanded her work on regenerative medicine, specifically focusing on cardiac-induced RNA and pluripotent stem cells. Dr. Hong’s research is well-cited, with an H-index of 10 and a citation count of over 300, reflecting her influence in cardiac physiology research. Her extensive involvement in academic conferences, journal reviews, and mentoring has bolstered her reputation as a leader in cardiovascular research. She is also recognized through multiple awards and invitations to present her research, which underscores her commitment to advancing the understanding and treatment of cardiovascular diseases.
Professional Profile
Education
Dr. Lan Hong’s educational journey is anchored in her commitment to understanding the intricacies of cardiovascular physiology. She earned her PhD in Physiology from Yanbian University in 2012, where she also completed her MSc in the same field in 2009. Prior to her postgraduate studies, she graduated with a degree in Clinical Medicine from Yanbian University in 2006, which laid the foundation for her subsequent research in cardiac health. Her academic path reflects a deep specialization in cardiac physiology, particularly in exploring protective mechanisms for the heart and developing innovative treatments for cardiovascular diseases. Throughout her education, Dr. Hong cultivated a robust theoretical and practical understanding of physiology, providing a strong foundation for her later research on myocardial infarction and stem cell therapy. Her scholarly background, coupled with hands-on experience in clinical medicine, has greatly enriched her approach to research, enabling her to bridge the gap between theoretical knowledge and clinical application in her ongoing studies.
Professional Experience
Dr. Lan Hong has built a distinguished career as a cardiovascular researcher, currently serving as a Professor at the College of Medicine at Yanbian University, where she has worked since 2013. She initially joined the university’s Department of Physiology and Pathophysiology as an Assistant Professor, where her research began to focus on ischemia-reperfusion injury and cardiac fibrosis mechanisms. Her career includes international experience as a visiting scholar and postdoctoral researcher at Texas A&M University-Commerce from 2017 to 2018. During her tenure there, she collaborated on groundbreaking work using cardiac-inducing RNA and stem cell technology for post-infarction heart repair. Dr. Hong’s role as an educator and mentor is integral to her professional experience, as she has supervised graduate students, organized research conferences, and contributed as a reviewer for respected journals. Her professional trajectory reflects a consistent dedication to advancing cardiovascular health and supporting academic development in her field, cementing her reputation as a respected academic and researcher in cardiovascular physiology.
Research Interests
Dr. Lan Hong’s research interests center on cardiovascular physiology, with a particular emphasis on mechanisms of cardiac protection and regeneration. Her work seeks to address key challenges in treating myocardial infarction and mitigating ischemia-reperfusion injury. One of her primary research interests is exploring molecular pathways such as the Sirt1/Nrf2/ATF3/4 axis and the role of ferroptosis in cardiac injury. Additionally, Dr. Hong is committed to advancing stem cell therapy, specifically investigating the regenerative potential of induced pluripotent stem cells in cardiac repair. Her studies also delve into the role of long non-coding RNAs (lncRNAs) in modulating cellular responses to injury and in promoting cardiomyocyte regeneration. By targeting these cellular pathways, Dr. Hong aims to develop novel therapeutic approaches that offer improved outcomes for patients with cardiovascular conditions. Her research interests reflect a balanced approach that combines molecular biology, regenerative medicine, and clinical application, making significant strides in cardiovascular health advancements.
Research Skills
Dr. Lan Hong’s research skills are rooted in a robust knowledge of cardiovascular physiology, paired with technical expertise in cellular and molecular biology techniques. She is proficient in various lab methodologies essential to cardiac physiology research, including in vitro and in vivo models for studying ischemia-reperfusion injury and myocardial infarction. Dr. Hong’s work with stem cells, particularly induced pluripotent stem cells, requires advanced skills in cellular reprogramming and RNA-mediated gene expression techniques. Her proficiency extends to molecular techniques such as Western blotting, immunohistochemistry, and real-time PCR, which she utilizes to investigate gene expression patterns and protein signaling in cardiac tissues. Her ability to perform complex experimental procedures, analyze data critically, and interpret results within the context of cardiovascular health has made her research impactful and well-regarded. Dr. Hong’s research skills are complemented by her collaborative approach, which has facilitated cross-disciplinary studies and allowed her to mentor students effectively, contributing to the next generation of cardiovascular researchers.
Awards and Honors
Throughout her career, Dr. Lan Hong has received recognition for her contributions to cardiovascular research. Her work has earned her multiple awards, reflecting her expertise and influence in cardiac physiology. She has been invited to present her findings at national and international conferences, showcasing her research on ischemia-reperfusion injury and stem cell therapy. Her role as an invited speaker demonstrates the high regard in which her peers hold her work and highlights her contributions to advancing cardiovascular health. Additionally, Dr. Hong’s editorial and peer-review roles for respected journals underscore her commitment to maintaining rigorous standards in scientific research and her influence in the academic community. Her research achievements, high-impact publications, and the positive impact of her mentorship have solidified her standing as a leader in cardiovascular physiology. Her recognition through these awards and honors underscores her dedication to her field and highlights her impact on the scientific understanding of cardiac health and disease.
Conclusion
Lan Hong’s extensive research and contributions in cardiovascular physiology, along with her impactful publications, make her a strong candidate for the Best Researcher Award. Her international experience, academic achievements, and innovative work in cardiac protection mechanisms are commendable. Addressing minor gaps in industry collaboration and expanding her professional presence may further strengthen her profile for future recognitions. Overall, her dedication to advancing cardiovascular health and her achievements make her highly deserving of the award.
Publications Top Notes
- Synthesis and antibacterial evaluation of rhodanine-based 5-aryloxy pyrazoles against selected methicillin-resistant and quinolone-resistant Staphylococcus aureus (MRSA and QRSA)”
Authors: MX Song, CJ Zheng, XQ Deng, LP Sun, Y Wu, L Hong, YJ Li, Y Liu, …
Journal: European Journal of Medicinal Chemistry, 60, 376-385
Year: 2013
Citations: 57
- “MAPK and PI3K pathways regulate hypoxia-induced atrial natriuretic peptide secretion by controlling HIF-1 alpha expression in beating rabbit atria”
Authors: Q Zhang, B Cui, H Li, P Li, L Hong, L Liu, D Ding, X Cui
Journal: Biochemical and Biophysical Research Communications, 438 (3), 507-512
Year: 2013
Citations: 38
- “Atrial natriuretic peptide prevents the mitochondrial permeability transition pore opening by inactivating glycogen synthase kinase 3β via PKG and PI3K in cardiac H9c2 cells”
Authors: L Hong, J Xi, Y Zhang, W Tian, J Xu, X Cui, Z Xu
Journal: European Journal of Pharmacology, 695 (1-3), 13-19
Year: 2012
Citations: 37
- “Synthesis and biological evaluation of 5-aryloxypyrazole derivatives bearing a rhodanine-3-aromatic acid as potential antimicrobial agents”
Authors: CJ Zheng, MX Song, LP Sun, Y Wu, L Hong, HR Piao
Journal: Bioorganic & Medicinal Chemistry Letters, 22 (23), 7024-7028
Year: 2012
Citations: 35
- “Synthesis and positive inotropic activity of N-(4, 5-dihydro-[1, 2, 4] triazolo [4, 3-a] quinolin-7-yl)-2-(piperazin-1-yl) acetamide derivatives”
Authors: CB Zhang, X Cui, L Hong, ZS Quan, HR Piao
Journal: Bioorganic & Medicinal Chemistry Letters, 18 (16), 4606-4609
Year: 2008
Citations: 26
- “Adenosine A2 receptor activation ameliorates mitochondrial oxidative stress upon reperfusion through the posttranslational modification of NDUFV2 subunit of complex I in the heart”
Authors: J Xu, X Bian, Y Liu, L Hong, T Teng, Y Sun, Z Xu
Journal: Free Radical Biology and Medicine, 106, 208-218
Year: 2017
Citations: 22
- “Ethanol attenuates sensory stimulus-evoked responses in cerebellar granule cells via activation of GABAA receptors in vivo in mice”
Authors: G Wu, H Liu, J Jin, L Hong, Y Lan, CP Chu, DL Qiu
Journal: Neuroscience Letters, 561, 107-111
Year: 2014
Citations: 19
- “Ouabain stimulates atrial natriuretic peptide secretion via the endothelin-1/ETB receptor-mediated pathway in beating rabbit atria”
Authors: L Liu, L Hong, L Yu, H Li, D Ding, S Jin, X Cui
Journal: Life Sciences, 90 (19-20), 793-798
Year: 2012
Citations: 16
- “Cathepsins in the extracellular space: Focusing on non-lysosomal proteolytic functions with clinical implications”
Authors: H Wang, A Inoue, Y Lei, H Wu, L Hong, XW Cheng
Journal: Cellular Signalling, 103, 110531
Year: 2023
Citations: 13