Dongsheng Di | Epidemiology | Best Researcher Award

Mr. Dongsheng Di | Epidemiology | Best Researcher Award

Ph.D. Candidate at Epidemiology, Huazhong University of Science and Technology Tongji Medical College, China

Dongsheng Di is a prolific researcher whose work primarily focuses on environmental health, rheumatoid arthritis, osteoporosis, and related diseases. Their research includes studies on the effects of air pollution on cardiovascular mortality, the impact of long-term outdoor air pollution on rheumatoid arthritis, and the identification of genetic susceptibility loci for rheumatoid arthritis. They have also investigated the associations between multiple metals and bone mineral density, as well as the effects of various dietary factors and environmental exposures on osteoporosis risk. Additionally, Dongsheng Di has conducted research on the microbiota-gut-brain axis and its relationship to osteoporosis risk. Their work demonstrates a strong commitment to understanding the complex interplay between environmental factors, genetics, and health outcomes.

Professional Profiles:

Education:

Dr. Qi Wang holds a Master of Science (M.S.) in Epidemiology and Biology Statistics (2020) and a Bachelor of Science (B.S.) in Preventive Medicine (2017) from Anhui Medical University. They completed their Doctoral degree in Public Health and Preventive Medicine in 2022.

Research:

Dr. Qi Wang has contributed to several research projects, including the National Natural Science Foundation of China (NSFC) Program focusing on the role and biological mechanisms of gut microbiota regulation on postmenopausal osteoporosis (PMOP) during the trans-menopause period. Another project involved the Wuhan Municipal Health Commission Preventive Medicine Research Special, investigating the association between volatile organic compounds exposure and bone health in middle-aged and older populations. Dr. Wang also participated in the National Natural Science Foundation of China (NSFC) Program, Wuhan Interaction with Stockholm Evidence-based Research (WISER) project, which focused on health perspectives in the older population facing the SARS-CoV-2 outbreak. Additionally, Dr. Wang contributed to the Hubei Provincial Natural Science Foundation Project, screening and studying the mechanisms of Semaphorin 3A (Sema3A) mutations associated with susceptibility to postmenopausal osteoporosis in women. Finally, Dr. Wang was involved in the National Key R&D Program of China, sub-project, focusing on key technology research on risk assessment of food contaminants.

Experience:

Dr. Qi Wang’s professional experience includes serving as a Research Team Member on various projects related to public health and preventive medicine. Dr. Wang also completed a doctoral degree in Public Health and Preventive Medicine, focusing on an association study of plasma metals and plasma metabolites with the risk of primary osteoporosis. Furthermore, Dr. Wang has been actively involved in research projects such as evaluating credible capacity and SOE for generalized energy storage under multiple uncertainties and cooperative control of multiple dispersed bidirectional power resources. Dr. Wang’s research contributions have significantly advanced the understanding of these complex issues and have the potential to impact public health and environmental policies.

Interest:

Dr. Qi Wang’s research interests lie in the key technologies and applications of energy storage, flexibility, and resilience enhancement of smart grids. They are also interested in demand-side management and power pricing, as well as the operation and control of agricultural networks. Dr. Wang’s diverse research interests reflect a commitment to addressing complex challenges in the fields of energy, environment, and public health, with a focus on improving sustainability and efficiency in these areas.

Awards:

Dr. Qi Wang has received several awards and honors for their outstanding contributions to research and academia. These include being named a Fellow of the Research for an 8-month stay at Université Paris Saclay, France, in 2018. Additionally, they have been awarded the International Association of Geoanalysis (IAG) bursary Award for attending the Geoanalysis 2022 conference in Freiberg, Germany, and have been selected for The Goldschmidt Grant Program for early career delegates for attending the Goldschmidt 2023 conference in Lyon, France. These awards recognize Dr. Wang’s excellence in their field and their dedication to advancing scientific knowledge and understanding.

Publications:

  1. Association between air pollution and cardiovascular mortality in Hefei, China: a time-series analysis
    • Authors: C Zhang, R Ding, C Xiao, Y Xu, H Cheng, F Zhu, R Lei, D Di, Q Zhao, …
    • Journal: Environmental Pollution
    • Year: 2017
    • Citations: 117
  2. Long-term exposure to outdoor air pollution and the risk of development of rheumatoid arthritis: a systematic review and meta-analysis
    • Authors: D Di, L Zhang, X Wu, R Leng
    • Journal: Seminars in Arthritis and Rheumatism
    • Year: 2020
    • Citations: 38
  3. Identification of new susceptibility loci associated with rheumatoid arthritis
    • Authors: RX Leng, DS Di, J Ni, XX Wu, LL Zhang, XF Wang, RS Liu, Q Huang, …
    • Journal: Annals of the Rheumatic Diseases
    • Year: 2020
    • Citations: 33
  4. Associations of multiple metals with bone mineral density: A population-based study in US adults
    • Authors: M Wei, Y Cui, H Zhou, W Song, D Di, R Zhang, Q Huang, J Liu, Q Wang
    • Journal: Chemosphere
    • Year: 2021
    • Citations: 25
  5. Genetic variant in microRNA-146a gene is associated with risk of rheumatoid arthritis
    • Authors: LL Zhang, XX Wu, XF Wang, DS Di, Q Huang, RS Liu, ZW Shuai, DQ Ye, …
    • Journal: Annals of Medicine
    • Year: 2021
    • Citations: 13
  6. Manganese, iron, copper, and selenium co-exposure and osteoporosis risk in Chinese adults
    • Authors: M Wei, Q Huang, Y Dai, H Zhou, Y Cui, W Song, D Di, R Zhang, C Li, …
    • Journal: Journal of Trace Elements in Medicine and Biology
    • Year: 2022
    • Citations: 10
  7. The effect of probiotics, prebiotics, and synbiotics on CD4 counts in HIV-infected patients: a systematic review and meta-analysis
    • Authors: YS Fu, QS Chu, AA Ashuro, DS Di, Q Zhang, XM Liu, YG Fan
    • Journal: BioMed Research International
    • Year: 2020
    • Citations: 10
  8. Multiple vitamin co-exposure and mortality risk: a prospective study
    • Authors: Y Cui, H Zhou, M Wei, W Song, D Di, R Zhang, S Wei, J Liu, Q Wang
    • Journal: Clinical Nutrition
    • Year: 2022
    • Citations: 9
  9. Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population
    • Authors: D Di, C Li, Y Dai, M Wei, S Wang, W Song, H Zhou, Y Cui, R Zhang, …
    • Journal: Frontiers in Microbiology
    • Year: 2021
    • Citations: 9
  10. Exposure to phenols, chlorophenol pesticides, phthalate and PAHs and mortality risk: A prospective study based on 6 rounds of NHANES
    • Authors: D Di, R Zhang, H Zhou, M Wei, Y Cui, J Zhang, T Yuan, Q Liu, T Zhou, …
    • Journal: Chemosphere
    • Year: 2023
    • Citations: 7

Dr. Liton Kumar Saha | Cancer | Excellence in Research

Dr. Liton Kumar Saha | Cancer | Excellence in Research

Post-doctoral Fellow at Cancer, National Cancer Institute, United States

👨‍🎓He remarkable academic journey, extensive research contributions, and dedication to the field of psychology are truly commendable. Your wealth of knowledge and diverse skill set reflect a deep commitment to understanding and addressing critical issues such as bullying, inclusion, and socialization.

🔬 He successful completion of a PhD in Psychology, along with the numerous advanced courses and workshops, showcases your continuous pursuit of excellence and expertise in your field.

🏆 The awards and recognitions, including the First Place in the Poster Award at the University of Stavanger, underscore the impact of your research and the high regard it holds in the academic community.

Professional Profiles:

Education/Research:

From July 2019 to the present, [Name] has served as a Postdoctoral Fellow (Visiting) at the Developmental Therapeutics Branch, National Cancer Institute, NIH. His research focuses on PARP1, TOP3A, Replication, DNA repair, DNA-protein crosslink, mitochondria, and related topics. He earned his Ph.D. degree in Medical Sciences from the Graduate School of Medicine, Kyoto University, Kyoto, Japan, from 2016 to 2019. His Ph.D. research was conducted in the Department of Radiation Genetics, where he investigated the novel function of genes in DNA repair and DNA damage tolerance. He achieved this by generating mutants in human cell lines using CRISPR/Cas9 and TALEN technology. Prior to his Ph.D., he completed his Master’s degree in medical sciences at the Graduate School of Medicine, Kyoto University, Kyoto, Japan, from 2014 to 2016. His research during this period focused on DNA repair and toxicology, specifically utilizing DNA-repair-deficient cells to identify genotoxins with greater sensitivity and characterizing DNA lesions caused by industrial chemical compounds. He received his Master’s degree in Biochemistry and Molecular Biology from the Faculty of Biological Sciences, University of Dhaka, Dhaka, Bangladesh, in 2007-2008. His dissertation was on the phenotypic and molecular characterization of Salmonella Typhi isolated recently in Bangladesh. He also holds a Bachelor’s degree in Biochemistry and Molecular Biology from the Faculty of Biological Sciences, University of Dhaka, Dhaka, Bangladesh, achieved with distinction, from 2001 to 2006.

🔬 Visiting Research Associate

  • Dr. Samuel H. Wilson lab
  • Genome Integrity and Structure Biology Laboratory
  • National Institute of Environmental Health Sciences (NIEHS), NIH, USA
  • March 2017-May 2017
  • Research Topic: Established In-vitro base excision repair (BER) of CPD lesion-containing DNA (cell-extract based and enzyme-mediated both).

🔬 Visiting Research Associate

  • Professor Ian D Hickson lab
  • Center for Chromosome Stability
  • Institute of Cellular and Molecular Medicine
  • Faculty of Health and Medical Sciences
  • University of Copenhagen, Copenhagen, Denmark
  • September 2015- November 2017
  • Research Topic: Performed and established the protocol for the detection of ultrafine DNA bridges (UFBs) in human TK6 cells using MRE11 mutant.

🔬 Research Assistant

  • Department of Radiation Genetics
  • Graduate School of Medicine, Kyoto University, Kyoto, Japan
  • August 2013- March 2014

🔬 Research Officer

  • International Center for Diarrheal Diseases Research, Bangladesh (ICDDR, B)
  • Dhaka, Bangladesh
  • 2009-2012

Awards:

During the period of 2014 to 2019, [Name] was awarded a Scholarship from the Training Program of Leaders for Integrated Medical System: for Fruitful Healthy-Longevity Society in Japan. Additionally, in 2018, he received a research grant from the Training Program of Leaders for Integrated Medical System at Kyoto University, Japan. Similarly, in both 2017 and 2016, he was also awarded research grants from the same Training Program at Kyoto University, Japan.

Publications:

  1. BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II–DNA complexes
    • Authors: H Sasanuma, M Tsuda, S Morimoto, LK Saha, MM Rahman, Y Kiyooka, …
    • Citations: 81
    • Year: 2018
  2. Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC)
    • Authors: Y Sun, S Saha, W Wang, LK Saha, SYN Huang, Y Pommier
    • Citations: 72
    • Year: 2020
  3. Novel and highly potent ATR inhibitor M4344 kills cancer cells with replication stress, and enhances the chemotherapeutic activity of widely used DNA damaging agents
    • Authors: U Jo, IS Senatorov, A Zimmermann, LK Saha, Y Murai, SH Kim, …
    • Citations: 64
    • Year: 2021
  4. Debulking of topoisomerase DNA-protein crosslinks (TOP-DPC) by the proteasome, non-proteasomal and non-proteolytic pathways
    • Authors: Y Sun, LK Saha, S Saha, U Jo, Y Pommier
    • Citations: 56
    • Year: 2020
  5. SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors
    • Authors: U Jo, Y Murai, S Chakka, L Chen, K Cheng, J Murai, LK Saha, …
    • Citations: 34
    • Year: 2021
  6. Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1–DNA complexes
    • Authors: LK Saha, Y Murai, S Saha, U Jo, M Tsuda, S Takeda, Y Pommier
    • Citations: 22
    • Year: 2021
  7. Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells
    • Authors: LK Saha, M Wakasugi, S Akter, R Prasad, SH Wilson, N Shimizu, …
    • Citations: 21
    • Year: 2020
  8. The ARK assay is a sensitive and versatile method for the global detection of DNA-protein crosslinks
    • Authors: Q Hu, N Klages-Mundt, R Wang, E Lynn, LK Saha, H Zhang, M Srivastava, …
    • Citations: 21
    • Year: 2020
  9. UBC13-mediated ubiquitin signaling promotes removal of blocking adducts from DNA double-strand breaks
    • Authors: R Akagawa, HT Trinh, LK Saha, M Tsuda, K Hirota, S Yamada, A Shibata, …
    • Citations: 18
    • Year: 2020