Risa Yamada | Health Professions | Best Researcher Award

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Ms. Risa Yamada | Health Professions | Best Researcher Award

Researcher from National Center of Neurology and Psychiatry, Japan

Risa Yamada is an esteemed Chief Researcher at the Department of Preventive Intervention for Psychiatric Disorders, National Institute of Mental Health, National Center of Neurology and Psychiatry, Japan. Her research primarily focuses on neuropsychopharmacology, epidemiology, and neurophysiology in patients with psychiatric disorders such as schizophrenia, mood disorders, and substance abuse. She is renowned for her pioneering work in the epidemiology of gambling disorders, exploring the impact of comorbid behavioral addiction. Her research has yielded significant insights into the effectiveness of serotonin-5-HT1A receptor partial agonists for cognitive enhancement in schizophrenia, with findings published in prestigious journals. Additionally, she is conducting cutting-edge research on transcranial photobiomodulation to ameliorate cognitive deficits in schizophrenia. Yamada has made notable contributions to the understanding of depression severity and the role of adverse childhood experiences in mood disorders. With a background in clinical psychology and neuropsychopharmacology, she is a rising leader in the field of psychiatric research.

Professional Profile

Education

Risa Yamada completed her medical education at the Jikei University School of Medicine, earning her Ph.D. in February 2023. Prior to this, she received a Bachelor of Science degree from Toho University in 2011 and a Master of Psychology from Teikyo University in 2018. Throughout her educational journey, she focused on the intersection of clinical psychology and psychiatry, particularly in understanding the neuropsychological aspects of psychiatric disorders. Her academic development laid a strong foundation for her subsequent research career. In addition to her medical degrees, Yamada holds certifications as a Clinical Psychologist (2019) and a Public Psychologist (2019), which further demonstrate her expertise and commitment to advancing psychological and psychiatric research. These educational qualifications, coupled with her practical research experience, allow Yamada to contribute significantly to the development of new treatment strategies for psychiatric conditions, particularly those related to cognitive dysfunction and behavioral addictions.

Professional Experience

Risa Yamada currently serves as the Chief Researcher at the Department of Preventive Intervention for Psychiatric Disorders at the National Institute of Mental Health, part of the National Center of Neurology and Psychiatry in Tokyo, Japan. She has been in this role since September 2021 and has been instrumental in leading research focused on cognitive impairments in psychiatric conditions such as schizophrenia. Yamada’s career began as a Research Associate in the Department of Mental Disorder Research at the National Center of Neurology and Psychiatry from 2018 to 2021, where she investigated depression severity and its links to adverse childhood experiences and coping styles. Prior to her current position, she conducted a doctoral research project at Jikei University, where she explored the relationship between gambling disorder and psychiatric conditions. Her extensive experience spans multiple research settings, with her work having a significant impact on clinical understanding and treatment development for various psychiatric conditions. Yamada’s role as a researcher and educator also extends to her involvement in several leading academic societies in psychiatry and neuropsychopharmacology.

Research Interests

Risa Yamada’s research interests lie at the intersection of clinical psychology, psychiatry, and neuropsychopharmacology. She is deeply engaged in studying the cognitive and neurophysiological aspects of psychiatric disorders, particularly schizophrenia, mood disorders, and behavioral addictions such as gambling disorders. Her work focuses on the use of neuropsychological methods to explore the biological and psychological underpinnings of these conditions, with a particular emphasis on cognitive impairment. One of her notable research projects involves studying the augmentation of cognitive function in schizophrenia using serotonin-5-HT1A receptor partial agonists, a promising avenue for improving psychotic symptoms and cognitive deficits. Additionally, Yamada is investigating the potential of transcranial photobiomodulation, a non-invasive brain stimulation technique, to address cognitive impairments in patients with schizophrenia. She also explores the relationship between adverse childhood experiences and mood disorders, with the goal of identifying effective biomarkers and treatments for negative valence in psychiatric conditions. Her research aims to advance both theoretical understanding and practical interventions for these prevalent and challenging mental health conditions.

Research Skills

Risa Yamada possesses a diverse and advanced skill set in clinical research, particularly in the fields of neuropsychopharmacology, epidemiology, and neurophysiology. She is proficient in conducting meta-analyses and cross-sectional studies, particularly related to psychiatric disorders and cognitive dysfunction. Her expertise in neuropsychological methods allows her to investigate complex interactions between psychological traits and psychiatric conditions. Yamada is skilled in using clinical scales and neurophysiological tools, such as skin conductivity measures, to assess psychological traits like interoception and alexithymia in relation to psychiatric conditions. Furthermore, she has experience in neuroimaging techniques, including the use of transcranial photobiomodulation for brain stimulation. Yamada’s work with behavioral addiction, particularly gambling disorders, demonstrates her ability to apply epidemiological methods to mental health research. She is also adept at analyzing large-scale clinical data sets and using statistical models to explore the relationship between psychiatric symptoms and demographic variables. These research skills enable her to lead impactful studies that contribute both to the scientific community and to practical applications in the treatment of psychiatric disorders.

Awards and Honors

Risa Yamada has received recognition for her contributions to psychiatric research, particularly in the areas of neuropsychopharmacology and behavioral addiction. She has been awarded several academic honors, including recognition for her groundbreaking research on gambling disorders, which was the first of its kind in Japan. Her work on cognitive enhancement therapies for schizophrenia has been published in high-impact journals, earning her a reputation as a leader in the field. While she has not yet received large-scale awards, her growing recognition within the academic community and her role as Chief Researcher at the National Institute of Mental Health reflect her increasing influence. Yamada’s contributions to psychiatric research have been acknowledged through invitations to present her findings at prestigious international conferences. She is also a member of several leading professional societies, including the Collegium Internationale Neuro-Psychopharmacologicum and the Japanese Society of Neuropsychopharmacology, further solidifying her status as a respected researcher.

Conclusion

Risa Yamada is a highly promising and accomplished researcher in the field of psychiatry, with a focus on neuropsychopharmacology, neurophysiology, and epidemiology. Her work has already made a significant impact, particularly in the understanding of cognitive dysfunction in schizophrenia and gambling disorders. With a robust educational background and extensive professional experience, Yamada is well-positioned to continue contributing to the advancement of psychiatric research. Her innovative approach to non-invasive brain stimulation, alongside her focus on biomarkers for psychiatric conditions, highlights her potential for further breakthroughs. While her research is primarily centered on schizophrenia and mood disorders, expanding her focus to other psychiatric conditions would enhance the breadth of her contributions. With continued growth in international collaboration and further emphasis on translational research, Yamada has the potential to make a lasting impact on both clinical practice and scientific understanding in the field of psychiatry.

Publications Top Notes

  • Clinical Significance of Psychiatric Comorbidities Among Outpatients With Gambling Disorder in Japan: A 12-Month Follow-Up Study
    Authors: Yamada, R., Stickley, A., Shigeta, M., Miyata, H.
    Year: 2025

  • Semantic memory disorganization linked to social functioning in patients with schizophrenia
    Authors: Wada, A., Sumiyoshi, C., Yoshimura, N., Hashimoto, R., Matsumoto, J., Stickley, A., Yamada, Y., Kikuchi, A., Kubota, R., Matsui, M., Nakachi, K., Fujimaki, C., Adachi, L., Yamada, R., Sumiyoshi, T.
    Year: 2025

  • Autistic trait severity in early schizophrenia: Role in subjective quality of life and social functioning
    Authors: Wada, A., Yamada, R., Yamada, Y., Sumiyoshi, C., Hashimoto, R., Matsumoto, J., Kikuchi, A., Kubota, R., Matsui, M., Nakachi, K., Fujimaki, C., Adachi, L., Stickley, A., Yoshimura, N., Sumiyoshi, T.
    Year: 2025

  • Problematic gambling and psychotic-like experiences: Findings from Japan
    Authors: Stickley, A., Shirama, A., Yamada, R., Sumiyoshi, T.
    Year: 2024

  • Augmentation therapy with serotonin1A receptor partial agonists on neurocognitive function in schizophrenia: A systematic review and meta-analysis
    Authors: Yamada, R., Wada, A., Stickley, A., Yokoi, Y., Sumiyoshi, T.
    Year: 2023

  • Effect of 5-HT1A Receptor Partial Agonists of the Azapirone Class as an Add-On Therapy on Psychopathology and Cognition in Schizophrenia: A Systematic Review and Meta-Analysis
    Authors: Yamada, R., Wada, A., Stickley, A., Yokoi, Y., Sumiyoshi, T.
    Year: 2023

  • Prevalence and Clinical Significance of Psychiatric Comorbidities With Gambling Disorder in 12 Clinical Settings in Japan
    Authors: Yamada, R., Miyashita, K., Hashimoto, T. M., et al.
    Year: 2023

  • Discrepancy between Clinician-rated and Self-reported Depression Severity is Associated with Adverse Childhood Experience, Autistic-like Traits, and Coping Styles in Mood Disorders
    Authors: Yamada, R., Fujii, T., Hattori, K., et al.
    Year: 2023

  • The relationship between severity of drug problems and perceived interdependence of drug use and sexual intercourse among adult males in drug addiction rehabilitation centers in Japan
    Authors: Yamada, R., Shimane, T., Kondo, A., Yonezawa, M., Matsumoto, T.
    Year: 2021

Didem Tezen | Medicine and Dentistry | Best Researcher Award

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Dr. Didem Tezen | Medicine and Dentistry | Best Researcher Award

Istanbul University- Cerrahpasa, Cerrahpasa Faculty of Medicine, Turkey

Dr. Didem Tezen is a dedicated neurologist and researcher with a strong academic background and extensive experience in clinical neurology. She has contributed significantly to the field through her research on neuromuscular disorders, dementia, movement disorders, and neurogenetics. With multiple publications in reputable journals, she has demonstrated expertise in both clinical and molecular neuroscience. Dr. Tezen’s research focuses on the genetic and biochemical mechanisms underlying neurological diseases, aiming to advance diagnostic and therapeutic approaches. She has worked at prestigious institutions, including Istanbul University-Cerrahpaşa and Bakırköy Dr. Sadi Konuk Training and Research Hospital, and currently serves at Oltu State Hospital in Erzurum, Turkey. Her work is highly regarded for its impact on understanding rare neuromuscular syndromes, neuroinflammatory pathways, and neurodegeneration. She actively collaborates with leading experts in neurology and has played a key role in pioneering studies on biomarkers for dementia and genetic mutations in movement disorders. Dr. Tezen’s commitment to scientific discovery and her clinical expertise make her a valuable contributor to the field of neurology. Her growing international presence and dedication to translational research place her among the emerging leaders in neurological research and patient care.

Professional Profile

Education

Dr. Didem Tezen has pursued a distinguished academic journey in medicine and neurology, building a solid foundation for her research and clinical practice. She completed her medical education at Istanbul University, Istanbul Faculty of Medicine from 2011 to 2017, where she developed her fundamental medical knowledge and clinical skills. After graduating, she advanced her expertise by specializing in neurology at Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, between 2018 and 2024. This rigorous residency program provided her with extensive experience in managing a wide range of neurological conditions, including neurodegenerative diseases, neuromuscular disorders, and cerebrovascular diseases. During her studies, she actively participated in clinical research projects and collaborated with experienced faculty members, allowing her to gain practical knowledge in neurophysiology, neuroimaging, and genetic neurology. Her educational background has played a crucial role in shaping her research interests, particularly in biomarker discovery, genetic analysis, and neuroinflammatory mechanisms in neurological disorders. Currently, she continues to apply her knowledge and expand her expertise as a practicing neurologist, while also engaging in ongoing research in her field. Her academic achievements and commitment to lifelong learning highlight her dedication to advancing neurological science and patient care.

Professional Experience

Dr. Didem Tezen has accumulated extensive clinical and research experience throughout her career in neurology. She began her professional journey at Bakırköy Dr. Sadi Konuk Training and Research Hospital, where she worked from 2017 to 2018, gaining firsthand experience in diagnosing and treating a variety of neurological conditions. This period provided her with essential clinical skills and exposure to neurology emergencies and complex neurological disorders. From 2018 to 2024, she further honed her expertise at Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Neurology Department, where she was involved in both clinical neurology and research. During this time, she contributed to several groundbreaking studies focusing on neurodegenerative diseases, neuromuscular disorders, and molecular neurology. She collaborated with esteemed researchers and specialists in neurophysiology, genetics, and electrophysiology, leading to several high-impact publications. As of 2024, Dr. Tezen has been serving as a neurologist at Oltu State Hospital in Erzurum, Turkey, where she continues to provide specialized care to patients with complex neurological disorders. Her clinical expertise, combined with her strong research background, allows her to integrate the latest scientific advancements into patient treatment, making her a highly valued physician and researcher in the field of neurology.

Research Interests

Dr. Didem Tezen’s research interests are primarily focused on the genetic and biochemical mechanisms of neurological diseases, aiming to improve both diagnostic and therapeutic approaches. One of her key areas of interest is neurodegeneration, particularly the role of biomarkers and neuroinflammatory pathways in dementia and Alzheimer’s disease. Her research has explored the clinical significance of YKL-40, VILIP-1, and inflammatory cytokines in neurodegenerative disorders, shedding light on their potential use as biomarkers for disease progression. She is also deeply engaged in studying neuromuscular diseases, with a focus on congenital myasthenic syndromes, hereditary polyneuropathies, and motor neuron diseases. Her investigations into genetic mutations associated with these disorders have provided critical insights into their pathophysiology. Additionally, she has contributed to research on movement disorders, examining rare cases of ADCY5 gene mutations and cerebrotendinous xanthomatosis. Dr. Tezen is also interested in clinical neurophysiology, particularly the application of electromyography (EMG) and nerve conduction studies in diagnosing neuromuscular and movement disorders. Her multidisciplinary approach, integrating genetics, neuroinflammation, and electrophysiology, positions her as a forward-thinking researcher in the field of neurology.

Research Skills

Dr. Didem Tezen possesses a diverse set of research skills that enable her to conduct high-quality scientific investigations in neurology. She is proficient in neurogenetics, with expertise in analyzing genetic mutations related to neuromuscular diseases and movement disorders. Her ability to integrate molecular genetics and clinical findings has significantly contributed to understanding rare neurological conditions. She is also skilled in biomarker research, particularly in the context of dementia and neurodegeneration. Her experience in measuring serum biomarkers, neuroinflammatory markers, and neurodegenerative proteins has advanced the field’s understanding of disease progression and potential treatment targets. In clinical neurophysiology, she has expertise in performing and interpreting electrophysiological tests, such as EMG and nerve conduction studies, which are essential for diagnosing neuromuscular disorders. Additionally, her research involves advanced neuroimaging techniques, including MRI analysis of brain volume changes in dementia patients. Her ability to design clinical studies, analyze statistical data, and collaborate with interdisciplinary teams further enhances her research capabilities. Her strong academic writing skills have also enabled her to publish multiple research papers in peer-reviewed journals, reinforcing her reputation as an accomplished researcher.

Awards and Honors

Dr. Didem Tezen has been recognized for her outstanding contributions to neurology research through several awards and honors. She has received institutional recognition for her work in biomarker discovery and neurogenetics, contributing to a deeper understanding of neurodegenerative and neuromuscular disorders. Her research on biomarkers in dementia and neuroinflammatory pathways has been highly regarded in neurology conferences and academic circles. She has also played a key role in multi-disciplinary research teams that have advanced the field of neuromuscular genetics. In addition to her scientific achievements, Dr. Tezen’s clinical excellence and commitment to patient care have earned her commendations from senior neurologists and faculty members. Her dedication to both research and clinical neurology sets her apart as a well-rounded physician-scientist. With her growing body of work and increasing international presence, she is poised to receive further recognition for her contributions to neurology and neuroscience research in the years to come.

Conclusion

Dr. Didem Tezen is a highly accomplished neurologist and researcher with a strong background in neuromuscular disorders, neurodegeneration, and neurogenetics. Her extensive research output, clinical expertise, and multidisciplinary approach make her a valuable asset to the field of neurology. Her contributions to biomarker discovery, genetic analysis, and electrophysiology have advanced our understanding of neurological diseases, earning her recognition among peers. While she has already established a strong foundation, further expanding her international collaborations, securing research funding, and increasing first-author publications could elevate her to greater scientific prominence. Overall, Dr. Tezen is a deserving candidate for the Best Researcher Award, and her dedication to scientific excellence will continue to have a significant impact on neurology research and patient care.

Scientific Activities

  1. Tezen D, Koçhan Kızılkılıç E, Akkan Suzan A, et al. 2025.

    • Correlation between serum YKL-40 and VILIP 1 levels and brain volume in dementia patients.

  2. Tezen D, Khojakulov Z, Gündüz A, Deymeer F, Demirbilek V, Başak AN. 2024.

    • Clinical, electrophysiological, and genetic analysis of a family with two rare neuromuscular disorders: congenital myasthenic syndrome and hereditary polyneuropathy.

  3. Tezen D, Kızılkılıç EK, Erener N, Khojakulov Z, Demirbilek V, Başak AN. 2025.

    • Experience with salbutamol treatment in a family with congenital myasthenia due to CHRNE mutation.

  4. Tezen D, Savrun F. 2023.

    • Alt Motor Nöron Hastalıkları, in Türkiye Klinikleri Nöroloji Özel Sayı-Motor Nöron Hastalıkları, edited by Nurten Uzun Adatepe.

  5. Gulmammadli N, Konukoğlu D, Merve Kurtuluş E, Tezen D, Ibrahim Erbay M, Bozluolçay M. 2022.

    • Serum Sirtuin-1, HMGB1-TLR4, NF-KB and IL-6 levels in Alzheimer’s: The Relation Between Neuroinflammatory Pathway and Severity of Dementia.

  6. Tezen D, Gunduz A, Erdemir Kiziltan M, Yalcinkaya C, Kiziltan G. 2022.

    • ADCY5 gene mutation: a case report.

  7. Tezen D, Şimşir G, Çokar Ö, Demirbilek V, Başak AN, Yapıcı Z. 2022.

    • Four Turkish families with hyperekplexia: A missense mutation and the exon 1-7 deletion in the GLRA1 gene.

  8. Aktuglu Zeybek C, Gunduz A, Enver EO, Tezen D, Kiykim E, Kızıltan ME. 2020.

    • Movement disorders in the early-diagnosed cerebrotendinous xanthomatosis: An electrophysiological study.

  9. Benbir Şenel G, Tezen D, Tekgül Ş, Başak AN. 2020.

    • Co-existence of Mutations in PRRT2 and ABCC6 Genes in a Turkish Family.