Mr. Royston Liew | Medicine and Dentistry | Best Researcher Award
Student at Duke-NUS Medical School, Singapore
Dr. Liew Yew Meng Royston is an emerging researcher with a background in Chemical and Biomolecular Engineering, focusing on the molecular mechanisms underlying Hepatocellular Carcinoma (HCC), particularly in None-B-None-C HCC patients. His research integrates engineering principles with biological sciences, offering a novel approach to understanding complex disease pathways, such as bile acid homeostasis. Dr. Royston is proactive in his research endeavors, having initiated wet-lab experiments months in advance under the guidance of Professor Pierce Chow. His work has led to significant findings in the role of post-translational modifications in liver-gut homeostasis. In addition to his research, Dr. Royston has been recognized for his innovation with multiple patents and awards, including the National Runner-Up in the James Dyson Award for his work in vertical farming. His interdisciplinary approach and commitment to advancing medical research make him a promising figure in the field of oncology and biomedical engineering.
Education
Dr. Liew Yew Meng Royston holds a Bachelor of Engineering (Honours) in Chemical and Biomolecular Engineering from Nanyang Technological University, Singapore, where he studied from 2018 to 2022. His academic training provided a strong foundation in engineering principles, which he has effectively applied to his research in the biomedical field. During his undergraduate studies, Dr. Royston demonstrated a keen interest in integrating engineering with biological systems, laying the groundwork for his current research in Hepatocellular Carcinoma (HCC). His educational journey was marked by academic excellence, earning him a place on the Dean’s List for the 2018/2019 academic year. The interdisciplinary nature of his education has equipped Dr. Royston with the skills to approach complex biological problems with precision and innovation, making significant contributions to his field. His commitment to academic and research excellence continues to drive his pursuit of advanced knowledge in medicine and biomedical engineering.
Dr. Liew Yew Meng Royston has demonstrated considerable professional experience in both research and innovation. He is currently focused on Hepatocellular Carcinoma (HCC) research, specifically None-B-None-C HCC (NBNC HCC), where he applies his background in chemical and biomolecular engineering to investigate bile acid homeostasis and its implications for liver function. Before beginning his Duke-NUS Phase 3 Scholarly Research Project, Dr. Royston proactively engaged in preliminary research with Professor Pierce Chow, resulting in significant novel findings. His research approach integrates engineering principles with biological systems, employing techniques such as molecular pathway modeling and process optimization. Beyond his research, Dr. Royston has made notable contributions to the field of vertical farming, with a patent for a modular hydroponic system and recognition through awards like the James Dyson Award and the APAC CEO of the Year Awards. His expertise reflects a blend of scientific rigor and innovative problem-solving.
Dr. Liew Yew Meng Royston’s research interest centers on elucidating the molecular and cellular mechanisms underlying Hepatocellular Carcinoma (HCC), specifically focusing on None-B-None-C Hepatocellular Carcinoma (NBNC HCC). His work involves investigating the dysregulation of bile acid homeostasis pathways and their impact on liver function in NBNC HCC patients. By applying principles from Chemical and Biomolecular Engineering, Dr. Royston integrates metabolomic, microbiomic, and transcriptomic data to identify critical alterations in disease mechanisms. His research explores the role of post-translational modifications, particularly acetylation of the FXR protein, in influencing bile acid production and liver-gut homeostasis. Additionally, he investigates the effects of highly processed diets on the microbiome and their subsequent role in HCC development. Dr. Royston’s interdisciplinary approach aims to deepen understanding of HCC and develop innovative strategies for its treatment, blending engineering precision with advanced biological research.
Dr. Liew Yew Meng Royston possesses a diverse skill set tailored to his research in Hepatocellular Carcinoma (HCC). His skills include advanced techniques in metabolomics, microbiomics, and transcriptomics, which are essential for analyzing complex biological data. Dr. Royston is proficient in molecular pathway modeling and process optimization, applying engineering principles to biological systems. His expertise extends to wet-lab experimentation, including the study of post-translational modifications of proteins and their effects on gene transcription. Additionally, Dr. Royston employs systems-level approaches to integrate various biological and biochemical data, enhancing the precision and depth of his research. His proactive approach to research, demonstrated by initiating preliminary work and securing foundational results, further highlights his commitment and technical capabilities in addressing complex biomedical challenges.
Dr. Liew Yew Meng Royston has received significant recognition for his contributions to research and innovation. Notably, he was awarded the National Runner-Up position in the James Dyson Award in 2022 for his work on vertical farming, highlighting his innovative approach to urban agriculture. His invention of a modular hydroponic farming apparatus was patented internationally, underscoring his inventive capabilities. In addition to these achievements, Dr. Royston received the APAC CEO of the Year Awards for Most Innovative Agribusiness CEO in 2022, reflecting his impact on the agribusiness sector. His research efforts have also been supported by several grants, including the SSG Tech POC Grant of $250,000 and the SSG Founder’s Startup Grant of $50,000. Dr. Royston’s academic excellence was recognized through his inclusion on the Dean’s List at Nanyang Technological University for the academic year 2018/2019, further attesting to his dedication and outstanding performance in his field.
Liew Yew Meng Royston demonstrates significant potential as a researcher with a strong interdisciplinary approach and innovative mindset. His proactive research efforts, combined with his engineering background, position him as a promising candidate for the Best Researcher Award. However, enhancing his publication record and securing research grants could further solidify his standing in the research community.
Publication Top Notes
Diagnostic laparoscopy for pre-operative selection of patients with known peritoneal carcinomatosis for CRS-HIPEC: A systematic review and meta-analysis
- Authors: Ang, A.J.Y., Liew, R.Y.M., Aw, V.Z.J., Chia, C.S., Shannon, N.B.
- Year: 2024
- Journal: European Journal of Surgical Oncology
- Volume: 50
- Issue: 11
- Article Number: 108623