Prof. AHM Nurun Nabi | Genetic Analyses | Outstanding Scientist Award

Professor at Genetic Analyses, University of Dhaka, Bangladesh

Professor A.H.M. Nurun Nabi is a distinguished scholar in the Department of Biochemistry and Molecular Biology at the University of Dhaka, Bangladesh. His expertise lies in protein expression, protein-protein interactions, and cell culture techniques. He has conducted extensive research on health hazards in various occupational settings and arsenic toxicity in the Bangladeshi population. Prof. Nabi has received several scholarships and awards for his contributions to biochemistry research.

Professional Profiles:

Academic Qualifications:

Prof. AHM Nurun Nabi completed his Doctor of Philosophy in Biochemistry from the laboratory of Animal Biochemistry, United Graduate School of Agricultural Science, Gifu University, Japan, in 2006. Prior to this, he obtained a Master of Philosophy in Biochemistry from the Department of Biochemistry and Molecular Biology, University of Dhaka, Bangladesh, in 2000. His academic journey began with a Master of Science in Biochemistry from the same department at the University of Dhaka in 1996, where he graduated with First class honors. He also holds a Bachelor of Science in Biochemistry from the University of Dhaka, earned in 1995 with First class honors. Prof. AHM Nurun Nabi’s educational foundation includes a Higher Secondary Certificate in Science from Rajshahi College, Rajshahi, in 1992, and a Secondary School Certificate in Science from Rajshahi Collegiate School, Rajshahi, in 1990, both achieved with First division distinctions.

Professional:

Prof. AHM Nurun Nabi has a rich history of professional attachments in the field of biochemistry and molecular biology. He has been serving as a Professor in the Department of Biochemistry and Molecular Biology at the University of Dhaka, Bangladesh, since October 2013. Additionally, he holds the position of Joint Secretary at The Bangladesh Society for Biochemistry and Molecular Biology, Bangladesh, a role he has fulfilled since 2016. His dedication to education is evident in his role as a Student Advisor at the Department of Biochemistry and Molecular Biology, University of Dhaka, Bangladesh, from December 2010 to 2018. Prof. AHM Nurun Nabi’s contributions extend internationally, as he serves as an Honorary Visiting Professor at the Faculty of Applied Biological Sciences, Gifu University, Japan, a position he has held since April 2014. Prior to his current roles, he served as an Associate Professor in the Department of Biochemistry and Molecular Biology at the University of Dhaka from June 2011 to October 09, 2013. He also has experience as a Visiting Associate Professor at the Faculty of Applied Biological Sciences, Gifu University, Japan, from October 2009 to October 2010. His academic journey began as an Assistant Professor at the Department of Biochemistry and Molecular Biology, University of Dhaka, Bangladesh, from August 2006 to June 2011. Before that, he served as a Lecturer in the same department from March 2001 to July 2006. Additionally, he has contributed as Honorary Teaching Staff at the Department of Genetic Engineering and Biotechnology, University of Dhaka, Bangladesh, from January 2007 to June 2007.

Awards:

Prof. AHM Nurun Nabi has been recognized for his academic excellence and research contributions through various prestigious awards and scholarships. He received Merit Scholarships from the People’s Republic of Bangladesh for the periods 1990-92 and 1992-95, highlighting his exceptional academic performance. His pursuit of higher education was further supported by a Ph.D. Scholarship awarded by the Japan Government, which enabled him to conduct advanced research in biochemistry and molecular biology at the laboratory of Animal Biochemistry, United Graduate School of Agricultural Science, Gifu University, Japan, from 2003 to 2006. After completing his Ph.D., he was awarded a JSPS Postdoctoral Fellowship by the Japan Society for Promotion of Science, which allowed him to continue his research in Japan from 2007 to 2009, further enhancing his expertise in the field. In recognition of his contributions to academia, he was awarded a Fellowship from the Japan Student Service Organization (JASSO) in 2018, underscoring his commitment to academic excellence and research. These awards and scholarships reflect Prof. AHM Nurun Nabi’s dedication to advancing knowledge in biochemistry and molecular biology.

Research Experience:

During his Post-doctoral Research Fellowship, Prof. AHM Nurun Nabi conducted research focusing on in vitro protein expression, protein-protein interactions using Nanobiotechnology techniques, and protein purification. He also gained expertise in cell culture techniques, including troubleshooting, and studied angiogenesis. His primary research interests centered on the functional studies of Renin, Prorenin, and (Pro)renin receptors, with a particular focus on the binding mechanisms of renin and prorenin to (pro)renin receptors. Additionally, he has extensive experience in protein purification, cell culture, and the expression of specific genes for functional studies on the cell membrane. This experience has provided him with a comprehensive understanding of cellular processes and molecular interactions. Prof. AHM Nurun Nabi’s research also extends to public health issues. He conducted research to determine the health status, including biochemical and cellular conditions, of garage workers. His work aimed to raise awareness among workers regarding possible health hazards associated with working in such environments. Furthermore, he has conducted research on human samples collected from arsenic-endemic regions. His research focused on the nutritional, biochemical, and immunological aspects of arsenic toxicity in the Bangladeshi population chronically exposed to arsenic through drinking water. This research culminated in a thesis entitled “Immunological and Biochemical Investigations in Human Arsenic Toxicity,” submitted for the partial fulfillment of his M.Phil degree.

Dr. Liton Kumar Saha | Cancer | Excellence in Research

Post-doctoral Fellow at Cancer, National Cancer Institute, United States

👨‍🎓He remarkable academic journey, extensive research contributions, and dedication to the field of psychology are truly commendable. Your wealth of knowledge and diverse skill set reflect a deep commitment to understanding and addressing critical issues such as bullying, inclusion, and socialization.

🔬 He successful completion of a PhD in Psychology, along with the numerous advanced courses and workshops, showcases your continuous pursuit of excellence and expertise in your field.

🏆 The awards and recognitions, including the First Place in the Poster Award at the University of Stavanger, underscore the impact of your research and the high regard it holds in the academic community.

Professional Profiles:

Education/Research:

From July 2019 to the present, [Name] has served as a Postdoctoral Fellow (Visiting) at the Developmental Therapeutics Branch, National Cancer Institute, NIH. His research focuses on PARP1, TOP3A, Replication, DNA repair, DNA-protein crosslink, mitochondria, and related topics. He earned his Ph.D. degree in Medical Sciences from the Graduate School of Medicine, Kyoto University, Kyoto, Japan, from 2016 to 2019. His Ph.D. research was conducted in the Department of Radiation Genetics, where he investigated the novel function of genes in DNA repair and DNA damage tolerance. He achieved this by generating mutants in human cell lines using CRISPR/Cas9 and TALEN technology. Prior to his Ph.D., he completed his Master’s degree in medical sciences at the Graduate School of Medicine, Kyoto University, Kyoto, Japan, from 2014 to 2016. His research during this period focused on DNA repair and toxicology, specifically utilizing DNA-repair-deficient cells to identify genotoxins with greater sensitivity and characterizing DNA lesions caused by industrial chemical compounds. He received his Master’s degree in Biochemistry and Molecular Biology from the Faculty of Biological Sciences, University of Dhaka, Dhaka, Bangladesh, in 2007-2008. His dissertation was on the phenotypic and molecular characterization of Salmonella Typhi isolated recently in Bangladesh. He also holds a Bachelor’s degree in Biochemistry and Molecular Biology from the Faculty of Biological Sciences, University of Dhaka, Dhaka, Bangladesh, achieved with distinction, from 2001 to 2006.

🔬 Visiting Research Associate

Dr. Samuel H. Wilson lab
Genome Integrity and Structure Biology Laboratory
National Institute of Environmental Health Sciences (NIEHS), NIH, USA
March 2017-May 2017
Research Topic: Established In-vitro base excision repair (BER) of CPD lesion-containing DNA (cell-extract based and enzyme-mediated both).

🔬 Visiting Research Associate

Professor Ian D Hickson lab
Center for Chromosome Stability
Institute of Cellular and Molecular Medicine
Faculty of Health and Medical Sciences
University of Copenhagen, Copenhagen, Denmark
September 2015- November 2017
Research Topic: Performed and established the protocol for the detection of ultrafine DNA bridges (UFBs) in human TK6 cells using MRE11 mutant.

🔬 Research Assistant

Department of Radiation Genetics
Graduate School of Medicine, Kyoto University, Kyoto, Japan
August 2013- March 2014

🔬 Research Officer

International Center for Diarrheal Diseases Research, Bangladesh (ICDDR, B)
Dhaka, Bangladesh
2009-2012

Awards:

During the period of 2014 to 2019, [Name] was awarded a Scholarship from the Training Program of Leaders for Integrated Medical System: for Fruitful Healthy-Longevity Society in Japan. Additionally, in 2018, he received a research grant from the Training Program of Leaders for Integrated Medical System at Kyoto University, Japan. Similarly, in both 2017 and 2016, he was also awarded research grants from the same Training Program at Kyoto University, Japan.

Publications:

BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II–DNA complexes
- Authors: H Sasanuma, M Tsuda, S Morimoto, LK Saha, MM Rahman, Y Kiyooka, …
- Citations: 81
- Year: 2018
Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC)
- Authors: Y Sun, S Saha, W Wang, LK Saha, SYN Huang, Y Pommier
- Citations: 72
- Year: 2020
Novel and highly potent ATR inhibitor M4344 kills cancer cells with replication stress, and enhances the chemotherapeutic activity of widely used DNA damaging agents
- Authors: U Jo, IS Senatorov, A Zimmermann, LK Saha, Y Murai, SH Kim, …
- Citations: 64
- Year: 2021
Debulking of topoisomerase DNA-protein crosslinks (TOP-DPC) by the proteasome, non-proteasomal and non-proteolytic pathways
- Authors: Y Sun, LK Saha, S Saha, U Jo, Y Pommier
- Citations: 56
- Year: 2020
SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors
- Authors: U Jo, Y Murai, S Chakka, L Chen, K Cheng, J Murai, LK Saha, …
- Citations: 34
- Year: 2021
Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1–DNA complexes
- Authors: LK Saha, Y Murai, S Saha, U Jo, M Tsuda, S Takeda, Y Pommier
- Citations: 22
- Year: 2021
Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells
- Authors: LK Saha, M Wakasugi, S Akter, R Prasad, SH Wilson, N Shimizu, …
- Citations: 21
- Year: 2020
The ARK assay is a sensitive and versatile method for the global detection of DNA-protein crosslinks
- Authors: Q Hu, N Klages-Mundt, R Wang, E Lynn, LK Saha, H Zhang, M Srivastava, …
- Citations: 21
- Year: 2020
UBC13-mediated ubiquitin signaling promotes removal of blocking adducts from DNA double-strand breaks
- Authors: R Akagawa, HT Trinh, LK Saha, M Tsuda, K Hirota, S Yamada, A Shibata, …
- Citations: 18
- Year: 2020